Induction of central signalling pathways and select functional effects in human platelets by β-boswellic acid

British Journal of Pharmacology

Volumn 146, Issue 4, 2005, Pages 514-524

  Poeckel, Daniel ^a   Tausch, Lars ^a   Altmann, Anja ^a   Feißt, Christian ^a   Klinkhardt, Ute ^b   Graff, Jochen ^b   Harder, Sebastian ^b   Werz, Oliver ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Akt; Arachidonic acid; Boswellic acids; Calcium; Mitogen activated protein kinases; Platelets; Thrombin

Indexed keywords

11 KETOBOSWELLIC ACID; 3 O ACETYL 11 KETOBOSWELLIC ACID; 3 O ACETYLBOSWELLIC ACID; ARACHIDONIC ACID; BETA BOSWELLIC ACID; BOSWELLIC ACID; CALCIUM ION; COLLAGEN; INOSITOL 1,4,5 TRISPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPASE C; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; THROMBIN; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM MOBILIZATION; CELL STIMULATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; STORAGE; THROMBIN TIME; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION;

ANALYSIS OF VARIANCE; ANTI-INFLAMMATORY AGENTS; ARACHIDONIC ACID; BLOOD PLATELETS; CALCIUM SIGNALING; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASE C; PHOSPHORYLATION; PLATELET AGGREGATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; THROMBIN; TIME FACTORS; TRITERPENES; TYPE C PHOSPHOLIPASES;

EID: 27144452018     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706366     Document Type: Article

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