Influence of process parameters on the size distribution of PLA microcapsules prepared by combining membrane emulsification technique and double emulsion-solvent evaporation method

Colloids and Surfaces B: Biointerfaces

Volumn 45, Issue 3-4, 2005, Pages 144-153

  Liu, Rong ^a   Ma, Guang Hui ^a   Wan, Yin Hua ^a   Su, Zhi Guo ^a  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

Author keywords

Double emulsion solvent evaporation; Membrane emulsification; Poly(lactide); Size distribution

Indexed keywords

EMULSIFICATION; GLASS MEMBRANE ELECTRODES; ORGANIC POLYMERS; PARTICLE SIZE ANALYSIS;

DOUBLE EMULSION-SOLVENT EVAPORATION; MEMBRANE EMULSIFICATION; POLY(LACTIDE); SIZE DISTRIBUTION;

EMULSIONS;

DICHLOROMETHANE; NITROGEN; OIL; POLYLACTIDE; POLYMER; RECOMBINANT HUMAN INSULIN; SOLVENT; SORBITAN ESTER; TOLUENE; WATER;

ADSORPTION; ARTICLE; DRUG RELEASE; EMULSION; EVAPORATION; MICROCAPSULE; MICROENCAPSULATION; PARAMETER; PRIORITY JOURNAL; TECHNIQUE;

CAPSULES; EMULSIONS; GLASS; MEMBRANES, ARTIFICIAL; OILS; PARTICLE SIZE; POLYESTERS; POROSITY; SOLVENTS; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS; VOLATILIZATION; WATER;

EID: 26244458325     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2005.08.004     Document Type: Article

References (21)

1. M.N. Vrancken, D.A. Clays, Method for encapsulating water and compounds in aqueous phase by extraction, United States Patent Office 3,526,906 (1970).
2. N.C. Jaeger, B.H. Trvernier, British Patent 1,405,108 (1971).
3. M. Kitajima, and A. Kondo Fermentation without multiplication of cells using microparticles that contain zymase complex and muscle enzyme extract Bull. Chem. Soc. Jpn. 44 1971 3201 3202
4. Y. Ogawa, M. Yamamoto, S. Takada, H. Okada, and T. Shimamoto Controlled-release of leuprolide acetate from polylactic acid or copoly(lactic/glycolic) acid microparticles: influence of molecular weight and copolymer ratio of polymer Chem. Pharm. Bull. 36 1988 1502 1507
5. M.E. Le Fevre, D.C. Hancock, and D.D. Joel Intestinal barrier to large particulates in mice J. Toxicol. Environ. Health 6 1980 691 704
6. G.H. Ma, M. Nagai, and S. Omi Preparation of uniform poly (lactide) microspheres by employing the Shirasu porous glass (SPG) emulsification technique Colloids Surf. A: Physicochem. Eng. Aspects 153 1999 383 394
7. T. Nakashima, M. Shimizu, and M. Kukizaki Membrane emulsification by microporous glass Key Eng. Mater. 61/62 1991 513 516
8. G.H. Ma, M. Nagai, and S. Omi Effect of lauryl alcohol on morphology of uniform polystyrene-poly (methyl methacrylate) composite microspheres prepared by porous glass membrane emulsification technique J. Colloid Interface Sci. 219 1999 110 128
9. H. Yuyama, T. Watanabe, G.H. Ma, M. Nagai, and S. Omi Preparation and analysis of uniform emulsion droplets using SPG membrane emulsification technique Colloids Surf. A: Physicochem. Eng. Aspects 168 2000 159 174
10. G.H. Ma, M. Nagai, and S. Omi Study on preparation and morphology of uniform artificial polystyrene-poly (methyl methacrylate) composite microspheres by employing the SPG (Shirasu porous Glass) membrane emulsification technique J. Colloid Interface Sci. 214 1999 264 282
11. G.H. Ma, M. Nagai, and S. Omi Synthesis of uniform microspheres with higher content of 2-hydroxyethyl methacrylate by employing SPG (Shirasu porous glass) emulsification technique followed by swelling process of droplets J. Appl. Polym. Sci. 66 1997 1325 1341
12. G.H. Ma, H. Sone, and S. Omi Preparation of uniform-sized polystyrene-polyacrylamide composite microspheres from a w/o/w emulsion by membrane emulsification technique and subsequent suspension polymerization Macromolecules 37 2004 2954 2964
13. R. Liu, G.H. Ma, F.T. Meng, and Z.G. Su Preparation of uniform-sized PLA microcapsules by combining Shirasu porous glass (SPG) membrane emulsification technique and multiple emulsion-solvent evaporation method J. Control. Release. 103 2005 31 43
14. N. Wakiyama, K. Juni, and M. Nakano Preparation and evaluation in vitro and in vivo of polylactic acid microspheres containing dibucaine Chem. Pharm. Bull. 30 1982 3719 3727
15. B.V. Parikh, S.M. Upadrashta, S.H. Neau, and N.O. Nuessle Oestrone loaded poly(l-lactic acid) microspheres: preparation, evaluation and in vitro release kinetics J. Microencapsul. 10 1993 141 153
16. M. Singh, and D. O'Hagan The preparation and characterization of polymeric antigen delivery systems for oral administration Adv. Drug Del. Rev. 34 1998 285 304
17. R.A. Williams, S.J. Peng, D.A. Wheeler, N.C. Morley, D. Taylor, M. Whalley, and D.W. Houldsworth Controlled production of emulsions using a crossflow membrane. Part II. Industrial scale manufacture Chem. Eng. Res. Des. 76A 8 1998 902 910
18. V. Schröder, O. Behrend, and H. Schubert Effect of dynamic interfacial tension on the emulsification process using microporous, ceramic membranes J. Colloid Interface Sci. 202 1998 334 340
19. N.C. Christov, D.N. Ganchev, N.D. Denkov, K.D. Danov, and P.A. Kralchevsky Capillary mechanisms in membrane emulsification: oil-in-water emulsions stabilized by Tween 20 and milk proteins Colloids Surf. A 209 2002 83 104
20. T. Nakashima, M. Shimizu, and M. Kukizaki Particle control of emulsion by membrane emulsification and its applications Adv. Drug Del. Rev. 45 2000 47 56
21. K.A. Athanasiou, G.G. Niederauer, and C.M. Agrawal Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers Biomaterials 17 1996 93 102