Mitoinhibitory effects of the tumor promoter 2-acetylaminofluorene in rat liver: Loss of E2F-1 and E2F-3 expression and cdk 2 kinase activity in late G1

Journal of Hepatology

Volumn 40, Issue 6, 2004, Pages 957-962

  Ohlson, Lena C E ^a,b   Koroxenidou, Lena ^a,b   Porsch Hällström, Inger ^a  

^a SÖDERTÖRN UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

2 AAF, 2 acetylaminofluorene; 2 acetylaminofluorene; cdk, cyclin dependent kinase; Cell cycle protein; E2F transcription factors; Liver regeneration; PH, partial hepatectomy; pRb, retinoblastoma protein; Retinoblastoma protein; Tumor promoter

Indexed keywords

CYCLIN A; CYCLIN D; CYCLIN DEPENDENT KINASE 2; HISTONE H1; N (2 FLUORENYL)ACETAMIDE; PROTEIN P107; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F3;

ANIMAL TISSUE; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL NUCLEUS; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; ENZYME ASSAY; ENZYME INHIBITION; LIVER; MALE; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; TUMOR PROMOTION; WESTERN BLOTTING;

2-ACETYLAMINOFLUORENE; ANIMALS; CARCINOGENS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASES; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; E2F3 TRANSCRIPTION FACTOR; G1 PHASE; GENE EXPRESSION REGULATION; HISTONES; LIVER; MALE; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; RATS; RATS, WISTAR; TRANSCRIPTION FACTORS;

EID: 2542498042     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(04)00102-3     Document Type: Article

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