κ-Opioid receptor agonist inhibition of HIV-1 envelope glycoprotein-mediated membrane fusion and CXCR4 expression on CD4+ lymphocytes

Biochemical Pharmacology

Volumn 63, Issue 6, 2002, Pages 1037-1041

  Lokensgard, James R ^a,b   Gekker, Genya ^a,b   Peterson, Phillip K ^a,b  

^a MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Opioid receptor; CD4+lymphocytes; CXCR4; HIV; U50,488

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; 5 BROMO 4 CHLORO 3 INDOYL BETA DEXTRO GALACTOPYRANOSIDE; CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR ANTAGONIST; NORBINALTORPHIMINE; PYRANOSIDE; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN;

ARTICLE; CELL FUSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; GENE ACTIVATION; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INHIBITION KINETICS; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REPORTER GENE; STAINING; VACCINIA; VIRUS INHIBITION;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANALGESICS, NON-NARCOTIC; CD4-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; GENE EXPRESSION; HELA CELLS; HIV ENVELOPE PROTEIN GP120; HUMANS; MEMBRANE FUSION; RECEPTORS, CXCR4; RECEPTORS, OPIOID, KAPPA;

EID: 0037087640     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)00875-4     Document Type: Article

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