Expression of cell proliferating genes in patients with non-small cell lung cancer by immunohistochemistry and cDNA profiling

Oncology Reports

Volumn 13, Issue 5, 2005, Pages 837-846

  Mao, Yongrong ^a   Wu, Jainping ^a   Skog, Sven ^b   Eriksson, Staffan ^c   Zhao, Yiwei ^d   Zhou, Ji ^d   He, Qimin ^b  

^a HUBEI CANCER HOSPITAL   (China)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^d Sino Swed Tong Kang Biological Technology Inc   (China)

Author keywords

cDNA array; Histochemical staining; Ki 67; Lung adenocarcinoma; Lung squamous cell carcinoma; Thymidine kinase 1; Tumor stage and grade

Indexed keywords

COMPLEMENTARY DNA; KI 67 ANTIGEN; PEPTIDE FRAGMENT; THYMIDINE KINASE; THYMIDINE KINASE 1;

ADENOMA; AMINO ACID SEQUENCE; ARTICLE; CANCER STAGING; CELL DIVISION; CHEMISTRY; DNA FINGERPRINTING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MOLECULAR GENETICS; PATHOLOGY; SQUAMOUS CELL CARCINOMA;

ADENOMA; AMINO ACID SEQUENCE; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; DNA FINGERPRINTING; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KI-67 ANTIGEN; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; NEOPLASM STAGING; PEPTIDE FRAGMENTS; THYMIDINE KINASE;

EID: 25144508220     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.13.5.837     Document Type: Article

References (39)

