Tobacco smoking, estrogen receptor α gene variation and small low density lipoprotein level

Human Molecular Genetics

Volumn 14, Issue 16, 2005, Pages 2405-2413

  Shearman, Amanda M ^a   Demissie, Serkalem ^b   Cupples, L Adrienne ^b   Peter, Inga ^c   Schmid, Christopher H ^c   Ordovas, Jose M ^d   Mendelsohn, Michael E ^e   Housman, David E ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BOSTON UNIVERSITY   (United States)

^c TUFTS MEDICAL CENTER   (United States)

^d TUFTS UNIVERSITY   (United States)

^e TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR ALPHA; GENOMIC DNA; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; ALLELE; ARTICLE; ATHEROGENESIS; CARDIOVASCULAR RISK; EXON; FEMALE; GENDER; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PARTICLE SIZE; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; RECEPTOR GENE; RISK FACTOR; SMOKING; TOBACCO;

ESTROGEN RECEPTOR ALPHA; FEMALE; GENOTYPE; HUMANS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; RISK FACTORS; SMOKING; VARIATION (GENETICS);

NICOTIANA TABACUM;

EID: 26444454586     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi242     Document Type: Article

References (51)

1. Mendelsohn, M.E. and Karas, R.H. (1999) The protective effects of estrogen on the cardiovascular system. [i#N. Engl. J. Med.#1i], [b#340#1b] 1801-1811.
2. Jensen, J., Christiansen, C. and Rodbro, P. (1985) Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause. [i#N. Engl. J. Med.#1i], [b#313#1b], 973-975.
3. Michnovicz, J.J., Hershcopf, R.J., Naganuma, H., Bradlow, H.L. and Fishman, J. (1986) Increased 2-hydroxylation of estradiol as a possible mechanism for the anti-estrogenic effect of cigarette smoking. [i#N. Engl. J. Med.#1i], [b#315#1b], 1305-1309.
4. Johnson, M.D., Kenney, N., Stoica, A., Hilakivi-Clarke, L., Singh, B., Chepko, G., Clarke, R., Sholler, P.F., Lirio, A.A., Foss, C. [i#et al.#1i] (2003) Cadmium mimics the [i#in vivo#1i] effects of estrogen in the uterus and mammary gland. [i#Nat. Med.#1i], [b#9#1b], 1081-1084.
5. Meek, M.D. and Finch, G.L. (1999) Diluted mainstream cigarette smoke condensates activate estrogen receptor and aryl hydrocarbon receptor-mediated gene transcription. [i#Environ. Res.#1i], [b#80#1b], 9-17.
6. Demissie, S., Cupples, L.A., Shearman, A.M., Gruenthal, K.M., Peter, I., Schmid, C.H., Karas, R.H., Housman, D.E., Mendelsohn, M.E., Ordovas, J.M. (2005) Estrogen receptor-alpha variants are associated with lipoprotein size distribution and particle levels in women: The Framingham Heart Study. [i#Atherosclerosis#1i]. Jul 6; [Epub ahead of print].
7. Berneis, K.K. and Krauss, R.M. (2002) Metabolic origins and clinical significance of LDL heterogeneity. [i#J. Lipid Res.#1i], [b#43#1b], 1363-1379.
8. Rotter, J.I., Bu, X., Cantor, R.M., Warden, C.H., Brown, J., Gray, R.J., Blanche, P.J., Krauss, R.M. and Lusis, A.J. (1996) Multilocus genetic determinants of LDL particle size in coronary artery disease families. [i#Am. J. Hum. Genet.#1i], [b#58#1b], 585-594.
9. Austin, M.A., Edwards, K.L., Monks, S.A., Koprowicz, K.M., Brunzell, J.D., Motulsky, A.G., Mahaney, M.C. and Hixson, J.E. (2003) Genome-wide scan for quantitative trait loci influencing LDL size and plasma triglyceride in familial hypertriglyceridemia. [i#J. Lipid Res.#1i], [b#44#1b], 2161-2168.
