Detection of active tuberculosis infection by T cell responses to early- secreted antigenic target 6-kDa protein and culture filtrate protein 10

Journal of Infectious Diseases

Volumn 181, Issue 5, 2000, Pages 1850-1854

  Arend, Sandra M ^a   Andersen, Peter ^b   Van Meijgaarden, Krista E ^a   Skjøt, Rikke L V ^b   Subronto, Yanri W ^a,c   Van Dissel, Jaap T ^a   Ottenhoff, Tom H M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b STATENS SERUM INSTITUT   (Denmark)

^c GADJAH MADA UNIVERSITY   (Indonesia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; TUBERCULIN;

ADOLESCENT; ADULT; AGED; ARTICLE; BCG VACCINATION; CELLULAR IMMUNITY; CLINICAL ARTICLE; CROSS REACTION; HUMAN; INFECTION; LYMPHOCYTE ACTIVATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; SCHOOL CHILD; SERODIAGNOSIS; T LYMPHOCYTE; TUBERCULIN TEST; TUBERCULOSIS;

ADOLESCENT; ADULT; AGED; ANTIBODY FORMATION; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BCG VACCINE; CHILD; HUMANS; LYMPHOCYTE ACTIVATION; MIDDLE AGED; ROC CURVE; T-LYMPHOCYTES; TUBERCULIN TEST; TUBERCULOSIS;

EID: 0034042030     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315448     Document Type: Article

References (17)

1. 1. Huebner RE, Schein MF, Bass JB Jr. The tuberculin skin test. Clin Infect Dis 1993; 17:968-75.
2. 2. Mahairas GG, Sabo PJ, Hickey MJ, Singh DC, Stover CK. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J Bacteriol 1996; 178:1274-82.
3. 3. Behr MA, Wilson MA, Gill WP, et al. Comparative genomics of BCG vaccines by whole-genome DNA microarray. Science 1999; 284:1520-3.
4. 4. Harboe M, Oettinger T, Wiker HG, Rosenkrands I, Andersen P. Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG. Infect Immun 1996; 64:16-22.
5. 5. Sørensen AL, Nagai S, Houen G, Andersen P, Andersen ÅB. Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect Immun 1995; 63:1710-7.
6. 6. Andersen P, Andersen ÅB, Sorensen AL, Nagai S. Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice. J Immunol 1995; 154:3359-72.
7. . Pollock JM, Andersen P. The potential of the ESAT-6 antigen secreted by virulent mycobacteria for specific diagnosis of tuberculosis. J Infect Dis 1997; 175:1251-4.
8. 8. Ravn P, Demissie A, Eguale T, et al. Human T cell responses to the ESAT-6 antigen from Mycobacterium tuberculosis. J Infect Dis 1999; 179:637-45.
9. 9. Mustafa AS, Amoudy HA, Wiker HG, et al. Comparison of antigen-specific T-cell responses of tuberculosis patients using complex or single antigens of Mycobacterium tuberculosis. Scand J Immunol 1998; 48:535-43.
10. 10. Ulrichs T, Munk ME, Mollenkopf H, et al. Differential T cell responses to Mycobacterium tuberculosis ESAT6 in tuberculosis patients and healthy donors. Eur J Immunol 1998; 28:3949-58.
11. 11. Berthet FX, Rasmussen PB, Rosenkrands I, Andersen P, Gicquel B. A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CPF-10). Microbiology 1998; 144: 3195-203.
12. 12. Skjot RLV, Oettinger T, Rosenkrands I, et al. Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens. Infect Immun 2000; 68:214-20.
13. 13. van Pinxteren LA, Ravn P, Agger EM, Pollock J, Andersen P. Diagnosis of tuberculosis based on the two specific antigens ESAT-6 and CFP10. Clin Diag Lab Immunol 2000; 7:155-60.
14. 14. Andersen P, Askgaard D, Ljungqvist L, Bennedsen J, Heron I. Proteins released from Mycobacterium tuberculosis during growth. Infect Immun 1991; 59:1905-10.
15. 15. von Reyn CF, Williams DE, Horsburgh Jr CR, et al. Dual skin testing with Mycobacterium avium sensitin and purified protein derivative to discriminate pulmonary disease due to M. avium complex from pulmonary disease due to Mycobacterium tuberculosis. J Infect Dis 1998; 177:730-6.
16. 16. Elhay MJ, Oettinger T, Andersen P. Delayed-type hypersensitivity responses to ESAT-6 and MPT64 from Mycobacterium tuberculosis in the guinea pig. Infect Immun 1999; 66:3454-6.
17. 17. Kamath AT, Feng CG, Macdonald M, Briscoe H, Britton WJ. Differential protective efficacy of DNA vaccines expressing secreted proteins of Mycobacterium tuberculosis. Infect Immun 1999; 67:1702-7.