The boron-neutron capture agent β-D-5-o-carboranyl- 2′-deoxyuridine accumulates preferentially in dividing brain tumor cells

Journal of Neuro-Oncology

Volumn 74, Issue 3, 2005, Pages 275-280

  Moore, Casey ^a   Hernández Santiago, Brenda I ^b   Hurwitz, Selwyn J ^b   Tan, Chalet ^b   Wang, Chris ^a   Schinazi, Raymond F ^b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Boron neutron capture therapy; Cell cycle; Glioma; Nucleosides

Indexed keywords

BETA DEXTRO 5,2 CARBORANYL 2' DEOXYURIDINE; BORON 10; DRUG METABOLITE; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BLOOD BRAIN BARRIER; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL SYNCHRONIZATION; CONTROLLED STUDY; DOSIMETRY; DRUG ACCUMULATION; DRUG SYNTHESIS; GLIOMA; GLIOMA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPOTHESIS; NEUTRON CAPTURE THERAPY; PHOSPHORYLATION;

BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYURIDINE; FLOW CYTOMETRY; GLIOMA; HUMANS; RADIATION-SENSITIZING AGENTS;

EID: 26844433976     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-004-8323-y     Document Type: Article

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