Characterization of the HSD17B4 gene: D-specific multifunctional protein 2/17β-hydroxysteroid dehydrogenase IV

Journal of Steroid Biochemistry and Molecular Biology

Volumn 69, Issue 1-6, 1999, Pages 441-446

  Möller, Gabriele ^a   Leenders, Frauke ^b   Van Grunsven, Elisabeth G ^c   Dolez, Vincent ^d   Qualmann, Britta ^a   Kessels, Michael M ^a   Markus, Monika ^a   Krazeisen, Antje ^a   Husen, Bettina ^e   Wanders, Ronald J A ^c   De Launoit, Yvan ^d   Adamski, Jerzy ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d FREE UNIVERSITY OF BRUSSELS   (Belgium)

^e UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; ENOYL COENZYME A HYDRATASE; ISOENZYME; STEROL CARRIER PROTEIN; TESTOSTERONE 17BETA DEHYDROGENASE;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CONFERENCE PAPER; ENZYME ACTIVITY; ENZYME ASSAY; EXON; GENE ISOLATION; GENE MUTATION; INTRON; NUCLEOTIDE SEQUENCE; PEROXISOME; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; TISSUE SPECIFICITY; ZELLWEGER SYNDROME;

17-HYDROXYSTEROID DEHYDROGENASES; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA PRIMERS; ENOYL-COA HYDRATASE; EXONS; HUMANS; HYDRO-LYASES; IMMUNOHISTOCHEMISTRY; INTRONS; MULTIENZYME COMPLEXES; MUTAGENESIS; RNA, MESSENGER; SWINE;

EID: 2542508064     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(99)00066-7     Document Type: Conference Paper

References (32)

