Analysis of T-cell receptor gene rearrangement for predicting clinical outcome in patients with cutaneous T-cell lymphoma: A comparison of Southern blot and polymerase chain reaction methods

Archives of Dermatology

Volumn 141, Issue 9, 2005, Pages 1107-1113

  Juarez, Thaddeus ^a   Isenhath, Scott N ^d   Polissar, Nayak L ^c   Sabath, Daniel E ^d   Wood, Brent ^d   Hanke, Deena ^d   Haycox, Claire L ^d   Wood, Gary S ^b   Olerud, John E ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c Mountain Whisper Light Statistical Consulting   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; T LYMPHOCYTE RECEPTOR;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER STAGING; CAPILLARY ELECTROPHORESIS; COHORT ANALYSIS; CUTANEOUS T CELL LYMPHOMA; DENATURING GRADIENT GEL ELECTROPHORESIS; ERYTHRODERMA; FEMALE; GENE REARRANGEMENT; HAZARD ASSESSMENT; HISTOLOGY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KAPLAN MEIER METHOD; LYMPH NODE; LYMPH NODE BIOPSY; LYMPHADENOPATHY; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OUTCOMES RESEARCH; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; PROBABILITY; PROGNOSIS; REGRESSION ANALYSIS; RISK ASSESSMENT; SKIN TUMOR; SOUTHERN BLOTTING; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; T LYMPHOCYTE; TIME SERIES ANALYSIS; TREATMENT OUTCOME;

AGED; BLOTTING, SOUTHERN; CLONE CELLS; ELECTROPHORESIS, CAPILLARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; FOLLOW-UP STUDIES; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; GENE REARRANGEMENT, GAMMA-CHAIN T-CELL ANTIGEN RECEPTOR; HUMANS; LYMPH NODES; LYMPHOMA, T-CELL, CUTANEOUS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROGNOSIS; SKIN NEOPLASMS; SURVIVAL RATE; T-LYMPHOCYTES;

EID: 25444454597     PISSN: 0003987X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archderm.141.9.1107     Document Type: Article

References (36)