1. Sherr CJ: Cancer cell cycle. Science 274: 1672-1677, 1996.
2. Yoshida T, Tanaka S, Mogi A, Shitara Y and Kuwano H: The clinical significance of cyclin B1 and Weel expression in non-small-cell lung cancer. Ann Oncol 15: 252-256, 2004. (Pubitemid 38262624)
3. Scholzen T and Gerdes J: The Ki-67 protein: from the known and the unknown. J Cell Physiol 182: 311-322, 2000. (Pubitemid 30054364)
4. Mehdi SA, Tatum AH, Newman NB, Gamble GP, Etzell JE, Weidner N, Kern JA, Sorscher SM, Kohman LJ and Graziano SL: Prognostic markers in resected stage I and II non small-cell lung cancer: an analysis of 260 patients with 5 year follow-up. Clin Lung Cancer 1:59-69, 1999.
5. Masuya D, Huang C, Liu D, Nakashima T, Kameyama K, Haba R, Ueno M and Yokomise H: The tumour-stromal interaction between intratumoral c-Met and stromal hepatocyte growth factor associated with tumour growth and prognosis in non-small-cell lungcancerpatients. Br J Cancer 19: 1555-1562, 2004. (Pubitemid 38648238)
6. Haga Y, Hiroshima K, Iyoda A, Shibuya K, Shimamura F, Iizasa T, Fujisawa T and Ohwada H: Ki-67 expression and prognosis for smokers with resected stage I non-small-cell lung cancer. Ann Thorac Surg 75: 1727-1733, 2003.
7. Toledo G, Sola JJ, Lozano MD, Soria E and Pardo J: Loss of FHIT protein expression is related to high proliferation, low apoptosis and worse prognosis in non-small-cell lung cancer. Mod Pathol 17: 440-448, 2004. (Pubitemid 41646599)
8. Vicent S, Lopez-Picazo JM, Toledo G, Lozano MD, Torre W, Garcia-Corchon C, Quero C, Soria JC, Martin-Algarra S, Manzano RG and Montuenga LM: ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours. Br J Cancer 8: 1047-1052, 2004. (Pubitemid 38495827)
9. Hilbe W, Dirnhofer S, Oberwasserlechner F, Eisterer W, Ammann K, Schmid T, Hilbe G, Thaler J and Woll E: Immunohistochemical typing of non-small cell lung cancer on cryostat sections: correlation with clinical parameters and prognosis. J Clin Pathol 56: 736-741, 2003. (Pubitemid 37243931)
10. Pelosi G, Pasini F, Sonzogni A, Maffini F, Maisonneuve P, Iannucci A, Terzi A, De Manzoni G, Bresaola E and Viale G. Prognostic implications of neuroendocrine differentiation and hormone production in patients with Stage I nonsmall cell lung carcinoma. Cancer 97: 2487-2497, 2003. (Pubitemid 36542488)
11. Politi EN, Lazaris AC, Kavantzas N and Koutselini H: Comparison between morphometry and immunostaining of malignant cells in non-small cell lung cancer. Anal Quant Cytol Histol 25: 169-176, 2003. (Pubitemid 36705515)
12. Pelosi G, Fraggetta F, Nappi O, Pastorino U, Maisonneuve P, Pasini F, Iannucci A, Solli P, Musavinasab HS, De Manzoni G, Terzi A and Viale G: Pleomorphic carcinomas of the lung show a selective distribution of gene products involved in cell differentiation, cell cycle control, tumor growth, and tumor cell motility: a clinicopathologic and immunohistochemical study of 31 cases. Am J Surg Pathol 27: 1203-1215, 2003. (Pubitemid 37040582)
13. He Q, Mao RY and Wu JP: Immunohistochemical expression of thymidine kinase in patients with breast carcinoma. In: Immunohistochemical and In Situ Hybridisation of Human Carcinomas. Hayat MA (ed). Elsevier Science/Academic, New York, pp463-489, 2004.
14. He Q, Mao YR, Wu JP, Decker C, Merza M, Wang N, Eriksson S, Castro J and Skog S: Cytosolic thymidine kinase is a specific histopathologic tumour marker for breast carcinomas. Int J Oncol 25: 945-953, 2004.
15. Mao YR, Wu JP, Wang N, He JX, Wu CJ, He Q and Skog S: Comparison study: immunohistochemical detection of cytosolic thymidine kinase and proliferating cell nuclear antigen in breast cancer. Cancer Invest 20: 922-931, 2002. (Pubitemid 35315926)
16. Wang N, He Q, Skog S, Eriksson S and Tribukait B: Investigation on cell proliferation with a new antibody against thymidine kinase 1. Anal Cell Pathol 23: 11-19, 2001. (Pubitemid 34014656)
17. Wu JP, Mao YR, He LX, Wang N, Wu CJ, He Q and Skog S: Comparison study on the expression of cytosolic thymidine kinase and proliferating cell nuclear antigen in colorectal carcinoma. Anticancer Res 6: 4867-4872, 2000.
18. Wu CJ, Yang RJ, Zhou J, Bao S, Zou L, Mao YR and He Q: Production and characterisation of a novel chicken IgY antibody raised against C-terminal peptide from human thymidine kinase 1. J Immunol Methods 277: 157-169, 2003. (Pubitemid 36694382)
