메뉴 건너뛰기




Volumn 22, Issue 7, 2005, Pages 605-611

The pharmacokinetic effect of discontinuation of mesalazine on mercaptopurine metabolite levels in inflammatory bowel disease patients

Author keywords

[No Author keywords available]

Indexed keywords

6 METHYLTHIOINOSINE; DRUG METABOLITE; MERCAPTOPURINE; MESALAZINE; THIOPURINE METHYLTRANSFERASE; TIOGUANINE;

EID: 26244455766     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2005.02630.x     Document Type: Article
Times cited : (65)

References (30)
  • 1
    • 0036444324 scopus 로고    scopus 로고
    • Initial therapy for mild to moderate Crohn's disease: Mesalamine or budenoside?
    • Feagan BG, Sandborn WJ. Initial therapy for mild to moderate Crohn's disease: mesalamine or budenoside? Rev Gastroenterol Disord 2002; 2 (Suppl. 2): S9-15.
    • (2002) Rev Gastroenterol Disord , vol.2 , Issue.SUPPL. 2
    • Feagan, B.G.1    Sandborn, W.J.2
  • 2
    • 0033975599 scopus 로고    scopus 로고
    • Immunopharmacology of 5-aminosalicylic acid and of glucocorticoids in the therapy of inflammatory bowel disease
    • Nikolaus S, Folscn U, Schreiber S. Immunopharmacology of 5-aminosalicylic acid and of glucocorticoids in the therapy of inflammatory bowel disease. Hepatogastroenterology 2000; 47: 71-82.
    • (2000) Hepatogastroenterology , vol.47 , pp. 71-82
    • Nikolaus, S.1    Folscn, U.2    Schreiber, S.3
  • 3
    • 0141613180 scopus 로고    scopus 로고
    • Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis
    • CD000543
    • Sutherland L, MacDonald JK. Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database Syst Rev 2003; 3: CD000543.
    • (2003) Cochrane Database Syst Rev , vol.3
    • Sutherland, L.1    MacDonald, J.K.2
  • 5
    • 0030775667 scopus 로고    scopus 로고
    • Mesalamine in the maintenance treatment of Crohn's disease: A meta-analysis adjusted for confounding variables
    • Cama C, Giunta M, Rosselli M, Cottone M. Mesalamine in the maintenance treatment of Crohn's disease: a meta-analysis adjusted for confounding variables. Gastroenterology 1997; 113: 1465-73.
    • (1997) Gastroenterology , vol.113 , pp. 1465-1473
    • Cama, C.1    Giunta, M.2    Rosselli, M.3    Cottone, M.4
  • 6
    • 0033965199 scopus 로고    scopus 로고
    • Prophylaxis of postoperative relapse in Crohn's disease with mesalamine: European Cooperative Crohn's Disease Study VI
    • Lochs H, Mayer M, Fleig WE, et al. Prophylaxis of postoperative relapse in Crohn's disease with mesalamine: European Cooperative Crohn's Disease Study VI. Gastroenterology 2000; 118: 264-73.
    • (2000) Gastroenterology , vol.118 , pp. 264-273
    • Lochs, H.1    Mayer, M.2    Fleig, W.E.3
  • 7
    • 2342433583 scopus 로고    scopus 로고
    • Oral Pentasa in the treatment of active Crohn's disease: A meta-analysis of double-blind, placebo-controlled trials
    • Hanauer SB, Stromberg U. Oral Pentasa in the treatment of active Crohn's disease: a meta-analysis of double-blind, placebo-controlled trials. Clin Gastroenterol Hepatol 2004; 2: 379-88.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 379-388
    • Hanauer, S.B.1    Stromberg, U.2
  • 8
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis
    • Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 2001; 48: 526-35.
    • (2001) Gut , vol.48 , pp. 526-535
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 9
    • 0036820724 scopus 로고    scopus 로고
    • Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency
    • Sumi S, Marinaki A, Arenas M, et al. Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency. Hum Genet 2002; 111: 360-7.
    • (2002) Hum Genet , vol.111 , pp. 360-367
    • Sumi, S.1    Marinaki, A.2    Arenas, M.3
  • 10
    • 12144285961 scopus 로고    scopus 로고
    • Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase)
    • Marinaki AM, Ansari A, Duley JA, et al. Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). Pharmacogenetics 2004; 14: 181-7.
