Immunolocalization of the apoptosis regulating proteins Bcl-2 and Bax in human endometrium and isolated peritoneal fluid macrophages in endometriosis

Human Reproduction

Volumn 12, Issue 1, 1997, Pages 146-152

  McLaren, J ^a,b   Prentice, A ^a   Charnock Jones, D S ^a   Sharkey, A M ^a   Smith, S K ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Apoptosis; Bax; Bcl 2; Endometriosis; Peritoneal fluid macrophages

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2;

ADULT; APOPTOSIS; ARTICLE; CELL SUBPOPULATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIOSIS; ENDOMETRIUM; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PERITONEAL FLUID; PERITONEUM MACROPHAGE; TISSUE DISTRIBUTION;

EID: 0031039563     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/12.1.146     Document Type: Article

References (44)

1. Adams, D.O. and Hamilton, T.A. (1992) Molecular basis of macrophage activation diversity and its origin. In Lewis, C.E. and McGee, J.-O. (eds), The Macrophage. IRL Press, Oxford, pp. 77-114.
2. Albina, J.E., Cui, S., Mateo, R.B. and Reichner, J.S. (1993) Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J. Immunol., 150, 5080-5085.
3. American Fertility Society (1985) Revised American Fertility Society classification of endometriosis Fertil. Steril., 43, 351-352.
4. Boise, L.H., Gonzalez-Garcia, M., Postema, C.E. et al. (1993) Bcl-x, a Bcl-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell., 74, 597-608.
5. Cerami, A. (1992) Inflammatory cytokines. Clin. Immunol. Immunopathol., 62, S3-S10.
6. Eischen, A., Duclos, B., Schmitt-Gognel, M. et al. (1994) Human resident peritoneal macrophages: phenotype and histology. Br. J. Haematol., 88, 712-722.
7. Gompel, A., Sabourin, J.C., Martin, A. et al. (1994) Bcl-2 expression in normal endometrium during the menstrual cycle. Am. J. Pathol., 144, 1195-1202.
8. Halme, J. (1989) Release of TNF-α by human peritoneal macrophages in vivo and in vitro. Am. J. Obstet. Gynecol., 161, 1718-1725.
9. Halme, J., Becker, S. and Haskill, S. (1987) Altered maturation and function of peritoneal macrophages: possible role in pathogenesis of endometriosis. Am. J. Obstet. Gynecol. 156, 783-789.
10. Halme, J., Becker, S., Hammond, M.G. et al. (1983) Increased activation of pelvic macrophages in infertile women with mild endometriosis. Am. J. Obstet. Gynecol., 145, 333-337.
11. Harada, M., Suganuma, N., Furuhashi, M. et al. (1996) Detection of apoptosis in human endometriotic tissues. Mol. Hum. Reprod., 2, 307-315.
12. Hopwood, D. and Levison, D.A. (1976) Atrophy and apoptosis in cyclical human endometrium. J. Pathol., 119, 159-165.
13. Jenkins, S., Olive, D.L. and Haney, A.F. (1986) Endometriosis: pathogenetic implications of the anatomic distribution. Obstet. Gynecol., 67, 335-338.
14. Keenan, J.A., Chen, T.T., Chadnell, N.L. et al. (1994) Interferon-γ and interleukin-6 in peritoneal fluid and macrophage conditioned media of women with endometriosis. Am. J. Reprod. Immunol., 32, 180-183.
15. Keifer, M.C., Brauer, M.J., Powers, V.C. et al. (1995) Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature, 374, 736-739.
16. Kerr, J.F.R., Winterford, C.M. and Harmon, B.V. (1993) Apoptosis. Its significance in cancer and cancer therapy. Cancer, 73, 2013-2026.
17. Koh, E.A.T., Illingworth, P.J., Duncan, W.C. and Critchley, H.O.D. (1995) Immunolocalization of Bcl-2 protein in human endometrium in the menstrual cycle and simulated early pregnancy. Hum. Reprod., 10, 1557-1562.
18. McLaren, J., Prentice, A., Charnock-Jones, D.S. et al. (1996) Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steriods J. Clin. Invest., 98, 482-489.
19. Munn, D.H., Beall, A.C., Song, D. et al. (1995) Activation-induced apoptosis in human macrophages. Developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon-γ. J. Exp. Med., 181, 127-136.
20. Nagata, S. and Golstein, P. (1995) The Fas death factor. Science, 267, 1449-1455.
