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Volumn 76, Issue 3, 2005, Pages 241-250

The multidisciplinary rectal cancer treatment: Main convergences, controversial aspects and investigational areas which support the need for an European Consensus

(16)  Valentini, Vincenzo a,n   Glimelius, Bengt b   Minsky, Bruce D c   Van Cutsem, Eric d   Bartelink, Hanry e   Beets Tan, Regina G H f   Gerard, Jean Pierre g   Kosmidis, Paris h   Pahlman, Lars b   Picciocchi, Aurelio a   Quirke, Phil i   Tepper, Joel j   Tonato, Maurizio k   Van De Velde, Cornelius J l   Cellini, Numa a   Latini, Paolo m  


Author keywords

Chemotherapy; Combined modality treatment; Postoperative radiotherapy; Preoperative radiotherapy; Rectal cancer; Staging; Treatment outcome

Indexed keywords

FLUOROURACIL; FOLINIC ACID; OXALIPLATIN;

EID: 25844442570     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2005.07.001     Document Type: Conference Paper
Times cited : (46)

References (64)
  • 1
    • 0025710611 scopus 로고
    • Adjuvant therapy for patients with colon and rectal cancer
    • NIH consensus conference
    • NIH consensus conference Adjuvant therapy for patients with colon and rectal cancer JAMA 264 11 1990 1444 1450
    • (1990) JAMA , vol.264 , Issue.11 , pp. 1444-1450
  • 2
    • 0032914568 scopus 로고    scopus 로고
    • The accuracy of transrectal ultrasound in predicting the pathological stage of low-lying rectal cancer after preoperative chemoradiation therapy
    • B. Barbaro, A. Schulsinger, and V. Valentini The accuracy of transrectal ultrasound in predicting the pathological stage of low-lying rectal cancer after preoperative chemoradiation therapy Int J Radiat Oncol Biol Phys 43 1999 1043 1047
    • (1999) Int J Radiat Oncol Biol Phys , vol.43 , pp. 1043-1047
    • Barbaro, B.1    Schulsinger, A.2    Valentini, V.3
  • 3
    • 0033896171 scopus 로고    scopus 로고
    • Usefulness of endorectal ultrasound after preoperative radiotherapy in rectal cancer
    • M. Gavioli, A. Bagni, and I. Piccagli Usefulness of endorectal ultrasound after preoperative radiotherapy in rectal cancer Dis Colon Rectum 43 2000 1075 1083
    • (2000) Dis Colon Rectum , vol.43 , pp. 1075-1083
    • Gavioli, M.1    Bagni, A.2    Piccagli, I.3
  • 4
    • 0042355688 scopus 로고    scopus 로고
    • Rectal cancer: How accurate can imaging predict the T stage and the circumferential resection margin?
    • R.G.H. Beets-Tan, and G.L. Beets Rectal cancer: how accurate can imaging predict the T stage and the circumferential resection margin? Int J Colorec Dis 18 2003 385 391
    • (2003) Int J Colorec Dis , vol.18 , pp. 385-391
    • Beets-Tan, R.G.H.1    Beets, G.L.2
  • 5
    • 0035901059 scopus 로고    scopus 로고
    • Accuracy of magnetic resonance imaging in prediction of tumor-free resection margin in rectal cancer surgery
    • R.G.H. Beets-Tan, G.L. Beets, and R.F.A. Vliegen Accuracy of magnetic resonance imaging in prediction of tumor-free resection margin in rectal cancer surgery Lancet 357 2001 497 504
    • (2001) Lancet , vol.357 , pp. 497-504
    • Beets-Tan, R.G.H.1    Beets, G.L.2    Vliegen, R.F.A.3
  • 6
    • 0037406971 scopus 로고    scopus 로고
    • Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison
    • G. Brown, C.J. Richards, and M.W. Bourne Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison Radiology 227 2003 371 377
    • (2003) Radiology , vol.227 , pp. 371-377
    • Brown, G.1    Richards, C.J.2    Bourne, M.W.3
  • 7
    • 0037183247 scopus 로고    scopus 로고
    • Diffusion MRI for prediction of response of rectal cancer to chemoradiation
    • A. Dzik-Jurask, C. Domenig, and M. George Diffusion MRI for prediction of response of rectal cancer to chemoradiation Lancet 360 2002 307 308
    • (2002) Lancet , vol.360 , pp. 307-308
    • Dzik-Jurask, A.1    Domenig, C.2    George, M.3
