Maspin and the order of signaling

Cancer Biology and Therapy

Volumn 2, Issue 4, 2003, Pages 404-405

  Sheng, Shijie ^a  

^a NONE

Author keywords

Adhesion; Breast cancer; Cell matrix interaction; Motility; PI3K; Rac1 and small GTP binding proteins; Serine protease inhibitor; Tumor suppressor

Indexed keywords

MASPIN; PROTEIN; SERINE PROTEINASE INHIBITOR;

BREAST TUMOR; CELL ADHESION; CELL MOTION; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; NOTE; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CELL ADHESION; CELL MOVEMENT; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; PROTEINS; SERPINS; SIGNAL TRANSDUCTION;

EID: 26644448101     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.2.4.472     Document Type: Note

References (21)

1. Cher M, Biliran HR Jr, Bhagat S, Meng Y, Che M, Lockett J, et al. Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis,. Proc Natl Acad Sci USA 2003; 100:7847-52. (Pubitemid 36760058)
2. Seftor R, Seftor EA, Sheng S, Pemberton PA, Sager R, Hendrix MJC. Maspin Suppresses the Invasive Phenotype of Human Breast Carcinoma. Cancer Res 1998; 58:5681-5. (Pubitemid 29006405)
3. Sheng S, Carey J, Seftor EA, Dias L, Hendrix MJ, Sager R. Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc Natl Acad Sci USA 1996; 93:11669-74. (Pubitemid 26347180)
4. Zhang M, Volpert O, Shi YH, Bouck N. Maspin is an angiogenesis inhibitor. Nat Med 2000; 6:196-9. (Pubitemid 30082365)
5. Zou Z, Anisowicz A, Hendrix MJC, Thor A, Neveu M, Sheng S, et al. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 1994; 263:526-9. (Pubitemid 24082753)
6. Brahmbhatt A, Klemke RL. ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxis. J Biol Chem 2003; 278:13016-25. (Pubitemid 36800069)
7. Chen J, Zhuang S, Nguyen TH, Boss GR, Pilz RB. Oncogenic Ras leads to Rho activation by activating the mitogen-activated protein kinase pathway and decreasing Rho-GTPase-activating protein activity. J Biol Chem 2003; 278:2807-18. (Pubitemid 36801183)
8. Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature 2002; 420:629-35. (Pubitemid 36764489)
9. DeMali K, Barlow CA, Burridge K. Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion. J Cell Biol 2002; 159:881-91. (Pubitemid 36008369)
10. Wittmann T, Bokoch GM, Waterman-Storer CM. Regulation of leading edge microtubule and actin dynamics downstream of Rac1. J Cell Biol 2003; 161:845-51. (Pubitemid 36718418)
11. Sanders L, Matsumura F, Bokoch GM, de Lanerolle P. Inhibition of myosin light chain kinase by p21-activated kinase. Science 1999; 283:2083-5.
12. Goeckeler Z, Masaracchia RA, Zeng Q, Chew TL, Gallagher P, Wysolmerski RB. Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2. J Biol Chem 2000; 275:18366-74. (Pubitemid 30414793)
13. Symons M. Adhesion signaling: PAK meets Rac on solid ground. Curr Biol 2000; 10: R535-7.
14. Cantley L. The phosphoinositide 3-kinase pathway. Science 2002; 296:1655-7. (Pubitemid 34579158)
15. Manser E. Small GTPases take the stage. Dev Cell 2002; 3:323-8.
16. Alahari S, Reddig PJ, Juliano RL. Biological aspects of signal transduction by cell adhesion receptors. Int Rev Cytol 2002; 220:145-84. (Pubitemid 34988797)
17. Parsons J, Martin KH, Slack JK, Taylor JM, Weed SA. Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement. Oncogene 2000; 19:5606-13.
18. Sundberg L, Galante LM, Bill HM, Mack CP, Taylor JM. An endogenous inhibitor of focal adhesion kinase blocks Rac1/JNK- but not Ras/ERK-dependent signaling in vascular smooth muscle cells. J Biol Chem 2003; [Epub ahead of print].
19. Biliran HJ, Sheng S. Pleiotrophic Inhibition of Pericellular Urokinase-type plasminogen activator system by endogenous tumor suppressive maspin. Cancer Res 2001; 61:8676-82. (Pubitemid 34013876)
20. Aguirre Ghiso J. Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo. Oncogene 2002; 21:2513-24. (Pubitemid 34438104)
21. Tarui T, Andronicos N, Czerkay RP, Mazar AP, Bdeir K, Parry GC, et al. Critical role of integrin alpha 5beta 1 in urokinase (uPA) /urokinase receptor (uPAR, CD87) signaling. J Biol Chem 2003; [Epub ahead of print].