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Volumn 99, Issue 11, 2005, Pages 1403-1412

Pathophysiology of exercise dyspnea in healthy subjects and in patients with chronic obstructive pulmonary disease (COPD)

Author keywords

Arterial blood gases; Cardiac function; Dyspnea; Exercise; Hyperinflation; Respiratory muscles

Indexed keywords

ARTERIAL GAS; ARTICLE; BREATHING MECHANICS; BREATHING MUSCLE; CARBON DIOXIDE TENSION; CHRONIC OBSTRUCTIVE LUNG DISEASE; DYSPNEA; EXERCISE; HEART OUTPUT; HUMAN; HYPERCAPNIA; HYPOXIA; LUNG VENTILATION; LUNG VOLUME; MUSCLE FATIGUE; MUSCLE WEAKNESS; PATHOPHYSIOLOGY; PERCEPTION; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; SCORING SYSTEM; SYMPTOM; THORAX PRESSURE;

EID: 27144493225     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2005.03.005     Document Type: Article
Times cited : (31)

References (79)
  • 1
    • 0032943991 scopus 로고    scopus 로고
    • Mechanisms, assessment, and management: A consensus Statement
    • American Thoracic Society Dyspnea
    • American Thoracic Society Dyspnea Mechanisms, assessment, and management: A consensus Statement Am J Respir Crit Care Med 159 1999 321-340
    • (1999) Am. J. Respir. Crit. Care Med. , vol.159 , pp. 321-340
  • 2
    • 9844227359 scopus 로고    scopus 로고
    • Pulmonary Rehabilitation, Joint ACCP/AACVPR. Evidence-Based Guidelines
    • ACCP/AACVPR
    • ACCP/AACVPR Pulmonary Rehabilitation, Joint ACCP/AACVPR. Evidence-Based Guidelines Chest 112 1997 1363-1396
    • (1997) Chest , vol.112 , pp. 1363-1396
  • 3
    • 0031027165 scopus 로고    scopus 로고
    • Qualitative aspects of exertional breathlessness in chronic airflow limitation
    • D.E. O'Donnell J.C. Bertley L.K. Chau et al. Qualitative aspects of exertional breathlessness in chronic airflow limitation Am J Respir Crit Care Med 115 1997 109-115
    • (1997) Am. J. Respir. Crit. Care Med. , vol.115 , pp. 109-115
    • O'Donnell, D.E.1    Bertley, J.C.2    Chau, L.K.3
  • 4
    • 0022542573 scopus 로고
    • Breathlessness during exercise with and without resistive loading
    • A. El-Manshawi K.J. Killian E. Summers et al. Breathlessness during exercise with and without resistive loading J Appl Physiol 61 1986 896-905
    • (1986) J. Appl. Physiol. , vol.61 , pp. 896-905
    • El-Manshawi, A.1    Killian, K.J.2    Summers, E.3
  • 5
    • 0023887546 scopus 로고
    • Inspiratory muscles during exercise: A problem of supply and demand
    • P. Leblanc E. Summers M.D. Inman et al. Inspiratory muscles during exercise: A problem of supply and demand J Appl Physiol 64 1988 2482-2489
    • (1988) J. Appl. Physiol. , vol.64 , pp. 2482-2489
    • Leblanc, P.1    Summers, E.2    Inman, M.D.3
  • 6
    • 0023685510 scopus 로고
    • Effect of continuous positive airway pressure on respiratory sensation in patients with chronic obstructive pulmonary disease during submaximal exercise
    • D.E. O'Donnell R. Sanij G. Giesbrecht et al. Effect of continuous positive airway pressure on respiratory sensation in patients with chronic obstructive pulmonary disease during submaximal exercise Am Rev Respir Dis 138 1988 1185-1191
    • (1988) Am. Rev. Respir. Dis. , vol.138 , pp. 1185-1191
    • O'Donnell, D.E.1    Sanij, R.2    Giesbrecht, G.3
  • 7
    • 0024263736 scopus 로고
    • Improvement in exercise endurance in patients with chronic airflow limitation using continuous positive airway pressure
    • D.E. O'Donnell R. Sanij M. Younes Improvement in exercise endurance in patients with chronic airflow limitation using continuous positive airway pressure Am Rev Respir Dis 138 1988 1510-1514
    • (1988) Am. Rev. Respir. Dis. , vol.138 , pp. 1510-1514
    • O'Donnell, D.E.1    Sanij, R.2    Younes, M.3
  • 8
    • 0029019866 scopus 로고
    • Contribution of diaphragmatic power output to exercise-induced diaphragm fatigue
