Apical accumulation of the Drosophila PDGF/VEGF receptor ligands provides a mechanism for triggering localized actin polymerization

Development

Volumn 131, Issue 9, 2004, Pages 1939-1948

  Rosin, Dalia ^a   Schejter, Eyal ^a   Volk, Talila ^a   Shilo, Ben Zion ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Actin organization; Drosophila; Epithelial polarity; PDGF; PVF; PVR; VEGF; Wing epithelium

Indexed keywords

ACTIN; LIGAND; PLATELET DERIVED GROWTH FACTOR RECEPTOR; RNA; VASCULOTROPIN RECEPTOR;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; BIOACCUMULATION; CELL ADHESION; CELL JUNCTION; CELL POLARITY; CELL SECRETION; CONTROLLED STUDY; CYTOSKELETON; DEVELOPMENT; DIMERIZATION; DROSOPHILA; EPITHELIUM; EPITHELIUM CELL; EXTRACELLULAR SPACE; FORELIMB; GENE CONSTRUCT; GENE EXPRESSION; MICROFILAMENT; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PUPATION; REGULATORY MECHANISM; TISSUE DISTRIBUTION; TUMOR GROWTH;

ACTINS; ANIMALS; CELL POLARITY; CYTOSKELETON; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EGG PROTEINS; EMBRYONIC STRUCTURES; EPITHELIAL CELLS; HEPARIN; LIGANDS; PHENOTYPE; PLATELET-DERIVED GROWTH FACTOR; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WING;

ANIMALIA;

EID: 2542582998     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01101     Document Type: Article

References (24)

1. Amann, K. J. and Pollard, T. D. (2000). Cellular regulation of actin network assembly. Curr. Biol. 10, R728-R730.
2. Bilder, D. (2001). PDZ proteins and polarity: functions from the fly. Trends Genet. 17, 511-519.
3. Bilder, D., Li, M. and Perrimon, N. (2000). Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 289, 113-116.
4. Borrmann, C. M., Mertens, C., Schmidt, A., Langbein, L., Kuhn, C. and Franke, W. W. (2000). Molecular diversity of plaques of epithelial-adhering junctions. Ann. New York Acad. Sci. 915, 144-150.
5. Braga, V. M. (2002). Cell-cell adhesion and signalling. Curr. Opin. Cell Biol. 14, 546-556.
6. Cho, N. K., Keyes, L., Johnson, E., Heller, J., Ryner, L., Karim, F. and Krasnow, M. A. (2002). Developmental control of blood cell migration by the Drosophila VEGF pathway. Cell 108, 865-876.
7. Drubin, D. G. and Nelson, W. J. (1996). Origins of cell polarity. Cell 84, 335-344.
8. Duchek, P., Somogyi, K., Jekely, G., Beccari, S. and Rorth, P. (2001). Guidance of cell migration by the Drosophila PDGF/VEGF receptor. Cell 107, 17-26.
9. Fristrom, D., Gotwals, P., Eaton, S., Kornberg, T. B., Sturtevant, M., Bier, E. and Fristrom, J. W. (1994). Blistered: a gene required for vein/intervein formation in wings of Drosophila. Development 120, 2661-2671.
10. Jacob, R. and Naim, H. Y. (2001). Apical membrane proteins are transported in distinct vesicular carriers. Curr. Biol. 11, 1444-1450.
11. Mostov, K. E. and Cardone, M. H. (1995). Regulation of protein traffic in polarized epithelial cells. BioEssays 17, 129-138.
12. Muller, H. A. (2000). Genetic control of epithelial cell polarity: lessons from Drosophila. Dev. Dyn. 218, 52-67.
13. Munier, A. I., Doucet, D., Perrodou, E., Zachary, D., Meister, M., Hoffmann, J. A., Janeway, C. A., Jr and Lagueux, M. (2002). PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae. EMBO Rep. 3, 1195-1200.
14. Nagafuchi, A. (2001). Molecular architecture of adherens junctions. Curr. Opin. Cell Biol. 13, 600-603.
15. Neumann, C. J. and Cohen, S. M. (1997). Long-range action of Wingless organizes the dorso-ventral axis of the Drosophila wing. Development 124, 871-880.
16. Park, J. E., Keller, G. A. and Ferrara, N. (1993a). The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol. Biol. Cell 4, 1317-1326.
17. Park, J. E., Keller, G. A. and Ferrara, N. (1993b). The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol. Biol. Cell 4, 1317-1326.
18. Simons, K. and Ikonen, E. (1997). Functional rafts in cell membranes. Nature 387, 569-572.
19. Strand, D., Jakobs, R., Merdes, G., Neumann, B., Kalmes, A., Heid, H. W., Husmann, I. and Mechler, B. M. (1994). The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain. J. Cell Biol. 127, 1361-1373.
20. Strigini, M. and Cohen, S. M. (2000). Wingless gradient formation in the Drosophila wing. Curr. Biol. 10, 293-300.
21. Tepass, U. (2002). Adherens junctions: new insight into assembly, modulation and function. BioEssays 24, 690-695.
22. Tepass, U., Tanentzapf, G., Ward, R. and Fehon, R. (2001). Epithelial cell polarity and cell junctions in Drosophila. Annu. Rev. Genet. 35, 747-784.
23. Wandinger-Ness, A., Bennett, M. K., Antony, C. and Simons, K. (1990). Distinct transport vesicles mediate the delivery of plasma membrane proteins to the apical and basolateral domains of MDCK cells. J Cell Biol. 111, 987-1000.
24. Watson, K. L., Justice, R. W. and Bryant, P. J. (1994). Drosophila in cancer research: the first fifty tumor suppressor genes. J. Cell Sci. Supplement 18, 19-33.