Correlation between vasoconstrictor roles and mRNA expression of α 1-adrenoceptor subtypes in blood vessels of genetically engineered mice

British Journal of Pharmacology

Volumn 146, Issue 3, 2005, Pages 456-466

  Hosoda, Chihiro ^a,e   Tanoue, Akito ^a   Shibano, Mari ^b   Tanaka, Yoshio ^b   Hiroyama, Masami ^a   Koshimizu, Taka Aki ^c   Cotecchia, Susanna ^d   Kitamura, Tadaichi ^e   Tsujimoto, Gozoh ^c   Koike, Katsuo ^b  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b TOHO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d Faculte de Medecine   (Switzerland)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

1 Adrenoceptor subtype; 1B knockout mouse; 1BD double knockout mouse; 1D knockout mouse; Mouse mesenteric artery; Mouse thoracic aorta; Noradrenaline; Real time PCR; Vasoconstriction

Indexed keywords

8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; MESSENGER RNA; NORADRENALIN BITARTRATE; PRAZOSIN; PROTEIN SUBUNIT; SILODOSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD VESSEL; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; DRUG RESPONSE; GENETIC ENGINEERING; MESENTERIC ARTERY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; THORACIC AORTA; VASOCONSTRICTION; WILD TYPE;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; AORTA, THORACIC; GENE EXPRESSION REGULATION; INDOLES; MALE; MESENTERIC ARTERIES; MICE; MICE, KNOCKOUT; NOREPINEPHRINE; PIPERAZINES; PRAZOSIN; RECEPTORS, ADRENERGIC, ALPHA-1; RNA, MESSENGER; VASOCONSTRICTION;

EID: 27144504528     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706325     Document Type: Article

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