CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia

Journal of Cell Biology

Volumn 132, Issue 3, 1996, Pages 437-450

  Parkos, Charles A ^a,b   Colgan, Sean P ^b   Liang, Tony W ^a   Nusrat, Asma ^a   Bacarra, Abraham E ^a   Carnes, Denice K ^a   Madara, James L ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; CD47 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; INTEGRIN; INTERLEUKIN 4; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY C5 D5; UNCLASSIFIED DRUG;

ARTICLE; CELL INTERACTION; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; MONOLAYER CULTURE; NEUTROPHIL CHEMOTAXIS; NORMAL HUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANALYSIS OF VARIANCE; ANTIGENS, CD; ANTIGENS, CD11; ANTIGENS, CD18; ANTIGENS, CD47; CARRIER PROTEINS; CELL ADHESION; CELL LINE; CELL MEMBRANE; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; COLON; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIUM; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; INTERFERON TYPE II; INTESTINAL MUCOSA; INTESTINES; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; NEUTROPHILS; PROTEIN STRUCTURE, SECONDARY;

EID: 0030019862     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.132.3.437     Document Type: Article

References (54)

1. Aebersold, R., H. J. Leavitt, R. A. Saavedra, L. E. Hood, and S. B. H Kent 1987 Internal amino acid sequence analysis of proteins separated by one or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose. Proc Natl. Acad Sci. USA. 84:6940-6974.
2. Augeron, C., and C. Laboisse, L. 1984. Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. Cancer Research. 44:3961-3969
3. Avent, N., P. A Judson, S. F. Parsons, G. Mallinson, D. J. Anstee, M. J. Tanner, P R. Evans, E Hodges, A. G Maciver, and C. Holmes. 1988. Monoclonal antibodies that recognize different membrane proteins that are deficient in Rh null human erythrocytes. One group of antibodies reacts with a variety of cells and tissues whereas the other group is erythroid-specific. Biochem. J. 251.499-505.
4. Barnstable, C. J., W. F. Bodmer, G. Brown, G. Galfre, C. Milstein, A. F Williams, and A Ziegler 1978. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens - new tools for genetic analysis. Cell 14:9-20.
5. Bevilacqua, M. P., S. Stengelin, M. A Gimbrone, and B. Seed. 1989. Endothelial leukocyte adhesion molecule-1: an mducible receptor for neutrophils related to complement regulatory proteins and lectins Science (Wash. DC). 243.1160-1165.
6. Bradford, M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
7. Brown, E., L. Hooper, T. Ho, and H. Gresham. 1990. Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins. J. Cell Biol. 111:2785-2794.
8. Campbell, I. G., P. S. Freemont, W Foulkes, and J. Trowsdale. 1992. An ovarian tumor marker with homology to vaccinia virus contains an IgV-like region and multiple transmembrane domains. Cancer Res. 52:5416-5420.
9. Carreno, M. P., H. D. Gresham, and E J. Brown. 1993. Isolation of leukocyte response integrin: a novel RGD-binding protein involved in regulation of phagocytic function. Clin. Immunol. Immunopathol. 69:43-51
10. Colgan, S. P., C. A. Parkos, C. Delp, M A. Arnaout, and J. L. Madara, 1993. Neutrophil migration across cultured intestinal epithelial monolayers is modulated by epithelial exposure to IFN-γ in a highly polarized fashion J. Cell Biol. 120:785-798.
11. Colgan, S. P., M. P. Resnick, C A Parkos, A. E. Bacarra, C. Delp-Archer, P. W. Weller, and J. L. Madara. 1994. Interleukin-4 directly modulates function of a model intestinal epithelia. J. Immunol. 153:2122-2129.
12. Colgan, S. P., C. A. Parkos, D. K. McGuirk, H. R. Brady, A. A. Papayianni, G. Frendl, and J L. Madara. 1995. Receptors involved in carbohydrate binding modulate intestinal epithelial-neutrophil interactions. J. Biol Chem. 270:10531-10539.
13. Cooper, D., F. P. Lindberg, J R. Gamble, E. J. Brown, and M. A. Vadas 1995. Transendothelial migration of neutrophils involves integrin-associated protein (CD47). Proc. Natl. Acad. Sci. USA 92:3978-3982.