  • 8
    • 0005009256 scopus 로고    scopus 로고
    • Prospective evaluation of the prognostic significance of FDG-PET assessment of rectal cancer response to preoperative chemoradiation
    • J.G. Guillem, H.G. Moore, and T. Akhurst Prospective evaluation of the prognostic significance of FDG-PET assessment of rectal cancer response to preoperative chemoradiation Proc ASCO 21 2002 145a
    • (2002) Proc ASCO , vol.21
    • Guillem, J.G.1    Moore, H.G.2    Akhurst, T.3
  • 9
    • 0026632370 scopus 로고
    • Combined modality therapy of rectal cancer: Decreased acute toxicity with the pre-operative approach
    • B.D. Minsky, A.M. Cohen, and W.E. Enker Combined modality therapy of rectal cancer: Decreased acute toxicity with the pre-operative approach J Clin Oncol 10 1992 1218 1224
    • (1992) J Clin Oncol , vol.10 , pp. 1218-1224
    • Minsky, B.D.1    Cohen, A.M.2    Enker, W.E.3
  • 10
    • 0034706001 scopus 로고    scopus 로고
    • Preoperative radiotherapy for resectable rectal cancer: A meta-analysis
    • C. Camma, M. Giunta, F. Fiorica, L. Pagliaro, A. Craxi, and M. Cottone Preoperative radiotherapy for resectable rectal cancer: A meta-analysis JAMA 284 2000 1008 1015
    • (2000) JAMA , vol.284 , pp. 1008-1015
    • Camma, C.1    Giunta, M.2    Fiorica, F.3    Pagliaro, L.4    Craxi, A.5    Cottone, M.6
  • 11
    • 0035922657 scopus 로고    scopus 로고
    • Adjuvant therapy for rectal cancer: A systematic overview of 8507 patients from 22 randomised trials
    • Colorectal Cancer Collaborative Group
    • Colorectal Cancer Collaborative Group Adjuvant therapy for rectal cancer: a systematic overview of 8507 patients from 22 randomised trials Lancet 358 2001 1291 1304
    • (2001) Lancet , vol.358 , pp. 1291-1304
  • 13
    • 0141525385 scopus 로고    scopus 로고
    • Cavallin-ståhl e a systematic overview of radiation therapy effects in rectal cancer
    • B. Glimelius, H. Grönberg, J. Järhult, and A. Wallgren Cavallin-ståhl E A systematic overview of radiation therapy effects in rectal cancer Acta Oncol 42 2003 476 492
    • (2003) Acta Oncol , vol.42 , pp. 476-492
    • Glimelius, B.1    Grönberg, H.2    Järhult, J.3    Wallgren, A.4
  • 14
    • 1842377447 scopus 로고    scopus 로고
    • Improved survival with preoperative radiotherapy in resectable rectal cancer
    • Swedish Rectal Cancer Trial
    • Swedish Rectal Cancer Trial Improved survival with preoperative radiotherapy in resectable rectal cancer N Engl J Med 336 1997 980 987
    • (1997) N Engl J Med , vol.336 , pp. 980-987
  • 15
    • 0035975394 scopus 로고    scopus 로고
    • Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer
    • E. Kapiteijn, C.A.M. Marijnen, and I.D. Nagtegaal Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer New Engl J Med 345 2001 638 646
    • (2001) New Engl J Med , vol.345 , pp. 638-646
    • Kapiteijn, E.1    Marijnen, C.A.M.2    Nagtegaal, I.D.3
  • 16
    • 0003322126 scopus 로고    scopus 로고
    • Preoperative radiotherapy and TME-surgery for rectal cancer: Detailed analysis in relation to quality control in a randomized trial
    • C.J.H. van de Velde Preoperative radiotherapy and TME-surgery for rectal cancer: detailed analysis in relation to quality control in a randomized trial Proc ASCO 21 2002 127a
    • (2002) Proc ASCO , vol.21
    • Van De Velde, C.J.H.1
  • 17
    • 0036467652 scopus 로고    scopus 로고
    • Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: Report of a multicenter randomized trial
    • C.A.M. Marijnen, E. Kapiteijn, and C.J.H. van de Velde Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: Report of a multicenter randomized trial J Clin Oncol 20 2002 817 825
    • (2002) J Clin Oncol , vol.20 , pp. 817-825
    • Marijnen, C.A.M.1    Kapiteijn, E.2    Van De Velde, C.J.H.3
  • 18