    • (2004) Pharmacogenetics , vol.14 , pp. 181-187
    • Marinaki, A.M.1    Ansari, A.2    Duley, J.A.3
  • 12
    • 0029794073 scopus 로고    scopus 로고
    • 6-Mercaptopurine metabolism in Crohn's disease: Correlation with efficacy and toxicity
    • Cuffari C, Theoret Y, Latour S, et al. 6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity. Gut 1996; 39: 401-6.
    • (1996) Gut , vol.39 , pp. 401-406
    • Cuffari, C.1    Theoret, Y.2    Latour, S.3
  • 13
    • 0034067784 scopus 로고    scopus 로고
    • Pharmacogenomic and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
    • Dubinsky MC, Lamothe S, Yang HY, et al. Pharmacogenomic and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000; 118: 705-13.
    • (2000) Gastroenterology , vol.118 , pp. 705-713
    • Dubinsky, M.C.1    Lamothe, S.2    Yang, H.Y.3
  • 14
    • 16444367834 scopus 로고    scopus 로고
    • 6-Tioguanine monitoring in steroid dependent patients with inflammatory bowel diseases receiving azathioprine
    • Roblin X, Serre-Debeaubais F, Phelip JM, et al 6-Tioguanine monitoring in steroid dependent patients with inflammatory bowel diseases receiving azathioprine. Aliment Pharmacol Ther 2005; 21: 829-39.
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 829-839
    • Roblin, X.1    Serre-Debeaubais, F.2    Phelip, J.M.3
  • 15
    • 0033862234 scopus 로고    scopus 로고
    • Enhanced bioavailability of azathioprine compared to 6-mercaptopurine therapy in inflammatory bowel disease: Correlation with treatment efficacy
    • Cuffari C, Hunt S, Bayless T. Enhanced bioavailability of azathioprine compared to 6-mercaptopurine therapy in inflammatory bowel disease: correlation with treatment efficacy. Aliment Pharmacol Ther 2000; 14: 1009-14.
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 1009-1014
    • Cuffari, C.1    Hunt, S.2    Bayless, T.3
  • 16
    • 0034771188 scopus 로고    scopus 로고
    • Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
    • Lowry PW, Franklin CL, Weaver AL, et al. Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. Gut 2001; 49: 665-70.
    • (2001) Gut , vol.49 , pp. 665-670
    • Lowry, P.W.1    Franklin, C.L.2    Weaver, A.L.3
  • 17
    • 0035186469 scopus 로고    scopus 로고
    • 6-Mercaptopurine (6MP) metabolite levels in children with IBD
    • Gupta P, Gokhale R, Kirschner B. 6-Mercaptopurine (6MP) metabolite levels in children with IBD. J Pediatr Gastroenterol Nutr 2001; 33: 450-4.
    • (2001) J Pediatr Gastroenterol Nutr , vol.33 , pp. 450-454
    • Gupta, P.1    Gokhale, R.2    Kirschner, B.3
  • 18
    • 0036202803 scopus 로고    scopus 로고
    • 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
    • Dubinsky MC, Yang H, Hassard PV, et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology 2002; 122: 904-15.
    • (2002) Gastroenterology , vol.122 , pp. 904-915
    • Dubinsky, M.C.1    Yang, H.2    Hassard, P.V.3
  • 19
    • 3242762099 scopus 로고    scopus 로고
    • Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants
    • Schaeffeler E, Fischer C, Brockmeier D, et al. Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants. Pharmacogenetics 2004; 14: 407-17.
    • (2004) Pharmacogenetics , vol.14 , pp. 407-417
    • Schaeffeler, E.1    Fischer, C.2    Brockmeier, D.3
  • 20
    • 0032212759 scopus 로고    scopus 로고
    • Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine
    • Black AJ, McLeod HL, Capell HA. Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine. Ann Intern Med 1998; 129: 716-8.
    • (1998) Ann Intern Med , vol.129 , pp. 716-718
    • Black, A.J.1    McLeod, H.L.2    Capell, H.A.3
  • 21
    • 0031663491 scopus 로고    scopus 로고
    • Clinical implications of thiopurine methyltransferase - Optimization of drug dosage and potential drug interactions
    • Lennard L. Clinical implications of thiopurine methyltransferase - optimization of drug dosage and potential drug interactions. Ther Drug Monit 1998; 20: 527-31.
