Serum thyroglobulin autoantibodies: Prevalence, influence on serum thyroglobulin measurement, and prognostic significance in patients with differentiated thyroid carcinoma

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 4, 1998, Pages 1121-1127

  Spencer, C A ^a   Takeuchi, M ^a   Kazarosyan, M ^a   Wang, C C ^b   Guttler, R B ^c   Singer, P A ^a   Fatemi, S ^d   Lopresti, J S ^a   Nicoloff, J T ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c S Monica Thyroid Diagnostic Center   (United States)

^d KAISER PERMANENTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; THYROGLOBULIN; THYROGLOBULIN ANTIBODY; THYROID PEROXIDASE;

ADOLESCENT; ADULT; AGED; ANTIBODY BLOOD LEVEL; ARTICLE; CHILD; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOASSAY; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; RADIOIMMUNOASSAY; THYROID CARCINOMA; TUMOR DIFFERENTIATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AUTOANTIBODIES; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; CHILD; FEMALE; HEMAGGLUTINATION TESTS; HUMANS; IMMUNORADIOMETRIC ASSAY; INFANT; MALE; MIDDLE AGED; PREVALENCE; PROGNOSIS; RADIOIMMUNOASSAY; REFERENCE VALUES; SEX CHARACTERISTICS; THYROGLOBULIN; THYROID NEOPLASMS;

IMA;

EID: 0031791032     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.4.1121     Document Type: Article

References (36)

