Zinc finger protein 267 is up-regulated during the activation process of human hepatic stellate cells and functions as a negative transcriptional regulator of MMP-10

Biochemical and Biophysical Research Communications

Volumn 335, Issue 1, 2005, Pages 87-96

  Schnabl, Bernd ^a,c   Hu, Kanghong ^a   Mühlbauer, Marcus ^a   Hellerbrand, Claus ^a   Stefanovic, Branko ^b   Brenner, David A ^c   Schölmerich, Jürgen ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c College of Physicians and Surgeons ^*  (United States)

Author keywords

Collagen; Kruppel associated box; Kruppel like zinc finger proteins; Liver fibrosis; Transcriptional repressor

Indexed keywords

CYAN FLUORESCENT PROTEIN; HYBRID PROTEIN; MESSENGER RNA; STROMELYSIN 2; TRANSCRIPTION FACTOR GAL4; ZINC FINGER PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ACTIVATION; CELL NUCLEUS; CONTROLLED STUDY; DNA BINDING; DNA MICROARRAY; EMBRYO; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIVER CELL; LIVER CIRRHOSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REPORTER GENE; RIBONUCLEASE PROTECTION ASSAY; STELLATE CELL; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION;

CELL NUCLEUS; CELLS, CULTURED; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; HEPATOCYTES; HISTONE DEACETYLASES; HUMANS; LIVER CIRRHOSIS; MATRIX METALLOPROTEINASE 10; METALLOENDOPEPTIDASES; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 25144468006     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.07.043     Document Type: Article

References (47)

