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Volumn 136, Issue 3, 2004, Pages 393-401

Antiphospholipid syndrome: Multiple mechanisms

Author keywords

Antiphospholipid antibody; Beta 2 glycoprotein I; Lupus anticoagulant haemostasis; Thrombosis

Indexed keywords

ACTIVATED PROTEIN C; APOLIPOPROTEIN A1; BETA2 GLYCOPROTEIN 1; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 8A; BLOOD CLOTTING FACTOR 9A; CARDIOLIPIN; CYCLIC AMP; FATTY ACID BINDING PROTEIN; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 6; KALLIKREIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR; PROTEIN C; PROTEIN S; THROMBIN; THROMBOMODULIN; THROMBOXANE; TISSUE PLASMINOGEN ACTIVATOR; VASCULAR CELL ADHESION MOLECULE 1;

EID: 2542554965     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02497.x     Document Type: Review
Times cited : (105)

References (136)
  • 1
    • 0021029327 scopus 로고
    • Anticardiolipin antibodies: Detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus
    • Harris EN, Gharavi AE, Boey ML et al. Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet 1983; ii:1211-4.
    • (1983) Lancet , vol.2 , pp. 1211-1214
    • Harris, E.N.1    Gharavi, A.E.2    Boey, M.L.3
  • 2
    • 0024427029 scopus 로고
    • Antiphospholipid antibodies and the antiphospholipid syndrome in systemic lupus erythematosus. A prospective analysis of 500 consecutive patients
    • Baltimore
    • Alarcon-Segovia D, Deleze M, Oria CV et al. Antiphospholipid antibodies and the antiphospholipid syndrome in systemic lupus erythematosus. A prospective analysis of 500 consecutive patients. Medicine (Baltimore) 1989; 68:353-65.
    • (1989) Medicine , vol.68 , pp. 353-365
    • Alarcon-Segovia, D.1    Deleze, M.2    Oria, C.V.3
  • 3
    • 0034858414 scopus 로고    scopus 로고
    • Hughes (antiphospholipid) syndrome, clinical features
    • Cuadrado MJ, Hughes GRV Hughes (antiphospholipid) syndrome, clinical features. Rheum Dis Clin North Am 2001; 27:507-24.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 507-524
    • Cuadrado, M.J.1    Hughes, G.R.V.2
  • 4
    • 0021807597 scopus 로고
    • Antibody to cardiolipin as a predictor of fetal distress or death in pregnant patients with systemic lupus erythematosus
    • Lockshin MD, Druzin ML, Goei S et al. Antibody to cardiolipin as a predictor of fetal distress or death in pregnant patients with systemic lupus erythematosus. N Eng J Med 1985; 313:152-6.
    • (1985) N Eng J Med , vol.313 , pp. 152-156
    • Lockshin, M.D.1    Druzin, M.L.2    Goei, S.3
  • 5
    • 0000287488 scopus 로고
    • Hypergammaglobulinaemia, circulating anticoagulant, and biologic false positive Wassermann reaction
    • Laurell B-B, Nilsson IM. Hypergammaglobulinaemia, circulating anticoagulant, and biologic false positive Wassermann reaction. J Laboratory Clin Med 1957; 49:694-707.
    • (1957) J Laboratory Clin Med , vol.49 , pp. 694-707
    • Laurell, B.-B.1    Nilsson, I.M.2
  • 7
    • 0019327041 scopus 로고
    • Possible relationship between lupus inhibitor and recurrent abortion in young women
    • Firkin BG, Howard MA, Radford N. Possible relationship between lupus inhibitor and recurrent abortion in young women. Lancet 1980; ii:366.
    • (1980) Lancet , vol.2 , pp. 366
    • Firkin, B.G.1    Howard, M.A.2    Radford, N.3
  • 8
    • 0021874776 scopus 로고
    • Lupus anticoagulants, an analysis of the clinical and laboratory features of 219 cases
    • Gastineau DA, Kazmier FJ, Nichols WL, Bowie EJW. Lupus anticoagulants, an analysis of the clinical and laboratory features of 219 cases. Am J Hematol 1985; 19:265-75.
    • (1985) Am J Hematol , vol.19 , pp. 265-275
    • Gastineau, D.A.1    Kazmier, F.J.2    Nichols, W.L.3    Bowie, E.J.W.4
  • 9
    • 0022178199 scopus 로고
    • Measurement of anticardiolipin antibodies by enzyme linked immunosorbent assay: Standardisation and quantitation of results
    • Loizou S, McCrea JD, Rudge AC et al. Measurement of anticardiolipin antibodies by enzyme linked immunosorbent assay: standardisation and quantitation of results. Clin Exp Immunol 1985; 62:738-44.
    • (1985) Clin Exp Immunol , vol.62 , pp. 738-744
    • Loizou, S.1    McCrea, J.D.2    Rudge, A.C.3
  • 12
    • 0030941616 scopus 로고    scopus 로고
    • Thrombocytopenia in the antiphospholipid syndrome
    • Cuadrado MJ, Mujic F, Munoz E et al. Thrombocytopenia in the antiphospholipid syndrome. Ann Rheum Dis 1997; 56:194-6.
    • (1997) Ann Rheum Dis , vol.56 , pp. 194-196
    • Cuadrado, M.J.1    Mujic, F.2    Munoz, E.3
  • 13
    • 0013175558 scopus 로고
    • Primary antiphospholipid syndrome: Features of patients with raised anticardiolipin antibodies and no other disorder
    • Mackworth-Young CG, David J, Loizou S, Walport MJ. Primary antiphospholipid syndrome: features of patients with raised anticardiolipin antibodies and no other disorder. Ann Rheum Dis 1987; 26:94.
    • (1987) Ann Rheum Dis , vol.26 , pp. 94
    • Mackworth-Young, C.G.1    David, J.2    Loizou, S.3    Walport, M.J.4
  • 15
    • 0024428788 scopus 로고
    • The 'primary' antiphospholipid syndrome: Major clinical and serological features
    • Baltimore
    • Asherson RA, Khamashta MA, Ordi-Ros J et al. The 'primary' antiphospholipid syndrome: major clinical and serological features. Medicine (Baltimore) 1989; 68:366-74.
    • (1989) Medicine , vol.68 , pp. 366-374
    • Asherson, R.A.1    Khamashta, M.A.2    Ordi-Ros, J.3
  • 16
    • 0025102933 scopus 로고
    • Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in BALB/c mice: A model for autoimmune fetal loss
    • Branch DW, Dudley DJ, Mitchell MD et al. Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in BALB/c mice: a model for autoimmune fetal loss. Am J Obstet Gynecol 1990; 163:210-6.
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 210-216
    • Branch, D.W.1    Dudley, D.J.2    Mitchell, M.D.3
  • 17
    • 0026322836 scopus 로고
    • Induction of antiphospholipid syndrome by passive transfer of anti-cardiolipin antibodies
    • Blank M, Cohen J, Toder V, Shoenfeld Y. Induction of antiphospholipid syndrome by passive transfer of anti-cardiolipin antibodies. Proc Natl Acad Sci USA 1991; 88:3069-73.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3069-3073
    • Blank, M.1    Cohen, J.2    Toder, V.3    Shoenfeld, Y.4
  • 18
    • 0027199779 scopus 로고
    • Anti-cardiolipin antibodies induce pregnancy failure by impairing embryonic implantation
    • Sthoeger ZM, Mozes E, Tartakovsky B. Anti-cardiolipin antibodies induce pregnancy failure by impairing embryonic implantation. Proc Natl Acad Sci USA 1993; 90:6464-7.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6464-6467
    • Sthoeger, Z.M.1    Mozes, E.2    Tartakovsky, B.3
  • 19
    • 0035059266 scopus 로고    scopus 로고
    • The effects of a human IgM monoclonal anticardiolipin antibody on pregnancy in a transgenic mouse model
    • Mason AN, Mageed RA, Mackworth-Young CG. The effects of a human IgM monoclonal anticardiolipin antibody on pregnancy in a transgenic mouse model. Lupus 2001; 10:289-94.