10. Bosse, Y., Perusse, L. and Vohl, M.C. (2004) Genetics of LDL particle heterogeneity: From genetic epidemiology to DNA-based variations. [i#J. Lipid Res.#1i], [b#45#1b], 1008-1026.
11. Lehtimaki, T., Kunnas, T.A., Mattila, K.M., Perola, M., Penttila, A., Koivula, T. and Karhunen, P.J. (2002) Coronary artery wall atherosclerosis in relation to the estrogen receptor 1 gene polymorphism: An autopsy study. [i#J. Mol. Med.#1i], [b#80#1b], 176-180.
12. Shearman, A.M., Cupples, L.A., Demissie, S., Peter, I., Schmid, C.H., Karas, R.H., Mendelsohn, M.E., Housman, D.E. and Levy, D. (2003) Association between estrogen receptor alpha gene variation and cardiovascular disease. [i#JAMA#1i], [b#290#1b], 2263-2270.
13. Herrington, D.M., Howard, T.D., Hawkins, G.A., Reboussin, D.M., Xu, J., Zheng, S.L., Brosnihan, K.B., Meyers, D.A. and Bleecker, E.R. (2002) Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. [i#N. Engl. J. Med.#1i], [b#346#1b], 967-974.
14. Koivu, T.A., Fan, Y.M., Mattila, K.M., Dastidar, P., Jokela, H., Nikkari, S.T., Kunnas, T., Punnonen, R. and Lehtimaki, T. (2003) The effect of hormone replacement therapy on atherosclerotic severity in relation to ESR1 genotype in postmenopausal women. [i#Maturitas#1i], [b#44#1b], 29-38.
15. Khosla, S., Riggs, B.L., Atkinson, E.J., Oberg, A.L., Mavilia, C., Del Monte, F., Melton, L.J., III and Brandi, M.L. (2004) Relationship of estrogen receptor genotypes to bone mineral density and to rates of bone loss in men. [i#J. Clin. Endocrinol. Metab.#1i], [b#89#1b], 1808-1816.
16. Jeng, M.H., Shupnik, M.A., Bender, T.P., Westin, E.H., Bandyopadhyay, D., Kumar, R., Masamura, S. and Santen, R.J. (1998) Estrogen receptor expression and function in long-term estrogen-deprived human breast cancer cells. [i#Endocrinology#1i], [b#139#1b], 4164-4174.
17. Herrington, D.M., Howard, T.D., Brosnihan, K.B., McDonnell, D.P., Li, X., Hawkins, G.A., Reboussin, D.M., Xu, J., Zheng, S.L., Meyers, D.A. [i#et al.#1i] (2002) Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein. [i#Circulation#1i], [b#105#1b], 1879-1882.
18. Ordovas, J.M. and Shen, A.H. (2002) Genetics, the environment, and lipid abnormalities. [i#Curr. Cardiol. Rep.#1i], [b#4#1b], 508-513.
19. Wang, X., Zuckerman, B., Pearson, C., Kaufman, G., Chen, C., Wang, G., Niu, T., Wise, P.H., Bauchner, H. and Xu, X. (2002) Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight. [i#JAMA#1i] [b#287#1b], 195-202.
20. Wilson, P.W., Garrison, R.J. and Castelli, W.P. (1985) Postmenopausal estrogen use, cigarette smoking, and cardiovascular morbidity in women over 50. The Framingham Study. [i#N. Engl. J. Med.#1i], [b#313#1b], 1038-1043.
21. Schuit, S.C., Oei, H.H., Witteman, J.C., Geurts van Kessel, C.H., van Meurs, J.B., Nijhuis, R.L., van Leeuwen, J.P., de Jong, F.H., Zillikens, M.C., Hofman, A. [i#et al.#1i] (2004) Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction. [i#JAMA#1i], [b#291#1b], 2969-2977.
22. Ogawa, S., Lubahn, D.B., Korach, K.S. and Pfaff, D.W. (1997) Behavioral effects of estrogen receptor gene disruption in male mice. [i#Proc. Natl Acad. Sci. USA#1i], [b#94#1b], 1476-1481.