    • 0142092687 scopus 로고    scopus 로고
    • Neoadjuvant radiation and chemotherapy in rectal cancer does not increase postoperative complications
    • G. Valero, J.A. Lujan, and Q. Hernandez Neoadjuvant radiation and chemotherapy in rectal cancer does not increase postoperative complications Int J Colorec Dis 18 2003 495 499
    • (2003) Int J Colorec Dis , vol.18 , pp. 495-499
    • Valero, G.1    Lujan, J.A.2    Hernandez, Q.3
  • 19
    • 18244396398 scopus 로고    scopus 로고
    • Complete response to neoadjuvant chemoradiation for rectal cancer does not influence survival
    • M.W. Onaitis, R.B. Noone, and R. Fields Complete response to neoadjuvant chemoradiation for rectal cancer does not influence survival Ann Surg Oncol 8 2001 801 806
    • (2001) Ann Surg Oncol , vol.8 , pp. 801-806
    • Onaitis, M.W.1    Noone, R.B.2    Fields, R.3
  • 20
    • 0035045195 scopus 로고    scopus 로고
    • Improved overall survival among responders to preoperative chemoradiation for locally advanced rectal cancer
    • N.A. Janjan, C. Crane, and B.W. Feig Improved overall survival among responders to preoperative chemoradiation for locally advanced rectal cancer Am J Clin Oncol 24 2001 107 112
    • (2001) Am J Clin Oncol , vol.24 , pp. 107-112
    • Janjan, N.A.1    Crane, C.2    Feig, B.W.3
  • 21
    • 0036161040 scopus 로고    scopus 로고
    • Assessing the predictive value of clinical complete response to neoadjuvant therapy for rectal cancer: An analysis of 488 patients
    • S.P. Hiotis, S.M. Weber, and A.M. Cohen Assessing the predictive value of clinical complete response to neoadjuvant therapy for rectal cancer: an analysis of 488 patients J Am Coll Surg 194 2002 131 136
    • (2002) J Am Coll Surg , vol.194 , pp. 131-136
    • Hiotis, S.P.1    Weber, S.M.2    Cohen, A.M.3
  • 22
    • 0036295040 scopus 로고    scopus 로고
    • Long-term prognostic significance of extent of rectal cancer response to preoperative radiation and chemotherapy
    • L. Ruo, S. Tickoo, and D.S. Klimstra Long-term prognostic significance of extent of rectal cancer response to preoperative radiation and chemotherapy Ann Surg 236 2002 75 81
    • (2002) Ann Surg , vol.236 , pp. 75-81
    • Ruo, L.1    Tickoo, S.2    Klimstra, D.S.3
  • 23
    • 0036644223 scopus 로고    scopus 로고
    • Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? a long term analysis of 165 patients
    • V. Valentini, C. Coco, and A. Picciocchi Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? A long term analysis of 165 patients Int J Radiat Oncol Biol Phys 53 2002 664 674
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 664-674
    • Valentini, V.1    Coco, C.2    Picciocchi, A.3
  • 24
    • 0037339012 scopus 로고    scopus 로고
    • A pathologic complete response to preoperative chemoradiation is associated with lower local recurrence and improved survival in rectal cancer patients treated by mesorectal excision
    • J. Garcia-Aguilar, E. Hernandez de Anda, and P. Sirivongs A pathologic complete response to preoperative chemoradiation is associated with lower local recurrence and improved survival in rectal cancer patients treated by mesorectal excision Dis Colon Rectum 46 2003 298 304
    • (2003) Dis Colon Rectum , vol.46 , pp. 298-304
    • Garcia-Aguilar, J.1    Hernandez De Anda, E.2    Sirivongs, P.3
  • 25
    • 0034333264 scopus 로고    scopus 로고
    • Prognostic significance of postchemoradiation stage following preoperative chemotherapy and radiation for advanced/recurrent rectal cancers
    • M. Mohiuddin, M. Hayne, and W.F. Regine Prognostic significance of postchemoradiation stage following preoperative chemotherapy and radiation for advanced/recurrent rectal cancers Int J Radiat Oncol Biol Phys 48 2000 1075 1080
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 1075-1080
    • Mohiuddin, M.1    Hayne, M.2    Regine, W.F.3