    • M.A. Babcock D.F. Pegelow S.R. McLaran et al. Contribution of diaphragmatic power output to exercise-induced diaphragm fatigue J Appl Physiol 78 1995 1710-1719
    • (1995) J. Appl. Physiol. , vol.78 , pp. 1710-1719
    • Babcock, M.A.1    Pegelow, D.F.2    McLaran, S.R.3
  • 9
    • 0012146916 scopus 로고
    • Respiratory muscle action inferred from rib cage and abdominal V-P partitioning
    • A. Grimby M. Goldman J. Mead Respiratory muscle action inferred from rib cage and abdominal V-P partitioning J Appl Physiol 41 1976 739-751
    • (1976) J. Appl. Physiol. , vol.41 , pp. 739-751
    • Grimby, A.1    Goldman, M.2    Mead, J.3
  • 10
    • 0030801343 scopus 로고    scopus 로고
    • Respiratory effort Sensation during exercise with induced expiratory flow limitation in healthy humans
    • B. Kayser P. Sliwinski S. Yan et al. Respiratory effort Sensation during exercise with induced expiratory flow limitation in healthy humans J Appl Physiol 83 1997 936-947
    • (1997) J. Appl. Physiol. , vol.83 , pp. 936-947
    • Kayser, B.1    Sliwinski, P.2    Yan, S.3
  • 11
    • 0024214945 scopus 로고
    • Respiratory sensation and pattern of respiratory muscle activation during diaphragm fatigue
    • M.E. Ward D.G. Eidelman D.G. Stubbing et al. Respiratory sensation and pattern of respiratory muscle activation during diaphragm fatigue J Appl Physiol 65 1988 2181-2189
    • (1988) J. Appl. Physiol. , vol.65 , pp. 2181-2189
    • Ward, M.E.1    Eidelman, D.G.2    Stubbing, D.G.3
  • 12
    • 0029872052 scopus 로고    scopus 로고
    • Influence of global inspiratory muscle fatigue on breathing during exercise
    • P. Sliwinski S. Yan A.P. Gauthier et al. Influence of global inspiratory muscle fatigue on breathing during exercise J Appl Physiol 80 1996 1270-1278
    • (1996) J. Appl. Physiol. , vol.80 , pp. 1270-1278
    • Sliwinski, P.1    Yan, S.2    Gauthier, A.P.3
  • 13
    • 0028916049 scopus 로고
    • Pressure support reduces inspiratory effort and dyspnea during exercise in chronic airflow obstruction
    • F. Maltais H. Reissman S.B. Gottfried Pressure support reduces inspiratory effort and dyspnea during exercise in chronic airflow obstruction Am J Respir Crit Care Med 151 1995 1027-1033
    • (1995) Am. J. Respir. Crit. Care Med. , vol.151 , pp. 1027-1033
    • Maltais, F.1    Reissman, H.2    Gottfried, S.B.3
  • 14
    • 0025281622 scopus 로고
    • Factors influencing ventilatory muscle recruitment in patients with chronic airflow obstruction
    • F.J. Martinez J.I. Couser B.R. Celli Factors influencing ventilatory muscle recruitment in patients with chronic airflow obstruction Am Rev Respir Dis 142 1990 276-282
    • (1990) Am. Rev. Respir. Dis. , vol.142 , pp. 276-282
    • Martinez, F.J.1    Couser, J.I.2    Celli, B.R.3
  • 15
    • 0027367581 scopus 로고
    • The ventilatory response to arm elevation of patients with chronic obstructive pulmonary disease
    • T.E. Dolmage L. Maestro M.A. Avendano et al. The ventilatory response to arm elevation of patients with chronic obstructive pulmonary disease Chest 104 1993 1097-1100
    • (1993) Chest , vol.104 , pp. 1097-1100
    • Dolmage, T.E.1    Maestro, L.2    Avendano, M.A.3
  • 16
    • 0023688498 scopus 로고
    • Effect of unsupported arm exercise on ventilatory muscle recruitment in patients with severe chronic airflow obstruction
    • G. Criner B.R. Celli Effect of unsupported arm exercise on ventilatory muscle recruitment in patients with severe chronic airflow obstruction Am Rev Respir Dis 138 1988 856-861
    • (1988) Am. Rev. Respir. Dis. , vol.138 , pp. 856-861
    • Criner, G.1    Celli, B.R.2
  • 17
    • 0022642218 scopus 로고
    • Dyssynchronous breathing during arm but not leg exercise in patients with chronic airflow obstruction
    • B. Celli J. Rassulo B.J. Make Dyssynchronous breathing during arm but not leg exercise in patients with chronic airflow obstruction N Engl J Med 314 1986 1485-1490