14. de Fourgerolles, A., S. A. Stacker, R. Schwarting, and T A. Springer. 1991. Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1. J. Exp. Med. 174.253-267.
15. Dharmsathaphorn, K., and J. L. Madara. 1990. Established cell lines as model systems for electrolyte transport studies. Methods Enzymol 192: 354-389.
16. Dharmsathaphorn, K., K. G. Mandel, J. McRoberts, L. D. Tisdale, and H Masui. 1984. A human colonic tumor cell line that maintains vectorial electrolyte transport Am. J. Physiol 246:6204-6208.
17. Diamond, M. S., D. E. Staunton, A. R de Fougerolles, S. A. Stacker, J Garcia-Aguilar, M. L. Hibbs, and T A. Springer. 1990. ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18).J. Cell Biol. 111.3129-3139.
18. Donuwitz, M., and M. J. Welsh. 1987. In Physiology of the Gastrointestinal Tract. Vol. 2. L. R Johnson, editor. Raven Press, NY. 1351-1388.
19. Evans, C. W., J E. Taylor, J. D. Walker, and N. L. Simmons. 1983. Transepithelial chemotaxis of rat peritoneal exudate cells. Br. J. Exp. Pathol. 64:644-654
20. Favaloro, E. J. 1993. Differential expression of surface antigens on activated endothelium. Immunol Cell Biol. 71.571-581.
21. Gimbrone, M. A. 1976. Culture of vascular endothelium. In Progress in Hemostasis and Thrombosis. T Spaet, editor. Grune & Stratton Inc., NY. 1-28.
22. Gresham, H. D., J. L Goodwin, P. M Allen, D C. Anderson, and E. J. Brown, 1989. A novel member of the integrin receptor family mediates Arg-Gly-Asp-stimulated neutrophil phagocytosis J. Cell Biol. 108.1935-1943
23. Gresham, H. D , S. P. Adams, and E. J. Brown. 1992. Ligand binding specificity of the leukocyte response integrin expressed by human neutrophils. J Biol Chem. 267.13895-13902
24. Henson, P., and Z G Oades. 1975. Stimulation of human neutrophils by soluble and insoluble immunoglobulin aggregates. J Clin. Invest. 56: 1053-1061.
25. Kaoutzani, P., C A. Parkos, C. Delp-Archer, and J L. Madara. 1993 Isolation of plasma membrane fractions from the intestinal epithelial model T84 Am. J Physiol 264 (Cell Physiol.) 33:C1327-C1335.
26. Kumar, N. B., T. T Nostrant, and H. D. Appelman. 1982. The histopathologic spectrum of acute self-limited colitis (acute infectious type colitis). Am. J Surg. Pathol 6:523-529.
27. Lane, W S , A Galat, M. W. Harding, and S. L. Schreiber 1991. Complete amino acid sequence of the FK106 and rapamycin binding protein, FKBP, isolated from calf thymus. J Prot. Chem 10:151-160.
28. Lindberg, F P, H D, Gresham, E. Schwarz, and E. J Brown 1993. Molecular cloning of integrin-associated protein an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding J. Cell Biol. 123:485-496.
29. Lindberg, F. P., D. M. Lublin, M J Telen, R A, Veile, Y. E. Miller, H. Donis-Keller, and E. J. Brown. 1994. Rh-related antigen CD47 is the signaltransducer integrin-associated protein. J. Biol. Chem. 269:1567-1570.
30. Lo, S. K., G. A. van Seventer, S. Levin, and S. D Wright. 1989. Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands. J. Immunol. 143 3325-3329
31. Madara, J. L , S. P. Colgan, A Nusrat, C. Delp, and C. A. Parkos 1992. A simple approach to measurement of electrical parameters of cultured epithelial monolayers: use in assessing neutrophil epithelial interactions. J. Tiss. Cult Methods. 14:209-216.
32. - secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue. J. Clin. Invest 89:1938-1944.
33. Madara, J. L., T. W. Patapoff, B. Gillece-Castro, S. P. Colgan, C. A. Parkos, C. Delp, and R. J. Mrsny. 1993. 5′-AMP is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 epithelial monolayers. J. Clin. Invest. 91:2320-2325.
34. Mawby, W. J , C. H. Holmes, D. J Anstee, F. A. Spring, and M. J. Tanner. 1994. Isolation and characterization of CD47 glycoprotein: a multispanning membrane protein which is the same as integrin-associated protein (IAP) and the ovarian tumour marker OA3. Biochem J. 304:525-520
