Comparative analysis of B- and T-cell epitopes of Mycobacterium leprae and Mycobacterium tuberculosis culture filtrate protein 10

Infection and Immunity

Volumn 72, Issue 6, 2004, Pages 3161-3170

  Spencer, John S ^a   Kim, Hee Jin ^a   Marques, Angela M ^a   Gonzalez Juarerro, Mercedes ^a   Lima, Monica C B S ^b   Vissa, Varalakshmi D ^a   Truman, Richard W ^c   Gennaro, Maria Laura ^d   Cho, Sang Nae ^e   Cole, Stewart T ^f   Brennan, Patrick J ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c LOUISIANA STATE UNIVERSITY   (United States)

^d PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^e Yonsei University College of Medicine   (South Korea)

^f INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CULTURE FILTRATE PROTEIN 10; GAMMA INTERFERON; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; BACTERIUM CULTURE; COMPARATIVE STUDY; CROSS REACTION; DENDRITIC CELL; HYBRIDOMA; IMMUNOHISTOCHEMISTRY; LEPROSY; MACROPHAGE; MYCOBACTERIUM LEPRAE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SEQUENCE HOMOLOGY; SEROLOGY; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; HUMANS; HYBRIDOMAS; IMMUNE SERA; LEPROSY; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM LEPRAE; MYCOBACTERIUM TUBERCULOSIS; PEPTIDES; RABBITS; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TUBERCULOSIS;

EID: 2542626802     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.6.3161-3170.2004     Document Type: Article

References (49)

