Implication of Pkc1p protein kinase C in sustaining Cln2p level and polarized bud growth in response to calcium signaling in Saccharomyces cerevisiae

Journal of Cell Science

Volumn 118, Issue 18, 2005, Pages 4219-4229

  Mizunuma, Masaki ^a   Hirata, Dai ^a   Miyakawa, Tokichi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Calcium; Cln2p; Mpk1p; Pkc1p; Saccharomyces cerevisiae

Indexed keywords

CALCIUM ION; CYCLIN 2; CYCLIN G1; F ACTIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE C1; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CALCIUM SIGNALING; CELL CYCLE; CELL PROLIFERATION; CELL WALL; CONTROLLED STUDY; ENZYME ACTIVATION; EUKARYOTE; GENETIC SCREENING; GROWTH REGULATION; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPIC VARIATION; POLARIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; TRANSCRIPTION REGULATION; UPREGULATION;

ACTINS; ALLELES; AMINO ACID SEQUENCE; BASE SEQUENCE; CALCIUM; CALCIUM SIGNALING; CELL WALL; CYCLINS; ENZYME ACTIVATION; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN KINASE C; RHO GTP-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UP-REGULATION;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 27144498201     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02535     Document Type: Article

References (37)

1. Adams, A. E. M. and Pringle, J. R. (1991). Staining of actin with fluorochrome-conjugated phalloidin. Methods Enzymol. 194, 729-731.
2. Baetz, K., Moffat, J., Haynes, J., Chang, M. and Andrews, B. (2001). Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4. Mol. Cell. Biol. 21, 6515-6528.
3. Bi, E. and Pringle, J. R. (1996). ZDS1 and ZDS2, genes whose products may regulate Cdc42p in Saccharomyces cerevisiae. Mol. Cell. Biol. 16, 5264-5275.
4. 2 cyclins. EMBO J. 12, 3417-3426.
5. Davenport, K. R., Sohaskey, M., Kamada, Y., Levin, D. E. and Gustin, M. C. (1995). A second osmosensing signal transduction pathway in yeast. Hypotonic shock activates the PKC1 protein kinase-regulated cell integrity pathway. J. Biol. Chem. 50, 30157-30161.
6. Delley, P. A. and Hall, M. N. (1999). Cell wall stress depolarizes cell growth via hyperactivation of RHO1. J. Cell Biol. 147, 163-174.
7. Dodou, E. and Treisman, R. (1997). The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway. Mol. Cell. Biol. 17, 1848-1859.
8. Drubin, D. G. and Nelson, W. J. (1996). Origins of cell polarity. Cell 84, 335-344.
9. Gray, J. V., Ogas, J. P., Kamada, Y., Stone, M., Levin, D. E. and Herskowitz, I. (1997). A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator. EMBO J. 16, 4924-4937.
10. Gustin, M. C., Albertyn, J., Alexander, M. and Davenport, K. (1998). MAP kinase pathways in the yeast Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 62, 1264-1300.
11. Heinisch, J. J., Lorberg, A., Schmitz, H. P. and Jacoby, J. J. (1999). The protein kinase C-mediated MAP kinase pathway involved in the maintenance of cellular integrity in Saccharomyces cerevisiae. Mol. Microbiol. 32, 671-680.
12. Helliwell, S. B., Schmidt, A., Ohya, Y. and Hall, M. N. (1998). The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Curr. Biol. 8, 1211-1214.
13. Igual, J. C., Johnson, A. L. and Johnston, L. H. (1996). Coordinated regulation of gene expression by the cell cycle transcription factor SWI4 and the protein kinase C MAP kinase pathway for yeast cell integrity. EMBO J. 15, 5001-5013.
14. Kamada, Y., Sung Jung, U., Piotrowski, J. and Levin, D. E. (1995). The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Genes Dev. 9, 1559-1571.
15. Kamada, Y., Qadota, H., Python, C. P., Anraku, Y. and Levin, D. E. (1996). Activation of yeast protein kinase C by Rho1 GTPase. J. Biol. Chem. 271, 9193-9196.
