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Volumn 11, Issue 10, 2005, Pages 1073-1081

Tumor-targeted, systemic delivery of therapeutic viral vectors using hitchhiking on antigen-specific T cells

Author keywords

[No Author keywords available]

Indexed keywords

HEPARANASE; INTERLEUKIN 12; RETROVIRUS VECTOR; THYMIDINE KINASE; VIRUS VECTOR;

EID: 27144483926     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1297     Document Type: Article
Times cited : (132)

References (50)
  • 1
    • 0033959447 scopus 로고    scopus 로고
    • Cancer gene therapy: Hard lessons and new courses
    • Vile, R.G., Russell, S.J. & Lemoine, N.R. Cancer gene therapy: hard lessons and new courses. Gene Ther. 7, 2-8 (2000).
    • (2000) Gene Ther. , vol.7 , pp. 2-8
    • Vile, R.G.1    Russell, S.J.2    Lemoine, N.R.3
  • 2
    • 0036376654 scopus 로고    scopus 로고
    • Cells as vehicles for cancer gene therapy: The missing link between targeted vectors and systemic delivery
    • Harrington, K. et al. Cells as vehicles for cancer gene therapy: The missing link between targeted vectors and systemic delivery. Hum. Gene Ther. 13, 1263-1280 (2002).
    • (2002) Hum. Gene Ther. , vol.13 , pp. 1263-1280
    • Harrington, K.1
  • 3
    • 0032823293 scopus 로고    scopus 로고
    • Initial binding of murine leukemia virus particles to cells does not require specific Env-receptor interaction
    • Pizzato, M., Marlow, S.A., Blair, E.D. & Takeuchi, Y. Initial binding of murine leukemia virus particles to cells does not require specific Env-receptor interaction. J. Virol. 73, 8599-8611 (1999).
    • (1999) J. Virol. , vol.73 , pp. 8599-8611
    • Pizzato, M.1    Marlow, S.A.2    Blair, E.D.3    Takeuchi, Y.4
  • 4
    • 0036200976 scopus 로고    scopus 로고
    • Tumor antigen-specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor-modified T cells
    • Chester, J. et al. Tumor antigen-specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor-modified T cells. Nat. Biotechnol. 20, 256-263 (2002).
    • (2002) Nat. Biotechnol. , vol.20 , pp. 256-263
    • Chester, J.1
  • 5
    • 0038407586 scopus 로고    scopus 로고
    • Pharmacologically regulated production of targeted retrovirus from T cells for systemic anti-tumor gene therapy
    • Crittenden, M. et al. Pharmacologically regulated production of targeted retrovirus from T cells for systemic anti-tumor gene therapy. Cancer Res. 63, 3173-3180 (2003).
    • (2003) Cancer Res. , vol.63 , pp. 3173-3180
    • Crittenden, M.1
  • 6
    • 0034670078 scopus 로고    scopus 로고
    • Transcriptional control: An essential component of cancer gene therapy strategies?
    • Harrington, K.J., Linardakis, E. & Vile, R.G. Transcriptional control: an essential component of cancer gene therapy strategies? Adv. Drug Deliv. Rev. 44, 167-184 (2000).
    • (2000) Adv. Drug Deliv. Rev. , vol.44 , pp. 167-184
    • Harrington, K.J.1    Linardakis, E.2    Vile, R.G.3
  • 7
    • 5144226237 scopus 로고    scopus 로고
    • Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes
    • Rosenberg, S.A. & Dudley, M.E. Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes. Proc. Natl. Acad. Sci. USA 101, Suppl. 2, 14639-14645 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.2 SUPPL. , pp. 14639-14645
    • Rosenberg, S.A.1    Dudley, M.E.2
  • 8
    • 0141688283 scopus 로고    scopus 로고
    • Adoptive-cell-transfer therapy for the treatment of patients with cancer
    • Dudley, M.E. & Rosenberg, S.A. Adoptive-cell-transfer therapy for the treatment of patients with cancer. Nat. Rev. Cancer 3, 666-676 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 666-676
    • Dudley, M.E.1    Rosenberg, S.A.2
  • 10
    • 0034606276 scopus 로고    scopus 로고
    • Melanocyte destruction after antigen-specific immunotherapy of melanoma: Direct evidence of T cell-mediated vitiligo
    • Yee, C. et al. Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of T cell-mediated vitiligo. J. Exp. Med. 192, 1637-1644 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 1637-1644
    • Yee, C.1
  • 11
    • 17944379652 scopus 로고    scopus 로고
    • Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma
    • Dudley, M.E. et al. Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma. J. Immunother. 24, 363-373 (2001).
    • (2001) J. Immunother. , vol.24 , pp. 363-373
    • Dudley, M.E.1
  • 12
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • Dudley, M.E. et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298, 850-854 (2002).
