Synthesis of 5-(1-propynyl)-2′-deoxyuridine 5′-(alpha-P-borano) triphosphate and kinetic characterization as a substrate for MMLV reverse transcriptase

Nucleosides, Nucleotides and Nucleic Acids

Volumn 24, Issue 5-7, 2005, Pages 947-950

  Wang, Joy Xin ^a   Shaw, Barbara Ramsay ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

5 ( P Borano) Triphosphates; Boranophosphate; C5 Propynyl Pyrimidines; MMLV Reverse Transcriptase; Oligodeoxyribonucleotide Analogs; Steady State Kinetics

Indexed keywords

5 (1 PROPYNYL) 2' DEOXYURIDINE 5' (ALPHA PHOSPHOBORANO)TRIPHOSPHATE; DEOXYURIDINE DERIVATIVE; OLIGODEOXYRIBONUCLEOTIDE; PRIMER DNA; PYRIMIDINE; RNA DIRECTED DNA POLYMERASE; THYMIDINE TRIPHOSPHATE; UNCLASSIFIED DRUG;

CHEMICAL REACTION KINETICS; CONFERENCE PAPER; DIASTEREOISOMER; DNA TEMPLATE; MASS SPECTROMETRY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; SYNTHESIS; ULTRAVIOLET RADIATION;

BORON; BORON COMPOUNDS; DNA; DNA PRIMERS; HIV-1 REVERSE TRANSCRIPTASE; KINETICS; MODELS, CHEMICAL; MOLONEY MURINE LEUKEMIA VIRUS; NUCLEOTIDES; OLIGONUCLEOTIDES; POLYPHOSPHATES; PROTEIN ISOFORMS; PYRIMIDINES; RNA-DIRECTED DNA POLYMERASE; THYMIDINE; THYMINE NUCLEOTIDES; URIDINE; URIDINE TRIPHOSPHATE;

EID: 26644453965     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1081/NCN-200059307     Document Type: Conference Paper

References (11)

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