메뉴 건너뛰기




Volumn 40, Issue 2, 2005, Pages 149-154

13C-methionine breath test detects distinct hepatic mitochondrial dysfunction in HIV-infected patients with normal serum lactate

Author keywords

13C methionine breath test; HIV; Mitochondrial toxicity

Indexed keywords

CARBON 13; DIDANOSINE; DNA DIRECTED DNA POLYMERASE GAMMA; LACTIC ACID; METHIONINE; METHIONINE C 13; MITOCHONDRIAL DNA; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; UNCLASSIFIED DRUG; CARBON;

EID: 25844467679     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.qai.0000179465.48571.d5     Document Type: Article
Times cited : (26)

References (29)
  • 1
    • 0034699898 scopus 로고    scopus 로고
    • Adverse effects of antiretroviral therapy
    • Carr A, Cooper DA. Adverse effects of antiretroviral therapy. Lancet. 2000;356:1423-1430.
    • (2000) Lancet , vol.356 , pp. 1423-1430
    • Carr, A.1    Cooper, D.A.2
  • 2
    • 0029154249 scopus 로고
    • Hepatomegaly and steatosis in HIV-infected patients receiving nucleoside analog antiretroviral therapy
    • Fortgang IS, Belitsos PC, Chaisson RE, et al. Hepatomegaly and steatosis in HIV-infected patients receiving nucleoside analog antiretroviral therapy. Am J Gastroenterol. 1995;90:1433-1436.
    • (1995) Am J Gastroenterol , vol.90 , pp. 1433-1436
    • Fortgang, I.S.1    Belitsos, P.C.2    Chaisson, R.E.3
  • 3
    • 0032897185 scopus 로고    scopus 로고
    • Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion
    • Chariot P, Drogou I, de Lacroix-Szmania I, et al. Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion. J Hepatol. 1999;30:156-160.
    • (1999) J Hepatol , vol.30 , pp. 156-160
    • Chariot, P.1    Drogou, I.2    De Lacroix-Szmania, I.3
  • 4
    • 0025274663 scopus 로고
    • Mitochondrial myopathy caused by long-term zidovudine therapy
    • Dalakas MC, Illa I, Pezeshkpour GH, et al. Mitochondrial myopathy caused by long-term zidovudine therapy. N Engl J Med. 1990;322:1098-1105.
    • (1990) N Engl J Med , vol.322 , pp. 1098-1105
    • Dalakas, M.C.1    Illa, I.2    Pezeshkpour, G.H.3
  • 5
    • 0034493575 scopus 로고    scopus 로고
    • Symptomatic hyperlactataemia: An emerging complication of antiretroviral therapy
    • Gerard Y, Maulin L, Yazdanpanah Y, et al. Symptomatic hyperlactataemia: an emerging complication of antiretroviral therapy. AIDS. 2000;14:2723-2730.
    • (2000) AIDS , vol.14 , pp. 2723-2730
    • Gerard, Y.1    Maulin, L.2    Yazdanpanah, Y.3
  • 6
    • 0033604038 scopus 로고    scopus 로고
    • Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
    • Brinkman K, Smeitink JA, Romijn JA, et al. Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy. Lancet. 1999;354:1112-1115.
    • (1999) Lancet , vol.354 , pp. 1112-1115
    • Brinkman, K.1    Smeitink, J.A.2    Romijn, J.A.3
  • 7
    • 0032710215 scopus 로고    scopus 로고
    • Nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity as an etiology for lipodystrophy
    • Kakuda TN, Brundage RC, Anderson PL, et al. Nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity as an etiology for lipodystrophy. AIDS. 1999;13:2311-2312.
    • (1999) AIDS , vol.13 , pp. 2311-2312
    • Kakuda, T.N.1    Brundage, R.C.2    Anderson, P.L.3
  • 8
    • 0028148674 scopus 로고
    • Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis
    • Martin JL, Brown CE, Matthews-Davis N, et al. Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis. Antimicrob Agents Chemother. 1994;38:2743-2749.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 2743-2749
    • Martin, J.L.1    Brown, C.E.2    Matthews-Davis, N.3
  • 9
    • 0035968164 scopus 로고    scopus 로고
    • Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma
    • Lim SE, Copeland WC. Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma. J Biol Chem. 2001;276:23616-23623.
    • (2001) J Biol Chem , vol.276 , pp. 23616-23623
    • Lim, S.E.1    Copeland, W.C.2
  • 10
    • 0037076029 scopus 로고    scopus 로고
    • Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients
    • Cote HC, Brumme ZL, Craib KJ, et al. Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients. N Engl J Med. 2002;346:811-820.
    • (2002) N Engl J Med , vol.346 , pp. 811-820
    • Cote, H.C.1    Brumme, Z.L.2    Craib, K.J.3
  • 11
    • 10744222741 scopus 로고    scopus 로고
    • Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine
    • Walker UA, Bauerle J, Laguno M, et al. Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine. Hepatology. 2004;39:311-317.
    • (2004) Hepatology , vol.39 , pp. 311-317
    • Walker, U.A.1    Bauerle, J.2    Laguno, M.3
  • 12
    • 0042410593 scopus 로고    scopus 로고
    • Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients
    • Pace CS, Martin AM, Hammond EL, et al. Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients. Antivir Ther. 2003;8:323-331.
    • (2003) Antivir Ther , vol.8 , pp. 323-331
