Molecular detection of telomerase-positive circulating epithelial cells in metastatic breast cancer patients

Clinical Cancer Research

Volumn 5, Issue 5, 1999, Pages 971-975

  Soria, Jean Charles ^a,b   Gauthier, Laurent R ^a   Raymond, Eric ^b   Granotier, Christine ^a   Morat, Luc ^a   Armand, Jean Pierre ^b   Boussin, François D ^a   Sabatier, Laure ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

ARTICLE; BREAST CANCER; CANCER STAGING; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; PROGNOSIS;

ADULT; AGED; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DNA, NEOPLASM; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FEMALE; HUMANS; IMMUNOMAGNETIC SEPARATION; MIDDLE AGED; NEOPLASM CIRCULATING CELLS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASM STAGING; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TELOMERASE; TUMOR MARKERS, BIOLOGICAL; TUMOR STEM CELLS;

EID: 0032926781     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Hudis, C. A., and Norton, L. Adjuvant drug therapy for operable breast cancer. Oncology, 23: 475-493, 1996.
2. McCulloch, P., Choy, A., and Martin, L. Association between tumour angiogenesis and tumour cell shedding into effluent venous blood during breast cancer surgery. Lancet, 346: 1334-1335, 1995.
3. Diel, I. J., Kaufmann, M., Goerner, R., Costa, S. D., Kaul, S., and Bastert, G. Detection of tumor cells in bone marrow of patients with primary breast cancer: a prognostic factor for distant metastasis. J. Clin. Oncol., 10: 1534-1539, 1992.
4. Eltahir, E. M., Mallinson, D. S., Birnie, G. D., Hagan, C., George, W. D., and Purushotham, A. D. Putative markers for the detection of breast carcinoma cells in blood. Br. J. Cancer, 77: 1203-1207, 1998.
5. Ghossein, R. A., and Rosai, J. Polymerase chain reaction in the detection of micrometastases and circulating tumor cells. Cancer (Phila.), 78: 10-16, 1996.
6. Shay, J. W., and Gazdar, A. F. Telomerase in the early detection of cancer. J. Clin. Pathol., 50: 106-109, 1997.
7. Hiyama, E., Hiyama, K., Yokoyama, T., Matsuura, Y., Piatyszek, M. A., and Shay, J. W. Correlating telomerase activity levels with human neuroblastoma outcomes. Nat. Med., 1: 249-257, 1995.
8. Shay, J. W., and Bacchetti, S. A survey of telomerase activity in human cancer. Eur. J. Cancer, 33: 787-791, 1997.
9. Clark, G. M., Osbornr, C. K., Levitt, D., Wu, F., and Kim, N. W. Telomerase activity and survival of patients with node positive breast cancer. J. Natl. Cancer Inst. (Bethesda), 89: 1874-1881, 1997.
10. Langford, L. A., Piatyszek, M. A., Xu, R., Schold, S. C., Wright, W. E., and Shay, J. W. Telomerase activity in ordinary meningiomas predicts poor outcome. Hum. Pathol., 28: 416-420, 1997.
11. Hiyama, E., Gollahon, L., Kataoka, T., Kuroi, K., Yokoyama, T., Gazdar, A. F., Hiyama, K., Piatyszek, M. A., and Shay, J. W. Telomerase activity in human breast tumors. J. Natl. Cancer Inst. (Bethesda), 88: 116-122, 1996.
12. Sugino, T., Yoshida, K., Bolodeoku, J., Tahara, H., Buley, I., Manek, S., Wells, C., Goodison, S., Ide, T., Suzuki, T., Tahara, E., and Tarin, D. Telomerase activity in human breast cancer and benign breast lesions: diagnosis applications in clinical specimens, including fine needle aspirates. Int. J. Cancer, 69: 301-306, 1996.
13. Villa, R., Zaffaroni, N., Folini, M., Martelli, G., De Palo, G., Daidone, M., and Silvestrini R. Telomerase activity in benign and malignant breast lesions: a pilot prospective study on fine-needle aspirates. J. Natl. Cancer Inst. (Bethesda), 90: 537-539, 1998.
14. Carey, L. A, Hedican, C. A., Henderson, G. S., Umbricht, C. B., Dome, J. S., Varon, D., and Sukumar, S. Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers. Clin. Cancer Res., 4: 435-440, 1998.
15. Larza, U., Niedobitek, G., Schwarting, R., Nekarda, H., and Stein, H. Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelia. J. Clin. Pathol., 43: 213-219, 1990.
16. Koyanagi, K., Ozawa, S., Ando, N., Kitagawa, Y., Takeuchi, H., and Ueda, M. Clinical significance of telomerase activity in peripheral blood from the patients with squamous cell carcinoma of the esophagus. Proc. Am. Assoc. Cancer Res., 39: 350, 1998.
17. Weng, N. P., Levine, B. L., June, C. H., and Hodes, R. J. Regulated expression of telomerase activity in human T lymphocyte development and activation. J. Exp. Med., 183: 2471-2479, 1996.
18. Iwama, H., Ohyashiki, K., Ohyashiki, J. H., Hayashi, S., Yahata, N., Ando, K., Toyama, K., Hoshika, A., Takasaki, M., Mori, M., and Shay, J. W. Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Hum. Genet., 102: 397-402, 1998.
19. -7. Proc. Natl. Acad. Sci. USA, 92: 537-541, 1995.
20. Schoenfeld, A., Kruger, K. H., Gomm, J., Sinnett, H. D., Gazet, J. C., Sacks, N., Bender, H. G., Luqmani, Y., and Coombes, R. C. The detection of micrometastases in the peripheral blood and bone marrow of patients with breast cancer using immunohistochemistry and reverse transcriptase polymerase chain reaction for keratin 19. Eur. J. Cancer, 6: 854-861, 1997.
21. Hardingham, J. E., Kotasek, D., Farmer, B., Butler, R. N., and Mi, J. X. Immunobead-PCR: a technique for the detection of circulating tumor cells using immunomagnetic beads and the polymerase chain reaction. Cancer Res., 53: 3455-3458, 1993.
22. Racila, E., Euhus, D., Weiss, A. J., Rao, C., McConnell, J., Terstappen, L. W., and Uhr, J. W. Detection and characterization of carcinoma cells in the blood. Proc. Natl. Acad. Sci., 95: 4589-4594, 1998.
23. Faraoni, I., Turriziani, M., Masci, G., De Vecchis, L., Shay, J. W., Bonmassar, E., and Graziani, G. Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro. Clin. Cancer Res., 3: 579-585, 1997.
24. Engelhard, M., Ozkaynak, M. F., Drullinsky, P., Sandoval, C., Tugal, O., Jayabose, S., and Moore, M. A. Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy. Leukemia (Baltimore), 12: 13-24, 1998.