A specific synaptic pathway activates a conditional plateau potential underlying protraction phase in the Aplysia feeding central pattern generator

Journal of Neuroscience

Volumn 24, Issue 22, 2004, Pages 5230-5238

  Dembrow, Nikolai C ^a   Jing, Jian ^a   Brezina, Vladimir ^a   Weiss, Klaudiusz R ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Aplysia; Conditional plateau potential; Convergence; Feeding circuitry; Muscarinic action; Neuronal networks

Indexed keywords

HEXAMETHONIUM; MEGLUMINE; OXOTREMORINE; PIRENZEPINE; TETRODOTOXIN;

ANIMAL CELL; APLYSIA; ARTICLE; CONTROLLED STUDY; MOTOR ACTIVITY; NERVE CELL NETWORK; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SYNAPSE; VOLTAGE CLAMP;

ANIMALS; APLYSIA; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; FEEDING BEHAVIOR; GANGLIA, INVERTEBRATE; INTERNEURONS; MEMBRANE POTENTIALS; MOTOR NEURONS; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; NERVE NET; NEURAL PATHWAYS; NEURONS; NICOTINIC ANTAGONISTS; PATCH-CLAMP TECHNIQUES; SODIUM CHANNEL BLOCKERS; SYNAPTIC TRANSMISSION;

EID: 2642580953     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5649-03.2004     Document Type: Article

References (30)

1. Abbott L, Sejnowski T (1999) Neural codes and distributed representations, foundations of neural computation. Cambridge, MA: MIT.
2. Amit DJ (1989) Modeling brain function, the wold of attractor neural networks. New York: Cambridge UP.
3. Cattaert D, Araque A, Buno W, Clarac F (1994) Nicotinic and muscarinic activation of motoneurons in the crayfish locomotor network. J Neurophysiol 72:1622-1633.
4. Dembrow NC, Jing J, Brezina V, Weiss KR (2002) A specific synaptic pathway activates the plateau potential responsible for the maintenance of the protraction phase in the Aplysia feeding central pattern generator. Soc Neurosci Abstr 28:367-13.
5. Dembrow NC, Jing J, Proekt A, Romero A, Vilim FS, Cropper EC, Weiss KR (2003) A newly identified buccal interneuron initiates and modulates feeding motor programs in Aplysia. J Neurophysiol 90:2190-2204.
6. Elson RC, Panchin YV, Arshavsky YI, Selverston AI (1994) Multiple effects of an identified proprioceptor upon gastric pattern generation in spiny lobsters. J Comp Physiol [A] 174:317-329.
7. Fraser DD, MacVicar BA (1996) Cholinergic-dependent plateau potential in hippocampal CA1 pyramidal neurons. J Neurosci 16:4113-4128.
8. Fritschy JM, Johnson DK, Mohler H, Rudolph U (1998) Independent assembly and subcellular targeting of GABA(A)-receptor subtypes demonstrated in mouse hippocampal and olfactory neurons in vivo. Neurosci Lett 249:99-102.
9. Getting P (1989) Emerging principles from central pattern generator networks. Annu Rev Neurosci 12:185-204.
10. Gorczyca MG, Budnik V, White K, Wu CF (1991) Dual muscarinic and nicotinic action on a motor program in Drosophila. J Neurobiol 22:391-404.
11. Hurwitz I, Goldstein RS, Susswein AJ (1994) Compartmentalization of pattern-initiation and motor functions in the B31 and B32 neurons of the buccal ganglia of Aplysia californica. J Neurophysiol 71:1514-1527.
12. Hurwitz I, Neustadter D, Morton DW, Chiel HJ, Susswein AJ (1996) Activity patterns of the B31/B32 pattern initiators innervating the I2 muscle of the buccal mass during normal feeding movements in Aplysia californica. J Neurophysiol 75:1309-1326.
13. Hurwitz I, Kupfermann I, Susswein AJ (1997) Different roles of neurons B63 and B34 that are active during the protraction phase of buccal motor programs in Aplysia californica. J Neurophysiol 78:1305-1319.
14. Hurwitz I, Kupfermann I, Weiss KR (2003) Fast synaptic connections from CBIs to pattern-generating neurons in Aplysia: initiation and modification of motor programs. J Neurophysiol 89:2120-2136.
15. Kawasaki H, Palmieri C, Avoli M (1999) Muscarinic receptor activation induces depolarizing plateau potentials in bursting neurons of the rat subiculum. J Neurophysiol 82:2590-2601.
16. Kiehn O, Johnson BR, Raastad M (1996) Plateau properties in mammalian spinal interneurons during transmitter-induced locomotor activity. Neuroscience 75:263-273.
17. Kristan Jr WB, Shaw BK (1997) Population coding and behavioral choice. Curr Opin Neurobiol 7:826-831.
18. Kupfermann I (1974) Feeding behavior in Aplysia: a simple system for the study of motivation. Behav Biol 10:1-26.
19. Marder E, Calabrese RL (1996) Principles of rhythmic motor pattern generation. Physiol Rev 76:687-717.
20. Morton DW, Chiel HJ (1993) In vivo buccal nerve activity that distinguishes ingestion from rejection can be used to predict behavioral transitions in Aplysia. J Comp Physiol [A] 172:17-32.
21. Nusbaum MP, Beenhakker MP (2002) A small-systems approach to motor pattern generation. Nature 417:343-350.
22. Rekling JC, Feldman JL (1997) Calcium-dependent plateau potentials in rostral ambiguus neurons in the newborn mouse brain stem in vitro. J Neurophysiol 78:2483-2492.
23. Rubio ME, Wenthold RJ (1997) Glutamate receptors are selectively targeted to postsynaptic sites in neurons. Neuron 18:939-950.
24. Schmidt J, Calabrese RL (1992) Evidence that acetylcholine is an inhibitory transmitter of heart interneurons in the leech. J Exp Biol 171:329-347.
25. Selverston AI (1980) Are central pattern generators (CPGs) understandable? Brain Behav Sci 3:535-571.
26. Susswein AJ, Byrne JH (1988) Identification and characterization of neurons initiating patterned neural activity in the buccal ganglia of Aplysia. J Neurosci 8:2049-2061.
27. Susswein AJ, Hurwitz I, Thorne R, Byrne JH, Baxter DA (2002) Mechanisms underlying fictive feeding in Aplysia: coupling between a large neuron with plateau potentials activity and a spiking neuron. J Neurophysiol 87:2307-2323.
28. Svirskis G, Hounsgaard J (1997) Depolarization-induced facilitation of a plateau-generating current in ventral horn neurons in the turtle spinal cord. J Neurophysiol 78:1740-1742.
29. Toth K, McBain CJ (1998) Afferent-specific innervation of two distinct AMPA receptor subtypes on single hippocampal interneurons. Nat Neurosci 1:572-578.
30. Zhao HM, Wenthold RJ, Petralia RS (1998) Glutamate receptor targeting to synaptic populations on Purkinje cells is developmentally regulated. J Neurosci 18:5517-5528.