1. Penning T.M. Molecular endocrinology of hydroxysteroid dehydrogenases. Endocr. Rev. 18:1997;281-305.
2. Zhang Y., Dufort I., Soucy P., Labrie F., Luu-The V. Cloning and expression of human type V 17β-hydroxysteroid dehydrogenase. Proceedings of the 77th Annual Meeting Endocrine Society. 1995;622.
3. Biswas M.G., Russell D.W. Expression cloning and characterization of oxidative 17beta- and 3alpha- hydroxysteroid dehydrogenases from rat and human prostate. J. Biol. Chem. 272:1997;15,959-15,966.
4. Nokelainen P., Peltoketo H., Vihko R., Vihko P. Expression cloning of a novel estrogenic mouse 17 beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase (m17HSD7), previously described as a prolactin receptor-associated protein (PRAP) in rat. Mol. Endocrinol. 12:1998;1048-1059.
5. Formicheva J., Baker M., Anderson E., Lee G.Y., Aziz N. Charakterization of Ke 6, a new 17β-hydroxysteroid dehydrogenase and its expression in gonadal tissues. J. Biol. Chem. 273:1998;22,664-22,671.
6. Adamski J., Normand T., Leenders F., Monte D., Begue A., Stehelin D., Jungblut P.W., de Launoit Y. Molecular cloning of a novel widely expressed human 80 kDa 17β-hydroxysteroid dehydrogenase IV. Biochem. J. 311:1995;437-443.
7. Jörnvall H., Persson B., Krook M., Atrian S., Gozales-Duarte R., Jeffery J., Ghosh D. Short-chain dehydrogenases/reductases (SDR). Biochemistry. 34:1995;6003-6013.
8. Qin Y.M., Poutanen M.H., Helander H.M., Kvist A.P., Siivari K.M., Schmitz W., Conzelmann E., Hellman U., Hiltunen J.K. Peroxisomal multifunctional enzyme of beta-oxidation metabolizing D-3-hydroxyacyl-CoA esters in rat liver: molecular cloning, expression and characterization. Biochem. J. 321:1997;21-28.
9. Corton J.C., Bocos C., Moreno E.S., Merritt A., Marsman D.S., Sausen P.J., Cattley R.C., Gustafsson J.Å. The rat 17β-hydroxysteroid dehydrogenase type IV is a novel peroxisome-proliferator-inducible gene. Molecular Pharmacology. 50:1996;1157-1166.
10. Normand T., Husen B., Leenders F., Pelczar H., Baert J.L., Begue A., Flourens A.C., Adamski J., de Launoit Y. Molecular characterization of mouse 17 beta-hydroxysteroid dehydrogenase IV. J. Steroid Biochem. Mol. Biol. 55:1995;541-548.
11. Leenders F., Adamski J., Husen B., Thole H.H., Jungblut P.W. Molecular cloning and amino acid sequence of the porcine 17β-estradiol dehydrogenase. Eur. J. Biochem. 222:1994;221-227.
12. Kobayashi K., Kobayashi H., Ueda M., Honda Y. Expression of 17 beta-hydroxysteroid dehydrogenase type IV in chick retinal pigment epithelium. Exp. Eye Res. 64:1997;719-726.
13. Caira F., Clemencet M.C., Cherkaoui-Malki M., Dieuaide-Noubhani M., Pacot C., Van Veldhoven P.P., Latruffe N. Differential regulation by a peroxisome proliferator of the different multifunctional proteins in guinea pig: cDNA cloning of the guinea pig D-specific multifunctional protein 2. Biochem. J. 330:1998;1361-1368.
14. Markus M., Husen B., Leenders F., Jungblut P.W., Hall P.F., Adamski J. The organelles containing porcine 17β-hydroxysteroid dehydrogenase are peroxisomes. Eur. J. Cell. Biol. 68:1995;263-267.
15. Leenders F., Tesdorpf J.G., Markus M., Engel T., Seedorf U., Adamski J. Porcine 80 kDa protein reveals intrinsic 17β-hydroxysteroid dehydrogenase, fatty acyl-CoA-hydratase/dehydrogenase and sterol transfer activities. J. Biol. Chem. 271:1996;5438-5442.
16. Dieuaide-Noubhani M., Novikov D., Baumgart E., Vanhooren J.C.T., Fransen M., Goethals M., Vandekerkhove J., Van Veldhoven P.P., Mannaerts G.P. Further characterisation of the peroxisomal 3-hydroxyacyl-CoA dehydrogenase from rat liver. Relationship between different dehydrogenases and evidence that fatty acids and the C27 bile acids di and tri.hydroxycoprostanic acids are metabolized by separate multifunctional proteins. Eur. J. Biochem. 240:1996;660-666.
17. Dieuaide-Noubhani M., Asselberghs S., Mannaerts G.P., Van Veldhoven P.P. Evidence that multifunctional protein 2, and not multifunctional protein 1, is involved in the peroxisomal beta-oxidation of pristanic acid. Biochem. J. 325:1997;367-373.
18. Novikov D., Dieuaide-Noubhani M., Vermeesch J.R., Fournier B., Mannaerts G.P., Van Veldhoven P.P. The human peroxisomal multifunctional protein involved in bile acid synthesis: activity measurement, deficiency in Zellweger syndrome and chromosome mapping. Biochim. Biophys. Acta. 1360:1997;229-240.
19. Qin Y.M., Haapalainen A.M., Conry D., Cuebas D.A., Hiltunen J.K., Novikov D.K. Recombinant 2-enoyl-CoA hydratase derived from rat peroxisomal multifunctional enzyme 2: role of the hydratase reaction in bile acid synthesis. Biochem. J. 328:1997;377-382.
20. Suzuki Y., Jiang L.L., Souri M., Miyazawa S., Fukuda S., Zhang Z., Une M., Shimozawa N., Kondo N., Orii T., Hashimoto T. D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency: a newly identified peroxisomal disorder. Am. J. Hum. Genet. 61:1997;1153-1162.
21. van Grunsven E.G., van Berkel E., Ijlst L., Vreken P., de Klerk J.B.C., Adamski J., Lemonde H., Clayton P.T., Cuebas D.A., Wanders R.J.A. Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: Resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency. Proc. Natl. Acad. Sci. USA. 95:1998;2128-2133.
22. Leenders F., Husen B., Thole H.H., Adamski J. The sequence of porcine 80 kDa 17β-estradiol dehydrogenase reveals similarities to the short chain alcohol dehydrogenase family, to actin binding motifs and to sterol carrier protein 2. Molecular and Cellular Endocrinology. 104:1994;127-131.
23. Husen B., Adamski J., Szendro P.I., Jungblut P.W. Alterations in the subcellular distribution of 17β-estradiol dehydrogenase in porcine endometrial cells over the course of the estrous cycle. Cell & Tissue Research. 278:1994;227-233.
24. Leenders F., Dolez V., Begue A., Möller G., Gloeckner J.C., de Launoit Y., Adamski J. Structure of the gene for the human 17β-hydroxysteroid dehydrogenase type IV. Mammalian Genome. 9:1998;1036-1041.
25. Adamski J., Sierralta W.D., Jungblut P.W. Assignment of estradiol-17β dehydrogenase and of estrone reductase to cytoplasmic structures of porcine endometrium cells. Acta Endocrinologica. 121:1989;161-167.
26. Labrie F. Intracrinology. Mol. Cell Endocrinol. 78:1991;C113-C118.
27. Lazarow P.B., Moser H.W. Disorders of peroxisome biogenesis. Scriver C.R., et al. The Metabolic and Molecular Basis of Inherited Disease. 1995;2287-2316 McGraw-Hill, New York.
28. Wanders R.J.A., Schutgens R.B.H., Barth P.G. Peroxisomal disorders: A review. J. Neuropath. Exp. Neurol. 54:1995;726-739.
29. Leenders F., Prescher G., de Launoit Y., Adamski J. Assignment of human 17β-hydroxysteroid dehydrogenase IV to chromosome 5q2 by fluorescence in situ hybridization. Genomics. 37:1996;403-404.
30. Jiang L.L., Miyazawa S., Hashimoto T. Purification and properties of rat D-3-hydroxyacyl-CoA dehydratase: D-3-hydroxyacyl-CoA dehydratase/(D-3-Hydroxyacyl-CoA dehydrogenase bifunctional protein. J. Biochem. 120:1996;633-641.
31. Palosaari P.M., Hiltunen J.K. Peroxisomal bifunctional protein from rat liver is a trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities. J. Biol. Chem. 265:1990;2446-2449.
32. Osumi T., Ishii N., Hijikata M., Kamijo K., Ozasa H., Furuta S., Miyazawa S., Kondo K., Inoue K., Kagamiyama H., et al. Molecular cloning and nucleotide sequence of the cDNA for rat peroxisomal enoyl-CoA: hydratase-3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme. J. Biol. Chem. 260:1985;8905-8910.