21. Nathan, C.F., Murray, H.W. and Cohn, Z.A. (1980) Current concepts. The macrophage as an effector cell. N. Engl. J. Med., 303, 622-626.
22. Nawaz, S., Lynch, M.P., Galand, P. and Gerschenson, L.E. (1987) Hormonal regulation of cell death in rabbit uterine epithelium. Am. J. Pathol., 127, 51-59.
23. Nunez, G. and Clarke, M.F. (1994) The Bcl-2 family of proteins: regulators of cell death and survival. Trends Cell Biol., 4, 399-403.
24. Oltvai, Z.N., Milliman, C.L. and Korsmeyer, S.T. (1993) Bcl-2 heterodimerises in vivo with a conserved homologue Bax that accelerates programmed cell death. Cell, 74, 609-619.
25. Oltvai, Z.N. and Korsmeyer, S.J. (1994) Checkpoints of dueling dimers foil death wishes. Cell, 79, 189-192.
26. Osborne, B.A. and Schwartz, L.M. (1994) Essential genes that regulate apoptosis. Trends Cell Biol., 4, 394-398.
27. Otsuki, Y., Misaki, O., Sugimoto, O., Ito, Y. et al. (1994) Cyclic Bcl-2 gene expression in human endometrium during human menstrual cycle. Lancet, 344, 28-29.
28. Polan, M.L., Loukides, J., Nelson, P. et al. (1989) Progesterone and estrogen modulate interleukin-1β mRNA levels in cultured human peripheral monocytes. J. Clin. Endocrinol. Metab., 69, 1200-1206.
29. Ramsey, J.W. (1993) Peritoneal fluid: its relevance to the development of endometriosis. Fertil. Steril., 60, 1-14.
30. Reid, V.C., Mitchinson, M.J. and Skepper, J.N. (1993) Cytotoxicity of oxidised low density lipoproteins to mouse peritoneal macrophages: An ultrastructural study. J. Pathol., 171, 321-328.
31. Rier, S.E., Parsons, A.K. and Becker, J.L. (1994) Altered interleukin-6 production by peritoneal leukocytes from patients with endometriosis. Fertil. Steril., 61, 294-299.
32. Rotello, R.J., Hocker, M.B. and Gerschenson, L.E. (1989) Biochemical evidence for programmed cell death in rabbit uterine epithelium. Am. J. Pathol., 134, 491-495.
33. Simoni, J., Simoni, G., Lox, C.D. et al. (1994) Cytokines and PAF release from human monocytes and macrophages. Effects of hemoglobin and contaminants. Art. Cells. Blood Subs. Immobilis.Biotechnol., 22, 523-534.
34. Strathy, J.H., Molgaard, C.A. and Coulman, C.B. (1982) Endometriosis and infertility: a laparoscopic study of endometriosis among fertile and infertile women. Fertil. Steril., 38, 667-672.
35. Sunderkotter, C., Goebeler, M., Schulze-Osthoff, K. et al. (1991) Macrophage-derived angiogenesis factors. Pharmacol Ther., 51, 195-216.
36. Tabibzadeh, S., Kong, Q.F., Satyaswaroop, P.G. et al. (1994) Distinct regional and menstrual cycle dependent distribution of apoptosis in human endometrium. Potential regulatory role of T-cells and TNF-α. Endocrinol. J., 2, 87-95.
37. Tabibzadeh, S., Zupi, E., Babaknia, A. et al. (1995) Site and menstrual cycle-dependent expression of proteins of the tumour necrosis factor (TNF) receptor family and Bcl-2 oncoprotein and phase specific production of TNF-α in human endometrium. Hum. Reprod., 10, 277-286.
38. Teixeira, C., Reed, J.C. and Pratt, M.A.C (1995) Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells. Cancer Res., 55, 3902-3907.
39. Thomas, E.J. and Prentice, A. (1992) The aetiology and pathogenesis of endometriosis. Reprod. Med. Rev., 1, 21-36.
40. Vinatier, D., Dufour, Ph. and Subtil, D. (1996) Apoptosis: a programmed cell death involved in ovarian and uterine physiology. Eur. J. Obstet. Gynaecol. Reprod. Biol., 67, 85-102.
41. White, E. (1993) Death-defying acts: a meeting review on apoptosis. Genes Dev., 7, 2277-2284.
42. Williams, G.T. (1994) Apoptosis in the immune system. J. Pathol., 173, 1-4.
43. Williams, G.T., Smith, C.A., McCarthy, N.J. and Grimes, E.A. (1992) Apoptosis: final control point in cell biology. Trends Cell Biol., 2, 263-267.
44. Yang, E., Zha, J., Jockel, J. et al. (1995) Bad, a heterodimeric partner for Bcl-xl and Bcl-2. Displaces Bax and promotes cell death. Cell, 80, 285-291.