  • 26
    • 0028985756 scopus 로고
    • The Stockholm I trial of preoperative short term radiotherapy in operable rectal carcinoma
    • B. Cedermark, H. Johansson, L.E. Rutqvist, and N. Wilking The Stockholm I trial of preoperative short term radiotherapy in operable rectal carcinoma Cancer 75 1995 2269 2275
    • (1995) Cancer , vol.75 , pp. 2269-2275
    • Cedermark, B.1    Johansson, H.2    Rutqvist, L.E.3    Wilking, N.4
  • 27
    • 22144462216 scopus 로고    scopus 로고
    • Preoperative radiotherapy (Preop RT) in rectal canacer: Effect and timing of additional chemotherapy (CT) 5 year results of the EORTC 22921 trial
    • J.F. Bosset, G. Calais, and L. Mineur Preoperative radiotherapy (Preop RT) in rectal canacer: effect and timing of additional chemotherapy (CT) 5 year results of the EORTC 22921 trial Proc ASCO 2005 3505
    • (2005) Proc ASCO , pp. 3505
    • Bosset, J.F.1    Calais, G.2    Mineur, L.3
  • 28
    • 22144488561 scopus 로고    scopus 로고
    • Preoperative (preop) radiotherapy (RT) +5FU/folinic acid (FA) in T3-4 rectal cancers: Results of the FFCD 9203 randomized trial
    • J. Gerard, F. Bonnetain, and O. Conroy Preoperative (preop) radiotherapy (RT) +5FU/folinic acid (FA) in T3-4 rectal cancers: results of the FFCD 9203 randomized trial Proc. ASCO 2005 3504
    • (2005) Proc. ASCO , pp. 3504
    • Gerard, J.1    Bonnetain, F.2    Conroy, O.3
  • 29
    • 3242716904 scopus 로고    scopus 로고
    • Sphincter preservation following preoperative radiotherapy for rectal cancer: Report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy
    • K. Bujko, M.P. Nowacki, and A. Nasierowska-Guttmejer Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy Radiother Oncol 72 2004 15 24
    • (2004) Radiother Oncol , vol.72 , pp. 15-24
    • Bujko, K.1    Nowacki, M.P.2    Nasierowska-Guttmejer, A.3
  • 30
    • 6044226542 scopus 로고    scopus 로고
    • Preoperative versus postoperative chemoradiotherapy for rectal cancer
    • R. Sauer, H. Becker, W. Hohenberger, and C. Rodel Preoperative versus postoperative chemoradiotherapy for rectal cancer N Engl J Med 351 2004 1731 1740
    • (2004) N Engl J Med , vol.351 , pp. 1731-1740
    • Sauer, R.1    Becker, H.2    Hohenberger, W.3    Rodel, C.4
  • 31
    • 0030951055 scopus 로고    scopus 로고
    • Short-term preoperative radiotherapy results in down-staging of rectal cancer: A study of 1316 patients
    • W. Graf, M. Dahlberg, and M.M. Osman Short-term preoperative radiotherapy results in down-staging of rectal cancer: a study of 1316 patients Radiother Oncol 43 1997 133 137
    • (1997) Radiother Oncol , vol.43 , pp. 133-137
    • Graf, W.1    Dahlberg, M.2    Osman, M.M.3
  • 32
    • 0035300761 scopus 로고    scopus 로고
    • No downstaging after short-term preoperative radiotherapy in rectal cancer patients
    • C.A.M. Marijnen, I.D. Nagtegaal, and E.K. Kranenbarg No downstaging after short-term preoperative radiotherapy in rectal cancer patients J Clin Oncol 19 2001 1976 1984
    • (2001) J Clin Oncol , vol.19 , pp. 1976-1984
    • Marijnen, C.A.M.1    Nagtegaal, I.D.2    Kranenbarg, E.K.3
  • 33
    • 0036203964 scopus 로고    scopus 로고
    • Restorative and nonrestorative surgery for low rectal cancer after high dose radiation. Long term oncologic and functional results
    • P. Rouanet, B. Saint Aubert, and C. Lemanski Restorative and nonrestorative surgery for low rectal cancer after high dose radiation. Long term oncologic and functional results Dis Colon Rectum 45 2002 305 315
    • (2002) Dis Colon Rectum , vol.45 , pp. 305-315
    • Rouanet, P.1    Saint Aubert, B.2    Lemanski, C.3
  • 34
    • 0031671241 scopus 로고    scopus 로고
    • Sphincter preservation with preoperative radiation therapy and coloanal anastomosis: Long term follow-up
