Oncofoetal fibronectin - A tumour-specific marker in detecting minimal residual disease in differentiated thyroid carcinoma

British Journal of Cancer

Volumn 93, Issue 5, 2005, Pages 565-570

  Hesse, E ^a   Musholt, P B ^a,b   Potter, E ^a   Petrich, T ^a   Wehmeier, M ^a   Von Wasielewski, R ^a   Lichtinghagen, R ^a   Musholt, T J ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Minimal residual disease; Molecular diagnostics; Oncofoetal fibronectin mRNA; Real time RT PCR; Thyroglobulin mRNA; Thyroid cancer

Indexed keywords

CD19 ANTIGEN; CD8 ANTIGEN; COMPLEMENTARY DNA; CYTOKERATIN 19; FIBRONECTIN; MESSENGER RNA; PORPHOBILINOGEN DEAMINASE; TELOMERASE REVERSE TRANSCRIPTASE; THYROGLOBULIN; THYROTROPIN RECEPTOR; TUMOR MARKER; DIAGNOSTIC AGENT; DNA BINDING PROTEIN; KERATIN; LEUKOCYTE ANTIGEN; ONCOFETAL FIBRONECTIN; TELOMERASE;

ARTICLE; BLOOD CELL; CANCER DIAGNOSIS; CELL FRACTIONATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DIFFERENTIAL DIAGNOSIS; FLUORESCENCE; FOLLICULAR CARCINOMA; HUMAN; HUMAN TISSUE; LEUKOCYTE; MINIMAL RESIDUAL DISEASE; PAPILLARY CARCINOMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; THYROID CARCINOMA; ADENOCARCINOMA; BLOOD; CELL DIFFERENTIATION; COMPARATIVE STUDY; GENETICS; METABOLISM; THYROID TUMOR;

ADENOCARCINOMA, FOLLICULAR; ANTIGENS, CD; CARCINOMA, PAPILLARY; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; FIBRONECTINS; HUMANS; KERATINS; NEOPLASM, RESIDUAL; RECEPTORS, THYROTROPIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; TELOMERASE; THYROGLOBULIN; THYROID NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 26944441324     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602741     Document Type: Article

References (39)

