Intact glycans from cestode antigens are involved in innate activation of myeloid suppressor cells

Parasite Immunology

Volumn 27, Issue 10-11, 2005, Pages 395-405

  Gomez Garcia L ^a,b   Lopez Marin L M ^b   Saavedra, R ^b   Reyes, J L ^a   Rodriguez Sosa M ^a   Terrazas, Luis I ^a,b  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Cysticercosis; Glycans; Gr1+; Helminth; Suppressor cells

Indexed keywords

CARBOHYDRATE; CD28 ANTIGEN; CD3 ANTIGEN; GLYCAN DERIVATIVE; MONOCLONAL ANTIBODY; PARASITE ANTIGEN; PERIODATE SODIUM; PROTEIN; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CELL CONTACT; CELL POPULATION; CELL PROLIFERATION; CESTODE; CESTODIASIS; CONTROLLED STUDY; FEMALE; IMMUNOMODULATION; IMMUNOREGULATION; IMMUNOSTIMULATION; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MOUSE; MOUSE STRAIN; NEMATODE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPPRESSOR CELL; T LYMPHOCYTE; TAENIA CRASSICEPS; TH2 CELL; TREMATODE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD28; ANTIGENS, CD3; ANTIGENS, DIFFERENTIATION; ANTIGENS, HELMINTH; CESTODA; CESTODE INFECTIONS; COCULTURE TECHNIQUES; CYTOKINES; FEMALE; FLOW CYTOMETRY; MICE; MYELOID CELLS; POLYSACCHARIDES; RECEPTORS, CHEMOKINE; TOLL-LIKE RECEPTOR 4;

CESTODA; TAENIA CRASSICEPS; TREMATODA; VERMES;

EID: 26244463346     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2005.00790.x     Document Type: Article

References (41)