    • R. Wagman, B.D. Minsky, and A.M. Cohen Sphincter preservation with preoperative radiation therapy and coloanal anastomosis: long term follow-up Int J Radiat Oncol Biol Phys 42 1998 51 57
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 51-57
    • Wagman, R.1    Minsky, B.D.2    Cohen, A.M.3
  • 35
    • 0035479071 scopus 로고    scopus 로고
    • Ten years of preoperative chemoradiation for extraperitoneal T3 rectal cancer: Acute toxicity, tumor response, and sphincter preservation in three consecutive studies
    • V. Valentini, C. Coco, and N. Cellini Ten years of preoperative chemoradiation for extraperitoneal T3 rectal cancer: acute toxicity, tumor response, and sphincter preservation in three consecutive studies Int J Radiat Oncol Biol Phys. 51 2001 371 383
    • (2001) Int J Radiat Oncol Biol Phys. , vol.51 , pp. 371-383
    • Valentini, V.1    Coco, C.2    Cellini, N.3
  • 36
    • 0041912759 scopus 로고    scopus 로고
    • Phase I/II trial of capecitibine, oxaliplatin, and radiation for rectal cancer
    • C. Rodel, G.G. Grabenbauer, and T. Papadopoulos Phase I/II trial of capecitibine, oxaliplatin, and radiation for rectal cancer J Clin Oncol 21 2003 3098 3104
    • (2003) J Clin Oncol , vol.21 , pp. 3098-3104
    • Rodel, C.1    Grabenbauer, G.G.2    Papadopoulos, T.3
  • 37
    • 0037445116 scopus 로고    scopus 로고
    • Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: The Lyon R0-04 phase II trial
    • J.P. Gerard, O. Chapet, and C. Nemoz Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: the Lyon R0-04 phase II trial J Clin Oncol 21 2003 1119 1124
    • (2003) J Clin Oncol , vol.21 , pp. 1119-1124
    • Gerard, J.P.1    Chapet, O.2    Nemoz, C.3
  • 38
    • 0012722437 scopus 로고    scopus 로고
    • A phase I-II study of weekly oxaliplatin (OXA) 5-fluorouracil (FU) continuous infusion (CI) and preoperative radiotherapy (RT) in locally advanced rectal cancer (LARC)
    • C. Aschele, M.L. Friso, and S. Pucciarelli A phase I-II study of weekly oxaliplatin (OXA) 5-fluorouracil (FU) continuous infusion (CI) and preoperative radiotherapy (RT) in locally advanced rectal cancer (LARC) Proc ASCO 21 2002 132a
    • (2002) Proc ASCO , vol.21
    • Aschele, C.1    Friso, M.L.2    Pucciarelli, S.3
  • 39
    • 0037827276 scopus 로고    scopus 로고
    • Preoperative hyperfractionated accelerated radiotherapy (HART) and concomitant CPT-11 in locally advanced rectal carcinoma: A phase I study
    • V. Voelter, R. Stupp, and M. Matter Preoperative hyperfractionated accelerated radiotherapy (HART) and concomitant CPT-11 in locally advanced rectal carcinoma: a phase I study Int J Radiat Oncol Biol Phys 56 2003 1288 1294
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 1288-1294
    • Voelter, V.1    Stupp, R.2    Matter, M.3
  • 40
    • 3042755429 scopus 로고    scopus 로고
    • Phase I/II study of irinotecan (CPT-11), 5-fluorouracil and concurrent radiotherapy for the treatment of T3-T4 locally advanced inoperable rectal cancer
    • E.L. Levine, S. Gollins, and S. Susnerwala Phase I/II study of irinotecan (CPT-11), 5-fluorouracil and concurrent radiotherapy for the treatment of T3-T4 locally advanced inoperable rectal cancer Proc ASCO 22 2003 345
    • (2003) Proc ASCO , vol.22 , pp. 345
    • Levine, E.L.1    Gollins, S.2    Susnerwala, S.3
  • 41
    • 0037827307 scopus 로고    scopus 로고
    • Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operable rectal cancer
    • J. Souglakos, N. Androulakis, and D. Mavroudis Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operable rectal cancer Int J Radiat Oncol Biol Phys 56 2003 1284 1287
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 1284-1287
    • Souglakos, J.1    Androulakis, N.2    Mavroudis, D.3
  • 42
    • 0036787579 scopus 로고    scopus 로고
    • Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer
    • J. Dunst, T. Reese, and T. Sutter Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer J Clin Oncol 20 2002 3983 3991
    • (2002) J Clin Oncol , vol.20 , pp. 3983-3991
    • Dunst, J.1    Reese, T.2    Sutter, T.3
  • 43
    • 0032812135 scopus 로고    scopus 로고
    • Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: The Lyon R90-01 randomized trial
    • Y. Francois, C.J. Nemoz, and J. Baulieux Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: The Lyon R90-01 randomized trial J Clin Oncol 17 1999 2396 2402
    • (1999) J Clin Oncol , vol.17 , pp. 2396-2402
    • Francois, Y.1    Nemoz, C.J.2    Baulieux, J.3
  • 44
    • 2942750356 scopus 로고    scopus 로고
    • Improved sphincter preservation in low rectal cancer with high-dose preoperative radiotherapy: The lyon r96-02 randomized trial
    • J.P. Gerard, O. Chapet, and C. Nemoz Improved sphincter preservation in low rectal cancer with high-dose preoperative radiotherapy: the lyon r96-02 randomized trial J Clin Oncol 22 2004 2404 2409
    • (2004) J Clin Oncol , vol.22 , pp. 2404-2409
    • Gerard, J.P.1    Chapet, O.2    Nemoz, C.3
  • 45
    • 0026071185 scopus 로고
    • Effective surgical adjuvant therapy for high-risk rectal carcinoma
    • J.E. Krook, C.G. Moertel, and L.L. Gunderson Effective surgical adjuvant therapy for high-risk rectal carcinoma N Engl J Med 324 1991 709 715
    • (1991) N Engl J Med , vol.324 , pp. 709-715
    • Krook, J.E.1    Moertel, C.G.2    Gunderson, L.L.3
  • 46
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery
    • M.J. O'Connell, J.A. Martenson, and H.S. Wieand Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery N Engl J Med 331 1994 502 507
    • (1994) N Engl J Med , vol.331 , pp. 502-507
    • O'Connell, M.J.1    Martenson, J.A.2    Wieand, H.S.3
  • 47
    • 0036534143 scopus 로고    scopus 로고
    • Adjuvant therapy in rectal cancer: Analysis of stage, sex, and local control - Final report of Intergroup 0114
    • J.E. Tepper, M.J. O'Connell, and D. Niedzwiecki Adjuvant therapy in rectal cancer: analysis of stage, sex, and local control - final report of Intergroup 0114 J Clin Oncol 20 2002 1744 1750
    • (2002) J Clin Oncol , vol.20 , pp. 1744-1750
    • Tepper, J.E.1    O'Connell, M.J.2    Niedzwiecki, D.3
  • 48
    • 3042760073 scopus 로고    scopus 로고
    • Intergroup 0144 - Phase III trial of 5-FU based chemotherapy regimens plus radiotherapy (XRT) in postoperative adjuvant rectal cancer. Bolus 5-FU vs. prolonged venous infusion (PVI) before and after XRT + PVI vs. bolus 5-FU + leucovorin (LV) + Levamisole (LEV) before and after XRT + bolus 5-FU + LV
    • S.R. Smalley, J. Benedetti, and S. Williamson Intergroup 0144 - phase III trial of 5-FU based chemotherapy regimens plus radiotherapy (XRT) in postoperative adjuvant rectal cancer. Bolus 5-FU vs. prolonged venous infusion (PVI) before and after XRT + PVI vs. bolus 5-FU + leucovorin (LV) + Levamisole (LEV) before and after XRT + bolus 5-FU + LV Proc ASCO 22 2003 251
    • (2003) Proc ASCO , vol.22 , pp. 251
    • Smalley, S.R.1    Benedetti, J.2    Williamson, S.3
  • 49
    • 0036533844 scopus 로고    scopus 로고
    • Randomized trial of postoperative adjuvant therapy in stage II and III rectal cancer to define the optimal sequence of chemotherapy and radiotherapy: A preliminary report
    • J.H.L. Lee, J.H. Lee, and J.H. Ahn Randomized trial of postoperative adjuvant therapy in stage II and III rectal cancer to define the optimal sequence of chemotherapy and radiotherapy: A preliminary report J Clin Oncol 20 2002 1751 1758
    • (2002) J Clin Oncol , vol.20 , pp. 1751-1758
    • Lee, J.H.L.1    Lee, J.H.2    Ahn, J.H.3
  • 50
    • 0033007459 scopus 로고    scopus 로고
    • Prognostic factors in stage T3N0 rectal cancer. Do all patients require post-operative pelvic irradiation and chemotherapy?
