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Volumn 53, Issue 7, 2000, Pages 497-501

Current understanding of the pathophysiology of thrombotic thrombocytopenic purpura

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CALCIUM; CYCLOSPORIN; FIBRIN; FIBRINOGEN; FIBRINOGEN RECEPTOR; GLYCOPROTEIN; LACTATE DEHYDROGENASE; MITOMYCIN C; ORAL CONTRACEPTIVE AGENT; PADGEM PROTEIN; PROTEINASE; QUININE; TICLOPIDINE; VON WILLEBRAND FACTOR;

EID: 0033920541     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.53.7.497     Document Type: Article
Times cited : (29)

References (36)
  • 1
    • 0002978048 scopus 로고
    • Hyaline thrombosis of the terminal arterioles and capillaries: A hitherto undescrihed disease
    • 1 Moschowitz E. Hyaline thrombosis of the terminal arterioles and capillaries: a hitherto undescrihed disease. Proceedings of the New York Pathological Society 1924;24:21-4.
    • (1924) Proceedings of the New York Pathological Society , vol.24 , pp. 21-24
    • Moschowitz, E.1
  • 2
    • 0028955158 scopus 로고
    • Late relapses successfully treated for thrombotic thrombocytopenic purpura
    • 2 Shumak KH, Rock GA, Nair RC, Members of the Canadian Apheresis Group. Late relapses successfully treated for thrombotic thrombocytopenic purpura. Ann Intern Med 1995;122:569-72.
    • (1995) Ann Intern Med , vol.122 , pp. 569-572
    • Shumak, K.H.1    Rock, G.A.2    Nair, R.C.3
  • 3
    • 0032055447 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura associated with ticlopidine
    • 3 Bennett CL, Weinberg PD, Rozenberg-Ben-Dror K, et al. Thrombotic thrombocytopenic purpura associated with ticlopidine. Ann Intern Med 1998;128:541-4.
    • (1998) Ann Intern Med , vol.128 , pp. 541-544
    • Bennett, C.L.1    Weinberg, P.D.2    Rozenberg-Ben-Dror, K.3
  • 4
    • 0031556859 scopus 로고    scopus 로고
    • Bartonella-like erythrocyte inclusions in thrombotic thrombocytopenic purpura
    • 4 Tarantolo ST, Landmark JD, Iwen PC, et al. Bartonella-like erythrocyte inclusions in thrombotic thrombocytopenic purpura. Lancat 1997;350;1602.
    • (1997) Lancet , vol.350 , pp. 1602
    • Tarantolo, S.T.1    Landmark, J.D.2    Iwen, P.C.3
  • 5
    • 0026527356 scopus 로고
    • Chronic relapsing thrombotic thrombocytopenic purpura in infants with large von Willebrand factor multimers during remission
    • 5 Chintagumpala MM, Hurwitz RL, Moake JL, et al. Chronic relapsing thrombotic thrombocytopenic purpura in infants with large von Willebrand factor multimers during remission. J Pediatr 1992;120:49-53.
    • (1992) J Pediatr , vol.120 , pp. 49-53
    • Chintagumpala, M.M.1    Hurwitz, R.L.2    Moake, J.L.3
  • 6
    • 84943439165 scopus 로고
    • Hazard of platelet transfusion in thrombotic thrombocytopenic purpura
    • 6 Harkness DR, Byrnes JJ, Lian EC-Y, et al. Hazard of platelet transfusion in thrombotic thrombocytopenic purpura. JAMA 1981;246:1931-3.
    • (1981) JAMA , vol.246 , pp. 1931-1933
    • Harkness, D.R.1    Byrnes, J.J.2    Lian, E.C.-Y.3
  • 7
    • 0021858462 scopus 로고
    • Immunohistochemistry of vascular lesion in thrombotic thrombocytopenic purpura, with special reference to factor VIII related antigen
    • 7 Asada Y, Sumiyoshi A, Hayashi T, et al. Immunohistochemistry of vascular lesion in thrombotic thrombocytopenic purpura, with special reference to factor VIII related antigen. Thromb Res 1985;38:469-79.
    • (1985) Thromb Res , vol.38 , pp. 469-479
    • Asada, Y.1    Sumiyoshi, A.2    Hayashi, T.3
  • 8
    • 0022852282 scopus 로고
    • Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation
    • 8 Moake JL, Turner NA, Stathopoulos NA, et al. Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation. J Clin Invest 1986;78:1456-61.