1. Andersen, P., A. B. Andersen, A. L. Sorensen, and S. Nagai. 1995. Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice. J. Immunol. 154:3359-3372.
2. Arend, S. M., P. Andersen, K. E. van Meijgaarden, R. L. V. Skjot, J. T. van Dissel, and T. H. M. Ottenhoff. 2000. Detection of active tuberculosis infection by T cell responses to early secreted antigen target 6 kDa protein and culture filtrate protein 10. J. Infect. Dis. 181:1850-1854.
3. Berthet, F.-X., P. B. Rasmussen, I. Rosenkrands, P. Andersen, and B. Gicquel. 1998. A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP10). Microbiology 144:3195-3203.
4. Black, G. F., H. M. Dockrell, A. C. Crampin, S. Floyd, R. E. Weir, L. Bliss, L. Sichali, L. Mwaungulu, H. Kanyongoloka, B. Ngwira, D. K. Warndorff, and P. E. M. Fine. 2001. Patterns and implications of naturally acquired immune responses to environmental and tuberculous mycobacterial antigens in northern Malawi. J. Infect. Dis. 184:322-329.
5. Brock, I., M. E. Munk, A. Kok-Jensen, and P. Andersen. 2001. Performance of whole blood IFN-γ test for tuberculosis based on PPD or the specific antigens ESAT-6 and CFP-10. Int. J. Tuberc. Lung Dis. 5:462-467.
6. Cho, S. N., J. S. Shin, I. H. Choi, S. H. Kim, D. I. Kim, and J. D. Kim. 1988. Detection of phenolic glycolipid I of Mycobacterium leprae and antibodies to the antigen in sera from leprosy patients and their contacts. Yonsei Med. J. 29:219-224.
7. Colangeli, R., J. S. Spencer, P. Bifani, A. Williams, K. Lyashenko, M. A. Keen, P. J. Hill, J. Belisle, and M. L. Gennaro. 2000. MTSA-10, the product of the Rv3874 gene of Mycobacterium tuberculosis, elicits tuberculosis-specific, delayed-type hypersensitivity in guinea pigs. Infect. Immun. 68:990-993.
8. Cole, S. T., R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S. V. Gordon, K. Eiglmeier, S. Gas, C. E. Barry III, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M. A. Quail, M.-A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, S. Squares, R. Squares, J. E. Sulston, K. Taylor, S. Whitehead, and B. G. Barrell. 1998. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393:537-544.
9. Cole, S. T., K. Eiglmeier, J. Parkhill, K. D. James, N. R. Thomson, P. R. Wheeler, N. Honore, T. Garnier, C. Churcher, D. Harris, K. Mungall, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. M. Davies, K. Devlin, S. Duthoy, T. Feltwell, A. Fraser, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, C. Lacroix, J. Maclean, S. Moule, L. Murphy, K. Oliver, M. A. Quail, M. A. Rajandream, K. M. Rutherford, S. Rutter, K. Seeger, S. Simon, M. Simmonds, J. Skelton, R. Squares, S. Squares, K. Stevens, K. Taylor, S. Whitehead, J. R. Woodward, and B. G. Barrell. 2001. Massive gene decay in the leprosy bacillus. Nature 409:1007-1011.
10. DeLisi, C., and J. Berzofsky. 1985. T cell antigenic sites tend to be amphipathic structures. Proc. Natl. Acad. Sci. USA 82:7048-7052.
11. Geluk, A., K. E. van Meijgaarden, K. L. M. C. Franken, Y. W. Subronto, B. Wieles, S. M. Arend, E. P. Sampaio, T. de Boer, W. R. Faber, B. Naafs, and T. H. M. Ottenhoff. 2002. Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis. Infect. Immun. 70:2544-2548.
12. Geluk, A., K. E. van Meijgaarden, K. L. M. C. Franken, B. Wieles, S. M. Arend, W. R. Faber, B. Naafs, and T. H. M. Ottenhoff. 2004. Immunological crossreactivity of the Mycobacterium leprae CFP-10 with its homologue in Mycobacterium tuberculosis. Scand. J. Immunol. 59:66-70.
13. Griffith, I. J., N. Nabavi, Z. Ghogawala, C. G. Chase, M. Rodriquez, D. J. McKean, and L. H. Glimcher. 1988. Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules. J. Exp. Med. 167:541-555.
14. Harboe, M., T. Oettinger, H. G. Wiker, I. Rosenkrands, and P. Andersen. 1996. Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG. Infect. Immun. 64:16-22.
15. Hunter, S. W., B. Rivoire, V. Mehra, B. R. Bloom, and P. J. Brennan. 1990. The major native proteins of the leprosy bacillus. J. Biol. Chem. 265:14065-14068.
16. International Leprosy Association. 2002. Report of the International Leprosy Association Technical Forum. Int. J. Lepr. 70:S3-S62.
17. Jameson, B. A., and H. Wolf. 1988. The antigenic index: a novel algorithm for predicting antigenic determinants. Comput. Applic. Biosci. 4:181-186.
18. Kappler, J. W., B. Skidmore, J. White, and P. Marrack. 1981. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J. Exp. Med. 153:1198-1214.
19. Kim, K. J., C. Kanellopoulos-Langevin, R. Merwin, D. Sachs, and R. Asofsky. 1979. Establishment and characterization of BALB/c lymphoma lines with B cell properties. J. Immunol. 122:549-554.
20. Kyte, J., and R. F. Doolittle. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:105-132.
21. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