    • (2001) Lupus , vol.10 , pp. 289-294
    • Mason, A.N.1    Mageed, R.A.2    Mackworth-Young, C.G.3
  • 20
    • 0030805883 scopus 로고    scopus 로고
    • Variable effects on murine pregnancy of immunoglobulin G fractions from women with antiphospholipid antibodies
    • Silver RM, Smith LA, Edwin SS e al. Variable effects on murine pregnancy of immunoglobulin G fractions from women with antiphospholipid antibodies. Am J Obstet Gynecol 1997; 177:229-33.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 229-233
    • Silver, R.M.1    Smith, L.A.2    Edwin, S.S.3
  • 21
    • 0026663398 scopus 로고
    • Induction of primary antiphospholipid syndrome in mice by immunisation with a human monoclonal anticardiolipin antibody (H-3)
    • Bakimer R, Fishman P, Blank M et al. Induction of primary antiphospholipid syndrome in mice by immunisation with a human monoclonal anticardiolipin antibody (H-3). J Clin Invest 1992; 89:1558-63.
    • (1992) J Clin Invest , vol.89 , pp. 1558-1563
    • Bakimer, R.1    Fishman, P.2    Blank, M.3
  • 22
    • 0028129636 scopus 로고
    • Antiphospholipid antibodies in an in vivo thrombosis model in mice
    • Pierangeli SS, Harris EN. Antiphospholipid antibodies in an in vivo thrombosis model in mice. Lupus 1994; 3:247-51.
    • (1994) Lupus , vol.3 , pp. 247-251
    • Pierangeli, S.S.1    Harris, E.N.2
  • 23
    • 0025302635 scopus 로고
    • Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor
    • Galli M, Comfurius P, Maassen C et al. Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor. Lancet 1990; 335:1544-7.
    • (1990) Lancet , vol.335 , pp. 1544-1547
    • Galli, M.1    Comfurius, P.2    Maassen, C.3
  • 24
    • 0025332717 scopus 로고
    • Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I (apolipoprotein H)
    • McNeil HP, Simpson RJ, Chesterman CN, Krilis SA. Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I (apolipoprotein H). Proc Natl Acad Sci USA 1990; 87:4120-4.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4120-4124
    • McNeil, H.P.1    Simpson, R.J.2    Chesterman, C.N.3    Krilis, S.A.4
  • 25
    • 0029814955 scopus 로고    scopus 로고
    • Immunology of the antiphospholipid syndrome
    • Roubey RAS. Immunology of the antiphospholipid syndrome. Arthritis Rheum 1996; 39:1444-54.
    • (1996) Arthritis Rheum , vol.39 , pp. 1444-1454
    • Roubey, R.A.S.1
  • 27
    • 0026817042 scopus 로고
    • A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmue disease but not with infection
    • Hunt JE, McNeil HP, Morgan GJ et al. A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmue disease but not with infection. Lupus 1992; 1:75-81.
    • (1992) Lupus , vol.1 , pp. 75-81
    • Hunt, J.E.1    McNeil, H.P.2    Morgan, G.J.3
  • 28
    • 0029897454 scopus 로고    scopus 로고
    • Reactivity to beta 2 glycoprotein I clearly differentiates anticardiolipin antibodies from antiphospholipid syndrome and syphilis
    • Forastiero RR, Martinuzzo ME, Kordich LC et al. Reactivity to beta 2 glycoprotein I clearly differentiates anticardiolipin antibodies from antiphospholipid syndrome and syphilis. Thrombosis Haemostasis 1996;75:717-20.
    • (1996) Thrombosis Haemostasis , vol.75 , pp. 717-720
    • Forastiero, R.R.1    Martinuzzo, M.E.2    Kordich, L.C.3
  • 29
    • 0028045046 scopus 로고
    • Characteristics of HIV and chlorpromazine induced antiphospholipid antibodies: Effect of β2-glycoprotein I on binding to phospholipid
    • Gharavi AE, Sammaritano LR, Wen J et al. Characteristics of HIV and chlorpromazine induced antiphospholipid antibodies: effect of β2-glycoprotein I on binding to phospholipid. J Rheumatol 1984; 21:94-9.
    • (1984) J Rheumatol , vol.21 , pp. 94-99
    • Gharavi, A.E.1    Sammaritano, L.R.2    Wen, J.3
  • 30
    • 0027253088 scopus 로고
    • Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S. an explanation for their pathogenic mechanism?
    • Ousting JD, Derksen RH, Bobbink IW et al. Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S. an explanation for their pathogenic mechanism? Blood 1993; 81:2618-25.
    • (1993) Blood , vol.81 , pp. 2618-2625
    • Ousting, J.D.1    Derksen, R.H.2    Bobbink, I.W.3
  • 31
    • 0035878001 scopus 로고    scopus 로고
    • The clonal analysis of anticardiolipin antibodies in a single patient with primary antiphospholipid syndrome reveals an extreme antibody heterogeneity
    • Lieby P, Soley A, Levallois H et al. The clonal analysis of anticardiolipin antibodies in a single patient with primary antiphospholipid syndrome reveals an extreme antibody heterogeneity. Blood 2001; 97:3820-8.
    • (2001) Blood , vol.97 , pp. 3820-3828
    • Lieby, P.1    Soley, A.2    Levallois, H.3
  • 32
    • 0042832999 scopus 로고    scopus 로고
    • Prevalence and clinical correlations of antibodies against six beta2-glycoprotein-I-related peptides in the antiphospholipid sydrome
    • Shoenfeld Y, Krause I, Kvapil F et al. Prevalence and clinical correlations of antibodies against six beta2-glycoprotein-I-related peptides in the antiphospholipid sydrome. J Clin Immunol 2003; 23:377-83.
    • (2003) J Clin Immunol , vol.23 , pp. 377-383
    • Shoenfeld, Y.1    Krause, I.2    Kvapil, F.3
  • 33
    • 0001400831 scopus 로고
    • A disorder of blood coagulation in systemic lupus erythematosus
    • Lee SL, Saunders M, Kahny HMA. A disorder of blood coagulation in systemic lupus erythematosus. J Clin Invest 1955; 34:1814-22.
    • (1955) J Clin Invest , vol.34 , pp. 1814-1822
    • Lee, S.L.1    Saunders, M.2    Kahny, H.M.A.3
  • 34
    • 0023947097 scopus 로고    scopus 로고
    • Coagulation screen is more specific than the anticardiolipin aantibody ELISA in defining a thrombotic subset of lupus patients
    • Derksen RH, Hasselar P, Blokzijl L et al. Coagulation screen is more specific than the anticardiolipin aantibody ELISA in defining a thrombotic subset of lupus patients. Ann Rheum Dis 1998; 47:364-71.
    • (1998) Ann Rheum Dis , vol.47 , pp. 364-371
    • Derksen, R.H.1    Hasselar, P.2    Blokzijl, L.3
  • 35
    • 0025951058 scopus 로고
    • Lupus anticoagulant IgGs (LA) are not directed to phosholipids only, but to a complex of lipid-bound human prothrombin
    • Bevers EM, Galli M, Barbui T, Comfurius P, Zwaal RF. Lupus anticoagulant IgGs (LA) are not directed to phosholipids only, but to a complex of lipid-bound human prothrombin. Thrombosis Haemostasis 1991; 66:629-32.
    • (1991) Thrombosis Haemostasis , vol.66 , pp. 629-632
    • Bevers, E.M.1    Galli, M.2    Barbui, T.3    Comfurius, P.4    Zwaal, R.F.5
  • 36
    • 0025278465 scopus 로고
    • Inhibition of the tissue factor-factor VII mediated activation of coagulation factor X by a monoclonal antibody expressing lupus anticoagulant activity
    • Skjonsberg OH, Wisloff F, Godal HC. Inhibition of the tissue factor-factor VII mediated activation of coagulation factor X by a monoclonal antibody expressing lupus anticoagulant activity. Thrombosis Res 1990; 58:349-52.
