Synthesis and evaluation of ATP-binding site directed potential inhibitors of nucleoside triphosphatases/helicases and polymerases of hepatitis C and other selected Flaviviridae viruses

Antiviral Chemistry and Chemotherapy

Volumn 15, Issue 1, 2004, Pages 35-42

  Bretner, Maria ^a   Schalinski, Sarah ^b   Haag, Annemarie ^b   Lang, Melanie ^b   Schmitz, Herbert ^b   Baier, Andrea ^b   Behrens, Sven E ^c   Kulikowski, Tadeusz ^a   Borowski, Peter ^b  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Flaviviridae; HCV; Inhibitors; NTPase helicase; RNA polymerase

Indexed keywords

5' O (4 FLUOROSULFONYLBENZOYL)ADENOSINE; 5' O (4 FLUOROSULFONYLBENZOYL)GUANOSINE; 5' O (4 FLUOROSULFONYLBENZOYL)INOSINE; 5' O (4 FLUOROSULFONYLBENZOYL)RIBAVIRIN; DNA POLYMERASE; ENZYME INHIBITOR; ESTER DERIVATIVE; GUANOSINE TRIPHOSPHATE; HELICASE; NUCLEOSIDE TRIPHOSPHATASE; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

ACYLATION; ARTICLE; BINDING SITE; DENGUE VIRUS; DNA DENATURATION; DRUG BINDING; DRUG EFFECT; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; FLAVIVIRUS; HEPATITIS C VIRUS; IC 50; JAPANESE ENCEPHALITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; WEST NILE FLAVIVIRUS;

EID: 2542481860     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632020401500104     Document Type: Article

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