1. Olerud JE, Kulin PA, Chew DE, et al. Cutaneous T-cell lymphoma. Arch Dermatol. 1992;128:501-507.
2. Willemze R, Kerl H, Sterry W, et al. EORTC classification for primary cutaneous lymphomas. Blood. 1997;90:354-371.
3. Kim YH, Liu HL, Mraz-Gernhard S, Varghese A, Hoppe RT. Long-term outcome of 525 patients with mycosis fungoides and Sézary syndrome: clinical prognostic factors and risk for disease progression. Arch Dermatol. 2003;139:857-866.
4. Foss FM, Sausville EA. Prognosis and staging of cutaneous T-cell lymphoma. Hematol Oncol Clin North Am. 1995;9:1011-1019.
5. Kim YH, Chow S, Varghese A, Hoppe RT. Clinical characteristics and long-term outcome of patients with generalized patch and/or plaque (T2) mycosis fungoides. Arch Dermatol. 1999;135:26-32.
6. Abel EA, Wood GS, Hoppe RT. Mycosis fungoides. CA Cancer J Clin. 1993;43:93-115.
7. Sausville EA, Eddy JL, Makuch RW, et al. Histopathologic staging at initial diagnosis of mycosis fungoides and the Sézary syndrome: definition of three distinctive prognostic groups. Ann Intern Med. 1988;109:372-382.
8. Guitart J, Camisa C, Ehrlich M, Bergfeld WF. Long-term implications of T-cell receptor gene rearrangement analysis by Southern blot in patients with cutaneous T-cell lymphoma. J Am Acad Dermatol. 2003;48:775-779.
9. Kern DE, Kidd PG, Moe R, Hanke D, Olerud JE. Analysis of T-cell receptor gene rearrangement in lymph nodes of patients with mycosis fungoides: prognostic implications. Arch Dermatol. 1998;134:158-164.
10. Delfau-Larue MH, Dalac S, Lepage E, et al. Prognostic significance of a polymerase chain reaction-detectable dominant T-lymphocyte clone in cutaneous lesions of patients with mycosis fungoides. Blood. 1998;92:3376-3380.
11. Jones D, Duvic M. The current state and future of clonality studies in mycosis fungoides. J Invest Dermatol. 2003;121:ix-x.
12. Vega F, Luthra R, Medeiros LJ, et al. Clonal heterogeneity in mycosis fungoides and its relationship to clinical course. Blood. 2002;100:3369-3373.
13. Wood GS, Haeffner A, Dummer R, Crooks CF. Molecular biology techniques for the diagnosis of cutaneous T-cell lymphoma. Dermatol Clin. 1994;12:231-241.
14. Wood GS, Uluer AZ. Polymerase chain reaction/denaturing gradient gel electrophoresis (PCR-DGGE). Am J Dermatopathol. 1999;21:547-551.
15. Lessin SR, Rook AH, Rovera G. Molecular diagnosis of cutaneous T-cell lymphoma. J Invest Dermatol. 1991;96:299-302.
16. Bakels V, van Oostveen JW, Preesman AH, Meijer CJ, Willemze R. Differentiation between actinic reticuloid and cutaneous T cell lymphoma by T cell receptor gamma gene rearrangement analysis and immunophenotyping. J Clin Pathol. 1998;51:154-158.
17. Bunn PA Jr, Lamberg SI. Report of the Committee on Staging and Classification of Cutaneous T-Cell Lymphomas. Cancer Treat Rep. 1979;63:725-728.
18. Sausville EA, Worsham GF, Matthews MJ, et al. Histologic assessment of lymph nodes in mycosis fungoides/Sézary syndrome (cutaneous T-cell lymphoma). Hum Pathol. 1985;16:1098-1109.
19. Wood GS, Tung RM, Haeffner AC, et al. Detection of clonal T-cell receptor gamma gene rearrangements in early mycosis fungoides/Sézary syndrome by polymerase chain reaction and denaturing gradient gel electrophoresis (PCR-DGGE). J Invest Dermatol. 1994;103:34-41.
20. Sprouse JT, Werling R, Hanke D, et al. T-cell clonality determination using polymerase chain reaction (PCR) amplification of the T-cell receptor gamma-chain gene and capillary electrophoresis of fluorescently labeled PCR products. Am J Clin Pathol. 2000;113:838-850.
21. Vonderheid EC, Bernengo MG, Burg G, et al. Update on erythrodermic cutaneous T-cell lymphoma. J Am Acad Dermatol. 2002;46:95-106.
22. Dereure O, Balavoine M, Salles MT, et al. Correlations between clinical, histologic, blood, and skin polymerase chain reaction outcome in patients treated for mycosis fungoides. J Invest Dermatol. 2003;121:614-617.
23. Southern EM. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975;98:503-517.
24. Kamat D, Laszewski MJ, Kemp JD, et al. The diagnostic utility of immunophenotyping and immunogenotyping in the pathologic evaluation of lymphoid proliferations. Mod Pathol. 1990;3:105-112.
25. Bachelez H, Bioul L, Flageul B, et al. Detection of clonal T-cell receptor gamma gene rearrangements with the use of the polymerase chain reaction in cutaneous lesions of mycosis fungoides and Sézary syndrome. Arch Dermatol. 1995;131:1027-1031.
26. Curco N, Servitje O, Llucia M, et al. Genotypic analysis of cutaneous T-cell lymphoma: a comparative study of Southern blot analysis with polymerase chain reaction amplification of the T-cell receptor-gamma gene. Br J Dermatol. 1997;137:673-679.
27. Sklar J. Polymerase chain reaction. J Clin Oncol. 1991;9:1521-1524.
28. Delfau-Larue MH, Laroche L, Wechsler J, et al. Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma. Blood. 2000;96:2987-2992.
29. Muche JMLA, Heim J, Friedrich M, Audring H, Sterry W. Demonstration of frequent occurrence of clonal T cells in the peripheral blood but not in the skin of patients with small plaque parapsoriasis. Blood. 1999;94:1409-1417.
30. Schwab R, Szabo P, Manavalan JS, et al. Expanded CD4+ and CD8+ T cell clones in elderly humans. J Immunol. 1997;158:4493-4499.
31. Posnett DN Sr, Kabak S, Russo C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy." J Exp Med. 1994;179:609-618.
32. Zackheim HS, Amin S, Kashani-Sabet M, McMillan A. Prognosis in cutaneous T-cell lymphoma by skin stage: long-term survival in 489 patients. J Am Acad Dermatol. 1999;40:418-425.
33. Guitart J, Kaul K. A new polymerase chain reaction-based method for the detection of T-cell clonality in patients with possible cutaneous T-cell lymphoma. Arch Dermatol. 1999;135:158-162.
34. Gordon KB, Guitart J, Kuzel T, et al. Pseudo-mycosis fungoides in a patient taking clonazepam and fluoxetine. J Am Acad Dermatol. 1996;34:304-306.
35. Weiss LM, Wood GS, Trela M, Warnke RA, Sklar J. Clonal T-cell populations in lymphomatoid papulosis: evidence of a lymphoproliferative origin for a clinically benign disease. N Engl J Med. 1986;315:475-479.
36. Weiss LM, Wood GS, Ellisen LW, et al. Clonal T-cell populations in pityriasis lichenoides et varioliformis acuta (Mucha-Habermann disease).Am J Pathol. 1987;126:417-421.