No association of - 1438G/A polymorphism in promoter region of 5-HT2A-receptor gene with antipsychotic agent-induced weight gain

Chinese Journal of Medical Genetics

Volumn 22, Issue 5, 2005, Pages 575-576

  Mou, Xiao Dong ^a,b   Zhang, Zhi Jun ^a,b   Yao, Zhi Jian ^b   Liu, Wen ^b   Zhang, Xiang Rong ^b   Shi, Jia Bo ^b   Sun, Jing ^b  

^a AFFILIATED ZHONGDA HOSPITAL OF SOUTHEAST UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

5 hydroxytryptamine 2A receptor; Schizophrenia; Weight gain

Indexed keywords

CHLORPROMAZINE; NEUROLEPTIC AGENT; RISPERIDONE; SEROTONIN 2A RECEPTOR;

ARTICLE; BODY WEIGHT; CHINESE; DNA POLYMORPHISM; FAMILY; GENE FREQUENCY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHIZOPHRENIA; SIDE EFFECT; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME; WEIGHT GAIN;

ADULT; ANTIPSYCHOTIC AGENTS; CHLORPROMAZINE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROMOTER REGIONS, GENETIC; RECEPTOR, SEROTONIN, 5-HT2A; RISPERIDONE; SCHIZOPHRENIA; WEIGHT GAIN;

EID: 27144456526     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HTR2C receptor gene polymorphism. Lancet, 2002, 359:2086-2087.
2. Collier DA, Arranz MJ, Li T, et al. Association between 5-HT2A gene promoter polymorphism and anorexia nervosa. Lancet, 1997, 350:412-416.
3. Allison DB. Transmission-disequilibrium tests for quantitative traits. Am J Hum Genet 1997, 60:676-690.
4. Monks SA, Kaplan NL. Removing the sampling restrictions from family-based tests of association for a quantitative-trait locus. Am J Hum Genet, 2000, 66:576-592.
5. Cardon LR, Bell JL. Association study designs for complex diseases. Nat Rev Genet, 2001, 2:91-99.
6. Veenstra-Vander Weele J, Anderson GM, Cook EH Jr. Pharmacogenetics and the serotonin system: initial studies and future directions. Eur J Pharmacol, 2000, 410:165-181.
7. Liu Q, Zhou DF, Zhou M. The association between polymorphism of 5-HT2A receptor gene and Olanzapine induced weight gain. Chin Mental Health J, 2003, 17:696-698.