메뉴 건너뛰기




Volumn 25, Issue 2, 1998, Pages 73-77

Effect of an inhibitor of glucosylceramide synthesis on cultured human keratinocytes

Author keywords

Cell growth; Glucosylceramide; Keratinocytes

Indexed keywords

2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; CERAMIDE GLYCOSYLTRANSFERASE; CERAMIDE GLYCOSYLTRANSFERASE INHIBITOR; ENZYME INHIBITOR; GLUCOSYLCERAMIDE; UNCLASSIFIED DRUG;

EID: 0031944191     PISSN: 03852407     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1346-8138.1998.tb02353.x     Document Type: Article
Times cited : (14)

References (22)
  • 1
    • 0024795059 scopus 로고
    • Sphimgomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation
    • Okazaki T, Bell RM, Hannun VA: Sphimgomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation, J Biol Chem, 264: 19076-19080, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 19076-19080
    • Okazaki, T.1    Bell, R.M.2    Hannun, V.A.3
  • 2
    • 0026270031 scopus 로고
    • Lipid modulators of epidermal proliferation and differentiation
    • Holleran WM: Lipid modulators of epidermal proliferation and differentiation, Adv Lipid Res, 24: 119-139, 1991.
    • (1991) Adv Lipid Res , vol.24 , pp. 119-139
    • Holleran, W.M.1
  • 3
    • 0028303749 scopus 로고
    • Keratinocyte differentiation is induced by cell-permeant ceramides and its proliferation is promoted by sphingosine
    • Wakita H, Tokura Y, Yagi H, Nishimura K, Furukawa F, Takigawa M: Keratinocyte differentiation is induced by cell-permeant ceramides and its proliferation is promoted by sphingosine, Arch Dermatol Res, 286: 350-354, 1994.
    • (1994) Arch Dermatol Res , vol.286 , pp. 350-354
    • Wakita, H.1    Tokura, Y.2    Yagi, H.3    Nishimura, K.4    Furukawa, F.5    Takigawa, M.6
  • 4
    • 0024541436 scopus 로고
    • Functions of sphingolipids and sphingolipid breakdown products in cellular regulation
    • Hannun YA, Bell RM: Functions of sphingolipids and sphingolipid breakdown products in cellular regulation, Science, 243: 500-507, 1989.
    • (1989) Science , vol.243 , pp. 500-507
    • Hannun, Y.A.1    Bell, R.M.2
  • 5
    • 0029927759 scopus 로고    scopus 로고
    • Sphingolipids: Their role in intracellular signaling and renal growth
    • Shayman JA: Sphingolipids: Their role in intracellular signaling and renal growth, J Am Soc Nephrol, 7: 171-182, 1996.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 171-182
    • Shayman, J.A.1
  • 6
    • 0023258056 scopus 로고
    • Preparation of the active isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthase
    • Inokuchi J, Radin NS: Preparation of the active isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthase, J Lipid Res, 28: 565-571, 1987.
    • (1987) J Lipid Res , vol.28 , pp. 565-571
    • Inokuchi, J.1    Radin, N.S.2
  • 7
    • 0026528994 scopus 로고
    • Improved inhibitors of glucosyl; ceramide synthase
    • Abe A, Inokuchi J, Jimbo M, et al: Improved inhibitors of glucosyl; ceramide synthase, J Biochem, 111: 191-196, 1992.
    • (1992) J Biochem , vol.111 , pp. 191-196
    • Abe, A.1    Inokuchi, J.2    Jimbo, M.3
  • 8
    • 0028913218 scopus 로고
    • Structural and stereochemical studies of potent inhibitors of glucosyl ceramide synthase and tumor cell growth
    • Abe A, Radin NS, Shayman JA, et al: Structural and stereochemical studies of potent inhibitors of glucosyl ceramide synthase and tumor cell growth, J Lipid Res, 36: 611-621, 1995.
    • (1995) J Lipid Res , vol.36 , pp. 611-621
    • Abe, A.1    Radin, N.S.2    Shayman, J.A.3
  • 9
    • 0024993445 scopus 로고
    • Effect of an inhibitor of glucosylceraminde synthesis on cultured rabbit skin fibroblasts
    • Uemura K, Sugiyama E, Tamai C, Hara A, Taketomi T, Radin NS: Effect of an inhibitor of glucosylceraminde synthesis on cultured rabbit skin fibroblasts, J Biochem, 108: 525-530, 1990.
    • (1990) J Biochem , vol.108 , pp. 525-530
    • Uemura, K.1    Sugiyama, E.2    Tamai, C.3    Hara, A.4    Taketomi, T.5    Radin, N.S.6
  • 10
    • 0023501151 scopus 로고
    • Antitumor activity via inhibition of glycosphingolipid biosynthesis
    • Inokuchi J, Mason I, Radin NS: Antitumor activity via inhibition of glycosphingolipid biosynthesis, Cancer Lett, 38: 23-30, 1987.
    • (1987) Cancer Lett , vol.38 , pp. 23-30
    • Inokuchi, J.1    Mason, I.2    Radin, N.S.3
  • 11
    • 0030039399 scopus 로고    scopus 로고
    • Glucosylceramide synthase inhibitor, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol exhibits a novel decarnogenic activity against Shope carcinoma cells