    • (1990) Thrombosis Res , vol.58 , pp. 349-352
    • Skjonsberg, O.H.1    Wisloff, F.2    Godal, H.C.3
  • 37
    • 0037327770 scopus 로고    scopus 로고
    • Factor VII/VIIa: A new antigen in the antiphospholipid antibody syndrome
    • Bidot O, Horstman LL, Huisheng H et al. Factor VII/VIIa: a new antigen in the antiphospholipid antibody syndrome. Br J Haematol 2003; 120:618-26.
    • (2003) Br J Haematol , vol.120 , pp. 618-626
    • Bidot, O.1    Horstman, L.L.2    Huisheng, H.3
  • 38
    • 0034865785 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the coagulation cascade
    • Angles-Cano E, Guillin M-C. Antiphospholipid antibodies and the coagulation cascade. Rheum Dis Clin North Am 2001; 27:573-86.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 573-586
    • Angles-Cano, E.1    Guillin, M.-C.2
  • 39
    • 0020082613 scopus 로고
    • Prekallikrein inhibition assocoated with the lupus anticoagulant
    • Sanfelippo MJ, Drayna CJ. Prekallikrein inhibition assocoated with the lupus anticoagulant. Am J Clin Pathol 1982; 77:275-9.
    • (1982) Am J Clin Pathol , vol.77 , pp. 275-279
    • Sanfelippo, M.J.1    Drayna, C.J.2
  • 40
    • 0028365677 scopus 로고
    • Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies
    • Kornberg A, Blank M, Kaufman S, Shoenfeld Y. Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies. J Immunol 1994; 153:1328-32.
    • (1994) J Immunol , vol.153 , pp. 1328-1332
    • Kornberg, A.1    Blank, M.2    Kaufman, S.3    Shoenfeld, Y.4
  • 42
    • 0031886679 scopus 로고    scopus 로고
    • The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome
    • Amengual O, Atsuni T, Khamashta MA, Hughes GRV. The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome. Thrombosis Haemostasis 1998; 79:276-81.
    • (1998) Thrombosis Haemostasis , vol.79 , pp. 276-281
    • Amengual, O.1    Atsuni, T.2    Khamashta, M.A.3    Hughes, G.R.V.4
  • 43
    • 0038810153 scopus 로고    scopus 로고
    • Beta-2-glycoprotein I expression on monocytes is increased in antiphospholipid antibody syndrome and correlates with tissue factor expression
    • Conti F, Sorice M, Circella A et al. Beta-2-glycoprotein I expression on monocytes is increased in antiphospholipid antibody syndrome and correlates with tissue factor expression. Clin Exp Immunol 2003; 132:509-16.
    • (2003) Clin Exp Immunol , vol.132 , pp. 509-516
    • Conti, F.1    Sorice, M.2    Circella, A.3
  • 44
    • 0037386632 scopus 로고    scopus 로고
    • Specificities, properties and clinical significance of antiprothrombin antibodies
    • Amengual O, Atsumi T, Koike T. Specificities, properties and clinical significance of antiprothrombin antibodies Arthritis Rheum. 2003; 48:886-95.
    • (2003) Arthritis Rheum , vol.48 , pp. 886-895
    • Amengual, O.1    Atsumi, T.2    Koike, T.3
  • 45
    • 0031757439 scopus 로고    scopus 로고
    • Anti-thrombin but not 'pure' anti-cardiolipin antibodies are associated with the clinical features of the antiphospholipid antibody syndrome
    • Sorice M, Pittone V, Circella A et al. Anti-thrombin but not 'pure' anti-cardiolipin antibodies are associated with the clinical features of the antiphospholipid antibody syndrome. Thrombosis Haemostasis 1998; 80:16-22.
    • (1998) Thrombosis Haemostasis , vol.80 , pp. 16-22
    • Sorice, M.1    Pittone, V.2    Circella, A.3
  • 46
    • 0034791684 scopus 로고    scopus 로고
    • Anti-prothrombin antibodies combined with lupus anti-coagulant activity is an essential risk factor for venous thromboembolism in patients with systemic lupus erythematosus
    • Nojima J, Kuratsune H, Suehisa E et al. Anti-prothrombin antibodies combined with lupus anti-coagulant activity is an essential risk factor for venous thromboembolism in patients with systemic lupus erythematosus. Br J Heamatol 2001; 114:647-54.
    • (2001) Br J Heamatol , vol.114 , pp. 647-654
    • Nojima, J.1    Kuratsune, H.2    Suehisa, E.3
  • 47
    • 0036036951 scopus 로고    scopus 로고
    • Acquired protein C resistance is associated with the co-existence of anti-prothrombin antibodies and lupus anticoagulant activity in patients with systemic lupus erythematosus
    • Nojima J, Kuratsune H, Suehisa E et al. Acquired protein C resistance is associated with the co-existence of anti-prothrombin antibodies and lupus anticoagulant activity in patients with systemic lupus erythematosus. Br J Haematol 2002; 118:577-83.
    • (2002) Br J Haematol , vol.118 , pp. 577-583
    • Nojima, J.1    Kuratsune, H.2    Suehisa, E.3
  • 48
    • 0029896410 scopus 로고    scopus 로고
    • Autoantibodies to phospholipid-binding proteins in patients with thrombosis and phospholipid-reactive antibodies
    • Pengo V, Biasiolo A, Brocco T et al. Autoantibodies to phospholipid-binding proteins in patients with thrombosis and phospholipid-reactive antibodies. Thrombosis Haemostasis 1996; 75:721-4.
    • (1996) Thrombosis Haemostasis , vol.75 , pp. 721-724
    • Pengo, V.1    Biasiolo, A.2    Brocco, T.3
  • 49
    • 0030608864 scopus 로고    scopus 로고
    • Relationship of anti-beta2-glycoprotein I and anti prothrombin antibodies to thrombosis and pregnancy loss in patients with antiphospholipid antibodies
    • Forastiero R, Martinuzzo M, Cerrato G et al. Relationship of anti-beta2-glycoprotein I and anti prothrombin antibodies to thrombosis and pregnancy loss in patients with antiphospholipid antibodies. Thrombosis Haemostasis 1997; 78:1008-114.
    • (1997) Thrombosis Haemostasis , vol.78 , pp. 1008-1114
    • Forastiero, R.1    Martinuzzo, M.2    Cerrato, G.3
  • 50
    • 0031968872 scopus 로고    scopus 로고
    • The contribution of anti-prothrombin antibodies to lupus anticoagulant activity - Discrimination between functional and non-functional anti-prothrombin antibodies
    • Horbach D, van Oort E, Derksen R, de Groot P. The contribution of anti-prothrombin antibodies to lupus anticoagulant activity - discrimination between functional and non-functional anti-prothrombin antibodies. Thrombosis Haemostasis 1998; 79:790-5.
    • (1998) Thrombosis Haemostasis , vol.79 , pp. 790-795
    • Horbach, D.1    Van Oort, E.2    Derksen, R.3    De Groot, P.4
  • 51
    • 0030937274 scopus 로고    scopus 로고
    • Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies
    • Galli M, Beretta G, Daldossi M et al. Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies. Thrombosis Haemostasis 1997; 77:486-91.
    • (1997) Thrombosis Haemostasis , vol.77 , pp. 486-491
    • Galli, M.1    Beretta, G.2    Daldossi, M.3
  • 52
    • 0030457493 scopus 로고    scopus 로고
    • Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus: Comparison between different assays for the detection of antiphospholipid antibodies
    • Horbach D, van Oort E, Donders R et al. Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus: comparison between different assays for the detection of antiphospholipid antibodies. Thrombosis Haemostasis 1996; 76:916-24.
    • (1996) Thrombosis Haemostasis , vol.76 , pp. 916-924
    • Horbach, D.1    Van Oort, E.2    Donders, R.3
  • 53
    • 0033711669 scopus 로고    scopus 로고
    • Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant
    • Atsumi T, Ieko M, Bertolaccini ML et al. Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant. Arthritis Rheum 2000; 43:1982-93.