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1
  • 13
    • 10344234215 scopus 로고    scopus 로고
    • + T cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction
    • + T cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction. J. Immunol. 173, 7209-7216 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 7209-7216
    • Palmer, D.1
  • 14
    • 0034796426 scopus 로고    scopus 로고
    • Evidence for nonspecific adsorption of targeted retrovirus vector particles to cells
    • Pizzato, M. et al. Evidence for nonspecific adsorption of targeted retrovirus vector particles to cells. Gene Ther. 8, 1088-1096 (2001).
    • (2001) Gene Ther. , vol.8 , pp. 1088-1096
    • Pizzato, M.1
  • 15
    • 0029128628 scopus 로고
    • Retrovirus receptors
    • Weiss, R.A. & Chetankuma, S.T. Retrovirus receptors. Cell 82, 531-533 (1995).
    • (1995) Cell , vol.82 , pp. 531-533
    • Weiss, R.A.1    Chetankuma, S.T.2
  • 17
    • 0036791104 scopus 로고    scopus 로고
    • Enhancing the efficacy of a weak allogeneic melanoma vaccine by viral fusogenic membrane glycoprotein-mediated tumor cell-tumor cell fusion
    • Linardakis, E. et al. Enhancing the efficacy of a weak allogeneic melanoma vaccine by viral fusogenic membrane glycoprotein-mediated tumor cell-tumor cell fusion. Cancer Res. 62, 5495-5504 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 5495-5504
    • Linardakis, E.1
  • 18
    • 0346118917 scopus 로고    scopus 로고
    • Regulation of inducible heparanase gene transcription in activated T cells by early growth response 1
    • de Mestre, A.M., Khachigian, L.M., Santiago, F.S., Staykova, M.A. & Hulett, M.D. Regulation of inducible heparanase gene transcription in activated T cells by early growth response 1. J. Biol. Chem. 278, 50377-50385 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 50377-50385
    • De Mestre, A.M.1    Khachigian, L.M.2    Santiago, F.S.3    Staykova, M.A.4    Hulett, M.D.5
  • 19
    • 0028138555 scopus 로고
    • Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell
    • Takeuchi, Y., Cosset, F.L., Lachmann, P.J., Okada, H., Weiss, R.A. & Collins, M.K.L. Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell. J. Virol. 68, 8001-8007 (1994).
    • (1994) J. Virol. , vol.68 , pp. 8001-8007
    • Takeuchi, Y.1    Cosset, F.L.2    Lachmann, P.J.3    Okada, H.4    Weiss, R.A.5    Collins, M.K.L.6
  • 20
    • 0031885545 scopus 로고    scopus 로고
    • Tumour cell expression of B7 costimulatory molecules and interleukin-12 or granulocyte-macrophage colony stimulating factor induces a local antitumour response and may generate systemic protective immunity
    • Chong, H., Todryk, S., Hutchinson, G., Hart, I.R. & Vile, R.G. Tumour cell expression of B7 costimulatory molecules and interleukin-12 or granulocyte-macrophage colony stimulating factor induces a local antitumour response and may generate systemic protective immunity. Gene Ther. 5, 223-232 (1998).
    • (1998) Gene Ther. , vol.5 , pp. 223-232
    • Chong, H.1    Todryk, S.2    Hutchinson, G.3    Hart, I.R.4    Vile, R.G.5
  • 21
    • 0027255414 scopus 로고
    • Use of tissue-specific expression of the herpes simplex virus thymidine kinase gene to inhibit growth of established murine melanomas following direct intratumoral injection of DNA
    • Vile, R.G. & Hart, I.R. Use of tissue-specific expression of the herpes simplex virus thymidine kinase gene to inhibit growth of established murine melanomas following direct intratumoral injection of DNA. Cancer Res. 53, 3860-3864 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 3860-3864
    • Vile, R.G.1    Hart, I.R.2
  • 22
    • 0028500863 scopus 로고
    • A comparison of the properties of different retroviral vectors containing the murine tyrosinase promoter to achieve transcriptionally targeted expression of the HSVtk or IL-2 genes
    • Vile, R., Miller, N., Chernajovsky, Y. & Hart, I.R. A comparison of the properties of different retroviral vectors containing the murine tyrosinase promoter to achieve transcriptionally targeted expression of the HSVtk or IL-2 genes. Gene Ther. 1, 307-316 (1994).
    • (1994) Gene Ther. , vol.1 , pp. 307-316
    • Vile, R.1    Miller, N.2    Chernajovsky, Y.3    Hart, I.R.4
  • 23
    • 0031984750 scopus 로고    scopus 로고
    • Exchange of viral promoter/enhancer elements with heterologous regulatory sequences generates targeted hybrid long terminal repeat vectors for gene therapy of melanoma
