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Volumn 3, Issue 4, 2005, Pages 377-384

High-throughput screening of 11β-hydroxysteroid dehydrogenase type 1 scintillation proximity assay format

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTISONE; ENZYME INHIBITOR; GLUCOCORTICOID; HYDROCORTISONE;

EID: 27144542109     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2005.3.377     Document Type: Article
Times cited : (14)

References (15)
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    • Seckl JR, Walker BR: 11β-Hydroxysteroid dehydrogenase type 1 - a tissue-specific amplifier of glucocorticoid action. Endocrinology 2001;142;1371-1376.
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    • Seckl, J.R.1    Walker, B.R.2
  • 2
    • 1542780747 scopus 로고    scopus 로고
    • Enzymology and molecular biology of glucocorticoid metabolism in humans
    • Blum A, Maser E: Enzymology and molecular biology of glucocorticoid metabolism in humans. Prog Nucleic Acids Res Mol Biol 2003;75:173-216.
    • (2003) Prog. Nucleic Acids Res. Mol. Biol. , vol.75 , pp. 173-216
    • Blum, A.1    Maser, E.2
  • 3
    • 0024789306 scopus 로고
    • Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase
    • Agarwal AK, Monder C, Eckstein B, White PC: Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase. J Biol Chem 1989;264:18939-18943.
    • (1989) J. Biol. Chem. , vol.264 , pp. 18939-18943
    • Agarwal, A.K.1    Monder, C.2    Eckstein, B.3    White, P.C.4
  • 6
    • 0035798621 scopus 로고    scopus 로고
    • Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11β-hydroxysteroid dehydrogenase type 1 null mice
    • Morton NM, Holmes MC, Fievet C, Staels B, Tailleux A, Mullins JJ, Seckl JR: Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11β-hydroxysteroid dehydrogenase type 1 null mice. J Biol Chem 2001;276:41293-41300
    • (2001) J. Biol. Chem. , vol.276 , pp. 41293-41300
    • Morton, N.M.1    Holmes, M.C.2    Fievet, C.3    Staels, B.4    Tailleux, A.5    Mullins, J.J.6    Seckl, J.R.7
  • 10
    • 0037238379 scopus 로고    scopus 로고
    • Effects of the 11β-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes
    • Andrews RC, Rooyackers O, Walker BR: Effects of the 11β-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes. J Clin Endocrinol Metab 2003;88:285-291.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 285-291
    • Andrews, R.C.1    Rooyackers, O.2    Walker, B.R.3
  • 11
    • 0037133133 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase type 1 from human liver: Dimerization and enzyme cooperativity support its postulated role as glucocorticoid reductase
    • Maser E, Volker B, Friebertshauser J: 11β-Hydroxysteroid dehydrogenase type 1 from human liver: Dimerization and enzyme cooperativity support its postulated role as glucocorticoid reductase. Biochemistry 2002;41:2459-2465.
    • (2002) Biochemistry , vol.41 , pp. 2459-2465
    • Maser, E.1    Volker, B.2    Friebertshauser, J.3
  • 12
    • 0344844573 scopus 로고    scopus 로고
    • A rapid screening assay for inhibitors of 11β-hydroxysteroid dehydrogenases (11β-HSD): Flavanone selectively inhibits 11β-HSD1 reductase activity
    • Schweizer RAS, Atanasov AG, Frey BM, Odermatt A: A rapid screening assay for inhibitors of 11β-hydroxysteroid dehydrogenases (11β-HSD): flavanone selectively inhibits 11β-HSD1 reductase activity. Mol Cell Endocrinol 2003; 212:41-49.
    • (2003) Mol. Cell. Endocrinol. , vol.212 , pp. 41-49
    • Schweizer, R.A.S.1    Atanasov, A.G.2    Frey, B.M.3    Odermatt, A.4
  • 13
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    • Development and application of a scintillation proximity assay for identification of selective inhibitors of 11β-hydroxysteroid dehydrogenase
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.