    • (2000) Arthritis Rheum , vol.43 , pp. 1982-1993
    • Atsumi, T.1    Ieko, M.2    Bertolaccini, M.L.3
  • 54
    • 0035893021 scopus 로고    scopus 로고
    • Identification of antithrombin antibodies in the antiphospholipid syndrome that interfere with the inactivation of thrombin by antithrombin
    • Hwang K-K, Grossman JM, Visvanathan S et al. Identification of antithrombin antibodies in the antiphospholipid syndrome that interfere with the inactivation of thrombin by antithrombin. J Immunol 2001; 167:7192-8.
    • (2001) J Immunol , vol.167 , pp. 7192-7198
    • Hwang, K.-K.1    Grossman, J.M.2    Visvanathan, S.3
  • 55
    • 0028266134 scopus 로고
    • Autoantibodies to heparin from patients with antiphospholipid antibody syndrome inhibit formation of antithrombin III-thrombin complexes
    • Shibata S, Harpel PC, Gharavi AE et al. Autoantibodies to heparin from patients with antiphospholipid antibody syndrome inhibit formation of antithrombin III-thrombin complexes. Blood 1994; 83:2532-40.
    • (1994) Blood , vol.83 , pp. 2532-2540
    • Shibata, S.1    Harpel, P.C.2    Gharavi, A.E.3
  • 57
    • 0024433923 scopus 로고
    • Impaired catalytic function of activated protein C. a new manifestation of lupus anticoagulant
    • Marciniak E, Romond EH. Impaired catalytic function of activated protein C. a new manifestation of lupus anticoagulant. Blood 1989; 74:2426-32.
    • (1989) Blood , vol.74 , pp. 2426-2432
    • Marciniak, E.1    Romond, E.H.2
  • 58
    • 0026786517 scopus 로고
    • Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells
    • Borrell EM, Sala N, de Castellarnau C et al. Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells. Thrombosis Haemostasis 1992; 68:268-72.
    • (1992) Thrombosis Haemostasis , vol.68 , pp. 268-272
    • Borrell, E.M.1    Sala, N.2    De Castellarnau, C.3
  • 59
    • 0028804699 scopus 로고
    • On the role of phosphtidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies
    • Smirnov MD, Triplett DT, Comp PC et al. On the role of phosphtidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies. J Clin Invest 1995; 95:309-16.
    • (1995) J Clin Invest , vol.95 , pp. 309-316
    • Smirnov, M.D.1    Triplett, D.T.2    Comp, P.C.3
  • 60
    • 0025001363 scopus 로고
    • Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies
    • Malia RG, Kirchens S, Greaves M, Preston FE. Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies. Br J Haematol 1990; 76:101-7.
    • (1990) Br J Haematol , vol.76 , pp. 101-107
    • Malia, R.G.1    Kirchens, S.2    Greaves, M.3    Preston, F.E.4
  • 61
    • 0004609028 scopus 로고
    • Human thrombomodulin is inhibited by IgG from two patients with non-specific anticoagulants
    • Comp PC, DeBault LE, Esmon NL, Esmon CT. Human thrombomodulin is inhibited by IgG from two patients with non-specific anticoagulants. Blood 1983; 62:299a.
    • (1983) Blood , vol.62
    • Comp, P.C.1    DeBault, L.E.2    Esmon, N.L.3    Esmon, C.T.4
  • 62
    • 0022486133 scopus 로고
    • An IgM lupus anticoagulant that neutralizes the enhancing effect of phospholipid on purified endothelial thrombomodulin activity. A mechanism for thrombosis
    • Freyssinet JM, Wiesel M-L, Gauchy J et al. An IgM lupus anticoagulant that neutralizes the enhancing effect of phospholipid on purified endothelial thrombomodulin activity. A mechanism for thrombosis. Thrombosis Haemostasis 1986; 55:309-13.
    • (1986) Thrombosis Haemostasis , vol.55 , pp. 309-313
    • Freyssinet, J.M.1    Wiesel, M.-L.2    Gauchy, J.3
  • 63
    • 0021958273 scopus 로고
    • Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases anti-activator activity
    • Sakata Y, Curriden S, Lawrence D et al. Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases anti-activator activity. Proc Natl Acad Sci USA 1985; 82:1121-5.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 1121-1125
    • Sakata, Y.1    Curriden, S.2    Lawrence, D.3
  • 64
    • 0021928672 scopus 로고
    • Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium
    • Van Hinsberg VWM, Bertina RM, van Wijngaarden A et al. Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium. Blood 1986; 65:444-51.
    • (1986) Blood , vol.65 , pp. 444-451
    • Van Hinsberg, V.W.M.1    Bertina, R.M.2    Van Wijngaarden, A.3
  • 65
    • 0025215541 scopus 로고
    • Tissue plasminogen activator inhibitor in patients with systemic lupus erythematosus and thrombosis
    • Violi F, Ferro D, Valesini G et al. Tissue plasminogen activator inhibitor in patients with systemic lupus erythematosus and thrombosis. Br Med J 1990; 309:1099-102.
    • (1990) Br Med J , vol.309 , pp. 1099-1102
    • Violi, F.1    Ferro, D.2    Valesini, G.3
  • 66
    • 0025854755 scopus 로고
    • The fibrinolytic response to venous occlusion and the natural anticoagulants in patients with antiphospholipid antibodies both with and without systemic lupus erythematosus
    • Keeling DM, Campbell SJ, Mackie IJ et al. The fibrinolytic response to venous occlusion and the natural anticoagulants in patients with antiphospholipid antibodies both with and without systemic lupus erythematosus. Br J Haematol 1991; 77:354-9.
    • (1991) Br J Haematol , vol.77 , pp. 354-359
    • Keeling, D.M.1    Campbell, S.J.2    Mackie, I.J.3
  • 67
    • 1542373659 scopus 로고    scopus 로고
    • Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: Evidence of interaction between the antibodies and the catalytic domain oftPA in two patients
    • in press
    • Cugno M, Cabibbe M, Galli M et al. Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: evidence of interaction between the antibodies and the catalytic domain of tPA in two patients. Blood 2004; 00:000-000. in press
    • (2004) Blood
    • Cugno, M.1    Cabibbe, M.2    Galli, M.3
  • 68
    • 0028903573 scopus 로고
    • Endothelium-derived haemostatic factors and the antiphospholipid syndrome
    • Mackworth-Young CG, Andreotti F, Harmer IJ et al. Endothelium-derived haemostatic factors and the antiphospholipid syndrome. Br J Rheumatol 1995; 34:201-6.
    • (1995) Br J Rheumatol , vol.34 , pp. 201-206
    • Mackworth-Young, C.G.1    Andreotti, F.2    Harmer, I.J.3
  • 69
    • 0026744185 scopus 로고
    • Clustering of lipid-bound annexin V may explain its anticoagulant effect
    • Andree HA, Stuart MC, Hermens WT et al. Clustering of lipid-bound annexin V may explain its anticoagulant effect. J Biol Chem 1992; 267:17907-12.
    • (1992) J Biol Chem , vol.267 , pp. 17907-17912
    • Andree, H.A.1    Stuart, M.C.2    Hermens, W.T.3
  • 70
    • 0028022531 scopus 로고
    • Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody
    • Matsuda J, Saitoh N, Gohchi K et al. Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody. Am J Hematol 1994; 47:56-8.
    • (1994) Am J Hematol , vol.47 , pp. 56-58
    • Matsuda, J.1    Saitoh, N.2    Gohchi, K.3
  • 71
    • 0042925727 scopus 로고    scopus 로고
    • Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: Evidence from atomic force microscopy and functional assay
    • Rand JH, Wu XX, Quinn AS et al. Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: evidence from atomic force microscopy and functional assay. Am J Pathol 2003; 163:1193-200.
    • (2003) Am J Pathol , vol.163 , pp. 1193-1200
    • Rand, J.H.1    Wu, X.X.2    Quinn, A.S.3
  • 72
    • 0041425259 scopus 로고    scopus 로고
    • Anti-annexin A5 antibodies in reproductive failures in relation to antiphospholipid antibodies and phosphatidylserine
    • Arai T, Matsubayashi H, Sugi T et al. Anti-annexin A5 antibodies in reproductive failures in relation to antiphospholipid antibodies and phosphatidylserine. Am J Reprod Immunol 2003; 50:202-8.
