The anticarcinogenic effect of propolis in human lymphocytes culture

Phytomedicine

Volumn 12, Issue 10, 2005, Pages 742-747

  Ozkul, Y ^a   Silici, S ^b   Eroglu E ^b  

^a ERCIYES UNIVERSITY MEDICAL FACULTY   (Turkey)

^b ERCIYES UNIVERSITY   (Turkey)

Author keywords

Micronucleus; Mitotic index; Propolis

Indexed keywords

PROPOLIS;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD SAMPLING; CHEMICAL ANALYSIS; CONTROLLED STUDY; EVALUATION; GAS CHROMATOGRAPHY; HUMAN; HUMAN CELL; LYMPHOCYTE; MASS SPECTROMETRY; MICRONUCLEUS; MITOSIS; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

ADULT; ANALYSIS OF VARIANCE; ANTICARCINOGENIC AGENTS; CARCINOGENS; CELLS, CULTURED; HUMANS; LYMPHOCYTES; MALE; MICRONUCLEUS TESTS; MITOTIC INDEX; PROPOLIS;

EID: 26444610035     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2004.06.015     Document Type: Article

References (43)

1. M. Amoros, C.M.O. Simoes, L. Girre, F. Sauvager, and M. Cormier Comparision of the anti-Herpes simplex virus activities of propolis and 3-methyl-butyl-2-enyl caffeate J. Nat. Products 57 1994 644 647
2. V. Bankova, and M.C. Marcucci Standardization of propolis: present status and perspectives Bee World 81 14 2000 182 188
3. V. Bankova, S. Popov, and N. Marekov On the chemical composition of some propolis fraction with antiviral action Acta Microbiol. Bulg. 23 1988 52 57
4. A.H. Banskota, Y. Tezuka, K. Midorikawa, K. Matsushige, and S. Kadota Two nowel cytotoxic benzofuran derivatives from Brazilian propolis J. Nat. Products 63 9 2000 1277 1279
5. S.E. Benner, M.J. Wargovich, S.M. Lippman, R. Fisher, M. Velasco, R.J. Winn, and W.K. Hong Reduction in oral mucosa micronuclei frequency following alpha-tocopherol treatment of oral leukoplakia Cancer Epidomiol. Biomarkers Prev. 3 1994 73 76
6. M.B. Carvalho Historia natural do cancer da cavidade oral A. Rapopart Cancer da Boca 1997 Pancast Sao Paulo, SP, Brazil 17 29
7. S.S. Desai, S.D. Ghaisas, S.D. Jakhi, and S.V. Bhide Cytogenetic damage in exfoliated oral muosa cells and circulating lymphocytes of patients suffering from precancerous oral lesions Cancer Lett. 109 1996 9 14
8. E.E. Deschner, J. Ruperto, G. Wonk, and H.L. Newmark Quercetin and rutin as inhibitors of azoxymethanol induced colonic neoplasia Carcinogenesis 12 1991 771 775
9. V. Dimov, N. Ivanovska, N. Manolova, V. Bankova, N. Nikolov, and S. Popov Immunomodulatory action of propolis. Influence on anti-infectious protection and macrophage function Apidologie 22 1991 155 162
10. H.J. Evans Historical perspectives on the development of the in vitro micronucleus test: a personal view. Mutat. Res. 392 1997 5 10
11. K. Frenkel, H. Wei, R. Bhimani, J. Ye, J.A. Zadunaisky, M.T. Huang, T. Ferraro, A.H. Conney, and D. Grunberger Inhibition of tumor promoter-mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester Cancer Res. 53 1993 1255 1261
12. E.L. Ghisalberti Propolis: a review Bee World 60 1979 59 84
13. J.A. Heddle, M. Hite, B. Kirkhart, K. Mavournin, J.T. MacGregor, G.W. Newell, and M.F. Salamone The induction of micronuclei as a measure of genotoxicity. A report of the US Environmental Protection Agency Gene Tox Program. Mutat. Res. 123 1983 61 118
14. M. Kartal, S. Yildiz, S. Kaya, S. Kurucu, and G. Topçu Antimicrobial activity of propolis samples from different regions of Anatolia J. Ethnopharmacol. 2860 2003 1 5
15. N. Keskin, S. Hazir, K.H.C. Baser, and M. Kürkçü oǧlu Antibacterial activity and chemical composition of Turkish propolis Z. Naturforsch. 56c 2001 1112 1115
16. A. Kujumgiev, I. Tsvetkova, Yu. Serkedjieva, V. Bankova, R. Christov, and S. Popov Antibacterial, antifungal and antiviral activity of propolis of different geographic origin J. Ethnopharmacol. 64 1999 235 240
17. V. Kumar, N.N. Rao, and N.S. Nair Micronuclei in oral squamous cell carcinoma. A marker of genotoxic damage Indian J. Dent. Res. 11 2000 101 106
18. W. Liu Improvement of micronucleus test method in peripheral blood lymphocytes and preliminary observations in clinical use Chin. J. Med. Testing 15 4 1992 233 234
19. M. Manolovan, V. Maximova, G. Gegova, Yu Serkedjieva, S. Uzunov, N. Marekov, and V. Bankova On the influenza action of fractions from propolis C R Acad. Bulg. Sci. 38 1985 735 738
