-
1
-
-
0033786776
-
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
-
Bielekova B., Goodwin B., Richert N., Cortese I., Kondo T., Afshar G., et al. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat. Med. 6:2000;1167-1175
-
(2000)
Nat. Med.
, vol.6
, pp. 1167-1175
-
-
Bielekova, B.1
Goodwin, B.2
Richert, N.3
Cortese, I.4
Kondo, T.5
Afshar, G.6
-
2
-
-
0029019568
-
T cell recognition of immunodominant and cryptic proteolipid protein epitopes in humans
-
Markovic-Plese S., Fukuara H., Zhang J., al-Sabbagh A., Southwood S., Sette A., et al. T cell recognition of immunodominant and cryptic proteolipid protein epitopes in humans. J. Immunol. 155:1995;982-992
-
(1995)
J. Immunol.
, vol.155
, pp. 982-992
-
-
Markovic-Plese, S.1
Fukuara, H.2
Zhang, J.3
Al-Sabbagh, A.4
Southwood, S.5
Sette, A.6
-
3
-
-
0027957780
-
Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
-
Zhang J., Markovic-Plese S., Lacet B., Raus J., Weiner H., Hafler D. Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J. Exp. Med. 179:1994;973-984
-
(1994)
J. Exp. Med.
, vol.179
, pp. 973-984
-
-
Zhang, J.1
Markovic-Plese, S.2
Lacet, B.3
Raus, J.4
Weiner, H.5
Hafler, D.6
-
4
-
-
0025981021
-
T-lymphocyte entry into the central nervous system
-
Hickey W., Hsu B., Kimura H. T-lymphocyte entry into the central nervous system. J. Neurosci. Res. 28:1991;254-260
-
(1991)
J. Neurosci. Res.
, vol.28
, pp. 254-260
-
-
Hickey, W.1
Hsu, B.2
Kimura, H.3
-
5
-
-
0032171644
-
A very high level of crossreactivity is an essential feature of the T-cell receptor
-
Mason D. A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol. Today. 19:1998;395-404
-
(1998)
Immunol. Today
, vol.19
, pp. 395-404
-
-
Mason, D.1
-
6
-
-
10244247768
-
Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99)
-
Vergelli M., Hemmer B., Utz U., Vogt A., Kalbus M., Tranquill L., et al. Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99). Eur. J. Immunol. 26:1996;2624-2634
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 2624-2634
-
-
Vergelli, M.1
Hemmer, B.2
Utz, U.3
Vogt, A.4
Kalbus, M.5
Tranquill, L.6
-
7
-
-
0031966527
-
Probing degeneracy in T-cell recognition using peptide combinatorial libraries
-
Hemmer B., Vergelli M., Pinilla C., Houghten R., Martin R. Probing degeneracy in T-cell recognition using peptide combinatorial libraries. Immunol. Today. 19:1998;163-168
-
(1998)
Immunol. Today
, vol.19
, pp. 163-168
-
-
Hemmer, B.1
Vergelli, M.2
Pinilla, C.3
Houghten, R.4
Martin, R.5
-
8
-
-
0027333348
-
Tickling the TCR: Selective T-cell functions stimulated by altered peptide ligands
-
Evavold B., Sloan-Lancaster J., Allen P. Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands. Immunol. Today. 14:1993;602-609
-
(1993)
Immunol. Today
, vol.14
, pp. 602-609
-
-
Evavold, B.1
Sloan-Lancaster, J.2
Allen, P.3
-
9
-
-
0034979369
-
Molecular mimicry and antigen-specific T cell responses in multiple sclerosis and chronic CNS Lyme disease
-
Martin R., Gran B., Zhao Y., Markovic-Plese S., Bielekova B., Marques A., et al. Molecular mimicry and antigen-specific T cell responses in multiple sclerosis and chronic CNS Lyme disease. J. Autoimmun. 16:2001;187-192
-
(2001)
J. Autoimmun.
, vol.16
, pp. 187-192
-
-
Martin, R.1
Gran, B.2
Zhao, Y.3
Markovic-Plese, S.4
Bielekova, B.5
Marques, A.6
-
10
-
-
0027468174
-
Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity
-
Goverman J., Woods A., Larson L., Weiner L., Hood L., Zaller D. Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell. 72:1993;551-560
-
(1993)
Cell
, vol.72
, pp. 551-560
-
-
Goverman, J.1
Woods, A.2
Larson, L.3
Weiner, L.4
Hood, L.5
Zaller, D.6
-
11
-
-
0035881251
-
Combinatorial peptide libraries and biometric score matrices permit the quantitative analysis of specific and degenerate interactions between clonotypic TCR and MHC peptide ligands
-
Zhao Y., Gran B., Pinilla C., Markovic-Plese S., Hemmer B., Tzou A., et al. Combinatorial peptide libraries and biometric score matrices permit the quantitative analysis of specific and degenerate interactions between clonotypic TCR and MHC peptide ligands. J. Immunol. 167:2001;2130-2141
-
(2001)
J. Immunol.
, vol.167
, pp. 2130-2141
-
-
Zhao, Y.1
Gran, B.2
Pinilla, C.3
Markovic-Plese, S.4
Hemmer, B.5
Tzou, A.6
-
12
-
-
0032728738
-
Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease
-
Hemmer B., Gran B., Zhao Y., Marques A., Pascal J., Tzou A., et al. Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease. Nat. Med. 5:1999;1375-1382
-
(1999)
Nat. Med.
