Bone morphogenic protein-2 gene therapy for mandibular distraction osteogenesis

Annals of Plastic Surgery

Volumn 52, Issue 6, 2004, Pages 585-591

  Ashinoff, Russell L ^a   Cetrulo Jr , Curtis L ^a   Galiano, Robert D ^a   Dobryansky, Michael ^a   Bhatt, Kirit A ^a   Ceradini, Daniel J ^a   Michaels V, Joseph ^a   McCarthy, Joseph G ^a   Gurtner, Geoffrey C ^a   Csank, George A ^b  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

BMP 2; Distraction osteogenesis; Gene therapy

Indexed keywords

ADENOVIRUS VECTOR; BONE MORPHOGENETIC PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE DEVELOPMENT; BONE MINERALIZATION; BONE MORPHOGENETIC PROTEIN 2 GENE; BONE RADIOGRAPHY; CONTROLLED STUDY; DISTRACTION OSTEOGENESIS; FRACTURE; GENE; GENE THERAPY; MALE; MANDIBLE; MANDIBULAR DISTRACTION OSTEOGENESIS; MORPHOMETRICS; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT; TREATMENT FAILURE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; BONE MORPHOGENETIC PROTEINS; GENE THERAPY; IMMUNOBLOTTING; MALE; MANDIBLE; OSTEOGENESIS, DISTRACTION; RATS; RATS, SPRAGUE-DAWLEY; TRANSFORMING GROWTH FACTOR BETA;

EID: 2542548265     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.sap.0000123023.28874.1e     Document Type: Article

References (23)

1. Imola MJ, Hamlar DD, Thatcher G, et al. The versatility of distraction osteogenesis in craniofacial surgery. Arch Facial Plast Surg. 2002;4:8-19.
2. McCarthy JG, Stelnicki EJ, Mehrara BJ, et al. Distraction osteogenesis of the craniofacial skeleton. Plast Reconstr Surg. 2001;107:1812-1827.
3. Mundy GR, Chen D, Zhao M, et al. Growth regulatory factors and bone. Rev Endocr Metab Disord. 2001;2:105-115.
4. ten Dijke P, Fu J, Schaap P, et al. Signal transduction of bone morphogenetic proteins in osteoblast differentiation. J Bone Joint Surg Am. 2003;85-A(suppl 3):34-38.
5. Schilephake H. Bone growth factors in maxillofacial skeletal reconstruction. Int J Oral Maxillofac Surg. 2002;31:469-484.
6. Campisi P, Hamdy RC, Lauzier D, et al. Expression of bone morphogenetic proteins during mandibular distraction osteogenesis. Plast Reconstr Surg. 2003;111:201-208.
7. Campisi P, Hamdy RC, Lauzier D, et al. Overview of the radiology, histology, and bone morphogenetic protein expression during distraction osteogenesis of the mandible. J Otolaryngol. 2002;31:281-286.
8. Rauch F, Lauzier D, Croteau S, et al. Temporal and spatial expression of bone morphogenetic protein-2, -4, and -7 during distraction osteogenesis in rabbits. Bone. 2000;27:453-459.
9. Yazawa M, Kishi K, Nakajima H, et al. Expression of bone morphogenetic proteins during mandibular distraction osteogenesis in rabbits. J Oral Maxillofac Surg. 2003;61:587-592.
10. Li G, Bouxsein ML, Luppen C, et al. Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis. J Orthop Res. 2002;20:779-788.
11. Bostrom M, Lane JM, Tomin E, et al. Use of bone morphogenetic protein-2 in the rabbit ulnar nonunion model. Clin Orthop. 1996;327:272-282.
12. Cook SD, Baffes GC, Wolfe MW, et al. Recombinant human bone morphogenetic protein-7 induces healing in a canine long-bone segmental defect model. Clin Orthop. 1994;301:302-312.
13. Cook SD, Wolfe MW, Salkeld SL, et al. Effect of recombinant human osteogenic protein-1 on healing of segmental defects in non-human primates. J Bone Joint Surg Am. 1995;77:734-750.
14. Gerhart TN, Kirker-Head CA, Kriz MJ, et al. Healing segmental femoral defects in sheep using recombinant human bone morphogenefic protein. Clin Orthop. 1993;293:317-326.
15. Baltzer AW, Lattermann C, Whalen JD, et al. Genetic enhancement of fracture repair: healing of an experimental segmental defect by adenoviral transfer of the BMP-2 gene. Gene Ther. 2000;7:734-739.
16. Lieberman JR, Daluiski A, Stevenson S, et al. The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats. J Bone Joint Surg Am. 1999;81:905-917.
17. Gysin R, Wergedal JE, Sheng MH, et al. Ex vivo gene therapy with stromal cells transduced with a retroviral vector containing the BMP4 gene completely heals critical size calvarial defect in rats. Gene Ther. 2002;9:991-999.
18. Alden TD, Beres EJ, Laurent JS, et al. The use of bone morphogenetic protein gene therapy in craniofacial bone repair. J Craniofac Surg. 2000;11:24-30.
19. Tsuchida H, Hashimoto J, Crawford E, et al. Engineered allogeneic mesenchymal stem cells repair femoral segmental defect in rats. J Orthop Res. 2003;21:44-53.
20. Oyama M, Tatlock A, Fukuta S, et al. Retrovirally transduced bone marrow stromal cells isolated from a mouse model of human osteogenesis imperfecta (oim) persist in bone and retain the ability to form cartilage and bone after extended passaging. Gene Ther. 1999;6:321-329.
21. Wang JC, Kanim LE, Yoo S, et al. Effect of regional gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats. J Bone Joint Surg Am. 2003;85(-A):905-911.
22. Baltzer AW, Lattermann C, Whalen JD, et al. Potential role of direct adenoviral gene transfer in enhancing fracture repair. Clin Orthop. 2000;379(suppl):S120-125.
23. Khan SN, Hidaka C, Sandhu HS, et al. Gene therapy for spine fusion. Orthop Clin North Am. 2000;31:473-484.