1. Biscolla RP, Cerutti J, Maciel RM (2000) Detection of recurrent thyroid cancer by sensitive nested reverse transcription - polymerase chain reaction of thyroglobulin and sodium/iodide symporter messenger ribonucleic acid transcripts in peripheral blood. J Clin Endocrinol Metab 85: 3623-3627
2. Bojunga J, Roddiger S, Stanisch M, Kusterer K, Kurek R, Renneberg H, Adams S, Lindhorst E, Usadel KH, Schumm-Draeger PM (2000) Molecular detection of thyroglobulin mRNA transcripts in peripheral blood of patients with thyroid disease by RT-PCR. Br J Cancer 82: 1650-1655
3. Bugalho MJ, Domingues RS, Pinto AC, Garrao A, Catarino AL, Ferreira T, Limbert E, Sobrinho L (2001) Detection of thyroglobulin mRNA transcripts in peripheral blood of individuals with and without thyroid glands: evidence for thyroglobulin expression by blood cells. Eur J Endocrinol 145: 409-413
4. Burchill SA, Bradbury MF, Pittman K, Southgate J, Smith B, Selby P (1995) Detection of epithelial cancer cells in peripheral blood by reverse transcriptase - polymerase chain reaction. Br J Cancer 71: 278-281
5. Chelly J, Concordet JP, Kaplan JC, Kahn A (1989) Illegitimate transcription: transcription of any gene in any cell type. Proc Natl Acad Sci USA 86: 2617-2621
6. Chelly J, Hugnot JP, Concordet JP, Kaplan JC, Kahn A (1991) Illegitimate (or ectopic) transcription proceeds through the usual promoters. Biochem Biophys Res Commun 178: 553-557
7. Chinnappa P, Taguba L, Arciaga R, Faiman C, Siperstein A, Mehta AE, Reddy SK, Nasr C, Gupta MK (2004) Detection of thyrotropin-receptor messenger ribonucleic acid (mRNA) and thyroglobulin mRNA transcripts in peripheral blood of patients with thyroid disease: sensitive and specific markers for thyroid cancer. J Clin Endocrinol Metab 89: 3705-3709
8. Datta YH, Adams PT, Drobyski WR, Ethier SP, Terry VH, Roth MS (1994) Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction. J Clin Oncol 12: 475-482
9. de Kok JB, Zendman AJ, van de Locht LT, Ruers TJ, van Muijen GN, Mensink EJ, Swinkels DW (1999) Real-time hTERT quantification: a promising telomerase-associated tumor marker. Lab Invest 79: 911-912
10. Ditkoff BA, Marvin MR, Yemul S, Shi YJ, Chabot J, Feind C, Lo Gerfo PL (1996) Detection of circulating thyroid cells in peripheral blood. Surgery 120: 959-964, (discussion 964-965)
11. Elisei R, Vivaldi A, Agate L, Molinaro E, Nencetti C, Grasso L, Pinchera A, Pacini F (2004) Low specificity of blood thyroglobulin messenger ribonucleic acid assay prevents its use in the follow-up of differentiated thyroid cancer patients. J Clin Endocrinol Metab 89: 33-39
12. Eltahir EM, Mallinson DS, Birnie GD, Hagan C, George WD, Purushotham AD (1998) Putative markers for the detection of breast carcinoma cells in blood. Br J Cancer 77: 1203-1207
13. Eszlinger M, Neumann S, Otto L, Paschke R (2002) Thyroglobulin mRNA quantification in the peripheral blood is not a reliable marker for the follow-up of patients with differentiated thyroid cancer. Eur J Endocrinol 147: 575-582
14. Giannini R, Faviana P, Cavinato T, Elisei R, Pacini F, Berti P, Fontanini G, Ugolini C, Camacci T, De Ieso K, Miccoli P, Pinchera A, Basolo F (2003) Galectin-3 and oncofetal-fibronectin expression in thyroid neoplasia as assessed by reverse transcription - polymerase chain reaction and immunochemistry in cytologic and pathologic specimens. Thyroid 13: 765-770
15. Grammatopoulos D, Elliott Y, Smith SC, Brown I, Grieve RJ, Hillhouse EW, Levine MA, Ringel MD (2003) Measurement of thyroglobulin mRNA in peripheral blood as an adjunctive test for monitoring thyroid cancer. Mol Pathol 56: 162-166
16. Guller S, Ma Y, Raju U, Kadner S, Thung SF, Colasacco L, Malek A, Schneider H (2003) Release of oncofetal fibronectin from human placenta. Placenta 24: 843-850
17. Holt SE, Shay JW (1999) Role of telomerase in cellular proliferation and cancer. J Cell Physiol 180: 10-18
18. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015
19. Li D, Butt A, Clarke S, Swaminathana R (2004) Real-time quantitative PCR measurement of thyroglobulin mRNA in peripheral blood of thyroid cancer patients and healthy subjects. Ann N Y Acad Sci 1022: 147-151
20. Lichtinghagen R, Diedrich-Glaubitz R, von Horsten B (1994) Identification of Bordetella pertussis in nasopharyngeal swabs using the polymerase chain reaction: evaluation of detection methods. Eur J Clin Chem Clin Biochem 32: 161-167
21. Lichtinghagen R, Helmbrecht T, Arndt B, Boker KH (1995) Expression pattern of matrix metalloproteinases in human liver. Eur J Clin Chem Clin Biochem 33: 65-71
