Effects of methyl-β-cyclodextrin-mediated cholesterol depletion in porcine sperm compared to somatic cells

Molecular Reproduction and Development

Volumn 72, Issue 3, 2005, Pages 386-395

  Van Gestel, R A ^a   Helms, J B ^a   Brouwers, J F H M ^a   Gadella, B M ^a,b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Cyclodextrin; GM 1 staining; Membrane damage; Merocyanin; Sperm capacitation

Indexed keywords

CHOLERA TOXIN B SUBUNIT; CHOLESTEROL; GANGLIOSIDE GM1; MEROCYANINE; METHYL BETA CYCLODEXTRIN; PHOSPHOLIPID;

ACROSOME; ANIMAL CELL; ARTICLE; CELL STRAIN; CELL STRUCTURE; CELL VIABILITY; CHOLESTEROL DEPLETION; CYTOTOXICITY; DEPLETION; HUMAN; HUMAN CELL; IMMOBILIZATION; MALE; MEMBRANE DAMAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SOMATIC CELL; SPERMATOZOON; SPERMATOZOON CAPACITATION; SPERMATOZOON MOTILITY; SPERMICIDICITY; STAINING; SWINE;

ANIMALS; BETA-CYCLODEXTRINS; CELL MEMBRANE; CELLS, CULTURED; CHOLERA TOXIN; CHOLESTEROL; DOGS; FERTILIZATION IN VITRO; FLOW CYTOMETRY; FLUORESCENCE; MALE; PHOSPHOLIPIDS; PYRIMIDINONES; SPERM CAPACITATION; SUS SCROFA;

SUIDAE;

EID: 25444440315     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.20351     Document Type: Article

References (38)