19. Sobin LH and Wittekind C: UICC TNM classification of malignant tumours. 5th edition. Wiley-Liss, New York, pp91-97, 1997.
20. He Q, Wang N, Skog S, Eriksson S and Tribukait B: Characterization of a peptide antibody against a C-terminal part of human and mouse cytosolic thymidine kinase, which is a marker for cell proliferation. Eur J Cell Biol 70: 117-124, 1996. (Pubitemid 26177210)
21. Kauffman MG and Kelly TJ: Cell cycle regulation of thymidine kinase: Residues near the carboxyl terminus are essential for the specific degradation of the enzyme at mitosis. Mol Cell Biol 11: 2538-2546, 1991. (Pubitemid 21895633)
22. He Q, Zou L, Zhang PG, Liu JT, Skog S and Fonander T: The clinical significance of thymidine kinase 1 measurement in serum of breast cancer patients using anti-TKl antibody. J Biol Markers 15: 139-146, 2000. (Pubitemid 30389361)
23. Zou L, Zhang PG, Zou S, Li Y and He Q: The half-life of cytosolic thymidine kinase in serum by ECL dot blot: a potential marker for monitoring the response to surgery of patients with gastric cancer. Int J Biol Markers 17: 135-140, 2002. (Pubitemid 34873800)
24. Elsevier SM, Kucherlapati RS, Nichols EA, Creagan RP, Giles RE, Ruddle AFH, Willeeke K and McDougall JK: Assignment of the gene for galactokinase to human chromosome 17 and its regional localization to band q 21-22. Nature 251: 633-635, 1974.
25. Willeeke K, Reber T, Kucherlapati RS and Ruddle FH: Human mitochondrial thymidine kinase is coded for by a gene on chromosome 16 of the nucleus. Somat Cell Mol Genet: 237-245, 1977. (Pubitemid 8160573)
26. Ke PY and Chang ZF: Mitotic degradation of human thymidine kinase 1 is dependent on the anaphase-promoting complex/ cyclosome-CDH1-mediated pathway. Mol Cell Biol 24: 514-526, 2004.
27. Sherley JL and Kelly TJ: Regulation of human thymidine kinase during the cell cycle. J Biol Chem 26: 8350-8358, 1998.
28. Sherley JL and Kelly TJ: Human cytosolic thymidine kinase. Purification and physical characterization of the enzyme from HeLa cells. J Biol Chem 263: 375-383, 1998.
29. Anér ES and Eriksson S: Mammalian deoxynucleoside kinase. Pharmac Ther 67: 155-186, 1995.
30. He Q, Skog S and Tribukait B: Cell cycle related studies on thymidine kinase and its isoenzymes in Ehrlich ascites tumours. Cell Prolif 24: 3-14, 1991.
31. Munch-Petersen B, Cloos L, Jensen HK and Tyrsted G: Human thymidine kinase 1. Regulation in normal and malignant cells. Adv Enzyme Regul 35: 69-89, 1995.
32. Brown RW, Allred CD, Clark GM, Osborne CK and Hilsenbeck SG: Prognostic value of Ki-67 compared to S-phase fraction in axillary node-negative breast cancer. Clin Cancer Res 2: 585-592, 1996. (Pubitemid 26099178)
33. Mate JL, Ariza A, Aracil C, Lopez D, Isamat M, Perez-Piteira J and Navas-PaACios JJ: Cyclin D1 overexpression in non-small cell lung carcinoma: correlation with Ki-67 labeling index and poor cytoplasmic differentiation. J Pathol 180: 395-399, 1996.
34. Iloachim EE, Katsanos KH, Michael MC, Tsianos EV, and Agnantis NJ: Immunohistochemical expression of cyclin D1, cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease: correlation with other cell-cycle-related proteins (Rb, p53, Ki-67 and PCNA) and clinicopathological features. Int J Colorectal Dis 19: 325-333, 2004. (Pubitemid 38868298)
35. WAF1/CIP1expression in primary lung adenocarcinomas: heterogeneous expression in tumor tissues and correlation with p53 expression and proliferative activities. Carcinogenesis 19: 1755-1761, 1998.
36. Amirghofran Z, Monabati A and Gholijani N: Androgen receptor expression in relation to apoptosis and the expression of cell cycle related proteins in prostate cancer. Pathol Oncol Res 10: 37-41, 2004. (Pubitemid 38514668)
37. 1NK4aand other cell cycle regulator and senescence associated genes in aging human kidney. Kidney Int 65: 510-520, 2004.
38. Kikuchi T, Daigo Y, Katagiri T, Tsunoda T, Okada K, Kakiuchi S, Zembutsu H, Furukawa Y, Kawamura M, Kobayashi K, Imai K and Nakamura Y: Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs. Oncogene 122: 2192-2205, 2003. (Pubitemid 36539569)
39. Skog S, He Q, Khoshnoud R, Fornander T and Rutqvist LE: Gene expression in an estrogen receptor-negative (MDA-231) versus an estrogenreceptor-positive (MCF-7) breast tumor cell line according to cDNA micro-array. Tumor Biol 25: 41-47, 2004.