Expression microarray analysis and oligo array comparative genomic hybridization of acquired gemcitabine resistance in mouse colon reveals selection for chromosomal aberrations

Cancer Research

Volumn 65, Issue 22, 2005, Pages 10208-10213

  Van De Wiel, Mark A ^a,b   Costa, Jose L ^b   Smid, Kees ^b   Oudejans, Cees B M ^b   Bergman, Andries M ^b   Meijer, Gerrit A ^b   Peters, Godefridus J ^b   Ylstra, Bauke ^b  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GEMCITABINE;

ANIMAL TISSUE; ARTICLE; CANCER RESISTANCE; CHROMOSOME 7; CHROMOSOME ABERRATION; COLON TUMOR; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA MICROARRAY; DNA REPLICATION; DRUG TOLERABILITY; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENE OVEREXPRESSION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CHROMOSOME ABERRATIONS; COLONIC NEOPLASMS; DEOXYCYTIDINE; DNA REPLICATION; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION; MICE; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 27144454948     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-0760     Document Type: Article

References (19)

1. Bergman AM, Pinedo HM, Peters GJ. Determinants of resistance to 2′,2′-difluorodeoxycytidine (gemcitabine). Drug Resist Updat 2002;5:19-33.
2. Resell R, Danenberg KD, Alberola V, et al. Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin Cancer Res 2004;10:1318-25.
3. Davidson JD, Ma L, Flagella M, Geeganage S, Gelbert LM, Slapak CA. An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines. Cancer Res 2004;64:3761-6.
4. Bergman AM, Eijk PP, Smid K, et al. In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant. Cancer Res. In press 2005.
5. Newton MA, Noueiry A, Sarkar D, Ahlquist P. Detecting differential gene expression with a semiparametric hierarchical mixture method. Biostatistics 2004;5:155-76.
6. Broet P, Lewin A, Richardson S, Dalmasso C, Magdelenat H. A mixture model-based strategy for selecting sets of genes in multiclass response microarray experiments. Bioinformatics 2004;20:2562-71.
7. Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 2001;98:10869-74.
8. Carvalho B, Ouwerkerk E, Meijer GA, Ylstra B. High resolution microarray comparative genomic hybridisation analysis using spotted oligonucleotides. J Clin Pathol 2004;57:644-6.
9. Snijders AM, Nowak N, Segraves R, et al. Assembly of microarrays for genome-wide measurement of DNA copy number. Nat Genet 2001;29:263-4.
10. Jong K, Marchiori E, Meijer G, Vaart AV, Ylstra B. Breakpoint identification and smoothing of array comparative genomic hybridization data. Bioinformatics 2004;20:3636-7.
11. Goan YG, Zhou B, Hu E, Mi S, Yen Y. Overexpression of ribonucleotide reductase as a mechanism of resistance to 2,2-difluorodeoxycytidine in the human KB cancer cell line. Cancer Res 1999;59:4204-7.
12. Bulger M, van Doorninck JH, Saitoh N, et al. Conservation of sequence and structure flanking the mouse and human β-globin loci: the β-globin genes are embedded within an array of odorant receptor genes. Proc Natl Acad Sci U S A 1999;96:5129-34.
13. Bank A. Understanding globin regulation in β-thalassemia: it's as simple as α, β, γ, δ. J Clin Invest 2005;115:1470-3.
14. Trimborn T, Gribnau J, Grosveld F, Fraser P. Mechanisms of developmental control of transcription in the murine α- and β-globin loci. Genes Dev 1999;13:112-4.
15. Anderson J, Gordon A, McManus A, Shipley J, Pritchard-Jones K. Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma. Neoplasia 1999;1:340-8.
16. Arlt MF, Casper AM, Glover TW. Common fragile sites. Cytogenet Genome Res 2003;100:92-100.
17. Glover TW. Instability at chromosomal fragile sites. Recent Results Cancer Res 1998;154:185-99.
18. Debatisse M, Toledo F, Anglana M. Replication initiation in mammalian cells: changing preferences. Cell Cycle 2004;3:19-21.
19. Yasui K, Mihara S, Zhao C, et al. Alteration in copy numbers of genes as a mechanism for acquired drug resistance. Cancer Res 2004;64:1403-10.