    • C.G. Willett, K. Badizadegan, and M. Ancukiewicz Prognostic factors in stage T3N0 rectal cancer. Do all patients require post-operative pelvic irradiation and chemotherapy? Dis Colon Rectum 42 1999 167 173
    • (1999) Dis Colon Rectum , vol.42 , pp. 167-173
    • Willett, C.G.1    Badizadegan, K.2    Ancukiewicz, M.3
  • 51
    • 0033220455 scopus 로고    scopus 로고
    • T3N0 rectal cancer: Results following sharp mesorectal excision and no adjuvant therapy
    • N.B. Merchant, J.G. Guillem, and P.B. Paty T3N0 rectal cancer: results following sharp mesorectal excision and no adjuvant therapy J Gastrointest Surg 3 1999 642 647
    • (1999) J Gastrointest Surg , vol.3 , pp. 642-647
    • Merchant, N.B.1    Guillem, J.G.2    Paty, P.B.3
  • 52
    • 3042796221 scopus 로고    scopus 로고
    • A new TNM staging strategy for node-positive (stage III) rectal cancer: An analysis of 5998 patients
    • F.L. Green, A.K. Stewart, and H.J. Norton A new TNM staging strategy for node-positive (stage III) rectal cancer: an analysis of 5998 patients Proc ASCO 22 2003 251
    • (2003) Proc ASCO , vol.22 , pp. 251
    • Green, F.L.1    Stewart, A.K.2    Norton, H.J.3
  • 53
    • 0027986558 scopus 로고
    • The long term effect of adjuvant postoperative chemoradiotherapy for rectal cancer on bowel function
    • C.F. Kollmorgen, A.P. Meagher, and J.H. Pemberton The long term effect of adjuvant postoperative chemoradiotherapy for rectal cancer on bowel function Ann Surg 220 1994 676 682
    • (1994) Ann Surg , vol.220 , pp. 676-682
    • Kollmorgen, C.F.1    Meagher, A.P.2    Pemberton, J.H.3
  • 54
    • 3042825347 scopus 로고    scopus 로고
    • Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: A pooled analysis
    • L.L. Gunderson, D.J. Sargent, and J.E. Tepper Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis J Clin Oncol 22 2004 1785 1796
    • (2004) J Clin Oncol , vol.22 , pp. 1785-1796
    • Gunderson, L.L.1    Sargent, D.J.2    Tepper, J.E.3
  • 55
    • 0037531121 scopus 로고    scopus 로고
    • Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: Interim results of a phase III trial
    • M.A. Rothenberg, A.M. Oza, and R.H. Bigelow Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim results of a phase III trial J Clin Oncol 21 2003 2059 2069
    • (2003) J Clin Oncol , vol.21 , pp. 2059-2069
    • Rothenberg, M.A.1    Oza, A.M.2    Bigelow, R.H.3
  • 56
    • 0042213493 scopus 로고    scopus 로고
    • N9741: Oxaliplatin (Oxal) or CPT-11+5-fluorouracil (5-FU)/Leucovorin (LV) or oxal + CPT-11 in advanced colorectal cancer (CRC). Updated efficacy and quality of life
    • R.M. Goldberg, R.F. Morton, and D.J. Sargent N9741: oxaliplatin (Oxal) or CPT-11+5-fluorouracil (5-FU)/Leucovorin (LV) or oxal + CPT-11 in advanced colorectal cancer (CRC). Updated efficacy and quality of life Proc ASCO 22 2003 252
    • (2003) Proc ASCO , vol.22 , pp. 252
    • Goldberg, R.M.1    Morton, R.F.2    Sargent, D.J.3
  • 57
    • 0034727063 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
    • L.B. Saltz, J.V. Cox, and C. Blanke Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer N Engl J Med 343 2000 905 914
    • (2000) N Engl J Med , vol.343 , pp. 905-914
    • Saltz, L.B.1    Cox, J.V.2    Blanke, C.3
  • 58
    • 0037862765 scopus 로고    scopus 로고
    • Cetuximab (C225) alone or in combination with irinotecan (CPT-11) in patients with epidermal growth factor receptor (EGFR)-positive, irinotecan-refractory metastatic colorectal cancer (MCRC)