    • (1986) N. Engl. J. Med. , vol.314 , pp. 1485-1490
    • Celli, B.1    Rassulo, J.2    Make, B.J.3
  • 18
    • 0028892391 scopus 로고
    • Muscle strength, symptom intensity, and exercise capacity in patients with cardiorespiratory disorders
    • A.L. Hamilton K.J. Killian E. Summers et al. Muscle strength, symptom intensity, and exercise capacity in patients with cardiorespiratory disorders Am J Respir Crit Care Med 152 1995 2021-2031
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , pp. 2021-2031
    • Hamilton, A.L.1    Killian, K.J.2    Summers, E.3
  • 19
    • 0025326531 scopus 로고
    • Respiratory muscle fatigue. Report of the respiratory muscle fatigue workshop group
    • NHLB Workshop
    • NHLB Workshop Respiratory muscle fatigue. Report of the respiratory muscle fatigue workshop group Am Rev Respir Dis 142 1990 474-480
    • (1990) Am. Rev. Respir. Dis. , vol.142 , pp. 474-480
  • 20
    • 0023019083 scopus 로고
    • The relation of inspiratory effort sensation to fatiguing patterns of the diaphragm
    • T.D. Bradley D.A. Chartrand J.W. Fitting et al. The relation of inspiratory effort sensation to fatiguing patterns of the diaphragm Am Rev Respir Dis 134 1986 1119-1124
    • (1986) Am. Rev. Respir. Dis. , vol.134 , pp. 1119-1124
    • Bradley, T.D.1    Chartrand, D.A.2    Fitting, J.W.3
  • 21
    • 0034012128 scopus 로고    scopus 로고
    • Quadriceps fatigue after cycle exercise in patients with chronic obstructive pulmonary disease
    • M.J. Mador T.J. Kufel L. Pineda Quadriceps fatigue after cycle exercise in patients with chronic obstructive pulmonary disease Am J Respir Crit Care Med 161 2000 447-453
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 447-453
    • Mador, M.J.1    Kufel, T.J.2    Pineda, L.3
  • 22
    • 0033983246 scopus 로고    scopus 로고
    • Diaphragmatic fatigue and high-intensity exercise in patients with chronic obstructive pulmonary disease
    • M.J. Mador T.J. Kufel L.A. Pineda et al. Diaphragmatic fatigue and high-intensity exercise in patients with chronic obstructive pulmonary disease Am J Respir Crit Care Med 161 2000 118-123
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 118-123
    • Mador, M.J.1    Kufel, T.J.2    Pineda, L.A.3
  • 23
    • 0029082981 scopus 로고
    • Exhaustive treadmill exercise does not reduce twitch transdiaphragmatic pressure in patients with COPD
    • M.I. Polkey D. Kyroussis S.E. Keilty et al. Exhaustive treadmill exercise does not reduce twitch transdiaphragmatic pressure in patients with COPD Am J Respir Crit Care Med 152 3 1995 959-964
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , Issue.3 , pp. 959-964
    • Polkey, M.I.1    Kyroussis, D.2    Keilty, S.E.3
  • 24
    • 0034948751 scopus 로고    scopus 로고
    • Diaphragm activation during exercise in chronic obstructive pulmonary disease
    • C. Sinderby J. Spahija J. Beck et al. Diaphragm activation during exercise in chronic obstructive pulmonary disease Am J Respir Crit Care Med 163 2001 1637-1641
    • (2001) Am. J. Respir. Crit. Care Med. , vol.163 , pp. 1637-1641
    • Sinderby, C.1    Spahija, J.2    Beck, J.3
  • 25
    • 0030879657 scopus 로고    scopus 로고
    • Human respiratory muscle actions and control during exercise
    • A. Aliverti S.J. Cala R. Duranti et al. Human respiratory muscle actions and control during exercise J Appl Physiol 83 1997 1256-1269
    • (1997) J. Appl. Physiol. , vol.83 , pp. 1256-1269
    • Aliverti, A.1    Cala, S.J.2    Duranti, R.3
  • 26
    • 0032861447 scopus 로고    scopus 로고
    • Chest wall kinematics and respiratory muscle action in walking healthy humans
    • A. Sanna F. Bertoli G. Misuri et al. Chest wall kinematics and respiratory muscle action in walking healthy humans J Appl Physiol 87 1999 938-946
    • (1999) J. Appl. Physiol. , vol.87 , pp. 938-946
    • Sanna, A.1    Bertoli, F.2    Misuri, G.3
  • 27