22. Mazzaferri EL (2000) Long-term outcome of patients with differentiated thyroid carcinoma: effect of therapy. Endocr Pract 6: 469-476
23. Musholt PB, Imkamp F, von Wasielewski R, Schmid KW, Musholt TJ (2003) RET rearrangements in archival oxyphilic thyroid tumors: new insights in tumorigenesis and classification of Hurthle cell carcinomas? Surgery 134: 881-889, (discussion 889)
24. Parker SL, Tong T, Bolden S, Wingo PA (1997) Cancer statistics, 1997. CA Cancer J Clin 47: 5-27
25. Pedersen IB, Knudsen N, Jorgensen T, Perrild H, Ovesen L, Laurberg P (2003) Thyroid peroxidase and thyroglobulin autoantibodies in a large survey of populations with mild and moderate iodine deficiency. Clin Endocrinol (Oxf) 58: 36-42
26. Ringel MD, Balducci-Silano PL, Anderson JS, Spencer CA, Silverman J, Sparling YH, Francis GL, Burman KD, Wartofsky L, Ladenson PW, Levine MA, Tuttle RM (1999) Quantitative reverse transcription-polymerase chain reaction of circulating thyroglobulin messenger ribonucleic acid for monitoring patients with thyroid carcinoma. J Clin Endocrinol Metab 84: 4037-4042
27. Ringel MD, Ladenson PW, Levine MA (1998) Molecular diagnosis of residual and recurrent thyroid cancer by amplification of thyroglobulin messenger ribonucleic acid in peripheral blood. J Clin Endocrinol Metab 83: 4435-4442
28. Soria JC, Gauthier LR, Raymond E, Granotier C, Morat L, Armand JP, Boussin FD, Sabatier L (1999) Molecular detection of telomerase-positive circulating epithelial cells in metastatic breast cancer patients. Clin Cancer Res 5: 971-975
29. Span PN, Sleegers MJ, van den Broek WJ, Ross HA, Nieuwlaat WA, Hermus AR, Sweep CG (2003) Quantitative detection of peripheral thyroglobulin mRNA has limited clinical value in the follow-up of thyroid cancer patients. Ann Clin Biochem 40: 94-99
30. Spencer CA, Takeuchi M, Kazarosyan M, Wang CC, Guttler RB, Singer PA, Fatemi S, LoPresti JS, Nicoloff JT (1998) Serum thyroglobulin autoantibodies: prevalence, influence on serum thyroglobulin measurement, and prognostic significance in patients with differentiated thyroid carcinoma. J Clin Endocrinol Metab 83: 1121-1127
31. Takano T, Matsuzuka F, Liu G, Miyauchi A, Yokozawa T, Kuma K, Amino N (1999) Analysis of splice variants of the fibronectin gene in thyroid carcinomas by reverse transcription - polymerase chain reaction: increased expression of oncofetal fibronectin mRNA in papillary carcinomas is not caused by the alternation in splicing. J Endocrinol Invest 22: 18-22
32. Takano T, Matsuzuka F, Sumizaki H, Kuma K, Amino N (1997) Rapid detection of specific messenger RNAs in thyroid carcinomas by reverse transcription - PCR with degenerate primers: specific expression of oncofetal fibronectin messenger RNA in papillary carcinoma. Cancer Res 57: 3792-3797
33. Takano T, Miyauchi A, Matsuzuka F, Kuma K, Amino N (2000) Expression of oncofetal fibronectin messenger ribonucleic acid in fibroblasts in the thyroid: a possible cause of false positive results in molecular-based diagnosis of thyroid carcinomas. J Clin Endocrinol Metab 85: 765-768
34. Takano T, Miyauchi A, Yoshida H, Hasegawa Y, Kuma K, Amino N (2001) Quantitative measurement of thyroglobulin mRNA in peripheral blood of patients after total thyroidectomy. Br J Cancer 85: 102-106
35. Tallini G, Ghossein R, Emanuel J, Gill J, Kinder B, Dimich AB, Costa J, Robbins R, Burrow GN, Rosai J (1998) Detection of thyroglobulin, thyroid peroxidase, and RET/PTC1 mRNA transcripts in the peripheral blood of patients with thyroid disease. J Clin Oncol 16: 1158-1166
36. Trummer A, Kadar J, Arseniev L, Petersen D, Ganser A, Lichtinghagen R (2000) Competitive cytokeratin 19 RT-PCR for quantification of breast cancer cells in blood cell suspensions. J Hematother Stem Cell Res 9: 275-284
37. Verburg FA, Lips CJ, Lentjes EG, de Klerk JM (2004) Detection of circulating Tg-mRNA in the follow-up of papillary and follicular thyroid cancer: how useful is it? Br J Cancer 91: 200-204
38. Weber T, Lacroix J, Weitz J, Amnan K, Magener A, Holting T, Klar E, Herfarth C, von Knebel Doeberitz M (2000) Expression of cytokeratin 20 in thyroid carcinomas and peripheral blood detected by reverse transcription polymerase chain reaction. Br J Cancer 82: 157-160
39. Wingo ST, Ringel MD, Anderson JS, Patel AD, Lukes YD, Djuh YY, Solomon B, Nicholson D, Balducci-Silano PL, Levine MA, Francis GL, Tuttle RM (1999) Quantitative reverse transcription - PCR measurement of thyroglobulin mRNA in peripheral blood of healthy subjects. Clin Chem 45: 785-789