Endotracheal tubes coated with antiseptics decrease bacterial colonization of the ventilator circuits, lungs, and endotracheal tube

Anesthesiology

Volumn 100, Issue 6, 2004, Pages 1446-1456

  Berra, Lorenzo ^a   De Marchi, Lorenzo ^a   Yu, Zu Xi ^b   Laquerriere, Patrice ^c   Baccarelli, Andrea ^c   Kolobow, Theodor ^a,b  

^a Pulmon Critical Care Med Branch   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CHLORHEXIDINE; POLYURETHAN; SULFADIAZINE SILVER;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIUM CULTURE; BIOFILM; BRONCHUS; COLONY FORMING UNIT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOTRACHEAL INTUBATION; ENDOTRACHEAL TUBE; FEMALE; FILTER; LASER MICROSCOPY; LUNG; LUNG PARENCHYMA; MATERIAL COATING; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; SHEEP; TRACHEA; VENTILATOR;

ANIMALS; CHLORHEXIDINE; COLONY COUNT, MICROBIAL; DISINFECTANTS; EQUIPMENT CONTAMINATION; FEMALE; INTUBATION, INTRATRACHEAL; LUNG; SHEEP; SILVER SULFADIAZINE; VENTILATORS, MECHANICAL;

EID: 2542496745     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200406000-00017     Document Type: Article

References (49)