16. 1 cyclin Cln2 induced by CDK-dependent phosphorylation. Science 271, 1597-1601.
17. Levin, D. E. and Bartlett-Heubusch, E. (1992). Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect J. Cell Biol. 116, 1221-1229.
18. Levin, D. E. and Errede, B. (1995). The proliferation of MAP kinase signaling pathways in yeast. Curr. Opin. Cell Biol. 7, 197-202.
19. Levin, D. E., Fields, F. P., Kunisawa, R., Bishop, J. M. and Thorner, J. (1990). A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Cell 62, 213-224.
20. Lew, D. J. and Reed, S. I. (1993). Morphogenesis in the yeast cell cycle: Regulation by Cdc28 and cyclins. J. Cell Biol. 120, 1305-1320.
21. Lew, D. J. and Reed, S. I. (1995). A cell cycle checkpoint monitors cell morphogenesis in budding yeast. J. Cell Biol. 129, 739-749.
22. Ma, X. J., Lu, Q. and Grunstein, M. (1996). A search for proteins that interact genetically with histone H3 and H4 amino termini uncovers novel regulators of the Swe1 kinase in Saccharomyces cerevisiae. Genes Dev. 10, 1327-1340.
23. Madden, K., Sheu, Y. J., Baetz, K., Andrews, B. and Snyder, M. (1997). SBF cell cycle regulator as a target of the yeast PKC-MAP kinase pathway. Science 275, 1781-1784.
24. Marini, N. J., Meldrum, E., Buehrer, B., Hubberstey, A. V., Stone, D. E., Traynor-Kaplan, A. and Reed, S. I. (1996). A pathway in the yeast cell division cycle linking protein kinase C (Pkc1) to activation of Cdc28 at START. EMBO J. 15, 3040-3052.
25. Mazzoni, C., Zarzov, P., Rambourg, A. and Mann, C. (1993). The Slt2 (Mpk1) MAP kinase homolog is involved in polarized cell growth in Saccharomyces cerevisiae. J. Cell Biol. 123, 1821-1833.
26. McMillan, J. N., Sia, R. A. and Lew, D. J. (1998). A morphogenesis checkpoint monitors the actin cytoskeleton in yeast. J. Cell Biol. 142, 1487-1499.
27. Mizunuma, M., Hirata, D., Miyahara, K., Tsuchiya, E. and Miyakawa, T. (1998). Role of calcineurin and Mpk1 in regulating the onset of mitosis in budding yeast. Nature 392, 303-306.
28. 2+ in budding yeast. EMBO J. 20, 1074-1085.
29. 1 cell-cycle regulation in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 101, 6086-6091.
30. Nonaka, H., Tanaka, K., Hirano, H., Fujiwara, T., Kohno, H., Umikawa, M., Mino, A. and Takai, Y. (1995). A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae. EMBO J. 14, 5931-5938.
31. Paravicini, G., Cooper, M., Friedli, L., Smith, D. J., Carpentier, J. L., Klig, L. S. and Payton, M. A. (1992). The osmotic integrity of the yeast cell requires a functional PKC1 gene product. Mol. Cell. Biol. 12, 4896-4905.
32. Pruyne, D. and Bretscher, A. (2000). Polarization of cell growth in yeast. J. Cell Sci. 113, 571-585.
33. Saka, A., Abe, M., Okano, H., Minemura, M., Qadota, H., Utsugi, T., Mino, A., Tanaka, K., Takai, Y. and Ohya, Y. (2001). Complementing yeast rho1 mutation groups with distinct functional defects. J. Biol. Chem. 276, 46165-46171.
34. Sia, R. A., Bardes, E. S. and Lew, D. J. (1998). Control of Swe1p degradation by the morphogenesis checkpoint. EMBO J. 17, 6678-6688.
35. Yoshida, S., Ikeda, E., Uno, I. and Mitsuzawa, H. (1992). Characterization of a staurosporine- and temperature-sensitive mutant, stt1, of Saccharomyces cerevisiae: STT1 is allelic to PKC1. Mol. Gen. Genet. 231, 337-344.
36. Yu, Y., Jiang, Y. W., Wellinger, R. J., Carlson, K., Roberts, J. M. and Stillman, D. J. (1996). Mutation in the homologous ZDS1 and ZDS2 genes affect cell cycle progression. Mol. Cell. Biol. 16, 5254-5263.
37. Zarzov, P., Mazzoni, C. and Mann, C. (1996). The Slt2 (Mpk1) MAP kinase is activated during periods of polarized cell growth in yeast. EMBO J. 15, 83-91.