1. Maizels RM & Yazdanbakhsh M. Immune regulation by helminth parasites: cellular and molecular mechanisms. Nat Rev Immunol 2003; 3: 733-744.
2. Maizels RM et al. Helminth parasites - masters of regulation. Immunol Rev 2004; 201: 89-116.
3. Harnett W, McInnes IB & Harnett MM. ES-62, a filarial nematode-derived immunomodulator with anti-inflammatory potential. Immunol Lett 2004; 94: 27-33.
4. Goodridge HS et al. Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae. J Immunol 2001; 167: 940-945.
5. Cause WC, Urban JF Jr & Stadecker MJ. The immune response to parasitic helminths: insights from murine models. Trends Immunol 2003; 24: 269-277.
6. Terrazas LI et al. Taenia crassiceps cysticercosis: a role for prostaglandin E2 in susceptibility. Parasitol Res 1999; 85: 1025-1031.
7. Rodríguez-Sosa M, Satoskar AR, Calderón R et al. Chronic helminth infection induces alternatively activated macrophages expressing high levels of CCR5 with low interleukin 12 production and Th2-biasing ability. Infect Immun 2002; 70: 3656-3664.
8. Rodríguez-Sosa M, Satoskar AR, David JR & Terrazas LI. Altered T-helper responses in CD40 and interleukin 12-deficient mice reveal a critical role for Th1 responses in eliminating the helminth parasite Taenia crassiceps. Int J Parasitol 2003; 33: 703-711.
9. Terrazas LI, Bojalil R, Govezensky T & Larralde C. Shift from an early protective Th1-type immune response to a late permissive Th2-type response in murine cysticercosis (Taenia crassiceps). J Parasitol 1998; 84: 74-81.
10. Villa OF & Kühn RE. Mice infected with the larvae of Taenia crassiceps exhibit a Th2-like immune response with concomitant anergy and down-regulation of Th1-associated phenomena. Parasitology 1996; 112: 561-570.
11. Rodríguez-Sosa M, David JR, Bojalil R et al. Cutting edge: susceptibility to the larval stage of the helminth parasite Taenia crassiceps is mediated by Th2 response induced via STAT6 signaling. J Immunol 2002; 168: 3135-3139.
12. Sciutto E, Fragoso G, Vaca M et al. Depressed T-cell proliferation associated with susceptibility to experimental Taenia crassiceps infection. Infect Immun 1995; 63: 2277-2281.
13. Rodríguez M, Terrazas LI, Marquez R & Bojalil R. Susceptibility to Trypanosoma cruzi is modified by a previous nonrelated infection. Parasite Immunol 1999; 21: 177-185.
14. Spolski RJ, Alexander-Miller MA & Kuhn RE. Suppressed cytotoxic T-lymphocyte responses in experimental cysticercosis. Vet Parasitol 2002; 106: 325-330.
15. Whelan M, Harnett MM, Houston KM et al. A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells. J Immunol 2000; 164: 6453-6460.
16. Gregory WF, Atmadja AK, Allen JE et al. The abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis. Infect Immun 2000; 68: 4174-4179.
17. Holland MJ et al. Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses. Eur J Immunol 2000; 30: 1977-1987.
18. Holland MJ, Harcus YM, Balic A et al. Th2 induction by Nippostrongylus-secreted antigens in mice deficient in B cells, eosinophils or MHC class I-related receptors. Immunol Lett 2005; 96: 93-101.
19. Ishida MM, Rubinsky-Elefant G, Ferreira S et al. Helminth antigens (Taenia solium, Taenia crassiceps, Toxocara canis, Schistosoma mansoni and Echinococcus granulosus) and cross-reactivities in human infections and immunized animals. Acta Trop 2003; 89: 73-84.
20. Obregón-Henao A, Londono DP, Gomez DI et al. The role of N-linked carbohydrates in the antigenicity of Taenia solium metacestode glycoproteins of 12, 16 and 18 kD. Mol Biochem Parasitol 2001; 114: 209-215.
21. Okano M, Satoskar AR, Nishizaki M et al. Induction of Th2 responses and IgE is largely due to carbohydrates functioning as adjuvants on Schistosoma mansoni egg antigens. J Immunol 1999; 163: 6712-6717.
22. Tawill S, Le Goff L, Ali F, Blaxter M, & Allen JE. Both free-living and parasitic nematodes induce a characteristic Th2 response that is dependent on the presence of intact glycans. Infect Immun 2004; 72: 398-407.
23. Terrazas LI, Walsh KL, Piskorska D et al. The schistosome oligosaccharide lacto-n-neotetraose expands grl(+) cells that secrete anti-inflammatory cytokines and inhibit proliferation of naive cd4(+) cells: a potential mechanism for immune polarization in helminth infections. J Immunol 2001; 167: 5294-5303.
24. Atochina O, Daly-Engel T, Piskorska D et al. A schistosome-expressed immunomodulatory glycoconjugate expands peritoneal Grl(+) macrophages that suppress naive CD4(+) T-cell proliferation via an IFN-gamma and nitric oxide-dependent mechanism. J Immunol 2001; 167: 4293-4302.
25. Nair MG, Gallagher IJ, Taylor MD et al. Chitinase and Fizz family members are a generalized feature of nematode infection with selective up-regulation of Ym1 and Fizz1 by antigen-presenting cells. Infect Immun 2005; 73: 385-394.
26. Deehan MR, Harnett W & Harnett MM. A filarial nematode-secreted phosphorylcholine-containing glycoprotein uncouples the B-cell antigen receptor from extracellular signal-regulated kinase-mitogen-activated protein kinase by promoting the surface Ig-mediated recruitment of Src homology 2 domain-containing tyrosine phosphatase-1 and Pac-1 mitogen-activated kinase-phosphatase. J Immunol 2001; 166: 7462-7468.
27. Gruden-Movsesijan A, Ilic N & Sofronic-Milosavljevic L. Lectin-blot analyses of Trichinella spiralis muscle larvae excretory-secretory components. Parasitol Res 2002; 88: 1004-1007.
28. + cells: a potential mechanism for immune polarization in helminth infections. J Immunol 2001; 167: 5294-5303.
29. + myeloid cells and anergy of T lymphocytes participate in hyporesponsiveness of the lung-associated immune system during acute toxoplasmosis. Infect Immun 2004; 72: 5487-5492.
30. Sinha P, Clements VK & Ostrand-Rosenberg S. Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J Immunol 2005; 174: 636-645.
31. Brys L, Beschin A, Raes G et al. Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection. J Immunol 2005; 174: 6095-6104.
32. Thomas PG, Carter MR, Atochina O et al. Maturation of dendritic cell 2 phenotype by a helminth glycan uses a toll-like receptor 4-dependent mechanism. J Immunol 2003; 171: 5837-5841.
33. Goodridge HS, Marshal FA, Else KJ et al. Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62. J Immunol 2005; 174: 284-293.
34. Goni O, Alcaide P & Fresno M. Immunosuppression during acute Trypanosoma cruzi infection, involvement of Ly6G (Gr1(+) CD11b(+) immature myeloid suppressor cells. Int Immunol 2002; 14: 1125-1134.
35. Salvadori S, Martinelli G & Zier K. Resection of solid tumors reverses T-cell defects and restores protective immunity. J Immunol 2000; 164: 2214-2220.
36. Smith P, Wals CM, Mangan NE et al. Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J Immunol 2004; 173: 1240-1248.
37. Allen JE & Loke P. Divergent roles for macrophages in lymphatic filariasis. Parasite Immunol 2001; 23: 345-352.
38. MacDonald AS et al. Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. J Immunol 1998; 160: 1304-1312.
39. + splenocytes undergo apoptosis during an experimental murine infection with Taenia crassiceps. Parasitol Res 2003; 90: 157-163.
40. Allen JE, Lawrence RA & Maizels RM. APC from mice harbouring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production. Int Immunol 1996; 8: 143-151.
41. Akira S, Takeda K & Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001; 2: 675-680.