    • (2003) Am J Reprod Immunol , vol.50 , pp. 202-208
    • Arai, T.1    Matsubayashi, H.2    Sugi, T.3
  • 73
    • 0028846868 scopus 로고
    • Autoantibodies to phosphatidylethanolamine (PE) recognize a kininogen-PE complex
    • Sugi T, McIntyre JA. Autoantibodies to phosphatidylethanolamine (PE) recognize a kininogen-PE complex Blood. 1995; 86:3083-9.
    • (1995) Blood , vol.86 , pp. 3083-3089
    • Sugi, T.1    McIntyre, J.A.2
  • 74
    • 0242349755 scopus 로고    scopus 로고
    • Sulfatides: Targets for anti-phospholipid antibodies
    • Merten M, Motamedy S, Ramamurthy S et al. Sulfatides: targets for anti-phospholipid antibodies. Circulation 2003; 108:2082-7.
    • (2003) Circulation , vol.108 , pp. 2082-2087
    • Merten, M.1    Motamedy, S.2    Ramamurthy, S.3
  • 75
    • 2142773072 scopus 로고    scopus 로고
    • Autoimmune antiphospholipid antibodies impair the inhibition of activated factor X by protein Z/protein Z-dependent protease inhibitor
    • Forastiero RR, Martinuzzo ME, Lu L, Broze GJ. Autoimmune antiphospholipid antibodies impair the inhibition of activated factor X by protein Z/protein Z-dependent protease inhibitor. J Thrombosis Haemostasis 2003; 1:1764-70.
    • (2003) J Thrombosis Haemostasis , vol.1 , pp. 1764-1770
    • Forastiero, R.R.1    Martinuzzo, M.E.2    Lu, L.3    Broze, G.J.4
  • 76
    • 0035726226 scopus 로고    scopus 로고
    • Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis
    • Joseph JE, Harrison P, Mackie IJ et al. Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis. Br J Haematol 2001; 115:451-9.
    • (2001) Br J Haematol , vol.115 , pp. 451-459
    • Joseph, J.E.1    Harrison, P.2    Mackie, I.J.3
  • 77
    • 0031876263 scopus 로고    scopus 로고
    • Effects of human monoclonal anticardiolipin antibodies on platelet function and on tissue factor expression on monocytes
    • Reverter JC, Tassies D, Font J et al. Effects of human monoclonal anticardiolipin antibodies on platelet function and on tissue factor expression on monocytes. Arthritis Rheum 1998; 41:1420-7.
    • (1998) Arthritis Rheum , vol.41 , pp. 1420-1427
    • Reverter, J.C.1    Tassies, D.2    Font, J.3
  • 78
    • 0036882165 scopus 로고    scopus 로고
    • Effects of beta2-glycoprotein I and monoclonal anticardiolipin antibodies in platelet interaction with subendothelium under flow conditions
    • Font J, Esinosa G, Tassies D et al. Effects of beta2-glycoprotein I and monoclonal anticardiolipin antibodies in platelet interaction with subendothelium under flow conditions. Arthritis Rheum 2002; 46:3283-9.
    • (2002) Arthritis Rheum , vol.46 , pp. 3283-3289
    • Font, J.1    Esinosa, G.2    Tassies, D.3
  • 79
    • 0031594519 scopus 로고    scopus 로고
    • Effect of anticardiolipin/ beta2-glycoprotein I complexes on production of thromboxane A2 by platelets from patients with antiphospholipid syndrome
    • Robbins DL, Leung S, Miller-Blair DJ et al. Effect of anticardiolipin/ beta2-glycoprotein I complexes on production of thromboxane A2 by platelets from patients with antiphospholipid syndrome. J Rheumatol 1998; 25:51-6.
    • (1998) J Rheumatol , vol.25 , pp. 51-56
    • Robbins, D.L.1    Leung, S.2    Miller-Blair, D.J.3
  • 80
    • 12244286755 scopus 로고    scopus 로고
    • Cyclic AMP agonists inhibit antiphospholipid/beta2-glycoprotein I induced synthesis of human platelet thromboxane A2 in vitro
    • Opara R, Robbins DL, Ziboh VA, Cyclic AMP agonists inhibit antiphospholipid/beta2-glycoprotein I induced synthesis of human platelet thromboxane A2 in vitro. J Rheumatol 2003; 30:55-9.
    • (2003) J Rheumatol , vol.30 , pp. 55-59
    • Opara, R.1    Robbins, D.L.2    Ziboh, V.A.3
  • 81
    • 0141445991 scopus 로고    scopus 로고
    • Dimers of β2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein e receptor 2′
    • Lutters BCH, Derksen RHWM, Tekelenburg WL et al. Dimers of β2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2′. J Biol Chem 2003; 278:33831-8.
    • (2003) J Biol Chem , vol.278 , pp. 33831-33838
    • Lutters, B.C.H.1    Derksen, R.H.W.M.2    Tekelenburg, W.L.3
  • 82
    • 0001807359 scopus 로고    scopus 로고
    • Mechanisms of thrombosis in the antiphospholipid syndrome: Binding to platelets
    • Khamashta, MA, ed. Springer Verlag
    • Reverter JC, Tassies D. Mechanisms of thrombosis in the antiphospholipid syndrome: binding to platelets. In: Hughes Syndrome, Antiphospholipid Syndrome. Khamashta, MA, ed. Springer Verlag, 2000:pp 290-8.
    • (2000) Hughes Syndrome, Antiphospholipid Syndrome , pp. 290-298
    • Reverter, J.C.1    Tassies, D.2
  • 83
    • 0028218483 scopus 로고
    • Anti-glycoprotein IIb/IX and IIb/IIIa antibodies in patients with antiphospholipid antibodies
    • Galli M, Daldossi M, Barbui T. Anti-glycoprotein IIb/IX and IIb/IIIa antibodies in patients with antiphospholipid antibodies. Thrombosis Haemostasis 1994; 71:571-5.
    • (1994) Thrombosis Haemostasis , vol.71 , pp. 571-575
    • Galli, M.1    Daldossi, M.2    Barbui, T.3
  • 84
    • 0030861626 scopus 로고    scopus 로고
    • Specific antiplatelet glycoprotein autoantibodies are associated with the thrombocytopenia of primary antiphospholipid syndrome
    • Godeau B, Piette J-C, Fromont P et al. Specific antiplatelet glycoprotein autoantibodies are associated with the thrombocytopenia of primary antiphospholipid syndrome. Br J Haematol 1997; 98:873-9.
    • (1997) Br J Haematol , vol.98 , pp. 873-879
    • Godeau, B.1    Piette, J.-C.2    Fromont, P.3
  • 85
    • 0019491415 scopus 로고
    • Arterial thrombosis, intrauterine death and 'lupus' anticoagulant: Detection of immunoglobulin interfering with prostacyclin formation
    • Carreras LO, Defreyn G, Machin SJ et al. Arterial thrombosis, intrauterine death and 'lupus' anticoagulant: detection of immunoglobulin interfering with prostacyclin formation. Lancet 1981; i:244-6.
    • (1981) Lancet , vol.1 , pp. 244-246
    • Carreras, L.O.1    Defreyn, G.2    Machin, S.J.3
  • 86
    • 0023932436 scopus 로고
    • Effects of the lupus anticoagulant in patients with systemic lupus erythematosus in endothelial cell prostacyclin release and procoagulant activity
    • Rustin MHA, Bull HA, Machin SJ et al. Effects of the lupus anticoagulant in patients with systemic lupus erythematosus in endothelial cell prostacyclin release and procoagulant activity. J Invest Dermatol 1988; 90:744-8.
    • (1988) J Invest Dermatol , vol.90 , pp. 744-748
    • Rustin, M.H.A.1    Bull, H.A.2    Machin, S.J.3
  • 87
    • 0024559587 scopus 로고
    • Endothelial prostacyclin relaese in systemic lupus erythematosus
    • Coade SB, van Haaren E, Loizou S et al. Endothelial prostacyclin relaese in systemic lupus erythematosus. Thrombosis Haemostasis 1989; 61:97-100.