, vol.5
, pp. 1375-1382
-
-
Hemmer, B.1
Gran, B.2
Zhao, Y.3
Marques, A.4
Pascal, J.5
Tzou, A.6
-
13
-
-
18444410234
-
Findings on T cell specificity revealed by synthetic combinatorial libraries
-
Borras E., Martin R., Judkowski V., Shukaliak J., Zhao Y., Rubio-Godoy V., et al. Findings on T cell specificity revealed by synthetic combinatorial libraries. J. Immunol. Methods. 267:2002;79-97
-
(2002)
J. Immunol. Methods
, vol.267
, pp. 79-97
-
-
Borras, E.1
Martin, R.2
Judkowski, V.3
Shukaliak, J.4
Zhao, Y.5
Rubio-Godoy, V.6
-
14
-
-
0033964373
-
Paradoxical inhibition of T-cell function in response to CTLA-4 blockade heterogeneity within the human T-cell population
-
Anderson D., Bieganowska K., Bar-Or A., Oliveira E., Carreno B., Collins M., et al. Paradoxical inhibition of T-cell function in response to CTLA-4 blockade heterogeneity within the human T-cell population. Nat. Med. 6:2000;211-214
-
(2000)
Nat. Med.
, vol.6
, pp. 211-214
-
-
Anderson, D.1
Bieganowska, K.2
Bar-Or, A.3
Oliveira, E.4
Carreno, B.5
Collins, M.6
-
15
-
-
0028979466
-
New perspectives of CD28-B7-mediated T cell costimulation
-
Bluestone J. New perspectives of CD28-B7-mediated T cell costimulation. Immunity. 2:1995;555-559
-
(1995)
Immunity
, vol.2
, pp. 555-559
-
-
Bluestone, J.1
-
16
-
-
0034642534
-
Cbl-b regulates the CD28 dependence of T-cell activation
-
Chiang Y., Kole H., Brown K., Naramura M., Fukuhara S., Hu R., et al. Cbl-b regulates the CD28 dependence of T-cell activation. Nature. 403:2000;216-220
-
(2000)
Nature
, vol.403
, pp. 216-220
-
-
Chiang, Y.1
Kole, H.2
Brown, K.3
Naramura, M.4
Fukuhara, S.5
Hu, R.6
-
17
-
-
0034642499
-
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
-
Bachmaier K., Krawczyk C., Kozieradzki I., Kong Y., Sasaki T., Oliveira-dos-Santos A., et al. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature. 403:2000;211-216
-
(2000)
Nature
, vol.403
, pp. 211-216
-
-
Bachmaier, K.1
Krawczyk, C.2
Kozieradzki, I.3
Kong, Y.4
Sasaki, T.5
Oliveira-Dos-Santos, A.6
-
18
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol E., Borriello F., Schweitzer A., Lynch W., Bluestone J., Sharpe A. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity. 3:1995;541-547
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.1
Borriello, F.2
Schweitzer, A.3
Lynch, W.4
Bluestone, J.5
Sharpe, A.6
-
19
-
-
0034773579
-
CD4+ CD28- costimulation-independent T cells in multiple sclerosis
-
Markovic-Plese S., Cortese I., Wandinger K., McFarland H., Martin R. CD4+ CD28- costimulation-independent T cells in multiple sclerosis. J. Clin. Invest. 108:2001;1185-1194
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1185-1194
-
-
Markovic-Plese, S.1
Cortese, I.2
Wandinger, K.3
McFarland, H.4
Martin, R.5
-
20
-
-
0029958821
-
CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity
-
Schmidt D., Goronzy J., Weyand C. CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J. Clin. Invest. 97:1996;2027-2037
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2027-2037
-
-
Schmidt, D.1
Goronzy, J.2
Weyand, C.3
-
21
-
-
0034544566
-
Clonality and longevity of CD4+CD28null T cells are associated with defects in apoptotic pathways
-
Vallejo A., Schirmer M., Weyand C., Goronzy J. Clonality and longevity of CD4+CD28null T cells are associated with defects in apoptotic pathways. J. Immunol. 165:2000;6301-6307
-
(2000)
J. Immunol.
, vol.165
, pp. 6301-6307
-
-
Vallejo, A.1
Schirmer, M.2
Weyand, C.3
Goronzy, J.4
-
22
-
-
0035153212
-
Immune function of astrocytes
-
Dong Y., Benveniste E. Immune function of astrocytes. Glia. 36:2001;180-190
-
(2001)
Glia
, vol.36
, pp. 180-190
-
-
Dong, Y.1
Benveniste, E.2
-
24
-
-
0034237416
-
Role of astrocytes in antigen presentation and naive T-cell activation
-
Cornet A., Bettelli E., Oukka M., Cambouris C., Avellana-Adalid V., Kosmatopoulos K., et al. Role of astrocytes in antigen presentation and naive T-cell activation. J. Neuroimmunol. 106:2000;69-77
-
(2000)
J. Neuroimmunol.
, vol.106
, pp. 69-77
-
-
Cornet, A.1
Bettelli, E.2
Oukka, M.3
Cambouris, C.4
Avellana-Adalid, V.5
Kosmatopoulos, K.6
-
25
-
-
0035063937
-
Specificity and degeneracy in antigen recognition: Yin and yang in the immune system
-
Eisen H. Specificity and degeneracy in antigen recognition: yin and yang in the immune system. Annu. Rev. Immunol. 19:2001;1-21
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 1-21
-
-
Eisen, H.1
-
26
-
-
0035554905
-
Immunotherapy of multiple sclerosis: Where are we? Where should we go?
-
Martin R., Sturzebecher C., McFarland H. Immunotherapy of multiple sclerosis: where are we? Where should we go? Nature. 9:2001;785-788
-
(2001)
Nature
, vol.9
, pp. 785-788
-
-
Martin, R.1
Sturzebecher, C.2
McFarland, H.3
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