    • (1986) J Clin Invest , vol.78 , pp. 1456-1461
    • Moake, J.L.1    Turner, N.A.2    Stathopoulos, N.A.3
  • 9
    • 0023908222 scopus 로고
    • Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin
    • 9 Moake JL, Turner NA, Stathopoulos NA, et al. Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin. Blood 1988;71: 1366-74.
    • (1988) Blood , vol.71 , pp. 1366-1374
    • Moake, J.L.1    Turner, N.A.2    Stathopoulos, N.A.3
  • 10
    • 0023155614 scopus 로고
    • Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb IIIa
    • 10 Peterson DM, Stathopoulos NA, Giorgio TD, et al. Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb IIIa. Bood 1987;69:625-8.
    • (1987) Bood , vol.69 , pp. 625-628
    • Peterson, D.M.1    Stathopoulos, N.A.2    Giorgio, T.D.3
  • 11
    • 0028233149 scopus 로고
    • Solvent/ detergent-treated plasma suppresses shear-induced platelet aggregation and prevents episodes of thrombotic thrombocytopenic purpura
    • 11 Moake J, Chintagumpala M, Turner N, et al. Solvent/ detergent-treated plasma suppresses shear-induced platelet aggregation and prevents episodes of thrombotic thrombocytopenic purpura. Blood 1994;84:490-7.
    • (1994) Blood , vol.84 , pp. 490-497
    • Moake, J.1    Chintagumpala, M.2    Turner, N.3
  • 12
    • 0030690339 scopus 로고    scopus 로고
    • Von Willebrand factor mediates increased platelet retention in recurrent thrombotic thrombocytopenic purpura
    • 12 Karpman D, Lethagen S, Kristoffersson A-C, et al. Von Willebrand factor mediates increased platelet retention in recurrent thrombotic thrombocytopenic purpura. Thromb Haemost 1997;78:1456-62.
    • (1997) Thromb Haemost , vol.78 , pp. 1456-1462
    • Karpman, D.1    Lethagen, S.2    Kristoffersson, A.-C.3
  • 13
    • 0026001694 scopus 로고
    • The high molecular weight form of endotheliai cell von Willebrand factor is released by the regulated pathway
    • 13 Tsai H-M, Angel RL, Hatter VB, et al. The high molecular weight form of endotheliai cell von Willebrand factor is released by the regulated pathway. Br J Haematol 1991;79: 239-45.
    • (1991) Br J Haematol , vol.79 , pp. 239-245
    • Tsai, H.-M.1    Angel, R.L.2    Hatter, V.B.3
  • 14
    • 0030668512 scopus 로고    scopus 로고
    • The endothelial von Willebrand factor in venous occlusion blood
    • 14 O'Brien JR, Etherington MD. The endothelial von Willebrand factor in venous occlusion blood. Thromb Haemost 1997;78:1528-9.
    • (1997) Thromb Haemost , vol.78 , pp. 1528-1529
    • O'Brien, J.R.1    Etherington, M.D.2
  • 15
    • 0022517442 scopus 로고
    • Subunit composition of plasma von Willebrand factor
    • 15 Zimmerman TS, Dent JA, Ruggeri ZM, et al. Subunit composition of plasma von Willebrand factor. J Clin Invest 1986;77:947-51.
    • (1986) J Clin Invest , vol.77 , pp. 947-951
    • Zimmerman, T.S.1    Dent, J.A.2    Ruggeri, Z.M.3
  • 16
    • 0025895660 scopus 로고
    • Subunit composition of plasma von Willebrand factor multimers: Evidence for a non-proteolytic mechanism resulting in apparent increase in proteolytic fragments
    • 16 Tsai H-M, Angel RL, Susan II. Subunit composition of plasma von Willebrand factor multimers: evidence for a non-proteolytic mechanism resulting in apparent increase in proteolytic fragments. Thromb Res 1991;63:179-88.
    • (1991) Thromb Res , vol.63 , pp. 179-188
    • Tsai, H.-M.1    Angel, R.L.2    Susan, I.I.3
  • 17
    • 0026069774 scopus 로고
    • Heterogeneity of plasma von Willebrand factor multimers resulting form proteolysis of the constituent subunit
    • 17 Dent JA, Galbusera M, Ruggeri ZM. Heterogeneity of plasma von Willebrand factor multimers resulting form proteolysis of the constituent subunit. J Clin Invest 1991;88:774-82.