23. Ogawa, S., Inoue, S., Watanabe, T., Orimo, A., Hosoi, T., Ouchi, Y. and Muramatsu, M. (1998) Molecular cloning and characterization of human estrogen receptor betacx: A potential inhibitor of estrogen action in human. [i#Nucleic Acids Res.#1i], [b#26#1b], 3505-3512.
24. Bosse, Y., Perusse, L., Despres, J.P., Lamarche, B., Chagnon, Y.C., Rice, T., Rao, D.C., Bouchard, C. and Vohl, M.C. (2003) Evidence for a major quantitative trait locus on chromosome 17q21 affecting low-density lipoprotein peak particle diameter. [i#Circulation#1i], [b#107#1b], 2361-2368.
25. Barzilai, N., Atzmon, G., Schechter, C., Schaefer, E.J., Cupples, A.L., Lipton, R., Cheng, S. and Shuldiner, A.R. (2003) Unique lipoprotein phenotype and genotype associated with exceptional longevity. [i#JAMA#1i] [b#290#1b], 2030-2040.
26. Wilson, P.W., Garrison, R.J., Abbott, R.D. and Castelli, W.P. (1983) Factors associated with lipoprotein cholesterol levels. The Framingham study. [i#Arteriosclerosis#1i], [b#3#1b], 273-281.
27. Comings, D.E., Muhleman, D., Johnson, P. and MacMurray, J.P. (1999) Potential role of the estrogen receptor gene (ESR1) in anxiety. [i#Mol. Psychiatry#1i], [b#4#1b], 374-377.
28. Prichard, Z., Jorm, A.F., Prior, M., Sanson, A., Smart, D., Zhang, Y., Hattley, G. and Easteal, S. (2002) Association of polymorphisms of the estrogen receptor gene with anxiety-related traits in children and adolescents: A longitudinal study. [i#Am. J. Med. Genet.#1i], [b#114#1b], 169-176.
29. Westberg, L., Melke, J., Landen, M., Nilsson, S., Baghaei, F., Rosmond, R., Jansson, M., Holm, G., Bjorntorp, P. and Eriksson, E. (2003) Association between a dinucleotide repeat polymorphism of the estrogen receptor alpha gene and personality traits in women. [i#Mol. Psychiatry#1i] [b#8#1b], 118-122.
30. Smith, T.W., Houston, B.K. and Zurawski, R.M. (1983) The Framingham type A Scale and anxiety, irrational beliefs, and self-control. [i#J. Human Stress#1i], [b#9#1b], 32-37.
31. Markovitz, J.H., Matthews, K.A., Kannel, W.B., Cobb, J.L. and D'Agostino, R.B. (1993) Psychological predictors of hypertension in the Framingham Study. Is there tension in hypertension? [i#JAMA#1i], [b#270#1b] 2439-2443.
32. Schumann, A., Hapke, U., Rumpf, H.J., Meyer, C. and John, U. (2001) The association between degree of nicotine dependence and other health behaviours. Findings from a German general population study. [i#Eur. J. Public Health#1i], [b#11#1b], 450-452.
33. Jick, H. and Porter, J. (1977) Relation between smoking and age of natural menopause. Report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center. [i#Lancet#1i], [b#1#1b], 1354-1355.
34. Lohmueller, K.E., Pearce, C.L., Pike, M., Lander, E.S. and Hirschhorn, J.N. (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. [i#Nat. Genet.#1i], [b#33#1b], 177-182.
35. Cardon, L.R. and Palmer, L.J. (2003) Population stratification and spurious allelic association. [i#Lancet#1i], [b#361#1b], 598-604.
36. Botstein, D. and Risch, N. (2003) Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex disease. [i#Nat. Genet.#1i], [b#33#1b](suppl), 228-237.
37. Smith, E.P., Boyd, J., Frank, G.R., Takahashi, H., Cohen, R.M., Specker, B., Williams, T.C., Lubahn, D.B. and Korach, K.S. (1994) Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. [i#N. Engl. J. Med.#1i], [b#331#1b], 1056-1061.