1. S.L. Friedman Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury J. Biol. Chem. 275 2000 2247 2250
2. A.M. de Leeuw, S.P. McCarthy, A. Geerts, and D.L. Knook Purified rat liver fat-storing cells in culture divide and contain collagen Hepatology 4 1984 392 403
3. M. Parola, G. Robino, F. Marra, M. Pinzani, G. Bellomo, G. Leonarduzzi, P. Chiarugi, S. Camandola, G. Poli, G. Waeg, P. Gentilini, and M.U. Dianzani HNE interacts directly with JNK isoforms in human hepatic stellate cells J. Clin. Invest. 102 1998 1942 1950
4. B. Schnabl, C.A. Bradham, B.L. Bennett, A.M. Manning, B. Stefanovic, and D.A. Brenner TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells Hepatology 34 2001 953 963
5. C. Hellerbrand, C. Jobin, L.L. Licato, R.B. Sartor, D.A. Brenner, Cytokines induce NF-kappaB in activated but not in quiescent rat hepatic stellate cells, Am. J. Physiol. 275 (1998) G269-278.
6. C. Hellerbrand, C. Jobin, Y. Iimuro, L. Licato, R.B. Sartor, and D.A. Brenner Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor Hepatology 27 1998 1285 1295
7. P. Greenwel, J.A. Dominguez-Rosales, G. Mavi, A.M. Rivas-Estilla, and M. Rojkind Hydrogen peroxide: a link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells Hepatology 31 2000 109 116
8. E.R. Garcia-Trevijano, M.J. Iraburu, L. Fontana, J.A. Dominguez-Rosales, A. Auster, A. Covarrubias-Pinedo, and M. Rojkind Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells Hepatology 29 1999 960 970
9. T. Miyahara, L. Schrum, R. Rippe, S. Xiong, H.F. Yee Jr., K. Motomura, F.A. Anania, T.M. Willson, and H. Tsukamoto Peroxisome proliferator-activated receptors and hepatic stellate cell activation J. Biol. Chem. 275 2000 35715 35722
10. F. Marra, E. Efsen, R.G. Romanelli, A. Caligiuri, S. Pastacaldi, G. Batignani, A. Bonacchi, R. Caporale, G. Laffi, M. Pinzani, and P. Gentilini Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells Gastroenterology 119 2000 466 478
11. V. Ratziu, A. Lalazar, L. Wong, Q. Dang, C. Collins, E. Shaulian, S. Jensen, and S.L. Friedman Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis Proc. Natl. Acad. Sci. USA 95 1998 9500 9505
12. A. Chen, and B.H. Davis The DNA binding protein BTEB mediates acetaldehyde-induced, jun N-terminal kinase-dependent alphaI(I) collagen gene expression in rat hepatic stellate cells Mol. Cell. Biol. 20 2000 2818 2826
13. R.A. Rippe, G. Almounajed, and D.A. Brenner Sp1 binding activity increases in activated Ito cells Hepatology 22 1995 241 251
14. T. Collins, J.R. Stone, and A.J. Williams All in the family: the BTB/POZ, KRAB, and SCAN domains Mol. Cell. Biol. 21 2001 3609 3615
15. E.J. Bellefroid, D.A. Poncelet, P.J. Lecocq, O. Revelant, and J.A. Martial The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins Proc. Natl. Acad. Sci. USA 88 1991 3608 3612
16. J.F. Margolin, J.R. Friedman, W.K. Meyer, H. Vissing, H.J. Thiesen, and F.J. Rauscher 3rd Kruppel-associated boxes are potent transcriptional repression domains Proc. Natl. Acad. Sci. USA 91 1994 4509 4513
17. R. Witzgall, E. O'Leary, A. Leaf, D. Onaldi, and J.V. Bonventre The Kruppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression Proc. Natl. Acad. Sci. USA 91 1994 4514 4518
18. M. Abrink, M. Aveskogh, and L. Hellman Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937 DNA Cell Biol. 14 1995 125 136
19. U. Schafer, A. Schneider, and E. Neugebauer Identification of a nitric oxide-regulated zinc finger containing transcription factor using motif-directed differential display Biochim. Biophys. Acta 1494 2000 269 276
20. M. Zariwala, J. Liu, and Y. Xiong Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins Oncogene 17 1998 2787 2798
21. L.V. Madrid, C.Y. Wang, D.C. Guttridge, A.J. Schottelius, A.S. Baldwin Jr., and M.W. Mayo Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB Mol. Cell. Biol. 20 2000 1626 1638
22. B. Schnabl, Y.H. Choi, J.C. Olsen, C.H. Hagedorn, and D.A. Brenner Immortal activated human hepatic stellate cells generated by ectopic telomerase expression Lab. Invest. 82 2002 323 333
23. B. Schnabl, C.A. Purbeck, Y.H. Choi, C.H. Hagedorn, and D.A. Brenner Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype Hepatology 37 2003 653 664
24. B. Stefanovic, B. Schnabl, and D.A. Brenner Inhibition of collagen alpha 1(I) expression by the 5′ stem-loop as a molecular decoy J. Biol. Chem. 277 2002 18229 18237
25. B. Schnabl, Y.O. Kweon, J.P. Frederick, X.F. Wang, R.A. Rippe, and D.A. Brenner The role of Smad3 in mediating mouse hepatic stellate cell activation Hepatology 34 2001 89 100
26. M. Muhlbauer, A.K. Bosserhoff, A. Hartmann, W.E. Thasler, T.S. Weiss, H. Herfarth, G. Lock, J. Scholmerich, and C. Hellerbrand A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease Gastroenterology 125 2003 1085 1093
27. R. Borghi, R. Vene, G. Arena, D. Schubert, A. Albini, and F. Tosetti Transient modulation of cytoplasmic and nuclear retinoid receptors expression in differentiating human teratocarcinoma NT2 cells J. Neurochem. 84 2003 94 104
28. N.H. Cho, K.P. Hong, S.H. Hong, S. Kang, K.Y. Chung, and S.H. Cho MMP expression profiling in recurred stage IB lung cancer Oncogene 23 2004 845 851
29. B. Schnabl, Y.H. Choi, C.H. Hagedorn, R. Bataller, DNA microarrays, data mining: from liver tissue and from cultured cells to study liver fibrogenesis, Methods Mol. Med. (2005) (in press).
30. K. Hu, M. Fink, M. Froh, E. Gabele, C. Hellerbrand, M. Muhlbauer, R. Wiest, J. Scholmerich, and B. Schnabl Characterization of the human zinc finger protein 267 promoter: essential role of nuclear factor Y Biochim. Biophys. Acta 1729 2005 14 23
31. 2+ pump Serca2b and is necessary for collagen type I synthesis Mol. Cell. Biol. 24 2004 1758 1768
32. S. Lepreux, P. Bioulac-Sage, G. Gabbiani, V. Sapin, C. Housset, J. Rosenbaum, C. Balabaud, and A. Desmouliere Cellular retinol-binding protein-1 expression in normal and fibrotic/cirrhotic human liver: different patterns of expression in hepatic stellate cells and (myo)fibroblast subpopulations J. Hepatol. 40 2004 774 780
33. D.C. Schultz, J.R. Friedman, and F.J. Rauscher 3rd Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD Genes Dev. 15 2001 428 443
34. J.R. Friedman, W.J. Fredericks, D.E. Jensen, D.W. Speicher, X.P. Huang, E.G. Neilson, and F.J. Rauscher 3rd KAP-1, a novel corepressor for the highly conserved KRAB repression domain Genes Dev. 10 1996 2067 2078
35. S.S. Kim, Y.M. Chen, E. O'Leary, R. Witzgall, M. Vidal, and J.V. Bonventre A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins Proc. Natl. Acad. Sci. USA 93 1996 15299 15304
36. P. Moosmann, O. Georgiev, B. Le Douarin, J.P. Bourquin, and W. Schaffner Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1 Nucleic Acids Res. 24 1996 4859 4867
37. R. Urrutia KRAB-containing zinc-finger repressor proteins Genome Biol. 4 2003 231
38. P.A. Marks, T. Miller, and V.M. Richon Histone deacetylases Curr. Opin. Pharmacol. 3 2003 344 351
39. D.C. Rockey Hepatic blood flow regulation by stellate cells in normal and injured liver Semin. Liver Dis. 21 2001 337 349
40. D. Schuppan, M. Ruehl, R. Somasundaram, and E.G. Hahn Matrix as a modulator of hepatic fibrogenesis Semin. Liver Dis. 21 2001 351 372
41. S.K. Vyas, H. Leyland, J. Gentry, and M.J. Arthur Rat hepatic lipocytes synthesize and secrete transin (stromelysin) in early primary culture Gastroenterology 109 1995 889 898
42. J.P. Iredale, S. Goddard, G. Murphy, R.C. Benyon, and M.J. Arthur Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes Clin. Sci. (Lond.) 89 1995 75 81
43. R.C. Benyon, and M.J. Arthur Extracellular matrix degradation and the role of hepatic stellate cells Semin. Liver Dis. 21 2001 373 384
44. T. Knittel, M. Mehde, A. Grundmann, B. Saile, J.G. Scharf, and G. Ramadori Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the rat Histochem. Cell. Biol. 113 2000 443 453
45. J.P. Iredale, R.C. Benyon, J. Pickering, M. McCullen, M. Northrop, S. Pawley, C. Hovell, and M.J. Arthur Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors J. Clin. Invest. 102 1998 538 549
46. M.D. Sternlicht, and Z. Werb How matrix metalloproteinases regulate cell behavior Annu. Rev. Cell. Dev. Biol. 17 2001 463 516
47. M. Madlener, C. Mauch, W. Conca, M. Brauchle, W.C. Parks, and S. Werner Regulation of the expression of stromelysin-2 by growth factors in keratinocytes: implications for normal and impaired wound healing Biochem. J. 320 1996 659 664