    • 0036082035 scopus 로고    scopus 로고
    • Respiratory muscle dynamics and control during exercise with externally imposed expiratory flow limitation
    • A. Aliverti I. Iandelli R. Duranti et al. Respiratory muscle dynamics and control during exercise with externally imposed expiratory flow limitation J Appl Physiol 92 5 2002 1953-1963
    • (2002) J. Appl. Physiol. , vol.92 , Issue.5 , pp. 1953-1963
    • Aliverti, A.1    Iandelli, I.2    Duranti, R.3
  • 28
    • 0036085585 scopus 로고    scopus 로고
    • Determinants of exercise performance in normal men with externally imposed expiratory flow limitation
    • I. Iandelli A. Aliverti B. Kayser et al. Determinants of exercise performance in normal men with externally imposed expiratory flow limitation J Appl Physiol 92 5 2002 1943-1952
    • (2002) J. Appl. Physiol. , vol.92 , Issue.5 , pp. 1943-1952
    • Iandelli, I.1    Aliverti, A.2    Kayser, B.3
  • 29
    • 0015042496 scopus 로고
    • Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease
    • W.A. Potter S. Olafsson R.E. Hyatt Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease J Clin Invest 50 1971 910-918
    • (1971) J. Clin. Invest. , vol.50 , pp. 910-918
    • Potter, W.A.1    Olafsson, S.2    Hyatt, R.E.3
  • 30
    • 0030971611 scopus 로고    scopus 로고
    • Lung-volume reduction improves dyspnea, dynamic hyperinflation, and respiratory muscle function
    • F.J. Martinez M.M. de Oca R.I. Whyte et al. Lung-volume reduction improves dyspnea, dynamic hyperinflation, and respiratory muscle function Am J Respir Crit Care Med 155 1997 1984-1990
    • (1997) Am. J. Respir. Crit. Care Med. , vol.155 , pp. 1984-1990
    • Martinez, F.J.1    de Oca, M.M.2    Whyte, R.I.3
  • 31
    • 0021368195 scopus 로고
    • Chest wall mechanics during exercise in patients with severe chronic airflow obstruction
    • D.S. Dodd T. Brancatisano L.A. Engel Chest wall mechanics during exercise in patients with severe chronic airflow obstruction Am Rev Respir Dis 129 1984 33-38
    • (1984) Am. Rev. Respir. Dis. , vol.129 , pp. 33-38
    • Dodd, D.S.1    Brancatisano, T.2    Engel, L.A.3
  • 32
    • 0015540819 scopus 로고
    • Ventilatory levels and chest wall mechanics during exercise in obstructive lung disease
    • G. Grimby B. Elgefors H. Oxhoj Ventilatory levels and chest wall mechanics during exercise in obstructive lung disease Scand J Resp Dis 54 1973 45-52
    • (1973) Scand. J. Resp. Dis. , vol.54 , pp. 45-52
    • Grimby, G.1    Elgefors, B.2    Oxhoj, H.3
  • 33
    • 10544255731 scopus 로고    scopus 로고
    • Respiratory muscle and cardiopulmonary function during exercise in very severe COPD
    • M. Montes de Oca J. Rassulo B.R. Celli Respiratory muscle and cardiopulmonary function during exercise in very severe COPD Am J Respir Crit Care Med 154 1996 284-289
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154 , pp. 284-289
    • Montes de Oca, M.1    Rassulo, J.2    Celli, B.R.3
  • 34
    • 24944567030 scopus 로고
    • Respiratory muscle activation during exercise in chronic obstructive pulmonary disease
    • Jones Killian Boehringer Ingelheim editors. The Campbell symposium Hamilton, Ontario, Canada
    • N. Pride Respiratory muscle activation during exercise in chronic obstructive pulmonary disease In: Jones Killian Boehringer Ingelheim editors. Breathlessness 1992 The Campbell symposium Hamilton, Ontario, Canada 52-56
    • (1992) Breathlessness , pp. 52-56
    • Pride, N.1
  • 35
    • 0030012048 scopus 로고    scopus 로고
    • Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease
    • M.J. Belman W.C. Botnick J.W. Shin Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease Am J Respir Crit Care Med 153 1996 967-975
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 967-975
    • Belman, M.J.1    Botnick, W.C.2    Shin, J.W.3
  • 36
    • 0027358977 scopus 로고