38. Sudhir, K., Chou, T., Chatterjee, K., Smith, E., Williams, T., Kane, J., Malloy, M., Korach, K. and Rubanyi, G. (1997) Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. [i#Circulation#1i], [b#96#1b], 3774-3777.
39. Bruning, J.C., Lingohr, P., Gillette, J., Hanstein, B., Avci, H., Krone, W., Muller-Wieland, D. and Kotzka, J. (2003) Estrogen receptor-alpha and Sp1 interact in the induction of the low density lipoprotein-receptor. [i#J. Steroid Biochem. Mol. Biol.#1i], [b#86#1b], 113-121.
40. Allayee, H., Dominguez, K.M., Aouizerat, B.E., Krauss, R.M., Rotter, J.I., Lu, J., Cantor, R.M., de Bruin, T.W. and Lusis, A.J. (2000) Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia. [i#J. Lipid Res.#1i], [b#41#1b], 245-252.
41. Jones, D.R., Schmidt, R.J., Pickard, R.T., Foxworthy, P.S. and Eacho, P.I. (2002) Estrogen receptor-mediated repression of human hepatic lipase gene transcription. [i#J. Lipid Res.#1i], [b#43#1b], 383-391.
42. Homma, H., Karachi, H., Nishio, Y., Takeda, T., Yamamoto, T., Adachi, K., Morishige, K., Ohmichi, M., Matsuzawa, Y. and Murata, Y. (2000) Estrogen suppresses transcription of lipoprotein lipase gene. Existence of a unique estrogen response element on the lipoprotein lipase promoter. [i#J. Biol. Chem.#1i], [b#275#1b], 11404-11411.
43. Lambert, J.C., Coyle, N. and Lendon, C. (2004) The allelic modulation of apolipoprotein E expression by oestrogen: Potential relevance for Alzheimer's disease. [i#J. Med. Genet.#1i], [b#41#1b], 104-112.
44. Ordovas, J.M., Cripples, L.A., Corella, D., Otvos, J.D., Osgood, D., Martinez, A., Lahoz, C., Coltell, O., Wilson, P.W. and Schaefer, E.J. (2000) Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: The Framingham study. [i#Arterioscler. Thromb. Vasc. Biol.#1i], [b#20#1b], 1323-1329.
45. Blake, G.J., Otvos, J.D., Rifai, N. and Ridker, P.M. (2002) Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women. [i#Circulation#1i], [b#106#1b], 1930-1937.
46. Grundy, S.M., Vega, G.L., Otvos, J.D., Rainwater, D.L. and Cohen, J.C. (1999) Hepatic lipase activity influences high density lipoprotein subclass distribution in normotriglyceridemic men. Genetic and pharmacological evidence. [i#J. Lipid Res.#1i], [b#40#1b], 229-234.
47. Otvos, J.D. (2002) Measurement of lipoprotein subclass profiles by nuclear magnetic resonance spectroscopy. [i#Clin. Lab.#1i], [b#48#1b], 171-180.
48. Felson, D.T., Kiel, D.P., Anderson, J.J. and Kannel, W.B. (1988) Alcohol consumption and hip fractures: The Framingham Study. [i#Am. J. Epidemiol.#1i], [b#128#1b], 1102-1110.
49. Kannel, W.B. and Sorlie, P. (1979) Some health benefits of physical activity. The Framingham Study. [i#Arch. Intern. Med.#1i], [b#139#1b], 857-861.
50. van Meurs, J.B., Schuit, S.C., Weel, A.E., van der Klift, M., Bergink, A.P., Arp, P.P., Colin, E.M., Fang, Y., Hofman, A., van Duijn, C.M. [i#et al.#1i] (2003) Association of 5′ estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk. [i#Hum. Mol. Genet.#1i], [b#12#1b], 1745-1754.
51. Schuit, S.C., van Meurs, J.B., Bergink, A.P., van der Klift, M., Fang, Y., Leusink, G., Hofman, A., van Leeuwen, J.P., Uitterlinden, A.G. and Pols, H.A. (2004) Height in pre- and postmenopausal women is influenced by estrogen receptor alpha gene polymorphisms. [i#J. Clin. Endocrinol. Metab.#1i], [b#89#1b], 303-309.