Correlations between clinical, histologic, blood, and skin polymerase chain reaction outcome in patients treated for Mycosis Fungoides

Journal of Investigative Dermatology

Volumn 121, Issue 3, 2003, Pages 614-617

  Dereure, Olivier ^a,b   Balavoine, Muriel ^a   Salles, Marie Thérèse ^a   Candon Kerlau, Sophie ^a   Clot, Jacques ^a   Guilhou, Jean Jacques ^a   Eliaou, Jean François ^a  

^a MONTPELLIER UNIVERSITY HOSPITAL   (France)

^b HÔPITAL SAINT ELOI   (France)

Author keywords

Mycosis Fungoides; Post treatment outcome; TCR gene rearrangement

Indexed keywords

CARMUSTINE; METHOTREXATE; PSORALEN; RETINOID; T LYMPHOCYTE RECEPTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DOMINANT GENE; DOMINANT GENE REARRANGEMENT; FEMALE; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; MALE; MYCOSIS FUNGOIDES; PHOTOTHERAPY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SKIN DEFECT; T LYMPHOCYTE RECEPTOR GENE; TREATMENT OUTCOME; ULTRAVIOLET A RADIATION;

EID: 0042528278     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2003.12402.x     Document Type: Article

References (17)

1. Andrews EE Woolford A, Jones RR, Whittaker S: A peripheral blood T cell clone is a prognostic marker in mycosis fungoides. J Invest Dermatol 116:484-485, 2001
2. Bachelez H, Bioul L, Flageul B, et al: Detection of clonal T-cell receptor gamma gene rearrangements with the use of the polymerase chain reaction in cutaneous lesions of mycosis fungoides and Sézary syndrome. Arch Dermatol 131:1027-1031, 1995
3. Bakels V, van Oostveen JW, Gordijn RL, Walboomers JM, Meijer CJ, Willemze R: Frequency and prognostic significance of clonal T-cell receptor beta-gene rearrangements in the peripheral blood of patients with mycosis fungoides. Arch Dermatol 128:1602-1607, 1992
4. Beylot-Barry M, Sibaud V, Thiebaut R, et al: Evidence that an identical T cell clone in skin and peripheral blood lymphocytes is an independent prognostic factor in primary cutaneous T cell lymphomas. J Invest Dermatol 117:920-926, 2001
5. Curco N, Servitje O, Llucia M, et al: Genotypic analysis of cutaneous T-cell lymphoma: A comparative study of Southern blot analysis with polymerase chain reaction amplification of the T-cell receptor-gamma chain. Br J Dermatol 137:673-679, 1997
6. Delfau-Larue MH, Dalac S, Lepage E, Petrella T, Wechsler J, Farcet JP, Bagot M: Prognostic significance of a polymerase chain reaction-detectable dominant T-lymphocyte clone in cutaneous lesions of patients with mycosis fungoides. Blood 92:3376-3380, 1998a
7. Delfau-Larue MH, Petrella T, Lahet C, et al: Value of clonality studies of cutaneous T lymphocytes in the diagnosis and follow-up of patients with mycosis fungoides. J Pathol 184:183-190, 1998b
8. Delfau-Larue MH, Laroche L, Wechsler J, et al: Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma. Blood 96:2987-2992, 2000
9. Dommann SN, Dommann-Scherrer CC, Dours-Zimmermann MT, Zimmermann DR, Kural-Serbes B, Burg G: Clonal disease in extracutaneous compartments in cutaneous T-cell lymphomas. A comparative study between cutaneous T-cell lymphomas and pseudo lymphomas. Arch Dermatol Res 288:163-167, 1996
10. Fraser-Andrews EA, Woolford AJ, Russell-Jones R, Seed PT, Whittaker SJ: Detection of a peripheral blood T cell clone is an independent prognostic marker in mycosis fungoides. J Invest Dermatol 114:117-121, 2000
11. Muche JM, Lukowsky A, Asadullah K, Gellrich S, Sterry W: Demonstration of frequent occurrence of clonal T cells in the peripheral blood of patients with primary cutaneous T-cell lymphoma. Blood 90:1636-1642, 1997
12. Scarisbrick JJ, Whittaker S, Evans AV, Fraser-Andrews EA, Child FJ, Dean A, Russell-Jones R: Prognostic significance of tumor burden in the blood of patients with erythrodermic primary cutaneous T-cell lymphoma. Blood 97:624-630, 2001
13. Veelken H, Wood GS, Sklar J: Molecular staging of cutaneous T-cell lymphoma: Evidence for systemic involvement in early disease. J Invest Dermatol 104:889-894, 1995
14. Vega F, Luthra R, Medeiros LJ, Dunmire V, Lee SJ, Duvic M, Jones D: Clonal heterogeneity in mycosis fungoides and its relationship to clinical course. Blood 100:3369-3373, 2002
15. Weiss LM, Hu E, Wood GS, Moulds C, Cleary ML, Warnke R, Sklar J: Clonal rearrangements of T-cell receptor genes in mycosis fungoides and dermatopathic lymphadenopathy. N Engl Med 313:539-544, 1985
16. Weiss LM, Wood GS, Hu E, Abel EA, Hoppe RT, Sklar J: Detection of clonal T-cell receptor gene rearrangements in the peripheral blood of patients with mycosis fungoides/Sézary syndrome. J Invest Dermatol 92:601-604, 1989
17. Wood GS, Tung RM, Haeffner AC, et al: Detection of clonal T-cell receptor gamma gene rearrangements in early mycosis fungoides/Sézary syndrome by polymerase chain reaction and denaturing gradient gel electrophoresis (PCR/DGGE). J Invest Dermatol 103:34-41, 1994