35. McCormick, B. A., S. P. Colgan, C. Delp-Archer, S. I. Miller, and J. L. Madara. 1993. Salmonella typhimurium attachment to human intestinal epithelial monolayers: Transcellular signalling to subepithelial neutrophils. J. Cell Biol. 123:895-907.
36. McCormick, B. A., P. M. Hofman, J. Kim, D. K. Carnes, S. I. Miller, and J. L. Madara. 1996. Surface attachment of Salmonella Typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils. J Cell Biol. In press.
37. Nash, S., J. Stafford, and J. L. Madara. 1987. Effects of polymorphonuclear leukocyte transmigration on barrier function of cultured intestinal epithelial monolayers. J. Clin. Invest. 80:1104-1113.
38. Nash, S., J. Stafford, and J. L. Madara. 1988. The selective and superoxide-independent disruption of intestinal epithelial tight junctions during leukocyte transmigration. Lab. Invest. 59:531-537
39. Parham, P. 1983. Preparation and purification of active fragments from mouse monoclonal antibodies. In Immunological Methods in Biomedical Sciences. D. M. Weir, C. Blackwell, and L. Herzenberg, editors. Blackwell, Oxford. 14.1-14.2.
40. Parkos, C. A., C. G. Cochrane, M Schmitt, and A. J. Jesaitis 1985. Regulation of the oxidative response of human granulocytes to chemoattractants: no evidence for stimulated traffic of redox enzymes between endo and plasma membranes. J. Biol. Chem. 260:6541-6547.
41. Parkos, C A., C. Delp, M. A. Arnaout, and J. L. Madara. 1991. Neutrophil migration across a cultured intestinal epithelium: dependence on a CD11b/CD18-mediated event and enhanced efficiency in the physiologic direction. J. Clin. Invest. 88.1605-1612.
42. Parkos, C. A., S. P. Colgan, and J. L. Madara. 1994. Interactions of neutrophils with epithelial cells: lessons learned from the intestine. J. Amer. Soc. Nephrol. 5:138-152.
43. Parkos, C. A., S. P. Colgan, A. E. Bacarra, A. Nusrat, C. Delp-Archer, S. Carlson, H. C. D. Su, and J. L. Madara. 1995. Intestinal epithelia (T84) possess basolateral ligands for CD11b/CD18 mediated neutrophil adherence. Am J. Physiol 268:C472-C479.
44. Parsons, P. E., K. Sugahara, G. R. Cott, R. J. Mason, and P M Henson. 1987. The effect of neutrophil migration and prolonged neutrophil contact on epithelial permeability. Am. J. Pathol. 129.302-312.
45. Rosales, C., H. D. Gresham, and E. J Brown. 1992. Expression of the 50-kDa integrin-associated protein on myeloid cells and erythrocytes. J Immunol 149:2759-2764.
46. Schwartz, M. A., E. J. Brown, and B. Fazeli. 1993. A 50-kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelial cells. J. Biol. Chem 268:19931-19934.
47. Senior, R. M., H D. Gresham, G. L. Griffin, E. J. Brown, and A E. Chung. 1992 Entactin stimulates neutrophil adhesion and chemotaxis through interactions between its Arg-Gly-Asp (RGD) domain and the leukocyte response integrin. J. Clin. Invest. 90:2251-2257.
48. Smith, C. W., S. D. Marlin, R. Rothlein, C. Toman, and D. C. Anderson. 1989. Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro. J. Clin. Invest. 83:2008-2017.
49. Spertini, O., G. S. Kansas, J. M. Munro, J D. Griffin, and T F Tedder. 1991. Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin. Nature (Lond.). 349.691-694.
50. Springer, T. A. 1990. Adhesion receptors of the immune system. Nature (Lond.). 346:425-434.
51. Strohmeier, G. R., S. M. Reppert, W. I. Lencer, and J. L. Madara 1995. The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia. J. Biol. Chem. 270:2387-2394.
52. Wright, S. D., P. E. Rao, W. C. van Voorhis, L. S. Craigmyle, K. Iida, M. A. Talle, E. F. Westberg, G. Goldstein, and S. C. Silverstein. 1983. Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies. Proc. Natl. Acatl. Sci. USA. 80:5699-5703.
53. Yardley, J H. 1986. Pathology of idiopathic inflammatory bowel disease and relevance of specific cell findings: an overview In Recent Developments in the Therapy of Inflammatory Bowel Disease. J. H. Yardley, editor. Johns Hopkins University Press, Baltimore, MD. 3-9.
54. Zhou, M., and E. J. Brown. 1993. Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst. J. Exp. Med. 178:1165-1174.