Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats

Hepatology Research

Volumn 33, Issue 1, 2005, Pages 50-56

  Qin, Li Qiang ^a   Wang, Pei Yu ^b   Wang, Yuan ^c   Kaneko, Takashi ^a   Hoshi, Kazuhiko ^a   Sato, Akio ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Acetaminophen (APAP); Carbon tetrachloride (CCl4); Cytochrome P450 2E1 (CYP2E1); Hepatotoxicity; Voglibose

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; GLUTATHIONE; MALONALDEHYDE; PARACETAMOL; VOGLIBOSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; IN VIVO STUDY; LIVER METABOLISM; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

EID: 26844486245     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hepres.2005.08.002     Document Type: Article

References (44)

1. S. Horii H. Fukase T. Matsuo Y. Kameda N. Asano K. Masui Synthesis and α- d -glucosidase inhibitory activity of N-substituted valiolamine derivatives as potent oral antidiabetic agents J Med Chem 29 1987 1038-1046
2. B. Göke H. Fuder G. Wieckhorst et al. Voglibose (AO-128) is an efficient α-glucosidase inhibitor and mobilizes the endogenous GLP-1 reserve Digestion 56 1995 493-501
3. H. Odaka T. Matsuo Effect of a disacchridese inhibitor, AO-128, on post-prandial hyperglycemia in rats J Jpn Soc Nutr Food Sci 45 1992 27-31
4. T. Matsuo H. Odaka H. Ikeda Effect of an intestinal disacchridase inhibitor (AO-128) on obexity and diabetes Am J Clin Nutr 55 1992 314S-317S
5. P. Kleist Y. Suzuki T. Thomsen et al. Voglibose has no effect on the pharmacokinetics of hydrochlorothiazide Eur J Clin Pharmacol 54 1998 273-274
6. S. Okada K. Ishii S. Tanokuchi H. Hamada K. Ichiki Z. Ota Effect of an α-glucosidase inhibitor combined with sulphonylurea treatment on glucose metabolism in patients with non-insulin-dependent diabetes mellitus J Int Medical Res 23 1995 279-283
7. H. Odaka A. Shino H. Ikeda T. Matsuo Antibesity and antidiabetic actions of a new potent disaccharidase inhibitor in genetically obese-diabetic mice, KKA J Nutr Sci Vitaminol 38 1992 27-37
8. A. Vichayanrat S. Ploybutr M. Tunlakit P. Watanakejorn Efficacy and safety of voglibose in comparison with acarbose in type 2 diabetic patients Diabetes Res Clin Pr 55 2002 99-103
9. Baba S. Characteristics of the α-glucosidase inhibitor. in: Baba, S., Editor. Diabetes: Focus on α-glucosidase inhibitor. International trends in drug treatment. Japan: Churchill Livingstone; 1994. p. 20-34.
10. T. Matsumoto M. Ishikawa Y. Yamauchi et al. Drug-induced hepatitis with severe cholestasis due to voglibose Int Hepatol Commun 5 1996 289-296
11. S. Kawakami T. Arima K. Harada et al. Hepatic necrosis with cholestasis induced by long-term voglibose administration Internal Med 40 2001 484-488
12. Pharmaceuticals and Medical Device Agency. http://www.info.pmda.go.jp/fukusayou/menu_fukusayou_attention.htm
13. M. Boll L. Weber E. Becker A. Stampfl Mechanism of carbon tetrachloride-induced hepatotoxicity. Hepatocellular damage by reactive carbon tetrachloride metabolites Z Naturforsch 56c 2001 649-659
14. H.D. Conner R.G. Thurman M.D. Galizi R.P. Mason The information of a novel free radical metabolite from CCl4 in the perfused rat liver and in vivo J Biol Chem 261 1986 4542-4548
15. M.Q. Bromer M. Black Acetaminophen hepatotoxicity Clin Liver Dis 7 2003 351-367
16. C.H. Florén P. Thesleff A. Nilsson Severe liver damage caused by therapeutic doses of acetaminophen Acta Med Scand 222 1987 285-288
17. F.V. Schiødt F.A. Rochling D.L. Casey W.M. Lee Acetaminophen toxicity in an urban county hospital N Engl J Med 337 1997 1112-1117
18. P.Y. Wang T. Kaneko Y. Wang A. Sato Acarbose alone or in combination with ethanol potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen in rats Hepatology 29 1999 161-165
19. J. Li T. Kaneko Y. Wang L.Q. Qin P.Y. Wang A. Sato Troglitazone enhances the hepatotoxicity of acetaminophen by inducing CYP3A in rats Toxicology 176 2002 91-100