    • (1998) Ther Drug Monit , vol.20 , pp. 527-531
    • Lennard, L.1
  • 22
    • 2542639314 scopus 로고    scopus 로고
    • Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease; implications for therapy
    • Derijks LJJ, Gilissen LPL, Engels LGJB, et al. Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease; implications for therapy. Ther Drug Monit 2004; 26: 311-8.
    • (2004) Ther Drug Monit , vol.26 , pp. 311-318
    • Derijks, L.J.J.1    Gilissen, L.P.L.2    Engels, L.G.J.B.3
  • 23
    • 0030027378 scopus 로고    scopus 로고
    • Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide
    • Lysaa RA, Giverhaug T, Wold HL, Aarbakke J. Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide. Eur J Pharmacol 1996; 49: 393-6.
    • (1996) Eur J Pharmacol , vol.49 , pp. 393-396
    • Lysaa, R.A.1    Giverhaug, T.2    Wold, H.L.3    Aarbakke, J.4
  • 24
    • 0028917479 scopus 로고
    • Sulphasalazine inhibition of thiopurine methyltransferase: Possible mechanism for interaction with 6-mercaptopurine and azathioprine
    • Szumlanski CL, Weinshilboum RM. Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6-mercaptopurine and azathioprine. Br J Clin Pharmacol 1995; 39: 456-9.
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 456-459
    • Szumlanski, C.L.1    Weinshilboum, R.M.2
  • 25
    • 0030657957 scopus 로고    scopus 로고
    • Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction
    • Lewis LD, Benin A, Szumlanski CL, et al. Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction. Clin Pharmacol Ther 1997; 62: 464-75.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 464-475
    • Lewis, L.D.1    Benin, A.2    Szumlanski, C.L.3
  • 26
    • 0034780344 scopus 로고    scopus 로고
    • Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine or balsalazide
    • Lowry PW, Franklin CL, Weaver AL, et al. Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine or balsalazide. Gut 2001; 49: 656-64.
    • (2001) Gut , vol.49 , pp. 656-664
    • Lowry, P.W.1    Franklin, C.L.2    Weaver, A.L.3
  • 27
    • 0036161781 scopus 로고    scopus 로고
    • Interaction between azathioprine and aminosalicylates: An in vivo study in patients with Crohn's disease
    • Dewit O, Vanheuverzwyn R, Desager JP, Horsmans Y. Interaction between azathioprine and aminosalicylates: an in vivo study in patients with Crohn's disease. Aliment Pharmacol Ther 2002; 16: 79-85.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 79-85
    • Dewit, O.1    Vanheuverzwyn, R.2    Desager, J.P.3    Horsmans, Y.4
  • 28
    • 18444410760 scopus 로고    scopus 로고
    • Effects of aminosalicylates on thiopurine S-methyltransferase activity: An ex vivo study in patients with inflammatory bowel disease
    • Xin H, Fischer C, Schwab M, Klotz U. Effects of aminosalicylates on thiopurine S-methyltransferase activity: an ex vivo study in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2005; 21: 1105-9.
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 1105-1109
    • Xin, H.1    Fischer, C.2    Schwab, M.3    Klotz, U.4
  • 29
    • 0008690916 scopus 로고
    • Cortisone in ulcerative colitis: Final report on a therapeutic trial
    • Truelove SC, Witts LJ. Cortisone in ulcerative colitis: final report on a therapeutic trial. BMJ 1955; 4947: 1041-8.
    • (1955) BMJ , vol.4947 , pp. 1041-1048
    • Truelove, S.C.1    Witts, L.J.2
  • 30
    • 0028228699 scopus 로고
    • Thiopurine methyltransferase activity in a French population: HPLC assay conditions and effects of drugs and inhibitors
    • Jacques-Aigrain E, Bessa E, Medard Y, Mircheva Y, Vilmer E. Thiopurine methyltransferase activity in a French population: HPLC assay conditions and effects of drugs and inhibitors. Br J Clin Pharmacol 1994; 38: 1-8.
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 1-8
    • Jacques-Aigrain, E.1    Bessa, E.2    Medard, Y.3    Mircheva, Y.4    Vilmer, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.