An accumulation of glucosylceramide in the stratum corneum due to attenuated activity of beta-glucocerebrosidase is associated with the early phase of UVB-induced alteration in cutaneous barrier function

Archives of Dermatological Research

Volumn 297, Issue 1, 2005, Pages 18-25

  Takagi, Yutaka ^b   Nakagawa, Hidemi ^a   Yaginuma, Toshiaki ^b   Takema, Yoshinori ^b   Imokawa, Genji ^b  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Kao Biological Science Laboratories   (Japan)

Author keywords

Glucocerebrosidase; Glucosylceramide; Permeability barrier; Stratum corneum; UVB irradiation

Indexed keywords

BETA GLUCOCEREBROSIDASE; CERAMIDE; GLUCOSYLCERAMIDASE; GLUCOSYLCERAMIDE; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; EPIDERMIS; LIPID STORAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; SKIN FUNCTION; STRATUM CORNEUM; ULTRAVIOLET B RADIATION;

ANIMALS; EPIDERMIS; GLUCOSYLCERAMIDASE; GLUCOSYLCERAMIDES; MALE; MICE; MICE, INBRED HRS; RNA, MESSENGER; SKIN; SPHINGOLIPIDS; ULTRAVIOLET RAYS;

EID: 25644450313     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-005-0567-7     Document Type: Article

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