Sp1-decoy oligodeoxynucleotide inhibits high glucose-induced mesangial cell proliferation

Biochemical and Biophysical Research Communications

Volumn 319, Issue 2, 2004, Pages 550-555

  Chae, Young Mi ^a   Park, Kwan Kyu ^a   Magae, Junji ^b   Lee, In Seon ^a   Kim, Cheorl Ho ^c   Kim, Hyun Chul ^a   Hong, SaHyun ^a   Lee, Jin Gu ^a   Choi, In Jang ^a   Kim, Hyun Soo ^a   Min, Kwan Sik ^d   Lee, In Kyu ^a   Chang, Young Chae ^a  

^a Keimyung University   (South Korea)

^b INSTITUTE OF RESEARCH AND INNOVATION   (Japan)

^c Dongguk University   (South Korea)

^d Hankyong National University   (South Korea)

Author keywords

Decoy; High glucose; Mesangial cell proliferation; Plasminogen activator inhibitor 1; Sp1; Transforming growth factor 1

Indexed keywords

GLUCOSE; OLIGONUCLEOTIDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE SEQUENCE; MESANGIUM CELL; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; RAT; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; CELL DIVISION; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GLOMERULAR MESANGIUM; GLUCOSE; OLIGODEOXYRIBONUCLEOTIDES; RATS; RATS, SPRAGUE-DAWLEY; SP1 TRANSCRIPTION FACTOR;

EID: 2642578202     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.05.025     Document Type: Article

References (40)