    • Exertional breathlessness in patients with chronic airflow limitation: The role of lung hyperinflation
    • D.E. O'Donnell K.A. Webb Exertional breathlessness in patients with chronic airflow limitation: The role of lung hyperinflation Am Rev Respir Dis 148 1993 1351-1357
    • (1993) Am. Rev. Respir. Dis. , vol.148 , pp. 1351-1357
    • O'Donnell, D.E.1    Webb, K.A.2
  • 37
    • 0028041444 scopus 로고
    • Breathlessness in patients with chronic airflow limitation
    • D.E. O'Donnell Breathlessness in patients with chronic airflow limitation Chest 106 1994 904-912
    • (1994) Chest , vol.106 , pp. 904-912
    • O'Donnell, D.E.1
  • 38
    • 0030479467 scopus 로고    scopus 로고
    • Relationship between chronic dyspnea and expiratory flow limitation in patients with chronic obstructive pulmonary disease
    • L. Eltayara M.R. Becklake C.A. Volta et al. Relationship between chronic dyspnea and expiratory flow limitation in patients with chronic obstructive pulmonary disease Am J Respir Crit Care Med 154 1996 1726-1734
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154 , pp. 1726-1734
    • Eltayara, L.1    Becklake, M.R.2    Volta, C.A.3
  • 39
    • 0027174211 scopus 로고
    • Expiratory flow limitation and regulation of end-expiratory lung volume during exercise
    • R. Pellegrino V. Brusasco J.R. Rodarte et al. Expiratory flow limitation and regulation of end-expiratory lung volume during exercise J Appl Physiol 74 5 1993 2552-2558
    • (1993) J. Appl. Physiol. , vol.74 , Issue.5 , pp. 2552-2558
    • Pellegrino, R.1    Brusasco, V.2    Rodarte, J.R.3
  • 40
    • 0030906146 scopus 로고    scopus 로고
    • Detection of expiratory flow limitation during exercise in COPD patients
    • N.G. Koulouris I. Dimopoulou P. Valta et al. Detection of expiratory flow limitation during exercise in COPD patients J Appl Physiol 82 3 1997 723-731
    • (1997) J. Appl. Physiol. , vol.82 , Issue.3 , pp. 723-731
    • Koulouris, N.G.1    Dimopoulou, I.2    Valta, P.3
  • 41
    • 0026025498 scopus 로고
    • Effect of mild to moderate airflow limitation on exercise capacity
    • T.G. Babb B. Viggiano B. Hurley et al. Effect of mild to moderate airflow limitation on exercise capacity J Appl Physiol 70 1991 223-230
    • (1991) J. Appl. Physiol. , vol.70 , pp. 223-230
    • Babb, T.G.1    Viggiano, B.2    Hurley, B.3
  • 42
    • 0025732728 scopus 로고
    • Flow limitation and regulation of functional residual capacity during exercise in a physically active aging population
    • B.D. Johnson W.G. Reddan D.F. Pegelow et al. Flow limitation and regulation of functional residual capacity during exercise in a physically active aging population Am Rev Respir Dis 143 1991 960-967
    • (1991) Am. Rev. Respir. Dis. , vol.143 , pp. 960-967
    • Johnson, B.D.1    Reddan, W.G.2    Pegelow, D.F.3
  • 43
    • 0018964725 scopus 로고
    • Pulmonary mechanics during exercise in subjects with chronic airflow limitation
    • D.G. Stubbing L.D. Pengelly J.L.C. Morse et al. Pulmonary mechanics during exercise in subjects with chronic airflow limitation J Appl Physiol 49 1980 511-515
    • (1980) J. Appl. Physiol. , vol.49 , pp. 511-515
    • Stubbing, D.G.1    Pengelly, L.D.2    Morse, J.L.C.3
  • 44
    • 0035446990 scopus 로고    scopus 로고
    • Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease
    • D.E. O'Donnell S.M. Revill A.K. Webb Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease Am J Respir Crit Care Med 164 2001 770-777
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , pp. 770-777
    • O'Donnell, D.E.1    Revill, S.M.2    Webb, A.K.3
  • 45
    • 0030015340 scopus 로고    scopus 로고
    • Breathing pattern and carbon dioxide retention in severe chronic obstructive pulmonary disease
    • M. Gorini G. Misuri A. Corrado et al. Breathing pattern and carbon dioxide retention in severe chronic obstructive pulmonary disease Thorax 51 1996 677-683