20. A. Plewka B. Zielinska-Psuja J. Kowalowka-Zawieja et al. Influence of acetaminophen and trichloroethylene on liver cytochrome P450-dependent monooxygenase system Acta Biochimica Polonica 47 2000 1129-1136
21. C.S. Lieber CYP2E1: From ASH to NASH Hepatology Res 28 2004 1-11
22. G.L. Ellman Tissue sulfhydryl group Arch Biochem Biophys 82 1959 70-77
23. O.H. Lowry N.J. Rosebrough A.L. Farr R.J. Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265-275
24. T. Omura R. Sato The carbon monoxide-binding pigment of liver microsomes. 1 Evidence for its hemoprotein nature J Biol Chem 239 1964 2370-2378
25. H. Towbin T. Staehelin J. Gordon Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications Proc Natl Acad Sci USA 76 1979 4350-4354
26. M.H. Court L.L. Von Moltke R.I. Shader D.J. Greenblatt Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species Biopharm Drug Dispos 18 1997 213-226
27. M.D. Burke S. Thompson C.R. Elcombe J. Halpert T. Haaparanta R.T. Mayer Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450 Biochem Pharmacol 34 1985 3337-3345
28. M. Mitcheva H. Astroug D. Drenska A. Popov M. Kassarova Biochemical and morphological studies on the effects of anthocyans and vitamine E on carbon tetrachloride induced liver injury Cell Mol Biol 39 1993 443-448
29. A. Watanabe H. Nagashima Glutathione metabolism and glucose-6-phosphate dehydrogenase activity in experimental liver injury Acta Med Okayama 37 1983 463-470
30. M. Black Acetaminophen hepatotoxicity Gastroenterology 78 1980 382-392
31. O. Arouma B. Halliwell M. Laughton G. Quinatan J. Glutteridge The mechanism of initiation of lipid peroxidation. Evidence against a requirement for an iron (II) and iron (III) complex Biochemical J 258 1989 617-620
32. T. Nakajima Y. Koyama A. Sato Dietary modification of metabolism and toxicity of chemical substances-with special reference to carbohydrate Biochem Pharmacol 31 1982 1005-1011
33. D.C. Whitcomb G.D. Block Association of acetaminophen hepatotoxicity with fasting and ethanol use JAMA 272 1994 1845-1850
34. J. Hong J. Pan F.J. Gonzalez H.V. Gelboin C.S. Yang The induction of a specific form of cytochrome P-450 (P-450j) by fasting Biochem Biophys Res Commun 142 1987 1077-1083
35. O.G. Khatsenko R.K. Sindhu Y. Kikkawa Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver Arch Toxicol 71 1997 684-689
36. T.F. Slater Necrogenic action of carbon tetrachloride in the tar: A speculative mechanism based on activation Nature 209 1996 36040
37. P.Y. Wang T. Kaneko H. Tsukada M. Nakano T. Nakajima A. Sato Time courses of hepatic injuries induced by chloroform and by carbon tetrachloride: Comparison of biochemical and histopathological changes Arch Toxicol 71 1997 638-645
38. M. Manno F. De Matteis L.J. King The mechanism of the suicidal, reductive inactivation of microsomal cytochrome P-450 by carbon tetrachloride Biochem Pharamcol 37 1988 1981-1990
39. K. Yokogawa M. Watanabe H. Takeshita M. Nomura Y. Mano K. Miyamoto Serum aminotransferase activity as a predictor of clearance of drugs metabolized by CYP isoforms in rats with acute hepatic failure induced by carbon tetrachloride Int J Pharm 269 2004 479-489
40. M.C. Savides F.W. Oehme Acetaminophen and its toxicity J Appl Toxicol 3 1983 96-111
41. J. Sinclair E. Jeffery S. Wrighton et al. Alcohol-mediated increases in acetaminophen hepatotoxicity: Role of CYP2E and CYP3A Biochem Pharmacol 55 1998 1557-1565
42. H. Zaher J.T. Buters J.M. Ward et al. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice Toxicol Appl Pharm 152 1998 193-199
43. E. Hazai L. Vereczkey K. Monostory Reduction of toxic metabolite formation of acetaminophen Biochem Bioph Res Co 291 2002 1089-1094
44. P.T. Manyike E.D. Kharasch T.F. Kalhorn J.T. Slattery Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation Clin Pharmacol Ther 67 2000 275-282