    • D. Cunningham, Y. Humblet, and S. Siena Cetuximab (C225) alone or in combination with irinotecan (CPT-11) in patients with epidermal growth factor receptor (EGFR)-positive, irinotecan-refractory metastatic colorectal cancer (MCRC) Proc ASCO 22 2003 252
    • (2003) Proc ASCO , vol.22 , pp. 252
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 59
    • 0037236085 scopus 로고    scopus 로고
    • Oxaliplatin plus raltitrexed in the treatment of patients with advanced colorectal cancer: A phase II study
    • A. Martoni, E. Mini, and C. Pinto Oxaliplatin plus raltitrexed in the treatment of patients with advanced colorectal cancer: a phase II study Anticancer Res 23 2003 687 691
    • (2003) Anticancer Res , vol.23 , pp. 687-691
    • Martoni, A.1    Mini, E.2    Pinto, C.3
  • 60
    • 0036667943 scopus 로고    scopus 로고
    • Raltitrexed plus oxaliplatin as a first-line chemotherapy in metastatic colorectal carcinoma: A multicentric phase II trial
    • B. Neri, L. Doni, and C. Fulignati Raltitrexed plus oxaliplatin as a first-line chemotherapy in metastatic colorectal carcinoma: a multicentric phase II trial Anticancer Drugs 13 2002 719 724
    • (2002) Anticancer Drugs , vol.13 , pp. 719-724
    • Neri, B.1    Doni, L.2    Fulignati, C.3
  • 61
    • 0035990835 scopus 로고    scopus 로고
    • Multicenter non-randomized phase II study of raltitrexed (Tomudex) and oxaliplatin in non-pretreated metastatic colorectal cancer patients
    • J.F. Seitz, J. Bennouna, and B. Paillot Multicenter non-randomized phase II study of raltitrexed (Tomudex) and oxaliplatin in non-pretreated metastatic colorectal cancer patients Ann Oncol 13 2002 1072 1079
    • (2002) Ann Oncol , vol.13 , pp. 1072-1079
    • Seitz, J.F.1    Bennouna, J.2    Paillot, B.3
  • 62
    • 11144354462 scopus 로고    scopus 로고
    • Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: Integrated efficacy data and novel analyses from two large, randomized, phase III trials
    • E. Van Cutsem, P.M. Hoff, and P. Harper Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomized, phase III trials Br J Cancer 90 2004 1190 1197
    • (2004) Br J Cancer , vol.90 , pp. 1190-1197
    • Van Cutsem, E.1    Hoff, P.M.2    Harper, P.3
  • 63
    • 0035985287 scopus 로고    scopus 로고
    • Raltitrexed plus oxaliplatin (TOMOX) as first-line chemotherapy for metastatic colorectal cancer. a phase II study of the Italian Group for the Study of Gastrointestinal Tract Carcinomas (GISCAD)
    • S. Cascinu, F. Graziano, and F. Ferrau Raltitrexed plus oxaliplatin (TOMOX) as first-line chemotherapy for metastatic colorectal cancer. A phase II study of the Italian Group for the Study of Gastrointestinal Tract Carcinomas (GISCAD) Ann Oncol 13 2002 716 720
    • (2002) Ann Oncol , vol.13 , pp. 716-720
    • Cascinu, S.1    Graziano, F.2    Ferrau, F.3
  • 64
    • 21344432989 scopus 로고    scopus 로고
    • Targeted drugs in metastatic colorectal cancer with special emphasis on guidelines for the use of bevacizumab and cetuximab: An Acta Oncologica expert report
    • P. Nygren, H. Sorbye, P. Österlund, and P. Pfeiffer Targeted drugs in metastatic colorectal cancer with special emphasis on guidelines for the use of bevacizumab and cetuximab: An Acta Oncologica expert report Acta Oncol 44 2005 203 217
    • (2005) Acta Oncol , vol.44 , pp. 203-217
    • Nygren, P.1    Sorbye, H.2    Österlund, P.3    Pfeiffer, P.4


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