1. Van Herle AJ, Uller RP. 1975 Elevated serum thyroglobulin: a marker of metastases in differentiated thyroid carcinomas. J Clin Invest. 56:272-277.
2. Spencer CA, Wang CC. 1995 Thyroglobulin measurement: techniques, clinical benefits and pitfalls. Endocrinol Metab Clin North Am. 24:841-863.
3. Spencer CA, Takeuchi M, Kazarosyan M. 1996 Current status and performance goals for serum thyroglobulin assays. Clin Chem. 42:164-173.
4. Feldt-Rasmussen U, Profilis C, Colinet E, Schlumberger M, Black E. 1994 Purification and assessment of stability and homogeneity of human thyroglobulin reference material (CRM 457). Exp Clin Endocrinol. 102:87-91.
5. Feldt-Rasmussen U, Profilis C, Colinet E, et al. 1996 Human thyroglobulin reference material (CRM 457) 1st part: assessment of homogeneity, stability and immunoreactivity. Ann Biol Clin. 54:337-342.
6. Roitt IM, Torrigiani G. 1967 Identification and estimation of undegraded thyroglobulin in human serum. Endocrinology. 81:421-429.
7. Schneider AB, Pervos R. 1978 Radioimmunoassay of human thyroglobulin: effect of antithyroglobulin autoantibodies. J Clin Endocrinol Metab. 47:126-137.
8. Mariotti S, Barbesino G, Caturegli P, et al. 1995 Assay of thyroglobulin in serum with thyroglobulin autoantibodies: an unobtainable goal? J Clin Endocrinol Metab. 80:468-472.
9. Spencer CA, Platler B, Guttler RB, Nicoloff JT. 1985 Heterogeneity of 125-I labelled thyroglobulin preparations. Clin Chim Acta. 151:121-132.
10. Spencer CA, Platler BW, Nicoloff JT. 1985 The effect of 125-I thyroglobulin tracer heterogeneity on serum Tg RIA measurement. Clin Chim Acta. 153:105-115.
11. Black EG, Hoffenberg R. 1983 Should one measure serum thyroglobulin in the presence of anti-thyroglobulin antibodies? Clin Endocrinol (Oxf). 19:597-601.
12. Black EG, Cassoni A, Gimlette TMD, et al. 1981 Serum thyroglobulin in thyroid cancer. Lancet. 2:443-445.
13. Black EG, Sheppard MC, Hoffenberg R. 1987 Serial serum thyroglobulin measurements in the management of differentiated thyroid carcinoma. Clin Endocrinol (Oxf). 27:115-120.
14. Black EG, Sheppard MC. 1991 Serum thyroglobulin measurements in thyroid cancer: evaluation of 'false' positive results. Clin Endocrinol (Oxf). 35:519-520.
15. Ericsson UB, Christensen SB, Thorell JI. 1985 A high prevalence of thyroglobulin autoantibodies in adults with and without thyroid disease as measured with a sensitive solid-phase immunosorbent radioassay. Clin Immunol Immunopathol. 37:154-162.
16. Kumar A, Shah Dh, Shrihari U, Dandekar SR, Vijayan U, Sharma SM. 1994 Significance of antithyroglobulin autoantibodies in differentiated thyroid carcinoma. Thyroid. 4:199-202.
17. Preissner CM, Klee GG, Krco CJ. 1988 Nonisotopic "sandwich" immunoassay of thyroglobulin in serum by the biotin-streptavidin technique: evaluation and comparison with an immunoradiometric assay. Clin Chem. 34:1794-1798.
18. Matsubayashi S, Kawai K, Matsumoto Y, et al. 1995 The correlation between papillary thyroid carcinoma and lymphocytic infiltration in the thyroid gland. J Clin Endocrinol Metab. 80:3421-3424.
19. Schneider A, Ikekubo K, Kuma K. 1983 Iodine content of serum thyroglobulin in normal individuals and patients with thyroid cancer. J Clin Endocrinol Metab. 57:1251-1256.
20. Pacini F, Mariotti S, Formica N, Elisei R. 1988 Thyroid autoantibodies in thyroid cancer: Incidence and relationship with tumor outcome. Acta Endocrinol (Copenh). 119:373-380.
21. Rubello D, Girelli ME, Casara D, Piccolo M, Perin A, Busnardo B. 1990 Usefulness of the combined antithyroglobulin antibodies and thyroglobulin assay in the follow-up of patients with differentiated thyroid cancer. J Endocrinol Invest. 13:737-742.
22. Rubello D, Casara D, Girelli ME, Piccolo M, Busnardo B. 1992 Clinical meaning of circulating antithyroglobulin antibodies in differentiated thyroid cancer: a prospective study. J Nucl Med. 33:1478-1480.
23. Feldt-Rasmussen U, Schlumberger M. 1988 European interlaboratory comparison of serum thyroglobulin measurement. J Endocrinol Invest. 11:175-181.
24. Zucchelli GC, Pilo A, Masini S, Prontera C, Ferdeghini M. 1996 Large between-laboratory variability of thyroglobulin immunoassays: data collected in a collaborative study. J Clin Ligand Assay. 19:234-238.
25. Ligabue A, Poggioli MC, Zacchini A. 1993 Interference of specific autoantibodies in the assessment of serum thyroglobulin. J Nucl Biol Med. 37:273-279.
26. Bayer M, Kriss JP. 1979 A solid phase, sandwich-type radioimmunoassay for antithyroglobulin: elimination of false positive results and semiquantitative measurement of antithyroglobulin in the presence of elevated thyroglobulin. J Clin Endocrinol Metab. 49:565-571.
27. Erali M, Bigelow Rb, Meikle AW. 1996 ELISA for thyroglobulin in serum: recovery studies to evaluate autoantibody interference and reliability of thyroglobulin values. Clin Chem. 42:766-770.
28. Rodbard D. 1977 "Specific" interference (parallel displacement) in radioligand assays by extraneous binding proteins. Endocrinology. 101:1180-1183.
29. Mariotti S, Cupini C, Giani C, et al. 1982 Evaluation of a solid-phase immunoradiometric assay (IRMA) for serum thyroglobulin: effect of anti-thyroglobulin autoantibody. Clin Chim Acta. 123:347-355.
30. Schlumberger M, Tubiana M, De Vathaire F, et al. 1986 Long-term results of treatment of 283 patients with lung and bone metastases from differentiated thyroid carcinoma. J Clin Endocrinol Metab. 63:960-967.
31. Schaadt B, Feldt-Rasmussen U, Rasmussen B, et al. 1995 Assessment of the influence of thyroglobulin (Tg) autoantibodies and other interfering factors on the use of serum Tg as tumor marker in differentiated thyroid carcinoma. Thyroid. 5:165-170.
32. Spencer CA. 1996 Recoveries cannot be used to authenticate thyroglobulin (Tg) measurements when sera contain Tg autoantibodies. Clin Chem. 42:661-663.
33. Schulz R, Bethauser H, Stempka L, Heilig B, Moll A, Hufner M. 1989 Evidence for immunological differences between circulating and tissue-derived thyroglobulin in men. Eur J Clin Invest. 19:459-463.
34. Piechaczyk M, Baldet L, Pau B, Bastide JM. 1989 Novel immunoradiometric assay of thyroglobulin in serum with use of monoclonal antibodies selected for lack of cross-reactivity with autoantibodies. Clin Chem. 35:422-424.
35. Ruf J, Carayon P, Lissitzky S. 1985 Various expressions of a unique antihuman thyroglobulin antibody repertoire in normal state and autoimmune disease. Eur J Immunol. 15:268-272.
36. Weigle WO, High GJ. 1967 The behaviour of autologous thyroglobulin in the circulation of rabbits immunized with either heterologous or altered homologous thyroglobulin. J Immunol. 98:1105-1114.