    • (1991) J Clin Invest , vol.88 , pp. 774-782
    • Dent, J.A.1    Galbusera, M.2    Ruggeri, Z.M.3
  • 18
    • 0001601210 scopus 로고
    • Plasma von Willebrand factor processing activity functions like a disulfide bond reductase: Reversible decrease of multimer size
    • 18 Phillips MD, Moake JL, Nolasco L, et al. Plasma von Willebrand factor processing activity functions like a disulfide bond reductase: reversible decrease of multimer size [abstract]. Thromb Haemost 1993;69:2342.
    • (1993) Thromb Haemost , vol.69 , pp. 2342
    • Phillips, M.D.1    Moake, J.L.2    Nolasco, L.3
  • 19
    • 0029925856 scopus 로고    scopus 로고
    • Partial purification of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis
    • 19 Furlan M, Robles R, Lämmle B. Partial purification of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis. Blood 1996;87:4223-34.
    • (1996) Blood , vol.87 , pp. 4223-4234
    • Furlan, M.1    Robles, R.2    Lämmle, B.3
  • 20
    • 0029878123 scopus 로고    scopus 로고
    • Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion
    • 20 Tsai H-M. Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion. Blood 1996;87:4235-44.
    • (1996) Blood , vol.87 , pp. 4235-4244
    • Tsai, H.-M.1
  • 21
    • 0028266474 scopus 로고
    • Shear stress enhances proteolysis of von Willebrand factor in normal plasma
    • 21 Tsai H-M, Susan II, Angel RL. Shear stress enhances proteolysis of von Willebrand factor in normal plasma. Blood 1994;83:2171-9.
    • (1994) Blood , vol.83 , pp. 2171-2179
    • Tsai, H.-M.1    Susan, I.I.2    Angel, R.L.3
  • 22
    • 0030973267 scopus 로고    scopus 로고
    • Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura
    • 22 Furlan M, Robles R, Solenthaler M, et al. Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura. Blood 1997;89:3097-103.
    • (1997) Blood , vol.89 , pp. 3097-3103
    • Furlan, M.1    Robles, R.2    Solenthaler, M.3
  • 23
    • 0032569884 scopus 로고    scopus 로고
    • Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome
    • 23 Furlan M, Robles R, Galbusera M, et al. Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. N Engl J Med 1998,339:1578-84.
    • (1998) N Engl J Med , vol.339 , pp. 1578-1584
    • Furlan, M.1    Robles, R.2    Galbusera, M.3
  • 24
    • 0032569840 scopus 로고    scopus 로고
    • Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura
    • 24 Tsai H-M, Lian EC-Y. Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura. N Engl J Med 1998;339:1585-94.
    • (1998) N Engl J Med , vol.339 , pp. 1585-1594
    • Tsai, H.-M.1    Lian, E.C.-Y.2
  • 25
    • 17944386474 scopus 로고    scopus 로고
    • Poor outcome in disseminated intravascular coagulation or thrombotic thrombocytopenic purpura patients with severe vascular endothelial cell injuries
    • 25 Wada H, Mori Y, Shimura M, et al. Poor outcome in disseminated intravascular coagulation or thrombotic thrombocytopenic purpura patients with severe vascular endothelial cell injuries. Am J Hematol 1998;58:189-94.
    • (1998) Am J Hematol , vol.58 , pp. 189-194
    • Wada, H.1    Mori, Y.2    Shimura, M.3
  • 26
    • 0028346831 scopus 로고
    • Plasma P-selectin is increased in thrombotic consumptive platelet disorders
    • 26 Chong BH, Murray B, Berndt MC, et al. Plasma P-selectin is increased in thrombotic consumptive platelet disorders. Blood 1994;83:1535-41.
    • (1994) Blood , vol.83 , pp. 1535-1541
    • Chong, B.H.1    Murray, B.2    Berndt, M.C.3
  • 27
    • 0027274863 scopus 로고
    • Soluble P-selectin is present in normal circulation and its plasma level is elevated in patients with thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome
    • 27 Katayama M, Handa M, Araki Y, et al. Soluble P-selectin is present in normal circulation and its plasma level is elevated in patients with thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome. Br J Haematol 1993;84:702-10.
    • (1993) Br J Haematol , vol.84 , pp. 702-710
    • Katayama, M.1    Handa, M.2    Araki, Y.3
  • 28
    • 0027281982 scopus 로고
    • Increased levels of vascular endothelial cell markers in thrombotic thrombocytopenic purpura
    • 28 Wada H, Kaneko T, Ohiwa M, et al. Increased levels of vascular endothelial cell markers in thrombotic thrombocytopenic purpura. Am J Hematol 1993;44:101-5.