1. Barenholz Y. 2004. Sphingomyelin and cholesterol: From membrane biophysics and rafts to potential medical applications. Subcell Biochem 37:167-215.
2. Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Canad J Biochem Physiol 37:911-917.
3. Brener E, Rubinstein S, Cohen G, Shternall K, Rivlin J, Breitbart H. 2003. Remodeling of the actin cytoskeleton during mammalian sperm capacitation and acrosome reaction. Biol Reprod 68:837-845.
4. Brouwers JF, Gadella BM, van Golde LM, Tielens AG. 1998. Quantitative analysis of phosphatidylcholine molecular species using HPLC and light scattering detection. J Lipid Res 39:344-353.
5. Chiu PC, Chung MK, Tsang HY, Koistinen R, Koistinen H, Seppala M, Lee KF, Yeung WS. 2005. Glycodelin-S in human seminal plasma reduces cholesterol effux and inhibits capacitation of spermatozoa. J Biol Chem 280:25580-25589.
6. Choi YH, Toyoda Y. 1998. Cyclodextrin removes cholesterol from mouse sperm and induces capacitation in a protein-free medium. Biol Reprod 59:1328-1333.
7. Davis BK, Byrne R, Hungund B. 1979. Studies on the mechanism of capacitation. II. Evidence for lipid transfer between plasma membrane of rat sperm and serum albumin during capacitation in vitro. Biochim Biophys Acta 558:257-266.
8. Davis BK, Byrne R, Bedigian K 1980. Studies on the mechanism of capacitation: Albumin-mediated changes in plasma membrane lipids during in vitro incubation of rat sperm cells. Proc Natl Acad Sci USA 77:1546-1550.
9. Droge JH, Janssen LH, Wilting J. 1982. A comparative study of some physico-chemical properties of human serum albumin samples from different sources-I. Some physico-chemical properties of isoionic human serum albumin solutions. Biochem Pharmacol 31:3775-3779.
10. Fainaru M, Schaeffer Z, Deckelbaum R. 1981. Isolation and characterization of lipid-protein complexes present in commercial albumin preparations. Prep Biochem 11:273-290.
11. Flesch FM, Voorhout WF, Colenbrander B, van Golde LM, Gadella BM. 1998. Use of lectins to characterize plasma membrane preparations from boar spermatozoa: A novel technique for monitoring membrane purity and quantity. Biol Reprod 59:1530-1539.
12. Flesch FM, Brouwers JF, Nievelstein PF, Verkleij AJ, van Golde LM, Colenbrander B, Gadella BM. 2001. Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane. J Cell Sci 114:3543-3555.
13. Furimsky A, Vuong N, Xu H, Kumarathasan P, Xu M, Weerachatyanukul W, Bou Khalil M, Kates M, Tanphaichitr N. 2005. Percoll gradient-centrifuged capacitated mouse sperm have increased fertilizing ability and higher contents of sulfogalactosylglycerolipid and docosahexaenoic acid-containing phosphatidylcholine compared to washed capacitated mouse sperm. Biol Reprod 72:574-583.
14. Gadella BM, Harrison RA. 2000. The capacitating agent bicarbonate induces protein kinase A-dependent changes in phospholipid transbilayer behavior in the sperm plasma membrane. Development 127:2407-2420.
15. Gadella BM, Colenbrander B, Lopes-Cardozo M. 1991. Arylsulfatases are present in seminal plasma of several domestic mammals. Biol Reprod 45:381-386.
16. Go KJ, Wolf DP. 1985. Albumin-mediated changes in sperm sterol content during capacitation. Biol Reprod 32:145-153.
17. Harder T, Scheiffele P, Verkade P, Simons K. 1998. Lipid domain structure of the plasma membrane revealed by patching of membrane components. J Cell Biol 141:929-942.
18. Harrison RA. 1996. Capacitation mechanisms, and the role of capacitation as seen in eutherian mammals. Reprod Fertil Dev 8:581-594.
19. Hegazy E, Lopez del Pino V, Schwenk M. 1983. Isolated intestinal mucosa cells of high viability from guinea pig. Eur J Cell Biol 30:132-136.
20. Iborra A, Companyo M, Martinez P, Morros A. 2000. Cholesterol efflux promotes acrosome reaction in goat spermatozoa. Biol Reprod 62:378-383.
21. Ilangumaran S, Hoessli DC. 1998. Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane. Biochem J 335:433-440.
22. Janes PW, Ley SC, Magee AI. 1999. Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor. J Cell Biol 147:447-461.
23. Kilsdonk EP, Yancey PG, Stoudt GW, Bangerter FW, Johnson WJ, Phillips MC, Rothblat GH. 1995. Cellular cholesterol efflux mediated by cyclodextrins. J Biol Chem 270:17250-17256.
24. Langlais J, Kan FW, Granger L, Raymond L, Bleau G, Roberts KD. 1988. Identification of sterol acceptors that stimulate cholesterol efflux from human spermatozoa during in vitro capacitation. Gamete Res 20:185-201.
25. Lopes CH, Mazzini MN, Tortorella H, Konrath RA, Brandelli A. 1998. Isolation, partial characterization and biological activity of mannosyl glycopeptides from seminal plasma. Glycoconj J 15:477-481.
26. Martinez P, Morros A. 1996. Membrane lipid dynamics during human sperm capacitation. Front Biosci 1:d103-d117.
27. Osheroff JE, Visconti PE, Valenzuela JP, Travis AJ, Alvarez J, Kopf GS. 1999. Regulation of human sperm capacitation by a cholesterol efflux-stimulated signal transduction pathway leading to protein kinase A-mediated up-regulation of protein tyrosine phosphorylation. Mol Hum Reprod 5:1017-1026.
28. Parinaud J, Vieitez G, Vieu C, Collet X, Perret B. 2000. Enhancement of zona binding using 2-hydroxypropyl-beta-cyclodextrin. Hum Reprod 15:1117-1120.
29. Pommer AC, Rutllant J, Meyers SA. 2003. Phosphorylation of protein tyrosine residues in fresh and cryopreserved stallion spermatozoa under capacitating conditions. Biol Reprod 68:1208-1214.
30. Ravnik SE, Albers JJ, Muller CH. 1993. A novel view of albumin-supported sperm capacitation: Role of lipid transfer protein-I. Fertil Steril 59:629-638.
31. Scheiffele P, Roth MG, Simons K. 1997. Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain. EMBO J 16:5501-5508.
32. Shadan S, James PS, Howes EA, Jones R. 2004. Cholesterol efflux alters lipid raft stability and distribution during capacitation of boar spermatozoa. Biol Reprod 71:253-265.
33. Sugkraroek P, Kates M, Leader A, Tanphaichitr N. 1991. Levels of cholesterol and phospholipids in freshly ejaculated sperm and Percoll-gradient-pelletted sperm from fertile and unexplained infertile men. Fertil Steril 55:820-827.
34. Visconti PE, Galantino-Homer H, Ning X, Moore GD, Valenzuela JP, Jorgez CJ, Alvarez JG, Kopf GS. 1999a. Cholesterol efflux-mediated signal transduction in mammalian sperm. Beta-cyclodextrins initiate transmembrane signaling leading to an increase in protein tyrosine phosphorylation and capacitation. J Biol Chem 274:3235-3242.
35. Visconti PE, Ning X, Fornes MW, Alvarez JG, Stein P, Connors SA, Kopf GS. 1999b. Cholesterol efflux-mediated signal transduction in mammalian sperm: Cholesterol release signals an increase in protein tyrosine phosphorylation during mouse sperm capacitation. Dev Biol 214:429-443.
36. Yanagimachi R. 1994. Mammalian fertilization. In: Knobil E, Neill JD, editors. The physiology of reproduction. New York: Raven Press, Ltd. pp 189-317.
37. Yancey PG, Rodrigueza WV, Kilsdonk EP, Stoudt GW, Johnson WJ, Phillips MC, Rothblat GH. 1996. Cellular cholesterol efflux mediated by cyclodextrins. Demonstration Of kinetic pools and mechanism of efflux. J Biol Chem 271:16026-16034.
38. Zarintash RJ, Cross NL. 1996. Unesterified cholesterol content of human sperm regulates the response of the acrosome to the agonist, progesterone. Biol Reprod 55:19-24.