Macrolides and lincomycin susceptibility of Mycoplasma hyorhinis and variable mutation of domain II and V in 23S ribosomal RNA

Journal of Veterinary Medical Science

Volumn 67, Issue 8, 2005, Pages 795-800

  Kobayashi, Hideki ^a   Nakajima, Hiromi ^a,b   Shimizu, Yuka ^a,c   Eguchi, Masashi ^a   Hata, Eiji ^a   Yamamoto, Koshi ^a,d  

^a NATIONAL INSTITUTE OF ANIMAL HEALTH   (Japan)

^b Nagano Prefectural Matsumoto Livestock Hygiene Service Center   (Japan)

^c Hyogo Prefectural Himeji Livestock Hygiene Service Center   (Japan)

^d El Laboratorio Regional de Patologia Animal de El Salto   (Mexico)

Author keywords

23S ribosomal RNA; Antimicrobial susceptibility; Macrolide resistance; Mycoplasma hyorhinis; Tylosin

Indexed keywords

ANTIINFECTIVE AGENT; LINCOMYCIN; MACROLIDE; PRIMER DNA; RNA 23S;

ANIMAL; ARTICLE; BASE PAIRING; COMPARATIVE STUDY; DNA SEQUENCE; DRUG EFFECT; GENETICS; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MOLECULAR GENETICS; MUTATION; MYCOPLASMA HYORHINIS; NUCLEOTIDE SEQUENCE; SPECIES DIFFERENCE; SWINE;

ANIMALS; ANTI-BACTERIAL AGENTS; BASE PAIRING; BASE SEQUENCE; DNA PRIMERS; LINCOMYCIN; MACROLIDES; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; MYCOPLASMA HYORHINIS; RNA, RIBOSOMAL, 23S; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY; SUS SCROFA;

ESCHERICHIA COLI; MYCOPLASMA HYORHINIS; SUIDAE; SUS SCROFA;

EID: 25644448170     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.67.795     Document Type: Article

References (24)