    • (1993) Am J Hematol , vol.44 , pp. 101-105
    • Wada, H.1    Kaneko, T.2    Ohiwa, M.3
  • 29
    • 17344375843 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor (PAI-1) antigen levels in primary TTP and secondary TTP post-bone marrow transplantation
    • 29 Anthony MT, Zeigler ZR, Lister J, et al. Plasminogen activator inhibitor (PAI-1) antigen levels in primary TTP and secondary TTP post-bone marrow transplantation. Am J Hematol 1998;59:9-14.
    • (1998) Am J Hematol , vol.59 , pp. 9-14
    • Anthony, M.T.1    Zeigler, Z.R.2    Lister, J.3
  • 30
    • 0028843433 scopus 로고
    • Decreased plasma tissue factor pathway inhibitor levels in patients with thrombotic thrombocytopenic purpura
    • 30 Kobayashi M, Wada H, Wakita Y, et al. Decreased plasma tissue factor pathway inhibitor levels in patients with thrombotic thrombocytopenic purpura. Thromb Haemost 1995;73:10-4.
    • (1995) Thromb Haemost , vol.73 , pp. 10-14
    • Kobayashi, M.1    Wada, H.2    Wakita, Y.3
  • 31
    • 0029868454 scopus 로고    scopus 로고
    • Plasma from patients with idiopathic and human immunodeficiency virus-associated thrombotic thrombocytopenic purpura induces apoptosis in microvascular endothelial cell lines
    • 31 Laurence J, Mitra D, Steiner M, et al. Plasma from patients with idiopathic and human immunodeficiency virus-associated thrombotic thrombocytopenic purpura induces apoptosis in microvascular endothelial cell lines. Blood 1996;87:3245-54.
    • (1996) Blood , vol.87 , pp. 3245-3254
    • Laurence, J.1    Mitra, D.2    Steiner, M.3
  • 32
    • 0031050433 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura and sporadic hemolytic-uremic syndrome plasmas induce apoptosis in restricted lineages of human microvascular endothelial cells
    • 32 Mitra D, Jaffe EA, Weksler B, et al. Thrombotic thrombocytopenic purpura and sporadic hemolytic-uremic syndrome plasmas induce apoptosis in restricted lineages of human microvascular endothelial cells. Blood 1997;89:1224-34.
    • (1997) Blood , vol.89 , pp. 1224-1234
    • Mitra, D.1    Jaffe, E.A.2    Weksler, B.3
  • 33
    • 0031942987 scopus 로고    scopus 로고
    • Increased von Willebrand factor binding to platelets in single episode and recurrent types of thrombotic thrombocytopenic purpura
    • 33 Chow TW, Turner NA, Chintagumpala M, et al. Increased von Willebrand factor binding to platelets in single episode and recurrent types of thrombotic thrombocytopenic purpura. Am J Hematol 1998;57:293-302.
    • (1998) Am J Hematol , vol.57 , pp. 293-302
    • Chow, T.W.1    Turner, N.A.2    Chintagumpala, M.3
  • 34
    • 0024734977 scopus 로고
    • Abnormalities of von Willebrand factor multimers in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome
    • 34 Moake JL, McPherson PD. Abnormalities of von Willebrand factor multimers in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. Am J Med 1989;87:3-9N.
    • (1989) Am J Med , vol.87
    • Moake, J.L.1    McPherson, P.D.2
  • 35
    • 0032918258 scopus 로고    scopus 로고
    • Recovery and half-life of von Willebrand factor-cleaving protease after plasma therapy in patients with thrombotic thrombocytopenic purpura
    • 35 Furlan M, Robles R, Morselli B, et al. Recovery and half-life of von Willebrand factor-cleaving protease after plasma therapy in patients with thrombotic thrombocytopenic purpura. Thromb Haemost 1999;81:8-13.
    • (1999) Thromb Haemost , vol.81 , pp. 8-13
    • Furlan, M.1    Robles, R.2    Morselli, B.3
  • 36
    • 0033151555 scopus 로고    scopus 로고
    • Von Willebrand factor proteolysis is deficient in classic, but not in bone marrow transplantation-associated, thrombotic thrombocytopenic purpura
    • 36 Van der Plas RM, Schiphorst ME, Huizinga EG, et al. von Willebrand factor proteolysis is deficient in classic, but not in bone marrow transplantation-associated, thrombotic thrombocytopenic purpura. Blood 1999;93:3798-802.
    • (1999) Blood , vol.93 , pp. 3798-3802
    • Van Der Plas, R.M.1    Schiphorst, M.E.2    Huizinga, E.G.3


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