    • (1989) Thrombosis Haemostasis , vol.61 , pp. 97-100
    • Coade, S.B.1    Van Haaren, E.2    Loizou, S.3
  • 88
    • 0037215922 scopus 로고    scopus 로고
    • Endothelium as a target for antiphospholipid antibodies
    • Riboldi P, Gerosa M, Raschi E et al. Endothelium as a target for antiphospholipid antibodies. Immunobiology 2003; 207:29-36.
    • (2003) Immunobiology , vol.207 , pp. 29-36
    • Riboldi, P.1    Gerosa, M.2    Raschi, E.3
  • 89
    • 0023944144 scopus 로고
    • Measurement and characterisation of circulating anti-endothelial cell IgG in connective tissue diseases
    • Rosenbaum J, Pottinger BE, Woo P et al. Measurement and characterisation of circulating anti-endothelial cell IgG in connective tissue diseases. Clin Exp Immunol 1988; 72:450-6.
    • (1988) Clin Exp Immunol , vol.72 , pp. 450-456
    • Rosenbaum, J.1    Pottinger, B.E.2    Woo, P.3
  • 90
    • 0023790693 scopus 로고
    • Relationship between anticardiolipin and anti-endothelial cell antibodies in systemic lupus erythematosus
    • Vismara A, Meroni PL, Tincani A et al. Relationship between anticardiolipin and anti-endothelial cell antibodies in systemic lupus erythematosus. Clin Exp Immunol 1988; 74:247-53.
    • (1988) Clin Exp Immunol , vol.74 , pp. 247-253
    • Vismara, A.1    Meroni, P.L.2    Tincani, A.3
  • 91
    • 0025230915 scopus 로고
    • Cross reactivity of antibodies directed against cardiolipin, DNA, endothelial cells and blood platelets
    • Hassalaar P, Derksen RHWM, Blokzijl L, de Groot PG. Cross reactivity of antibodies directed against cardiolipin, DNA, endothelial cells and blood platelets. Thrombosis Haemostasis 1990; 63:169-73.
    • (1990) Thrombosis Haemostasis , vol.63 , pp. 169-173
    • Hassalaar, P.1    Derksen, R.H.W.M.2    Blokzijl, L.3    De Groot, P.G.4
  • 92
    • 0028941808 scopus 로고
    • Relationship between antiphospholipid and anti-endothelial cell antibodies III. β2 glycoprotein I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules
    • Del Papa N, Guidali L, Spatola L et al. Relationship between antiphospholipid and anti-endothelial cell antibodies III. β2 glycoprotein I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules. Clin Exp Rheumatol 1995; 13:179-85.
    • (1995) Clin Exp Rheumatol , vol.13 , pp. 179-185
    • Del Papa, N.1    Guidali, L.2    Spatola, L.3
  • 93
    • 0028883356 scopus 로고
    • Activation of cultured vascular endothelial cells by antiphospholipid antibodies
    • Simantov R, LaSala JM, Lo SK et al. Activation of cultured vascular endothelial cells by antiphospholipid antibodies. J Clin Invest 1995; 96:2211-9.
    • (1995) J Clin Invest , vol.96 , pp. 2211-2219
    • Simantov, R.1    LaSala, J.M.2    Lo, S.K.3
  • 94
    • 0033197971 scopus 로고    scopus 로고
    • GDKV-induced antiphospholipid antibodies enhance thrombosis and activate endothelial cells in vivo and in vitro
    • Gharavi AE, Pierangeli SS, Colden-Stanfield M et al. GDKV-induced antiphospholipid antibodies enhance thrombosis and activate endothelial cells in vivo and in vitro. J. Immunol 1999; 163:2922-7.
    • (1999) J Immunol , vol.163 , pp. 2922-2927
    • Gharavi, A.E.1    Pierangeli, S.S.2    Colden-Stanfield, M.3
  • 95
    • 0033586656 scopus 로고    scopus 로고
    • Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
    • Pierangeli SS, Colden-Stanfield M, Liu JH et al. Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo. Circulation 1999; 99:1997-2002.
    • (1999) Circulation , vol.99 , pp. 1997-2002
    • Pierangeli, S.S.1    Colden-Stanfield, M.2    Liu, J.H.3
  • 96
    • 0032502289 scopus 로고    scopus 로고
    • Differential effects of anti-beta 2 glycoprotein I antibodies on endothelial cells and on the manifestations of experimental antiphospholipid syndrome
    • George J, Blank Y, Levy P et al. Differential effects of anti-beta 2 glycoprotein I antibodies on endothelial cells and on the manifestations of experimental antiphospholipid syndrome. Circulation 1998; 97:900-6.
    • (1998) Circulation , vol.97 , pp. 900-906
    • George, J.1    Blank, Y.2    Levy, P.3
  • 97
    • 0033826480 scopus 로고    scopus 로고
    • Endothelial activation by aPL. a potential pathogenetic mechanism for the clinical manifestations of the syndrome
    • Meroni PL, Raschi E, Camera M et al. Endothelial activation by aPL. a potential pathogenetic mechanism for the clinical manifestations of the syndrome. J Autoimmun 2000; 15:237-40.
    • (2000) J Autoimmun , vol.15 , pp. 237-240
    • Meroni, P.L.1    Raschi, E.2    Camera, M.3
  • 98
    • 0036847630 scopus 로고    scopus 로고
    • NFκB is an essential intermediate in the activation of endothelial cells by anti-β2-glycoprotein I antibodies
    • Dunoyer-Geindre S, de Moerloose P. Galve-de Rochemonteix B et al. NFκB is an essential intermediate in the activation of endothelial cells by anti-β2-glycoprotein I antibodies. Thrombosis Haemostasis 2002; 88:851-7.
    • (2002) Thrombosis Haemostasis , vol.88 , pp. 851-857
    • Dunoyer-Geindre, S.1    De Moerloose, P.2    Galve-de Rochemonteix, B.3
  • 99
    • 0034685886 scopus 로고    scopus 로고
    • High affinity binding of β2-glycoprotein I to human endothelial cells is mediated by annexin II
    • Ma K, Simantov R, Jing-Chuan Z et al High affinity binding of β2-glycoprotein I to human endothelial cells is mediated by annexin II. J Biol Chem 2000; 275:15541-8.
    • (2000) J Biol Chem , vol.275 , pp. 15541-15548
    • Ma, K.1    Simantov, R.2    Jing-Chuan, Z.3
  • 100
    • 0032700453 scopus 로고    scopus 로고
    • Increased levels of tissue factor mRNA in mononuclear blood cells of patients with primary antiphospholipid syndrome
    • Dobado-Berrios PM, Lopez-Pedrera C, Velasco F et al. Increased levels of tissue factor mRNA in mononuclear blood cells of patients with primary antiphospholipid syndrome. Thrombosis Haemostasis 1999; 82:1578-82.
    • (1999) Thrombosis Haemostasis , vol.82 , pp. 1578-1582
    • Dobado-Berrios, P.M.1    Lopez-Pedrera, C.2    Velasco, F.3
  • 101
    • 0030240765 scopus 로고    scopus 로고
    • Anti-phospholipid antibodies bind to apoptotic, but not viable, thymocytes in a β2-glycoprotein I-dependent manner
    • Price BE, Jauch J, Shia MA et al. Anti-phospholipid antibodies bind to apoptotic, but not viable, thymocytes in a β2-glycoprotein I-dependent manner. J Immunol 1996; 157:2201-8.
    • (1996) J Immunol , vol.157 , pp. 2201-2208
    • Price, B.E.1    Jauch, J.2    Shia, M.A.3
  • 102
    • 0032065912 scopus 로고    scopus 로고
    • Arterial disease and thrombosis in the antiphospholipid syndrome: A pathogenic role for endothelin I
    • Atsumi T, Khamashta MA, Haworth RS et al. Arterial disease and thrombosis in the antiphospholipid syndrome: a pathogenic role for endothelin I. Arthritis Rheum 1998; 41:800-7.