1. Aarestrup, F. M., Friis, N. F. and Szancer, J. 1998. Antimicrobial susceptibility of Mycoplasma hyorhinis in a liquid medium compared to a disc assay. Acta Vet. Scand. 39: 145-147.
2. Felmingham, D., Robbins, M. J., Sanghrajka, M., Leakey, A. and Ridgway, G. L. 1991. The in vitro activity of some 14-, 15-and 16-membered macrolides against Staphylococcus spp., Legionella spp., and Ureaplasma urealyticum. Drugs Exp. Clin. Res. 17: 91-99.
3. Friis, N. F. 1974. Mycoplasma suipneumoniae and Mycoplasma flocculare in comparative pathogenicity studies. Acta Vet. Scand. 15: 507-518.
4. Friis, N. F. and Feenstra, A. A. 1994. Mycoplasma hyorhinis in the etiology of serositis among piglets. Acta Vet. Scand. 35: 93-98.
5. Garza-Ramos G., Xiong, L., Zhong, P. and Mankin, A. 2001. Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA. J. Bacteriol. 183: 6898-6907.
6. Hannan, P. C. T., Windsor, G. D., DeJong, A., Schmeer, N. and Stegemann, M. 1997. Comparative susceptibilities of various animal pathogenic Mycoplasmas to fluoroquinolines. Antimicrob. Agents Chemother. 41: 2037-2040.
7. Jenkins, G. and Cundliffe, E. 1991. Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics. Gene 108: 55-62.
8. Kobayashi, H., Morozumi, T., Miyamoto, C., Shimizu, M., Yamada, S., Ohashi, S., Kubo, M., Kimura, K., Mitani, K., Ito, N. and Yamamoto, K. 1996. Mycoplasma hyorhinis infection levels in lungs of piglets with porcine reproductive and respiratory syndrome (PRRS). J. Vet. Med. Sci. 58: 109-113.
9. Kobayashi, H., Morozumi, T., Munthali, G., Mitani, K., Ito, N. and Yamamoto, K. 1996. Macrolide susceptibility of Mycoplasma hyorhinis isolated from piglets. Antimicrob. Agents Chemother. 40: 1030-1032.
10. Kojima, A. 2004. A national surveillance of antimicrobial susceptibility of zoonotic bacterial strains isolated from food-producing animals in Japan in 2001. Proc. Jpn. Pig. Vet. Soc. 44: 14-19 (in Japanese).
11. Kobayashi, H., Sonmez, N., Morozumi, T., Mitani, K., Ito, N., Shiono, H. and Yamamoto, K. 1996. In vitro susceptibility of Mycoplasma hyosynoviae and M. hyorhinis to antimicrobial agents. J. Vet. Med. Sci. 58: 1107-1111.
12. Lucier, T. S., Heitzman, K., Liu, S. K. and Hu, P. C. 1995. Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae. Antimicrob. Agents Chemother. 39: 2770-2773.
13. Morita, T., Fukuda, H., Awakura, T., Shimada, A., Uemura, T., Kazama, S. and Yagihashi, T. 1995. Demonstration of Mycoplasma hyorhinis as a possible primary pathogen for porcine otitis media. Vet. Pathol. 32: 107-111.
14. Ohara, K., Kanda, T., Ohmiya, K., Ebisu, T. and Kono, M. 1989. Purification and characterization of macrolide 29-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin. Antimicrob. Agents Chemother. 33: 1354-1357.
15. Ounissi, H. and Courvalin, P. 1985. Nucleotide sequence of the gene ereA encoding the erythromycin esterase in Escherichia coli. Gene 35: 271-278.
16. Pardo, D. and Rosset, R. 1977. Properties of ribosomes from erythromycin-resistant mutants of E. coli. Mol. Gen. Genet. 156: 267-271.
17. Pereyre, S., Guyot, C., Renaudin, H., Charron, A., Bebear, C. and Bebear, C. M. 2004. In vitro selection and characterization of resistance to macrolides and related antibiotics in Mycoplasma pneumoniae. Antimicrob. Agents Chemother. 48: 460-465.
18. Pereyre, S., Gonzalez, P., de Barbeyrac, B., Darnige, A., Renaudin, H., Charron, A., Raherison, S., Bebear, C. and Bebear, C. M. 2002. Mutation in 23S rRNA accounts for intrinsic resistance to macrolides in Mycoplasma hominis and Mycoplasma fermentans and for acquired resistance to macrolides in M. hominis. Antimicrob. Agents Chemother. 46: 3142-3150.
19. Shimizu, M., Yamada, S., Murakami, Y., Morozumi, T., Kobayashi, H., Mitani, K., Ito, N., Kubo, M., Kimura, K., Kobayashi, M., Yamamoto, K., Miura, Y., Yamamoto, T. and Watanabe, K. 1993. Isolation of porcine reproductive and respiratory syndrome (PRRS) virus from Heko-Heko disease of pigs. J. Vet. Med. Sci. 56: 389-391.
20. Ter Laak, E. A., Pijpers, A., Noordergraaf, J. H., Schoevers, E. C. and Verheijden, J. H. M. 1991. Comparison of methods for in vitro testing of susceptibility of porcine Mycoplasma species to antimicrobial agents. Antimicrob. Agents Chemother. 35: 228-233.
21. The Japanese Pig Veterinary Society. 2002. Proc. Jpn. Pig. Vet. Soc. 41: 21-34 (in Japanese).
22. Weisblum, B. 1995. Erythromycin resistance by ribosome modification. Antimicrob. Agents Chemother. 39: 577-585.
23. Wittmann, H. G., Stoffler, G., Aprion, D., Rosen, L., Tanaka, K., Tamaki, M., Tanaka, R., Dekio, S., Otaka, E. and Osawa, S. 1973. Biochemical and genetic studies on two different types of erythromycin resistance of Escherichia coli with altered ribosomal proteins. Mol. Gen. Genet. 127: 175-189.
24. Wu, C. C., Shryock, T. R., Lin, T. L., Faderan, M. and Veenhuizen, M. F. 2000. Antimicrobial susceptibility of Mycoplasma hyorhinis. Vet. Microbiol. 76: 25-30.