1. Wolf G., Ziyadeh F.N. Molecular mechanisms of diabetic renal hypertrophy. Kidney Int. 56:1999;393-405
2. Steffes M.W., Bilous R.W., Sutherland D.E., Mauer S.M. Cell and matrix components of the glomerular mesangium in type I diabetes. Diabetes. 41:1992;679-684
3. Klahr S., Schreiner G., Ichikawa I. The progression of renal disease. N. Engl. J. Med. 318:1988;1657-1666
4. Jensen T. Pathogenesis of diabetic vascular disease: evidence for the role of reduced heparan sulfate proteoglycan. Diabetes. 2:1997;98-100
5. Poczatek M.H., Hugo C., Darley-Usmar V., Murphy-Ullrich J.E. Glucose stimulation of transforming growth factor-beta bioactivity in mesangial cells is mediated by thrombospondin-1. Am. J. Pathol. 157:2000;1353-1363
6. Ziyadeh F.N., Sharma K., Ericksen M., Wolf G. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta. J. Clin. Invest. 93:1994;536-542
7. Doi T., Vlassara H.M., Kirstein Y., Yamada G.E., Striker L.J. Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor. Proc. Natl. Acad. Sci. USA. 89:1992;2873-2877
8. Nahman N.S., Leonhart K.L., Cosio F.G., Hebert C.L. Effects of high glucose on cellular proliferation and fibronectin production by cultured human mesangial cells. Kidney Int. 41:1992;396-402
9. Wakisaka M., Spiro M.J., Spiro R.G. Synthesis of type VI collagen by cultured glomerular cells and comparison of its regulation by glucose and other factors with that of type IV collagen. Diabetes. 43:1994;95-103
10. Koya D., Jirousek M.R., Lin Y.W., Ishii H., Kuboki K., King G.L. Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats. J. Clin. Invest. 100:1997;115-126
11. Alroy I., Soussan L., Seger R., Yarden Y. Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factor. Mol. Cell. Biol. 19:1999;1961-1972
12. Saffer J.D., Jackson S.P., Annarella M.B. Developmental expression of Sp1 in the mouse. Mol. Cell. Biol. 11:1991;2189-2199
13. Lin S.Y., Black A.R., Kostic D., Pajovic S., Hoover C.N., Azizkhan J.C. Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction. Mol. Cell. Biol. 16:1996;1668-1675
14. Karlseder J., Rotheneder H., Wintersberger E. Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F. Mol. Cell. Biol. 16:1996;1659-1667
15. Chang Y.C., Illenye S., Heintz N.H. Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. Mol. Cell. Biol. 21:2001;1121-1131
16. Li J.M., Datto M.B., Shen X., Hu P.P., Yu Y., Wang X.F. Sp1, but not Sp3, functions to mediate promoter activation by TGF-beta through canonical Sp1 binding sites. Nucleic Acids Res. 26:1998;2449-2456
17. Datta P.K., Blake M.C., Moses H.L. Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1. J. Biol. Chem. 275:2000;40014-40019
18. Ding H., Benotmane A.M., Suske G., Collen D., Belayew A. Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene. J. Biol. Chem. 274:1999;19573-19580
19. Kim S.J., Onwuta U.S., Lee Y.I., Li R., Botchan M.R., Robbins P.D. The retinoblastoma gene product regulates Sp1-mediated transcription. Mol. Cell. Biol. 12:1992;2455-2463
20. Udvadia A.J., Rogers K.T., Higgins P.D., Murata Y., Martin K.H., Humphrey P.A., Horowitz J.M. Sp-1 Binds promoter elements regulated by the RB protein and sp-1-mediated transcription is stimulated by RB coexpression. Proc. Natl. Acad. Sci. USA. 90:1993;3265-3269
21. Udvadia A.J., Templeton D.J., Horowitz J.M. Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. Proc. Natl. Acad. Sci. USA. 92:1995;3953-3957
22. Ishibashi H., Nakagawa K., Onimaru M., Castellanous E.J., Kaneda Y., Nakashima Y., Shirasuna K., Sueishi K. Sp1 decoy transfected to carcinoma cells suppresses the expression of vascular endothelial growth factor, transforming growth factor beta1, and tissue factor and also cell growth and invasion activities. Cancer Res. 60:2000;6531-6536
23. Verrecchia F., Rossert J., Mauviel A. Blocking sp1 transcription factor broadly inhibits extracellular matrix gene expression in vitro and in vivo: implications for the treatment of tissue fibrosis. J. Invest. Dermatol. 116:2000;755-763
24. Nehls M.C., Brenner D.A., Gruss H.J., Dierbach H., Mertelsmann R., Herrmann F. Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast. J. Clin. Invest. 92:2000;2916-2921
25. Morishita R., Sugimoto T., Aoki M., Kida I., Tomita N., Moriguchi A., Maeda K., Sawa Y., Kaneda Y., Higaki J., Ogihara T. In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction. Nat. Med. 3:1997;894-899
26. Kawauchi M., Suzuki J., Morishita R., Wada Y., Izawa A., Tomita N., Amano J., Kaneda Y., Ogihara T., Takamoto S., Isobe M. Gene therapy for attenuating cardiac allograft arteriopathy using ex vivo E2F decoy transfection by HVJ-AVE-liposome method in mice and nonhuman primates. Circ. Res. 87:2000;1063-1068
27. Maeshima Y., Kashihara N., Yasuda T., Sugiyama H., Sekikawa T., Okamoto K., Kanao K., Watanabe Y., Kanwar Y.S., Makino H. Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo. J. Clin. Invest. 101:1998;2589-2597
28. Bielinska A., Shivdasani R.A., Zhang L., Nabel G.J. Reglation of gene expression with double-stranded phosphorothioate oligonucleotide. Science. 1990(250):1990;997-1000
29. Park Y.G., Nesterova M., Agrawal S., Cho-Chung Y.S. Dual blockade of cyclic AMP response element- (CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide. gene-specific inhibition of tumor growth. J. Biol. Chem. 274:1999;1573-1580
30. Ahn J.D., Morishita R., Kaneda Y., Kim H.S., Chang Y.C., Lee K.U., Park J.Y., Lee H.W., Kim Y.H., Lee I.K. Novel E2F decoy oligodeoxynucleotides inhibit in vitro vascular smooth muscle cell proliferation and in vivo neointimal hyperplasia. Gene Ther. 9:2002;1682-1692
31. Ahn J.D., Morishita R., Kaneda Y., Lee S.J., Kwon K.Y., Choi S.Y., Lee K.U., Park J.Y., Moon I.J., Park J.G., Yoshizumi M., Ouchi Y., Lee I.K. Inhibitory effects of novel AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell proliferation in vitro and neointimal formation in vivo. Circ. Res. 90:2002;1325-1332
32. Park K.K., Ahn J.D., Lee I.K., Magae J., Heintz N.H., Kwak J.Y., Lee Y.C., Cho Y.S., Kim H.C., Chae Y.M., Kim Y., Kim C.H., Chang Y.C. Inhibitory effects of novel E2F decoy oligodeoxynucleotides on mesangial cell proliferation by coexpression of E2F/DP. Biochem. Biophys. Res. Commun. 308:2003;689-697
33. Ahn J.D., Kim C.H., Magae J., Kim Y.H., Kim H.J., Park K.K., Hong S., Park K.G., Lee I.K., Chang Y.C. E2F decoy oligodeoxynucleotides effectively inhibit growth of human tumor cells. Biochem. Biophys. Res. Commun. 310:2003;1048-1053
34. Slansky J.E., Li Y., Kaelin W.G., Farnham P.J. A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter. Mol. Cell. Biol. 13:1993;1610-1618
35. Ahn J.D., Morishita R., Kaneda Y., Kim H.J., Kim Y.D., Lee H.J., Lee K.U., Park J.Y., Kim Y.H., Park K.K., Chang Y.C., Yoon K.H., Kwon H.S., Park K.G., Lee I.K. Transcription factor decoy for AP-1 reduces mesangial cell proliferation and extracellular matrix production in vitro and in vivo. Gene Ther. 2004;. (Epub ahead of print)
36. Ihn H., Ihn Y., Trojanowska M. Sp1 phosphorylation induced by serum stimulates the human 2(I) collagen gene expression. J. Invest. Dermatol. 117:2001;301-308
37. Suske G. The Sp-family of transcription factors. Gene. 238:1999;291-300
38. Border W.A., Noble N.A. TGF-β1 in kidney fibrosis: a target for gene therapy. Kidney Int. 51:1997;1388-1396
39. Datta P.K., Blake M.C., Moses H.L. Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-β-induced physical and functional interactions between Smads and Sp1. J. Biol. Chem. 275:2000;40014-40019
40. Mooney A., Jackson K., Bacon R., Streuli C., Edwards G., Bassuk J., Savill J. Type IV collagen and laminin regulate glomerular mesangial cell susceptibility to apoptosis via beta(1) integrin-mediated survival signals. Am. J. Pathol. 155:1999;599-606