    • (1998) Arthritis Rheum , vol.41 , pp. 800-807
    • Atsumi, T.1    Khamashta, M.A.2    Haworth, R.S.3
  • 103
    • 0026459695 scopus 로고
    • Risk factors for coronary artery disease in patients with systemic lupus erythematosus
    • Petri M, Perez-Gutthann S, Spence D, Hochberg MC. Risk factors for coronary artery disease in patients with systemic lupus erythematosus. Am J Med 1992; 93:513-9.
    • (1992) Am J Med , vol.93 , pp. 513-519
    • Petri, M.1    Perez-Gutthann, S.2    Spence, D.3    Hochberg, M.C.4
  • 104
    • 2542639654 scopus 로고
    • Fasting lipids and anticardiolipin antibodies as risk factors for vascular disease in systemic lupus erythematosus
    • MacGregor AJ, Dhillon VB, Binder A et al. Fasting lipids and anticardiolipin antibodies as risk factors for vascular disease in systemic lupus erythematosus. Ann Rhem Dis 1992; 38:529-34.
    • (1992) Ann Rhem Dis , vol.38 , pp. 529-534
    • MacGregor, A.J.1    Dhillon, V.B.2    Binder, A.3
  • 105
    • 0036049364 scopus 로고    scopus 로고
    • Anti-β2-glycoprotein I autoantibodies and atherosclerosis
    • Matsuura E, Kobayashi K, Kasahara J et al. Anti-β2-glycoprotein I autoantibodies and atherosclerosis. Intern Rev Immunol 2002; 21:51-66.
    • (2002) Intern Rev Immunol , vol.21 , pp. 51-66
    • Matsuura, E.1    Kobayashi, K.2    Kasahara, J.3
  • 106
    • 0027457735 scopus 로고    scopus 로고
    • Crossreaction between antibodies to oxidised low-density lipoprotein and to cardiolipin in systemic lupus erythematosus
    • Vaarala O, Alfthan M, Jauhiainen M. et al. Crossreaction between antibodies to oxidised low-density lipoprotein and to cardiolipin in systemic lupus erythematosus. Lancet 2003; 341:923-5.
    • (2003) Lancet , vol.341 , pp. 923-925
    • Vaarala, O.1    Alfthan, M.2    Jauhiainen, M.3
  • 107
    • 0031821374 scopus 로고    scopus 로고
    • Lack of crossreaction between antibodies to β2-glycoprotein I and oxidised low-density lipoprotein in patients with antiphospholipid syndrome
    • Tinahones FJ, Cuadrado MJ, Khamashta MA et al. Lack of crossreaction between antibodies to β2-glycoprotein I and oxidised low-density lipoprotein in patients with antiphospholipid syndrome. Br J Rheumatol 1998; 37:746-9.
    • (1998) Br J Rheumatol , vol.37 , pp. 746-749
    • Tinahones, F.J.1    Cuadrado, M.J.2    Khamashta, M.A.3
  • 108
    • 0034990570 scopus 로고    scopus 로고
    • A specific ligand for β2-glycoprotein I mediates autoantibody-dependent uptake of oxidised low density lipoprotein by macrophages
    • Kobayashi K, Matsuura E, Liu Q et al. A specific ligand for β2-glycoprotein I mediates autoantibody-dependent uptake of oxidised low density lipoprotein by macrophages. J Lipid Res 2001; 42:697-709.
    • (2001) J Lipid Res , vol.42 , pp. 697-709
    • Kobayashi, K.1    Matsuura, E.2    Liu, Q.3
  • 109
    • 0032530883 scopus 로고
    • Induction of early atherosclerosis in LDL-receptor-deficient mice immunised with β2-glycoprotein I
    • George J, Harats D, Gilburd B et al. Induction of early atherosclerosis in LDL-receptor-deficient mice immunised with β2-glycoprotein I. Circulation 1988; 98:1108-15.
    • (1988) Circulation , vol.98 , pp. 1108-1115
    • George, J.1    Harats, D.2    Gilburd, B.3
  • 110
    • 0028104884 scopus 로고
    • Antiphospholipid antibodies, thrombosis and atherosclerosis in systemic lupus erythematosus: A unifying 'membrane stress syndrome' hypothesis
    • Ames PRJ. Antiphospholipid antibodies, thrombosis and atherosclerosis in systemic lupus erythematosus: a unifying 'membrane stress syndrome' hypothesis. Lupus 1994; 3:371-7.
    • (1994) Lupus , vol.3 , pp. 371-377
    • Ames, P.R.J.1
  • 111
    • 0041569770 scopus 로고    scopus 로고
    • Cross-reactivity between anti-cardiolipin, anti-high-density lipiprotein and anti-apolipoprotein A-I IgG antibodies in patients with systemic lupus erythematosus and primary antiphospholipid syndrome
    • Delgado Alves J, Kumar S, Isenberg DA. Cross-reactivity between anti-cardiolipin, anti-high-density lipiprotein and anti-apolipoprotein A-I IgG antibodies in patients with systemic lupus erythematosus and primary antiphospholipid syndrome. Rheumatology 2003; 42:893-9.
    • (2003) Rheumatology , vol.42 , pp. 893-899
    • Delgado Alves, J.1    Kumar, S.2    Isenberg, D.A.3
  • 112
    • 0037216764 scopus 로고    scopus 로고
    • Antiphospholipid antibodies: Are they proatherogenic or an epiphenomenon of atherosclerosis?
    • Sherer Y, Shoenfeld Y. Antiphospholipid antibodies: are they proatherogenic or an epiphenomenon of atherosclerosis? Immunobiology 2003; 207:13-6.
    • (2003) Immunobiology , vol.207 , pp. 13-16
    • Sherer, Y.1    Shoenfeld, Y.2
  • 114
    • 0035043316 scopus 로고    scopus 로고
    • Placentation, antiphospholipid syndrome and pregnancy outcome
    • Stone S, Khamashta MA, Poston L. Placentation, antiphospholipid syndrome and pregnancy outcome. Lupus 2001; 10:67-74.
    • (2001) Lupus , vol.10 , pp. 67-74
    • Stone, S.1    Khamashta, M.A.2    Poston, L.3
  • 116
    • 0347579311 scopus 로고    scopus 로고
    • Placental pathology in antiphospholipid antibody syndrome
    • Khamashta MA, ed. London: Springer Verlag
    • Parke AL. Placental pathology in antiphospholipid antibody syndrome. In: Khamashta MA, ed. Hughes Syndrome, Antiphospholipid Syndrome. London: Springer Verlag, 2000:281-9.
    • (2000) Hughes Syndrome, Antiphospholipid Syndrome , pp. 281-289
    • Parke, A.L.1
  • 117
    • 0032874599 scopus 로고    scopus 로고
    • Affinity purified human antiphospholipid antibodies bind normal term placenta
    • Donohoe S, Kingdom JCP, Mackie IJ. Affinity purified human antiphospholipid antibodies bind normal term placenta. Lupus 1999; 8:525-31.
    • (1999) Lupus , vol.8 , pp. 525-531
    • Donohoe, S.1    Kingdom, J.C.P.2    Mackie, I.J.3
  • 118
    • 0032569480 scopus 로고    scopus 로고
    • Action of anticardiolipin and antibodies to beta 2 glycoprotein I on trophoblast proliferation as a mechanism for fetal death
    • Chamley LW, Duncalf AM, Mitchell MD et al. Action of anticardiolipin and antibodies to beta 2 glycoprotein I on trophoblast proliferation as a mechanism for fetal death. Lancet 1998; 352:1037-8.
    • (1998) Lancet , vol.352 , pp. 1037-1038
    • Chamley, L.W.1    Duncalf, A.M.2    Mitchell, M.D.3
  • 119
    • 0034121236 scopus 로고    scopus 로고
    • Antiphospholipid antibodies affect trophoblast gonadotrophin secretion and invasiveness by binding directly and through adhered beta 2 glycoprotein I
    • Di Simone N, Meroni PL, Del Papa N et al. Antiphospholipid antibodies affect trophoblast gonadotrophin secretion and invasiveness by binding directly and through adhered beta 2 glycoprotein I. Arthritis Rheum 2000; 43:140-53.