    • Pace, C.S.1    Martin, A.M.2    Hammond, E.L.3
  • 13
    • 0033935975 scopus 로고    scopus 로고
    • Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity
    • Kakuda TN. Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity. Clin Ther. 2000;22: 685-708.
    • (2000) Clin Ther , vol.22 , pp. 685-708
    • Kakuda, T.N.1
  • 14
    • 0037045058 scopus 로고    scopus 로고
    • Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors
    • Walker UA, Setzer B, Venhoff N. Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors. AIDS. 2002;16:2165-2173.
    • (2002) AIDS , vol.16 , pp. 2165-2173
    • Walker, U.A.1    Setzer, B.2    Venhoff, N.3
  • 15
    • 25844466513 scopus 로고    scopus 로고
    • note
    • Deleted in proof.
  • 16
    • 25844490984 scopus 로고    scopus 로고
    • note
    • Deleted in proof.
  • 17
    • 25844465710 scopus 로고    scopus 로고
    • note
    • Deleted in proof.
  • 19
    • 0023732986 scopus 로고
    • Methionine metabolism in mammals. The methionine-sparing effect of cystine
    • Finkelstein JD, Martin JJ, Harris BJ. Methionine metabolism in mammals. The methionine-sparing effect of cystine. J Biol Chem. 1988;263:11750-11754.
    • (1988) J Biol Chem , vol.263 , pp. 11750-11754
    • Finkelstein, J.D.1    Martin, J.J.2    Harris, B.J.3
  • 21
    • 0037274675 scopus 로고    scopus 로고
    • 13C- methionine breath test in patients with macrovesicular steatosis and patients with cirrhosis
    • 13C-methionine breath test in patients with macrovesicular steatosis and patients with cirrhosis. Med Sci Monit. 2003;9:CR6-CR11.
    • (2003) Med Sci Monit , vol.9
    • Spahr, L.1    Negro, F.2    Leandro, G.3
  • 22
    • 1542723589 scopus 로고    scopus 로고
    • 13C-methionine breath test detects liver mitochondrial impairment in HIV-infected patients with antiretroviral drug-related hyperlactatemia
    • 13C-methionine breath test detects liver mitochondrial impairment in HIV-infected patients with antiretroviral drug-related hyperlactatemia. J Acquir Immune Defic Syndr. 2004; 35:429-432.
    • (2004) J Acquir Immune Defic Syndr , vol.35 , pp. 429-432
    • Milazzo, L.1    Riva, A.2    Sangaletti, O.3
  • 24
    • 20844453407 scopus 로고    scopus 로고
    • Mitochondrial effects of HIV infection on the peripheral blood mononuclear cells of HIV-infected patients who were never treated with antiretrovirals
    • Miro O, Lopez S, Martinez E, et al. Mitochondrial effects of HIV infection on the peripheral blood mononuclear cells of HIV-infected patients who were never treated with antiretrovirals. Clin Infect Dis. 2004;39:710-716.
    • (2004) Clin Infect Dis , vol.39 , pp. 710-716
    • Miro, O.1    Lopez, S.2    Martinez, E.3
  • 25
    • 19644363034 scopus 로고    scopus 로고
    • Extensive investigations of mitochondrial DNA genome in treated HIV-infected subjects: Beyond mitochondrial DNA depletion
    • McComsey G, Bai RK, Maa JF, et al. Extensive investigations of mitochondrial DNA genome in treated HIV-infected subjects: beyond mitochondrial DNA depletion. J Acquir Immune Defic Syndr. 2005;39: 181-188.
    • (2005) J Acquir Immune Defic Syndr , vol.39 , pp. 181-188
    • McComsey, G.1    Bai, R.K.2    Maa, J.F.3
  • 26
    • 0034598337 scopus 로고    scopus 로고
    • The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore
    • Jacotot E, Ravagnan L, Loeffler M, et al. The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J Exp Med. 2000;191:33-46.
    • (2000) J Exp Med , vol.191 , pp. 33-46
    • Jacotot, E.1    Ravagnan, L.2    Loeffler, M.3
  • 27
    • 0034517170 scopus 로고    scopus 로고
    • Mitochondrial control of cell death induced by HIV-1-encoded proteins
    • Ferri KF, Jacotot E, Blanco J, et al. Mitochondrial control of cell death induced by HIV-1-encoded proteins. Ann NY Acad Sci. 2000;926:149-164.
    • (2000) Ann NY Acad Sci , vol.926 , pp. 149-164
    • Ferri, K.F.1    Jacotot, E.2    Blanco, J.3
  • 28
    • 0034899305 scopus 로고    scopus 로고
    • Binding of human immunodeficiency virus type 1 gp120 to CXCR4 induces mitochondrial transmembrane depolarization and cytochrome C-mediated apoptosis independently of Fas signaling
    • Roggero R, Robert-Hebmann V, Harrington S, et al. Binding of human immunodeficiency virus type 1 gp120 to CXCR4 induces mitochondrial transmembrane depolarization and cytochrome C-mediated apoptosis independently of Fas signaling. J Virol. 2001;75:7637-7650.
    • (2001) J Virol , vol.75 , pp. 7637-7650
    • Roggero, R.1    Robert-Hebmann, V.2    Harrington, S.3
  • 29
    • 0037020155 scopus 로고    scopus 로고
    • HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells
    • Muthumani K, Hwang DS, Desai BM, et al. HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells. J Biol Chem. 2002;277:37820-37831.
    • (2002) J Biol Chem , vol.277 , pp. 37820-37831
    • Muthumani, K.1    Hwang, D.S.2    Desai, B.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.