1. Vincent JL, Bihari DJ, Suter PM, Bruining HA, White J, Nicolas-Chanoin MH, Wolff M, Spencer RC, Hemmer M: The prevalence of nosocomial infection in intensive care units in Europe: Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA 1995; 274:639-44
2. Richards MJ, Edwards JR, Culver DH, Gaynes RP: Nosocomial infections in medical intensive care units in the United States: National Nosocomial Infections Surveillance System. Crit Care Med 1999; 27:887-92
3. Chastre J, Fagon JY: Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002; 165:867-903
4. Wallace WC, Cinat ME, Nastanski F, Gornick WB, Wilson SE: New epidemiology for postoperative nosocomial infections. Am Surg 2000; 66:874-8
5. Kozlow JH, Berenholtz SM, Garrett E, Dorman T, Pronovost PJ: Epidemiology and impact of aspiration pneumonia in patients undergoing surgery in Maryland, 1999-2000. Crit Care Med 2003; 31:1930-7
6. Montravers P, Veber B, Auboyer C, Dupont H, Gauzit R, Korinek AM, Malledant Y, Martin C, Moine P, Pourriat JL: Diagnostic and therapeutic management of nosocomial pneumonia in surgical patients: Results of the Eole study. Crit Care Med 2002; 30:368-75
7. Craven DE, Goularte TA, Make BJ: Contaminated condensate in mechanical ventilator circuits: A risk factor for nosocomial pneumonia? Am Rev Respir Dis 1984; 129:625-8
8. Adair CG, Gorman SP, Feron BM, Byers LM, Jones DS, Goldsmith CE, Moore JE, Kerr JR, Curran MD, Hogg G, Webb CH, McCarthy GJ, Milligan KR: Implications of endotracheal tube biofilm for ventilator-associated pneumonia. Intensive Care Med 1999; 25:1072-6
9. Sottile FD, Marrie TJ, Prough DS, Hobgood CD, Gower DJ, Webb LX, Costerton JW, Gristina AG: Nosocomial pulmonary infection: Possible etiologic significance of bacterial adhesion to endotracheal tubes. Crit Care Med 1986; 14:265-70
10. Inglis TJ, Millar MR, Jones JG, Robinson DA: Tracheal tube biofilm as a source of bacterial colonization of the lung. J Clin Microbiol 1989; 27:2014-8
11. Cash HA, Woods DE, McCullough B, Johanson WG Jr, Bass JA: A rat model of chronic respiratory infection with Pseudomonas aeruginosa. Am Rev Respir Dis 1979; 119:453-9
12. Costerton JW, Stewart PS, Greenberg EP: Bacterial biofilms: A common cause of persistent infections. Science 1999; 284:1318-22
13. Potera C: Forging a link between biofilms and disease. Science 1999; 283:1837, 1839
14. Lyte M, Freestone PP, Neal CP, Olson BA, Haigh RD, Bayston R, Williams PH: Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes. Lancet 2003; 361:130-5
15. Davies DG, Parsek MR, Pearson JP, Iglewski BH, Costerton JW, Greenberg EP: The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science 1998; 280:295-8
16. Craven DE, Connolly MG Jr, Lichtenberg DA, Primeau PJ, McCabe WR: Contamination of mechanical ventilators with tubing changes every 24 or 48 hours. N Engl J Med 1982; 306:1505-9
17. Christopher KL, Saravolatz LD, Bush TL, Conway WA: The potential role of respiratory therapy equipment in cross infection: A study using a canine model for pneumonia. Am Rev Respir Dis 1983; 128:271-5
18. Olson ME, Harmon BG, and Kollef MH: Silver-coated endotracheal tubes associated with reduced bacterial burden in the lungs of mechanically ventilated dogs. Chest 2002; 121:863-70
19. Jones DS, McMeel S, Adair CG, Gorman SP: Characterization and evaluation of novel surfactant bacterial anti-adherent coatings for endotracheal tubes designed for the prevention of ventilator-associated pneumonia. J Pharm Pharmacol 2003; 55(1):43-52
20. Fox CL Jr, Modak SM, Sampath LA: Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same. United States of America, May 28, 1991, Patent No. 5019096
21. DeRiso AJ, Ladowski JS, Dillon TA, Justice JW, Peterson AC: Chlorhexidine gluconate 0.12% oral rinse reduces the incidence of total nosocomial respiratory infection and nonprophylactic systemic antibiotic use in patients undergoing heart surgery. Chest 1996; 109:1556-61
22. Quesnel LB, Al Najjar AR, Buddhavudhikrai P: Synergism between chlorhexidine and sulphadiazine. J Appl Bacteriol 1978; 45:397-405
23. George N, Faoagali J, Muller M: Silvazine (silver sulfadiazine and chlorhexidine) activity against 200 clinical isolates. Burns 1997; 23:493-5
24. Darouiche RO, Raad II, Heard SO, Thornby JI, Wenker OC, Gabrielli A, Berg J, Khardori N, Hanna H, Hachem R, Harris RL, Mayhall G: A comparison of two antimicrobial-impregnated central venous catheters. Catheter Study Group. N Engl J Med 1999; 340:1-8
25. Guide for the Care and Use of Laboratory Animals. Washington, DC, National Academy Press, 1996, pp 1-80
26. Panigada M, Berra L, Greco G, Stylianou M, Kolobow T: Bacterial colonization of the respiratory tract following tracheal intubation-effect of gravity: An experimental study. Crit Care Med 2003; 31:729-37
27. Fisher LD, Van Belle G: The Wilcoxon (Mann-Whitney) two-sample test, Biostatistics. New York, 1993, pp 315-9
28. Fisher LD, Van Belle G: Fisher's exact test, Biostatistics. New York, 1993, pp 185-6
29. Girou E, Schortgen F, Delclaux C, Brun-Buisson C, Blot F, Lefort Y, Lemaire F, Brochard L: Association of noninvasive ventilation with nosocomial infections and survival in critically ill patients. JAMA 2000; 284:2361-7
30. Langer M, Cigada M, Mandelli M, Mosconi P, Tognoni G: Early onset pneumonia: A multicenter study in intensive care units. Intensive Care Med 1987; 13:342-6
31. Fink JB, Krause SA, Barrett L, Schaaff D, Alex CG: Extending ventilator circuit change interval beyond 2 days reduces the likelihood of ventilator-associated pneumonia. Chest 1998; 113:405-11
32. O'Toole GA: Microbiology: A resistance switch. Nature 2002; 416:695-6
33. Stewart PS, Costerton JW: Antibiotic resistance of bacteria in biofilms. Lancet 2001; 358:135-8
34. Prince AS: Biofilms, antimicrobial resistance, and airway infection. N Engl J Med 2002; 347:1110-1
35. Suci PA, Mittelman MW, Yu FP, Geesey GG: Investigation of ciprofloxacin penetration into Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother 1994; 38:2125-33
36. Duguid IG, Evans E, Brown MR, Gilbert P: Effect of biofilm culture upon the susceptibility of Staphylococcus epidermidis to tobramycin. J Antimicrob Chemother 1992; 30:803-10
37. Tuomanen E, Cozens R, Tosch W, Zak O, Tomasz A: The rate of killing of Escherichia coli by beta-lactam antibiotics is strictly proportional to the rate of bacterial growth. J Gen Microbiol 1986; 132(part 5):1297-304
38. Whiteley M, Bangera MG, Bumgarner RE, Parsek MR, Teitzel GM, Lory S, Greenberg EP: Gene expression in Pseudomonas aeruginosa biofilms. Nature 2001; 413:860-4
39. Steinberger RE, Allen AR, Hansa HG, Holden PA: Elongation correlates with nutrient deprivation in Pseudomonas aeruginosa-unsaturates biofilms. Microb Ecol 2002; 43:416-23
40. Drenkard E, Ausubel FM: Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation. Nature 2002; 416:740-3
41. Tack KJ, Sabath LD: Increased minimum inhibitory concentrations with anaerobiasis for tobramycin, gentamicin, and amikacin, compared to latamoxef, piperacillin, chloramphenicol, and clindamycin. Chemotherapy 1985; 31:204-10
42. Wilkes AR, Benbough JE, Speight SE, Harmer M: The bacterial and viral filtration performance of breathing system filters. Anaesthesia 2000; 55:458-65
43. Craven DE, Steger KA: Epidemiology of nosocomial pneumonia: New perspectives on an old disease. Chest 1995; 108(suppl):1S-16S
44. Torres A, Serra-Batlles J, Ros E, Piera C, Puig de la Bellacasa J, Cobos A, Lomena F, Rodriguez-Roisin R: Pulmonary aspiration of gastric contents in patients receiving mechanical ventilation: The effect of body position. Ann Intern Med 1992; 116:540-3
45. Russell AD, Hugo WB: Antimicrobial activity and action of silver. Prog Med Chem 1994; 31:351-70
46. Sampath LA, Saborio DV, Yaron I, Modak S: Safety and efficacy of an improved antiseptic catheter impregnated intraluminally with chlorhexidine. J Infus Nurs 2001; 24:395-403
47. Karchmer TB, Giannetta ET, Muto CA, Strain BA, Farr BM: A randomized crossover study of silver-coated urinary catheters in hospitalized patients. Arch Intern Med 2000; 160:3294-8
48. Snelling CF, Inman RJ, Germann E, Boyle JC, Foley B, Kester DA, Fitzpatrick DJ, Warren RJ, Courtemanche AD: Comparison of silver sulfadiazine 1% with chlorhexidine digluconate 0.2% to silver sulfadiazine 1% alone in the prophylactic topical antibactecial treatment of burns. J Burn Care Rehabil 1991; 12:13-8
49. Sampath LA, Tambe SM, Modak SM: In vitro and in vivo efficacy of catheters impregnated with antiseptics or antibiotics: Evaluation of the risk of bacterial resistance to the antimicrobials in the catheters. Infect Control Hosp Epidemiol 2001; 22:640-6