Characterization of advanced glycation end products: Mass changes in correlation to side chain modifications

Analytical Biochemistry

Volumn 346, Issue 1, 2005, Pages 101-106

  Schmitt, Annett ^a   Gasic Milenkovic, Jovana ^a   Schmitt, Johannes ^b  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b NIMBUS Biotechnologie GmbH   (Germany)

Author keywords

Advanced glycation end products; AGE characterization; Mass spectrometry; Side chain modification

Indexed keywords

AMINO ACIDS; DESORPTION; FLUORESCENCE; GLYCOSYLATION; MOLECULAR MASS; PROTEINS;

ADVANCED GLYCATION END PRODUCTS; DEGREE OF MODIFICATION; FLUORESCENCE CHARACTERISTICS; FORMATION KINETICS; HUMAN SERUM ALBUMINS; MASS SPECTROMETRIC DATA; MATRIX-ASSISTED LASER DESORPTION/IONIZATION-TIME-OF-FLIGHT MASS SPECTROMETRY; SIDE CHAIN MODIFICATIONS;

MASS SPECTROMETRY;

ADVANCED GLYCATION END PRODUCT; ARGININE; GLUCOSE; GLYOXYLIC ACID; HUMAN SERUM ALBUMIN; LYSINE;

ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; CORRELATION ANALYSIS; FLUORESCENCE; HUMAN; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL;

EID: 26844441767     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2005.07.035     Document Type: Article

References (12)

1. P.J. Thornalley Cell activation by glycated proteins: AGE receptors, receptor recognition factors, and functional classification of AGEs Cell. Mol. Biol. 44 1998 1013 1023
2. R. Bucala, Z. Makita, G. Vega, S. Grundy, T. Koschinsky, A. Cerami, and H. Vlassara Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency Proc. Natl. Acad. Sci. USA 91 1994 9441 9445
3. M.P. Vitek, K. Bhattacharya, J.M. Glendening, E. Stopa, H. Vlassara, R. Bucala, K. Manogue, and A. Cerami Advanced glycation end products contribute to amyloidosis in Alzheimer's disease Proc. Natl. Acad. Sci. USA 91 1994 4766 4770
4. A. Schmitt, J. Schmitt, G. Münch, and J. Gasic-Milencovic Characterization of advanced glycation end products for biochemical studies: side chain modifications and fluorescence characteristics Anal. Biochem. 338 2005 201 215
5. R.E. Smith, and R. MacQuarrie A sensitive fluorometric method for the determination of arginine using 9,10-phenanthrenequinone Anal. Biochem. 90 1978 246 255
6. S.D. Sharma, B.N. Pandey, K.P. Mishra, and S. Sivakami Amadori product and age formation during nonenzymatic glycosylation of bovine serum albumin in vitro J. Biochem. Mol. Biol. Biophys. 6 2002 233 242
7. T.W. Lo, M.E. Westwood, A.C. McLellan, T. Selwood, and P.J. Thornalley Binding and modification of proteins by methylglyoxal under physiological conditions: a kinetic and mechanistic study with N-α-acetylarginine, N-α-acetylcysteine, N-α-acetyllysine, and bovine serum albumin J. Biol. Chem. 269 1994 32299 32305
8. R.H. Nagaraj, I.N. Shipanova, and F.M. Faust Protein cross-linking by the Maillard reaction: isolation, characterization, and in vivo detection of a lysine-lysine cross-link derived from methylglyoxal J. Biol. Chem. 271 1996 19338 19345
9. T.D. Lehman, and B.J. Ortwerth Inhibitors of advanced glycation end product-associated protein cross-linking Biochim. Biophys. Acta 1535 2001 110 119
10. D. Slowik-Zylka, K. Safranow, V. Dziedziejko, H. Bukowska, K. Ciechanowski, and D. Chlubek A sensitive and specific HPLC method for the determination of total pentosidine concentration in plasma J. Biochem. Biophys. Methods 61 2004 313 329
11. S.C. Wilker, P. Chellan, B.M. Arnold, and R.H. Nagaraj Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine Anal. Biochem. 290 2001 353 358
12. P.J. Thornalley, A. Langborg, and H.S. Minhas Formation of glyoxal, methylglyoxal, and 3-deoxyglucosone in the glycation of proteins by glucose Biochem. J. 344 1999 109 116