22. Mahairas, G. G., P. J. Sabo, M. J. Hickey, D. C. Singh, and C. K. Stover. 1996. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J. Bacteriol. 178:1274-1282.
23. Marques, M. A. M., S. Chitale, P. J. Brennan, and M. C. V. Pessolani. 1998. Mapping and identification of the major cell wall-associated components of Mycobacterium leprae. Infect. Immun. 66:2625-2631.
24. Porathe, J., J. Carlsson, I. Olsson, and G. Belfrage. 1975. Metal chelate affinity chromatography, a new approach to protein fractionation. Nature 258:598-599.
25. Pym, A. S., P. Brodin, L. Majlessi, R. Brosch, C. Demangel, A. Williams, K. E. Griffiths, G. Marchal, C. Leclerc, and S. T. Cole. 2003. Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nat. Med. 5:533-539.
26. Rothbard, J. B., and M. L. Gefter. 1991. Interactions between immunogenic peptides and MHC proteins. Annu. Rev. Immunol. 9:527-565.
27. Rudensky, A. Y., P. Preston-Hurlburt, S.-C. Hong, A. Barlow, and C. A. Janeway. 1991. Sequence analysis of peptides bound to MHC class II molecules. Nature 353:622-627.
28. Sette, A., S. Buus, S. Colon, J. A. Smith, C. Miles, and H. M. Grey. 1987. Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells. Nature 328:395-399.
29. d-binding peptides derived from unrelated protein antigens share a common structural motif. J. Immunol. 141:45-48.
30. Shulman, M., C. D. Wilde, and G. Kohler. 1978. A better cell line for making hybridomas secreting specific antibodies. Nature 276:269-270.
31. Skjot, R. L. V., T. Oettinger, I. Rosenkrands, P. Ravn, I. Brock, S. Jacobsen, and P. Andersen. 2000. Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens. Infect. Immun. 68:214-220.
32. Smith, P. K., R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson, and D. C. Klenk. 1985. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150:76-85.
33. Sorensen, A. L., S. Nagai, G. Houen, P. Andersen, and A. B. Andersen. 1995. Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect. Immun. 63:1710-1717.
34. Spencer, J. S., J. H. Freed, and R. T. Kubo. 1993. Expression and function of mixed isotype class II molecules in normal mice. J. Immunol. 151:6822-6832.
35. Spencer, J. S., M. A. M. Marques, M. C. B. S. Lima, A. P. Junqueira-Kipnis, B. C. Gregory, R. W. Truman, and P. J. Brennan. 2002. Antigenic specificity of the Mycobacterium leprae homologue of ESAT-6. Infect. Immun. 70:1010-1013.
36. Stanley, S. A., S. Raghavan, W. W. Hwang, and J. S. Cox. 2003. Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system. Proc. Natl. Acad. Sci. USA 100:13001-13006.
37. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
38. Truman, R. W., and J. L. Krahenbuhl. 2001. Viable M. leprae as a research reagent. Int. J. Lepr. Other Mycobact. Dis. 69:1-12.
39. van Pinxteren, L. A., P. Ravn, E. M. Agger, J. Pollock, and P. Andersen. 2000. Diagnosis of tuberculosis based on the two specific antigens ESAT-6 and CFP-10. Clin. Diagn. Lab. Immunol. 7:155-160.
40. van Pittius, N. C. G., J. Gamieldien, W. Hide, G. D. Brown, R. J. Siezen, and A. D. Beyers. 2001. The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria. Genome Biol. 2:44.1-44.18.
41. Vekemans, J., C. Lienhardt, J. S. Sillah, J. G. Wheeler, G. P. Lahai, M. T. Doherty, T. Corrah, P. Andersen, K. P. W. J. McAdam, and A. Marchant. 2001. Tuberculosis contacts but not patients have higher gamma interferon responses to ESAT-6 than do community controls in The Gambia. Infect. Immun. 69:6554-6557.
42. Vissa, V. D., and P. J. Brennan. 2002. Impact of the Mycobacterium leprae genome sequence on leprosy research, p. 85-118. In Genomics of GC rich gram-positive bacteria. Caister Academic Press, Wymondham, United Kingdom.
43. Voller, A., D. E. Bidwell, and A. Bartlett. 1979. The enzyme-linked immunoassay (ELISA). Dynatech Laboratories, Inc., Alexandria, Va.
44. Vordermeier, H. M., A. Whelan, P. J. Cockle, L. Farrant, N. Palmer, and R. G. Hewinson. 2001. Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle. Clin. Diagn. Lab. Immunol. 8:571-578.
45. White, J., M. Blackman, J. Bill, J. Kappler, P. Marrack, D. Gold, and W. Born. 1989. Two better cell lines for making hybridomas expressing specific T cell receptors. J. Immunol. 143:1822-1825.
46. World Health Organization. 2003. Leprosy elimination campaigns: impact on case detection. Wkly. Epidemiol. Rec. 78:9-16.
47. World Health Organization. 2002. Leprosy elimination campaigns. Wkly. Epidemiol. Rec. 77:17-20.
48. World Health Organization. 2002. Leprosy. Global situation. Wkly. Epidemiol. Rec. 77:1-8.
49. Yokoyama, W. M. 1997. Production of monoclonal antibodies, p. 2.5.1-2.5.17. In J. E. Coligan, A. M. Druisbeek, D. H. Margulies, E. M. Shevach, and W. Strober (ed.), Current protocols in immunology. John Wiley & Sons, Inc., New York, N.Y.