    • (1996) Thorax , vol.51 , pp. 677-683
    • Gorini, M.1    Misuri, G.2    Corrado, A.3
  • 46
    • 0001587452 scopus 로고
    • Corollary discharges: Motor commands and perception
    • J.M. Brookhart V.B. Mountcastle editors. American Physiological Society Bethesda, MD
    • D.I. McCluskey Corollary discharges: Motor commands and perception In: J.M. Brookhart V.B. Mountcastle editors. The Nervous System. Handbook Of Physiology Section 1, Volume 2, Part 2 1981 American Physiological Society Bethesda, MD 1415-1447
    • (1981) The Nervous System. Handbook Of Physiology Section 1 , vol.2 , Issue.PART 2 , pp. 1415-1447
    • McCluskey, D.I.1
  • 47
    • 0032906207 scopus 로고    scopus 로고
    • External thoracic restriction, respiratory sensation, and ventilation during exercise in men
    • E.R. Harty D.R. Corfield R.M. Schwartzstein et al. External thoracic restriction, respiratory sensation, and ventilation during exercise in men J Appl Physiol 86 1999 1142-1150
    • (1999) J. Appl. Physiol. , vol.86 , pp. 1142-1150
    • Harty, E.R.1    Corfield, D.R.2    Schwartzstein, R.M.3
  • 48
    • 0031833030 scopus 로고    scopus 로고
    • Qualitative aspects of exertional dyspnea in patients with interstitial lung disease
    • D.E. O'Donnell L.K.L. Chau K.A. Webb Qualitative aspects of exertional dyspnea in patients with interstitial lung disease J Appl Physiol 84 1998 2000-2009
    • (1998) J. Appl. Physiol. , vol.84 , pp. 2000-2009
    • O'Donnell, D.E.1    Chau, L.K.L.2    Webb, K.A.3
  • 49
    • 0029934181 scopus 로고    scopus 로고
    • Mechanisms of relief exertional breathlessness following unilateral bullectomy and lung volume reduction surgery in emphysema
    • D.E. O'Donnell A.K. Webb J.C. Bertley et al. Mechanisms of relief exertional breathlessness following unilateral bullectomy and lung volume reduction surgery in emphysema Chest 110 1996 18-27
    • (1996) Chest , vol.110 , pp. 18-27
    • O'Donnell, D.E.1    Webb, A.K.2    Bertley, J.C.3
  • 50
    • 0031889431 scopus 로고    scopus 로고
    • Effect of lung volume reduction surgery on neuromechanical coupling of the diaphragm
    • F. Laghi A. Jubran A. Topeli et al. Effect of lung volume reduction surgery on neuromechanical coupling of the diaphragm Am J Respir Crit Care Med 157 2 1998 475-483
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , Issue.2 , pp. 475-483
    • Laghi, F.1    Jubran, A.2    Topeli, A.3
  • 51
    • 0038467576 scopus 로고    scopus 로고
    • Exercise training improves exertional dyspnea in patients with COPD: Evidence of role of mechanical factors
    • F. Gigliotti C. Coli R. Bianchi et al. Exercise training improves exertional dyspnea in patients with COPD: Evidence of role of mechanical factors Chest 123 2003 1794-1802
    • (2003) Chest , vol.123 , pp. 1794-1802
    • Gigliotti, F.1    Coli, C.2    Bianchi, R.3
  • 52
    • 0029880016 scopus 로고    scopus 로고
    • Lung mechanics and dyspnea after lung transplantation for chronic airflow obstruction
    • F.J. Martinez J.B. Orens R.I. Whyte et al. Lung mechanics and dyspnea after lung transplantation for chronic airflow obstruction Am J Respir Crit Care Med 153 1996 1536-1543
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 1536-1543
    • Martinez, F.J.1    Orens, J.B.2    Whyte, R.I.3
  • 53
    • 0023251097 scopus 로고
    • Breathlessness and respiratory mechanics during reflex or voluntary hyperinflation in patients with chronic airflow limitation
    • S. Freedman R. Lane A. Guz Breathlessness and respiratory mechanics during reflex or voluntary hyperinflation in patients with chronic airflow limitation Clin Sci 73 1987 311-318
    • (1987) Clin. Sci. , vol.73 , pp. 311-318
    • Freedman, S.1    Lane, R.2    Guz, A.3
  • 55
    • 0014290814 scopus 로고
    • The pulmonary circulation in chronic bronchitis at rest and during exercise breathing air and 80% oxygen