    • Diaz, R.M., Eisen, T., Hart, I.R. & Vile, R.G. Exchange of viral promoter/enhancer elements with heterologous regulatory sequences generates targeted hybrid long terminal repeat vectors for gene therapy of melanoma. J. Virol. 72, 789-795 (1998).
    • (1998) J. Virol. , vol.72 , pp. 789-795
    • Diaz, R.M.1    Eisen, T.2    Hart, I.R.3    Vile, R.G.4
  • 24
    • 0034598905 scopus 로고    scopus 로고
    • DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
    • Geijtenbeek, T.B. et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 100, 587-597 (2000).
    • (2000) Cell , vol.100 , pp. 587-597
    • Geijtenbeek, T.B.1
  • 25
    • 0037237790 scopus 로고    scopus 로고
    • Syndecan captures, protects, and transmits HIV to T lymphocytes
    • Bobardt, M.D. et al. Syndecan captures, protects, and transmits HIV to T lymphocytes. Immunity 18, 27-39 (2003).
    • (2003) Immunity , vol.18 , pp. 27-39
    • Bobardt, M.D.1
  • 26
  • 27
    • 0036631776 scopus 로고    scopus 로고
    • Heparin binds to murine leukemia virus and inhibits Env-independent attachment and infection
    • Walker, S.J., Pizzato, M., Takeuchi, Y. & Devereux, S. Heparin binds to murine leukemia virus and inhibits Env-independent attachment and infection. J. Virol. 76, 6909-6918 (2002).
    • (2002) J. Virol. , vol.76 , pp. 6909-6918
    • Walker, S.J.1    Pizzato, M.2    Takeuchi, Y.3    Devereux, S.4
  • 28
    • 0023687871 scopus 로고
    • Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation
    • Saksela, O., Moscatelli, D., Sommer, A. & Rifkin, D.B. Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation. J. Cell Biol. 107, 743-751 (1988).
    • (1988) J. Cell Biol. , vol.107 , pp. 743-751
    • Saksela, O.1    Moscatelli, D.2    Sommer, A.3    Rifkin, D.B.4
  • 29
    • 1542319836 scopus 로고    scopus 로고
    • Heparanase degrades syndecan-1 and perlecan heparan sulfate: Functional implications for tumor cell invasion
    • Reiland, J. et al. Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion. J. Biol. Chem. 279, 8047-8055 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 8047-8055
    • Reiland, J.1
  • 30
    • 0033028789 scopus 로고    scopus 로고
    • Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis
    • Hulett, M.D. et al. Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis. Nat. Med. 5, 803-809 (1999).
    • (1999) Nat. Med. , vol.5 , pp. 803-809
    • Hulett, M.D.1
  • 31
    • 0032879625 scopus 로고    scopus 로고
    • Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides
    • Miao, H.Q. et al. Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides. Int. J. Cancer 83, 424-431 (1999).
    • (1999) Int. J. Cancer , vol.83 , pp. 424-431
    • Miao, H.Q.1
  • 32
    • 0033057962 scopus 로고    scopus 로고
    • Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis
    • Vlodavsky, I. et al. Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis. Nat. Med. 5, 793-802 (1999).
    • (1999) Nat. Med. , vol.5 , pp. 793-802
    • Vlodavsky, I.1
  • 33
    • 0037108707 scopus 로고    scopus 로고
    • Interleukin 18 gene transfer expands the repertoire of anti tumor Th-1 type immunity elicited by dendritic cell based vaccines in association with enhanced therapeutic efficacy
    • Tatsumi, T., Gambotto, A., Robbins, P.D. & Storkus, W.J. Interleukin 18 gene transfer expands the repertoire of anti tumor Th-1 type immunity elicited by dendritic cell based vaccines in association with enhanced therapeutic efficacy. Cancer Res. 62, 5853-5858 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 5853-5858
    • Tatsumi, T.1    Gambotto, A.2    Robbins, P.D.3    Storkus, W.J.4
  • 34
    • 0030917683 scopus 로고    scopus 로고
    • Generation of an anti-tumour immune response in a non-immunogenic tumour: HSVtk-killing in vivo stimulates a mononuclear cell infiltrate and a Th1-like profile of intratumoural cytokine expression
    • Vile, R.G. et al. Generation of an anti-tumour immune response in a non-immunogenic tumour: HSVtk-killing in vivo stimulates a mononuclear cell infiltrate and a Th1-like profile of intratumoural cytokine expression. Int. J. Cancer 71, 267-274 (1997).
    • (1997) Int. J. Cancer , vol.71 , pp. 267-274
    • Vile, R.G.1
  • 35
    • 0031836938 scopus 로고    scopus 로고
    • Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression
    • Melcher, A. et al. Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression. Nat. Med. 4, 581-587 (1998).