    • Kyogashima M, Inoue M, Seto A, Inokuchi J: Glucosylceramide synthase inhibitor, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol exhibits a novel decarnogenic activity against Shope carcinoma cells, Cancer Lett, 101: 25-30, 1996.
    • (1996) Cancer Lett , vol.101 , pp. 25-30
    • Kyogashima, M.1    Inoue, M.2    Seto, A.3    Inokuchi, J.4
  • 12
    • 0024796873 scopus 로고
    • Effects of D-threo-PDMP, an inhibitor of glucosylceramide synthase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells
    • Inokuchi J, Momosaki K, Shimeno H, Nagamatsu A, Radin NS: Effects of D-threo-PDMP, an inhibitor of glucosylceramide synthase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells, J Cell Physiol, 141: 573-583, 1989.
    • (1989) J Cell Physiol , vol.141 , pp. 573-583
    • Inokuchi, J.1    Momosaki, K.2    Shimeno, H.3    Nagamatsu, A.4    Radin, N.S.5
  • 13
    • 0025027772 scopus 로고
    • Inhibition of experimental metastasis of murine Lewis lung carcinoma by an inhibitor of glucosylceramide synthase and its possible mechanism of action
    • Inokuchi J, Jimbo M, Momosaki K, Shimeno H, Nagamatsu A, Radin NS: Inhibition of experimental metastasis of murine Lewis lung carcinoma by an inhibitor of glucosylceramide synthase and its possible mechanism of action, Cancer Res, 50: 6731-6737, 1990.
    • (1990) Cancer Res , vol.50 , pp. 6731-6737
    • Inokuchi, J.1    Jimbo, M.2    Momosaki, K.3    Shimeno, H.4    Nagamatsu, A.5    Radin, N.S.6
  • 14
    • 0029811581 scopus 로고    scopus 로고
    • Induction of ceramide glucosyltransferase activity in culture human keratinocytes correlation with culture differentiation
    • Sando GN, Howard EJ, Madison KC: Induction of ceramide glucosyltransferase activity in culture human keratinocytes correlation with culture differentiation, J Biol Chem, 271: 22044-22051, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 22044-22051
    • Sando, G.N.1    Howard, E.J.2    Madison, K.C.3
  • 15
    • 0020513440 scopus 로고
    • Calcium regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum free serial culture
    • Boyce ST, Ham RG: Calcium regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum free serial culture, J Invest Dermatol, 81: 33s-40s, 1983.
    • (1983) J Invest Dermatol , vol.81
    • Boyce, S.T.1    Ham, R.G.2
  • 16
    • 0027487129 scopus 로고
    • Regulation of keratinocyte growth, differentiation, and vitamin D metabolism by analog of 1,25-dehydroxyvitamin D
    • Bikle DD, Gee E, Pillai S: Regulation of keratinocyte growth, differentiation, and vitamin D metabolism by analog of 1,25-dehydroxyvitamin D, J Invest Dermatol, 101: 713-718, 1993.
    • (1993) J Invest Dermatol , vol.101 , pp. 713-718
    • Bikle, D.D.1    Gee, E.2    Pillai, S.3
  • 17
    • 0016819768 scopus 로고
    • Lipid compositions of cells isolated from pig, human, and rat epidermis
    • Gray GM, Yardley HJ: Lipid compositions of cells isolated from pig, human, and rat epidermis, J Lipid Res, 16: 434-440, 1975.
    • (1975) J Lipid Res , vol.16 , pp. 434-440
    • Gray, G.M.1    Yardley, H.J.2
  • 18
    • 0020615145 scopus 로고
    • Human stratum corneum lipids: Characterization and regional variations
    • Lampe MA, Burlingame AL, Whitney J, et al: Human stratum corneum lipids: characterization and regional variations, J Lipid Res, 24: 120-130, 1983.
    • (1983) J Lipid Res , vol.24 , pp. 120-130
    • Lampe, M.A.1    Burlingame, A.L.2    Whitney, J.3
  • 19
    • 0020615146 scopus 로고
    • Human epidermal lipids: Characterization and modulations during differentiation
    • Lampe MA, Williams ML, Elias PM: Human epidermal lipids: characterization and modulations during differentiation, J Lipid Res, 24: 131-140, 1983.
    • (1983) J Lipid Res , vol.24 , pp. 131-140
    • Lampe, M.A.1    Williams, M.L.2    Elias, P.M.3
  • 20
    • 0027412708 scopus 로고
    • Structure determination of glycosphingolipids of cultured human keratinocytes
    • Hanaoka S, Takemoto T, Hamanaka Y, et al: Structure determination of glycosphingolipids of cultured human keratinocytes, Biochim Biophys Acta, 1167: 1-8, 1993.
    • (1993) Biochim Biophys Acta , vol.1167 , pp. 1-8
    • Hanaoka, S.1    Takemoto, T.2    Hamanaka, Y.3
  • 22
    • 0029010643 scopus 로고
    • Glucosylceramides stimulate murine epidermal hyperproliferation
    • Marsh NL, Elias PM, Holleran WM: Glucosylceramides stimulate murine epidermal hyperproliferation, J Clinic Invest, 95: 2903-2909, 1995.
    • (1995) J Clinic Invest , vol.95 , pp. 2903-2909
    • Marsh, N.L.1    Elias, P.M.2    Holleran, W.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.