    • K. Horsfield N. Segel J.M. Bishop The pulmonary circulation in chronic bronchitis at rest and during exercise breathing air and 80% oxygen Clin Sci 43 1968 473-483
    • (1968) Clin. Sci. , vol.43 , pp. 473-483
    • Horsfield, K.1    Segel, N.2    Bishop, J.M.3
  • 56
    • 0021703350 scopus 로고
    • Right ventricular performance and central circulatory hemodynamics during upright exercise in patients with chronic obstructive pulmonary disease
    • D.A. Mahler B.N. Brent J. Loke B.L. Zaret R.A. Matthay Right ventricular performance and central circulatory hemodynamics during upright exercise in patients with chronic obstructive pulmonary disease Am Rev Respir Dis 130 1984 722-729
    • (1984) Am. Rev. Respir. Dis. , vol.130 , pp. 722-729
    • Mahler, D.A.1    Brent, B.N.2    Loke, J.3    Zaret, B.L.4    Matthay, R.A.5
  • 58
    • 0020960463 scopus 로고
    • Cardiovascular function in cor pulmonale
    • R.A. Mattay H.J. Berger Cardiovascular function in cor pulmonale Clin Chest Med 4 1983 269-295
    • (1983) Clin. Chest Med. , vol.4 , pp. 269-295
    • Mattay, R.A.1    Berger, H.J.2
  • 60
    • 0021246052 scopus 로고
    • Mechanism of decreased left ventricular stroke volume during inspiration in man
    • M. Karam R.A. Wise T.K. Natarajan S. Permutt H.N. Wagner Mechanism of decreased left ventricular stroke volume during inspiration in man Circulation 69 1984 866-873
    • (1984) Circulation , vol.69 , pp. 866-873
    • Karam, M.1    Wise, R.A.2    Natarajan, T.K.3    Permutt, S.4    Wagner, H.N.5
  • 61
    • 0030998435 scopus 로고    scopus 로고
    • Respiratory muscle work compromises leg blood flow during maximal exercise
    • C.A. Harms M.A. Babcock S.R. McClaran et al. Respiratory muscle work compromises leg blood flow during maximal exercise J Appl Physiol 82 1997 1573-1583
    • (1997) J. Appl. Physiol. , vol.82 , pp. 1573-1583
    • Harms, C.A.1    Babcock, M.A.2    McClaran, S.R.3
  • 62
    • 0033911527 scopus 로고    scopus 로고
    • Effects of respiratory muscle work on exercise performance
    • C.A. Harms T.J. Wetter C.M. St. Croix et al. Effects of respiratory muscle work on exercise performance J Appl Physiol 89 2000 131-138
    • (2000) J. Appl. Physiol. , vol.89 , pp. 131-138
    • Harms, C.A.1    Wetter, T.J.2    St. Croix, C.M.3
  • 63
    • 0033405249 scopus 로고    scopus 로고
    • Ventilatory assistance improves exercise endurance in stable congestive heart failure
    • D.E. O'Donnell C. D'Arsigny S. Raj et al. Ventilatory assistance improves exercise endurance in stable congestive heart failure Am J Respir Crit Care Med 160 1999 1804-1811
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 1804-1811
    • O'Donnell, D.E.1    D'Arsigny, C.2    Raj, S.3
  • 64
    • 0025364695 scopus 로고
    • Sensation of dyspnea during hypercapnia, exercise, and voluntary hyperventilation
    • T. Chonan M.B. Mulholland J. Leitner et al. Sensation of dyspnea during hypercapnia, exercise, and voluntary hyperventilation J Appl Physiol 68 1990 2100-2106
    • (1990) J. Appl. Physiol. , vol.68 , pp. 2100-2106
    • Chonan, T.1    Mulholland, M.B.2    Leitner, J.3
  • 67
    • 0032895332 scopus 로고    scopus 로고
    • Ventilatory drive at rest and perception of exertional dyspnea in severe COPD
    • J.M. Marin M. Montes de Oca J. Rassulo et al. Ventilatory drive at rest and perception of exertional dyspnea in severe COPD Chest 115 5 1999 1293-1300
    • (1999) Chest , vol.115 , Issue.5 , pp. 1293-1300
    • Marin, J.M.1    Montes de Oca, M.2    Rassulo, J.3
  • 69
    • 0023903541 scopus 로고
    • Effect of hyperoxia and hypoxia on exercise-induced breathlessness in normal subjects
    • N. Chronos L. Adams A. Guz Effect of hyperoxia and hypoxia on exercise-induced breathlessness in normal subjects Clin Sci 74 1988 531-537
    • (1988) Clin. Sci. , vol.74 , pp. 531-537
    • Chronos, N.1    Adams, L.2    Guz, A.3
  • 70