    • (1998) Nat. Med. , vol.4 , pp. 581-587
    • Melcher, A.1
  • 36
    • 0033179274 scopus 로고    scopus 로고
    • Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake
    • Todryk, S. et al. Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake. J. Immunol. 163, 1398-1408 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 1398-1408
    • Todryk, S.1
  • 37
    • 10344261422 scopus 로고    scopus 로고
    • Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
    • Robbins, P.F. et al. Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy. J. Immunol. 173, 7125-7130 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 7125-7130
    • Robbins, P.F.1
  • 38
    • 4444345447 scopus 로고    scopus 로고
    • A simple method to cure established tumors by inflammatory killing of normal cells
    • Daniels, G. et al. A simple method to cure established tumors by inflammatory killing of normal cells. Nat. Biotechnol. 22, 1125-1132 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1125-1132
    • Daniels, G.1
  • 39
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferations in two patients after gene therapy for SCID-X1
    • Hacein-Bey-Abina, S. et al. LMO2-associated clonal T cell proliferations in two patients after gene therapy for SCID-X1. Science 302, 415-419 (2003).
    • (2003) Science , vol.302 , pp. 415-419
    • Hacein-Bey-Abina, S.1
  • 40
    • 19244366262 scopus 로고    scopus 로고
    • Success for gene therapy: Render unto Caesar that which is Caesar's
    • Qiao, J., Diaz, R.M. & Vile, R. Success for gene therapy: render unto Caesar that which is Caesar's. Genome Biol. 5, 237-240 (2004).
    • (2004) Genome Biol. , vol.5 , pp. 237-240
    • Qiao, J.1    Diaz, R.M.2    Vile, R.3
  • 41
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller, D.G., Adam, M.A. & Miller, A.D. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol. Cell. 10, 4239-4242 (1990).
    • (1990) Mol. Cell. , vol.10 , pp. 4239-4242
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 42
    • 11844292744 scopus 로고    scopus 로고
    • Shuttle of lentiviral vectors via transplanted cells in vivo
    • Blomer, U., Gruh, I., Witschel, H., Haverich, A. & Martin, U. Shuttle of lentiviral vectors via transplanted cells in vivo. Gene Ther. 12, 67-74 (2005).
    • (2005) Gene Ther. , vol.12 , pp. 67-74
    • Blomer, U.1    Gruh, I.2    Witschel, H.3    Haverich, A.4    Martin, U.5
  • 44
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern, J.P. & Land, H. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18, 3587-3596 (1990).
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3587-3596
    • Morgenstern, J.P.1    Land, H.2
  • 45
    • 0345116028 scopus 로고
    • Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1
    • Wagner, M.J., Sharp, J.A. & Summers, W.C. Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1. Proc. Natl. Acad. Sci. USA 78, 1441-1445 (1981).
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 1441-1445
    • Wagner, M.J.1    Sharp, J.A.2    Summers, W.C.3
  • 46
    • 0024239024 scopus 로고
    • Construction and use of a safe and efficient amphotropic packaging cell line
    • Markowitz, D., Goff, S. & Bank, A. Construction and use of a safe and efficient amphotropic packaging cell line. Virology 167, 400-406 (1988).
    • (1988) Virology , vol.167 , pp. 400-406
    • Markowitz, D.1    Goff, S.2    Bank, A.3
  • 47
    • 0025834275 scopus 로고
    • Construction and properties of retroviral packaging cells based on gibbon ape leukemia virus
    • Miller, A.D. et al. Construction and properties of retroviral packaging cells based on gibbon ape leukemia virus. J. Virol. 65, 2220-2224 (1991).
    • (1991) J. Virol. , vol.65 , pp. 2220-2224
    • Miller, A.D.1
  • 48
    • 0027228422 scopus 로고
    • Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
    • Burns, J.C., Friedmann, T., Driever, W., Burrascano, M. & Yee, J. K. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl. Acad. Sci. USA 90, 8033-8037 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8033-8037
    • Burns, J.C.1    Friedmann, T.2    Driever, W.3    Burrascano, M.4    Yee, J.K.5
  • 49
    • 0028178784 scopus 로고
    • T cell receptor antagonistic peptides induce positive selection
    • Hogquist, K.A. et al. T cell receptor antagonistic peptides induce positive selection. Cell 76, 17-27 (1994).
    • (1994) Cell , vol.76 , pp. 17-27
    • Hogquist, K.A.1


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