20. T. Matsuno, Y. Matsumoto, M. Saito, and J. Morikawa Isolation and characterization of cytotoxic diterpenoid isomers from Propolis Z. Naturforsch. 52c 1997 702 704
21. H. Miyataka, M. Nishiki, H. Matsumoto, T. Fujimoto, M. Matsuka, and T. Satoh Evaluation of propolis. I. Evaluation of Brazilian and Chinese propolis by enzymatic and phsico-chemical methods Biol. Pharm. Bull. 20 1997 496 501
22. Nikolov, N., Marekov, N., Bankova, V., Popov, S., Ignatova, R., Vladimirova, I., 1987. Method for the preparation of water-soluble derivative of propolis. Bulgarian patent Application N 79903/28.05.1987.
23. G. Obe, and A.T. Natarajan Chromosomal Aberrations 1990 Springer Berlin, Germany
24. H. Orhan, S. Marol, İ.F. Hepsen, and G. Şahin Effects of some probable antiooxidants on selenite-induced cataract formation and oxidative stress-related parameters in rats Toxicology 139 3 1999 219 232
25. C. Ota, C. Unterkircher, V. Fantinato, and M.T. Shimuzu Antifungal activity of propolis on different species of Candida Mycoses 44 2001 375 378
26. M. Paintz, and J. Metzner Zur lokalanasthetischen Wirkung von Propolis und einigen Inhaltsstoffen Pharmazie 34 1979 839 841
27. M. Popova, S. Silici, O. Kaftanoglu, and V. Bankova Antibacterial activity of Turkish propolis and its qualitative and quantitative chemical composition Phytomedicine 12 3 2004 221 228
28. A. Ramalho, I. Sunjevaric, and A.T. Natarajan Use of the frequencies of micronuclei as quantitative indicators of X-ray-induced chromosomal aberrations in human peripheral blood lymphocytes: comparison of two methods Mutat. Res. 207 3-4 1988 141 146
29. A. Ramirez, G.J.F. Gattás, M.B. Carvalho, A. Rapopport, and P.H. Saldanha Clinical implications of micronuclei frequency as a biomonitor for alcoholic patients with oral carcinomas A.K. Varma Oral Oncol. Vol. VI 1999 MacMillan New York, NY, USA 199 204
30. C.V. Rao, D. Desai, B. Kaul, S. Amin, and B.S. Reddy Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth Chemico-Biol. Interactions 84 1992 277 290
31. C.V. Rao, D. Desai, B. Simi, N. Kulkarni, S. Amin, and B.S. Reddy Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon Cancer Res. 53 1993 4182 4188
32. D.M. Roberts Comparative cytology of the oral cavities of snuff users Acta Cytol. 41 1997 1008 1014
33. N.L. Rudd, S.E. Williams, M. Evans, U.G. Hennig, and D.I. Hoar Kinetochore analysis of micronuclei allows insights into the actions of colcemid and mitomycin C Mutat. Res. 261 1 1991 57 68
34. A.C.H.F. Sawaya, A.M. Palma, F.M. Caetano, M.C. Marcucci, I.B. Silvacunha, C.E.P. Araujo, and M.T. Shimizu Comparative study of in vitro methods used to analyse the activity of propolis extracts with different compositions against species of Candida Lett. Appl. Microbiol. 35 2002 203 207
35. R. Scarpato, and L. Migliore Comparison of spontaneous structural chromosome aberration frequency in 48 h-cultured human lymphocytes mitotically arrested by different colchemid treatments Mutat. Res. 361 1996 35 39
36. S. Scheller, W. Krol, J. Swiacik, S. Owczarek, S. Gabrys, and J. Shani Antitumoral property of ethanolic extract of propolis in mice-bearing Ehrlich carcinoma, as compared to bleomycin Z. Naturforsch. 44c 1989 1063 1065
37. H.K. Seitz, G. Poschl, and U.A. Simannowski Alcohol and cancer Recent Dev. Alcohol. 14 1998 67 95
38. J.M. Sforcin, A. Fernandes Jr, C.A.M. Lopes, V. Bankova, and S.R.C. Funari Seasonal effect on Brazilian propolis antibacterial activity J. Ethnopharmacol. 73 2000 243 249
39. K. Sorkun, B. Süer, and B. Salih Determination of chemical composition of Turkish propolis Z. Naturforsch. 56c 2001 666 668
40. H.F. Stich, J.R. Curtis, and B.B. Parida Application of the micronucleus test to exfoliated cells of high cancer risk groups: tobacco chewers Int. J. Cancer 30 1982 553 559
41. G.F. Sud'ina, O.K. Mirzoeva, and M.A. Pushkareva Caffeic acid phenetyl ester as a lypoxigenase inhibitor with antioxidant properties FEBS Lett. 329 1993 21 24
42. M. Velikova, V. Bankova, K. Sorkun, S. Popov, and E. Kujumgiev Chemical biological activity of propolis from Turkish and Bulgarian origin Mellifera 1 2001 57 59
43. A.K. Verma, J.A. Johnson, M.N. Gould, and M.A. Tanner Inhibition of 7,12-dimethylbenz [a] anthracene and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin Cancer Res. 48 1988 5754 5758