    • 0023193947 scopus 로고
    • Arterial oxygen saturation and breathlessness in patients with chronic obstructive airway disease
    • R. Lane A. Cockcroft L. Adams et al. Arterial oxygen saturation and breathlessness in patients with chronic obstructive airway disease Clin Sci 72 1987 693-698
    • (1987) Clin. Sci. , vol.72 , pp. 693-698
    • Lane, R.1    Cockcroft, A.2    Adams, L.3
  • 71
    • 0021192760 scopus 로고
    • Relationship between ventilation and breathlessness during exercise in chronic obstructive airway disease is not altered by prevention of hypoxemia
    • C.R. Swinburn I.M. Wakefield P.W. Jones Relationship between ventilation and breathlessness during exercise in chronic obstructive airway disease is not altered by prevention of hypoxemia Clin Sci 67 1984 146-149
    • (1984) Clin. Sci. , vol.67 , pp. 146-149
    • Swinburn, C.R.1    Wakefield, I.M.2    Jones, P.W.3
  • 72
    • 0025042988 scopus 로고
    • The effects of hypoxia and hypercapnia on perceived breathlessness during exercise in humans
    • R. Lane A. Adams A. Guz The effects of hypoxia and hypercapnia on perceived breathlessness during exercise in humans J Physiol 428 1990 579-593
    • (1990) J. Physiol. , vol.428 , pp. 579-593
    • Lane, R.1    Adams, A.2    Guz, A.3
  • 73
    • 0020060408 scopus 로고
    • Effect of oxygen on breathing during exercise in patients with chronic obstructive lung disease
    • G. Scano A. van Meerhaeghe R. Willeput et al. Effect of oxygen on breathing during exercise in patients with chronic obstructive lung disease Eur J Respir Dis 63 1982 23-30
    • (1982) Eur. J. Respir. Dis. , vol.63 , pp. 23-30
    • Scano, G.1    van Meerhaeghe, A.2    Willeput, R.3
  • 74
    • 0031058778 scopus 로고    scopus 로고
    • Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation
    • D.E. O'Donnell D.I. Bain K.A. Webb Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation Am J Respir Crit Care Med 155 1997 530-535
    • (1997) Am. J. Respir. Crit. Care Med. , vol.155 , pp. 530-535
    • O'Donnell, D.E.1    Bain, D.I.2    Webb, K.A.3
  • 75
    • 0035064316 scopus 로고    scopus 로고
    • Effects of hyperoxia on ventilatory limitation during exercise in advanced chronic obstructive pulmonary disease
    • D.E. O'Donnell C. D'Arsigny K.A. Webb Effects of hyperoxia on ventilatory limitation during exercise in advanced chronic obstructive pulmonary disease Am J Respir Crit Care Med 163 2001 892-898
    • (2001) Am. J. Respir. Crit. Care Med. , vol.163 , pp. 892-898
    • O'Donnell, D.E.1    D'Arsigny, C.2    Webb, K.A.3
  • 76
    • 0021932949 scopus 로고
    • Ventilatory muscle function during exercise in air and oxygen in patients with chronic air-flow limitation
    • P.T.P. Bye S.A. Esau R.D. Levy et al. Ventilatory muscle function during exercise in air and oxygen in patients with chronic air-flow limitation Am Rev Respir Dis 132 1985 236-240
    • (1985) Am. Rev. Respir. Dis. , vol.132 , pp. 236-240
    • Bye, P.T.P.1    Esau, S.A.2    Levy, R.D.3
  • 77
  • 78
    • 0242301642 scopus 로고    scopus 로고
    • Benefits of supplemental oxygen in exercise training in nonspecific chronic obstructive pulmonary disease patients
    • M. Emtner J. Porszasz M. Burns et al. Benefits of supplemental oxygen in exercise training in nonspecific chronic obstructive pulmonary disease patients Am J Respir Crit Care Med 168 2003 1034-1042
    • (2003) Am. J. Respir. Crit. Care Med. , vol.168 , pp. 1034-1042
    • Emtner, M.1    Porszasz, J.2    Burns, M.3
  • 79
    • 0027411375 scopus 로고
    • Metabolic acidosis and breathlessness during exercise and hypercapnia in man
    • R. Lane L. Adams Metabolic acidosis and breathlessness during exercise and hypercapnia in man J Physiol 461 1993 47-61
    • (1993) J. Physiol. , vol.461 , pp. 47-61
    • Lane, R.1    Adams, L.2


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