    • (2000) Arthritis Rheum , vol.43 , pp. 140-153
    • Di Simone, N.1    Meroni, P.L.2    Del Papa, N.3
  • 120
    • 0030443981 scopus 로고    scopus 로고
    • Defective maternal-fetal interaction in a murine autoimmune model
    • Tartakovski B, Bermas BL, Sthoeger Z et al. Defective maternal-fetal interaction in a murine autoimmune model. Human Reprod 1996; 11:2408-11.
    • (1996) Human Reprod , vol.11 , pp. 2408-2411
    • Tartakovski, B.1    Bermas, B.L.2    Sthoeger, Z.3
  • 121
    • 0037148520 scopus 로고    scopus 로고
    • Complement C3 activation is required for antiphospholipid antibody-induced fetal loss
    • Holers VM, Girardi G, Mo L et al. Complement C3 activation is required for antiphospholipid antibody-induced fetal loss. J Exp Med 2002; 195:211-20.
    • (2002) J Exp Med , vol.195 , pp. 211-220
    • Holers, V.M.1    Girardi, G.2    Mo, L.3
  • 122
    • 0346969977 scopus 로고    scopus 로고
    • Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
    • Girardi G, Berman J, Redecha P et al. Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest 2003; 112:1644-54.
    • (2003) J Clin Invest , vol.112 , pp. 1644-1654
    • Girardi, G.1    Berman, J.2    Redecha, P.3
  • 123
    • 0034695647 scopus 로고    scopus 로고
    • A critical role for the murine complement receptor Crry in fetomaternal tolerance
    • Xu C, Mao D, Holers VM et al. A critical role for the murine complement receptor Crry in fetomaternal tolerance. Science 2000; 287:498-501.
    • (2000) Science , vol.287 , pp. 498-501
    • Xu, C.1    Mao, D.2    Holers, V.M.3
  • 124
    • 0025823651 scopus 로고
    • Histopathological findings in placentae from patients with intra-uterine fetal death and antiphospholipid antibodies
    • Out HJ, Kooijman CD, Bruinse HW, Derksen RH. Histopathological findings in placentae from patients with intra-uterine fetal death and antiphospholipid antibodies. Eur J Obstet Gynecol Reprod Biol 1991; 41:179-86.
    • (1991) Eur J Obstet Gynecol Reprod Biol , vol.41 , pp. 179-186
    • Out, H.J.1    Kooijman, C.D.2    Bruinse, H.W.3    Derksen, R.H.4
  • 125
    • 0031873355 scopus 로고    scopus 로고
    • Placental pathology in systemic lupus erythematosus: A prospective study
    • Magid MS, Kaplan C, Sammaritano LR et al. Placental pathology in systemic lupus erythematosus: a prospective study. Am J Obstet Gynecol 1998; 179:226-34.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 226-234
    • Magid, M.S.1    Kaplan, C.2    Sammaritano, L.R.3
  • 126
    • 0026706529 scopus 로고
    • Antiphospholipid antibodies and complement activation in patients with cerebral ischaemia
    • Davis WD, Brey RL. Antiphospholipid antibodies and complement activation in patients with cerebral ischaemia. Clin Exp Immunol 1992; 10:455-60.
    • (1992) Clin Exp Immunol , vol.10 , pp. 455-460
    • Davis, W.D.1    Brey, R.L.2
  • 127
    • 0034100612 scopus 로고    scopus 로고
    • Detection of complement-fixing antiphospholipid antibodies in association with thrombosis
    • Munakata Y, Saito T, Seino J et al. Detection of complement-fixing antiphospholipid antibodies in association with thrombosis. Thrombosis Haemostasis 2000; 83:728-31.
    • (2000) Thrombosis Haemostasis , vol.83 , pp. 728-731
    • Munakata, Y.1    Saito, T.2    Seino, J.3
  • 128
    • 10744223871 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke
    • Levine SR, Brey RL, Tilley BC et al. Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke. J Am Med Assoc 2004; 291:576-84.
    • (2004) J Am Med Assoc , vol.291 , pp. 576-584
    • Levine, S.R.1    Brey, R.L.2    Tilley, B.C.3
  • 129
    • 0030875741 scopus 로고    scopus 로고
    • Monoclonal antiphosphatidylserine antibodies react directly with feline and murine central nervous system
    • Kent M, Vogt E, Rote NS. Monoclonal antiphosphatidylserine antibodies react directly with feline and murine central nervous system. J Rheumatol 1997; 24:1725-33.
    • (1997) J Rheumatol , vol.24 , pp. 1725-1733
    • Kent, M.1    Vogt, E.2    Rote, N.S.3
  • 130
    • 0032173353 scopus 로고    scopus 로고
    • Serum anti-beta2-glycoprotein I antibodies from patients with antiphospholipid antibody syndrome bind central nervous system cells
    • Caronti B, Calderaro C, Alessandri C et al. Serum anti-beta2-glycoprotein I antibodies from patients with antiphospholipid antibody syndrome bind central nervous system cells. J Autoimmun 1998; 11:425-9.
    • (1998) J Autoimmun , vol.11 , pp. 425-429
    • Caronti, B.1    Calderaro, C.2    Alessandri, C.3
  • 131
    • 0032908439 scopus 로고    scopus 로고
    • Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes
    • Chapman J, Cohen-Armon M, Shoenfeld Y, Korczyn AD. Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes. Lupus 1999; 8:127-33.
    • (1999) Lupus , vol.8 , pp. 127-133
    • Chapman, J.1    Cohen-Armon, M.2    Shoenfeld, Y.3    Korczyn, A.D.4
  • 132
    • 0038607739 scopus 로고    scopus 로고
    • Neuronal-binding antibodies from patients with antiphospholipid syndrome induce cognitive deficits following intrathecal passive transfer
    • Shoenfeld Y, Nahum A, Korczyn AD et al. Neuronal-binding antibodies from patients with antiphospholipid syndrome induce cognitive deficits following intrathecal passive transfer. Lupus 2003; 12:436-42.
    • (2003) Lupus , vol.12 , pp. 436-442
    • Shoenfeld, Y.1    Nahum, A.2    Korczyn, A.D.3
  • 133
    • 0029884938 scopus 로고    scopus 로고
    • A study of sixty pregnancies with the antiphospholipid syndrome
    • Lima F, Khamashta MA, Buchanan NMM et al. A study of sixty pregnancies with the antiphospholipid syndrome. Clin Exp Rheumatol 1996; 14:131-6.
    • (1996) Clin Exp Rheumatol , vol.14 , pp. 131-136
    • Lima, F.1    Khamashta, M.A.2    Buchanan, N.M.M.3
  • 134
    • 0030970221 scopus 로고    scopus 로고
    • Anaesthesia and antiphospholipid syndrome - A review of 20 obstetric patients
    • Ringrose DK. Anaesthesia and antiphospholipid syndrome - a review of 20 obstetric patients. Int J Obstet Anaesth 1997; 6:107-11.
    • (1997) Int J Obstet Anaesth , vol.6 , pp. 107-111
    • Ringrose, D.K.1
  • 135
    • 0030015654 scopus 로고    scopus 로고
    • Coexistence of familial antiphospholipid syndrome and factor V Leiden: Impact on thrombotic diathesis
    • Brenner B, Vulfons SL, Lanir N, Nahir M. Coexistence of familial antiphospholipid syndrome and factor V Leiden: impact on thrombotic diathesis. Br J Haematol 1996; 94:166-7.
    • (1996) Br J Haematol , vol.94 , pp. 166-167
    • Brenner, B.1    Vulfons, S.L.2    Lanir, N.3    Nahir, M.4
  • 136
    • 0030756898 scopus 로고    scopus 로고
    • Thrombosis in the young: Epidemiology and risk factors. A focus on venous thrombosis
    • Rosendaal F. Thrombosis in the young: epidemiology and risk factors. A focus on venous thrombosis. Thrombosis Haemostasis 1997; 78:1-6.
    • (1997) Thrombosis Haemostasis , vol.78 , pp. 1-6
    • Rosendaal, F.1


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