UV induced responses of the human epidermal IGF system: Impaired anti-apoptotic effects of IGF-I in HaCaT keratinocytes

Growth Factors

Volumn 23, Issue 2, 2005, Pages 151-159

  Thumiger, Susan P ^a   Adams, Timothy E ^b   Werther, George A ^a   Wraight, Christopher J ^a,c   Edmondson, Stephanie R ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b CSIRO   (Australia)

^c Antisense Therepeutics Ltd   (Australia)

Author keywords

Epidermis; IGF binding protein 3 (IGFBP 3); IGF type I receptor (IGF IR); Insulin like growth factor (IGF); Keratinocyte; UV irradiation

Indexed keywords

MESSENGER RNA; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR; LIGAND; TYROSINE;

APOPTOSIS; ARTICLE; CELL ACTIVITY; CELL CULTURE; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; EPIDERMIS; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOREACTIVITY; KERATINOCYTE; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ULTRAVIOLET B RADIATION; WESTERN BLOTTING; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; RADIATION EXPOSURE; TIME; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; EPIDERMIS; HOMEOSTASIS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; KERATINOCYTES; LIGANDS; PHOSPHORYLATION; RECEPTORS, SOMATOMEDIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TYROSINE; ULTRAVIOLET RAYS;

EID: 24944590114     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.1080/08977190500153680     Document Type: Article

References (50)

1. Adams, TE, Epa, VC, Garrett, TP, Ward, CW. Structure and function of the type 1 insulin-like growth factor receptor Cell Mol Life Sci, 2000; 57: 1050-1093
2. Angelloz-Nicoud, P, Lalou, C, Binoux, M. Prostate carcinoma (PC-3) cell proliferation is stimulated by the 22-25-kDa proteolytic fragment (1-160) and inhibited by the 16-kDa fragment (1-95) of recombinant human insulin-like growth factor binding protein-3 Growth Horm IGF Res, 1998; 8: 71-75
3. Batch, JA, Mercuri, FA, Edmondson, SR, Werther, GA. Localization of messenger ribonucleic acid for insulin-like growth factor-binding proteins in human skin by in situ hybridization J Clin Endocrinol Metab, 1994; 79: 1444-1449
4. Bernard, L, Babajko, S, Binoux, M, Ricort, JM. The amino-terminal region of insulin-like growth factor binding protein-3, (1-95)IGFBP-3, induces apoptosis of MCF-7 breast carcinoma cells Biochem Biophys Res Commun, 2002; 293: 55-60
5. Botchkarev, VA, Komarova, EA, Siebenhaar, F, Botchkareva, NV, Komarov, PG, Maurer, M, Gilchrest, BA, Gudkov, AV. p53 is essential for chemotherapy-induced hair loss Cancer Res, 2000; 60: 5002-5006
6. Botchkarev, VA, Komarova, EA, Siebenhaar, F, Botchkareva, NV, Sharov, AA, Komarov, PG, Maurer, M, Gudkov, AV, Gilchrest, BA. p53 involvement in the control of murine hair follicle regression Am J Pathol, 2001; 158: 1913-1919
7. Boukamp, P, Petrussevska, RT, Breitkreuz, D, Hornung, J, Markham, A, Fusenig, NE. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line J Cell Biol, 1988; 106: 761-771
8. Brown, DB, Peritz, AE, Mitchell, DL, Chiarello, S, Uitto, J, Gasparro, FP. Common fluorescent sunlamps are an inappropriate substitute for sunlight Photochem Photobiol, 2000; 72: 340-344
9. Buckbinder, L, Talbott, R, Velasco-Miguel, S, Takenaka, I, Faha, B, Seizinger, BR, Kley, N. Induction of the growth inhibitor IGF-binding protein 3 by p53 Nature, 1995; 377: 646-649
10. Butt, AJ, Williams, AC. IGFBP-3 and apoptosis - a license to kill? Apoptosis, 2001; 6: 199-205
11. Chaturvedi, V, Qin, JZ, Denning, MF, Choubey, D, Diaz, MO, Nickoloff, BJ. Apoptosis in proliferating, senescent, and immortalized keratinocytes J Biol Chem, 1999; 274: 23358-23367
12. Chaturvedi, V, Qin, JZ, Denning, MF, Choubey, D, Diaz, MO, Nickoloff, BJ. Abnormal NF-kappaB signaling pathway with enhanced susceptibility to apoptosis in immortalized keratinocytes J Dermatol Sci, 2001; 26: 67-78
13. Collard, TJ, Guy, M, Butt, AJ, Perks, CM, Holly, JM, Paraskeva, C, Williams, AC. Transcriptional upregulation of the insulin-like growth factor binding protein IGFBP-3 by sodium butyrate increases IGF-independent apoptosis in human colonic adenoma-derived epithelial cells Carcinogenesis, 2003; 24: 393-401
14. Conover, CA. Potentiation of insulin-like growth factor (IGF) action by IGF binding protein-3: Studies of underlying mechanism Endocrinology, 1992; 130: 3191-3199
15. Decraene, D, Agostinis, P, Bouillon, R, Degreef, H, Garmyn, M. Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes J Biol Chem, 2002; 277: 32587-32595
16. Decraene, D, Van Laethem, A, Agostinis, P, De Peuter, L, Degreef, H, Bouillon, R, Garmyn, M. AKT status controls susceptibility of malignant keratinocytes to the early-activated and UVB-induced apoptotic pathway J Investig Dermatol, 2004; 123: 207-212
17. DiGiovanni, J, Bol, DK, Wilker, E, Beltran, L, Carbajal, S, Moats, S, Ramirez, A, Jorcano, J, Kiguchi, K. Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion Cancer Res, 2000; 60: 1561-1570
18. Edmondson, SR, Murashita, MM, Russo, VC, Wraight, CJ, Werther, GA. Expression of insulin-like growth factor binding protein-3 (IGFBP-3) in human keratinocytes is regulated by EGF and TGFbeta1 J Cell Physiol, 1999; 179: 201-207
19. Edmondson, SR, Werther, GA, Wraight, CJ. Calcium regulates the expression of insulin-like growth factor binding protein-3 by the human keratinocyte cell line HaCaT J Investig Dermatol, 2001; 116: 491-497
20. Edmondson, SR, Thumiger, SP, Werther, GA, Wraight, CJ. Epidermal homeostasis: The role of the growth hormone and insulin-like growth factor systems Endocr Rev, 2003; 24: 737-764
21. Edmondson, SR, Thumiger, SP, Kaur, P, Loh, B, Koelmeyer, R, Li, A, Silha, JV, Murphy, LJ, Wraight, CJ, Werther, GA. Insulin-like growth factor binding protein-3 (IGFBP-3) localizes to and modulates proliferative epidermal keratinocytes in vivo Br J Dermatol, 2005; 152: 225-230
22. Firth, SM, Baxter, RC. Cellular actions of the insulin-like growth factor binding proteins Endocr Rev, 2002; 23: 824-854
23. Gasparro, FP, Brown, DB. Photobiology 102: UV sources and dosimetry - the proper use and measurement of "photons as a reagent" J Investig Dermatol, 2000; 114: 613-615
24. Grimberg, A, Liu, B, Bannerman, P, El-Deiry, WS, Cohen, P. IGFBP-3 mediates p53-induced apoptosis during serum starvation Int J Oncol, 2002; 21: 327-335
25. Heron-Milhavet, L, Karas, M, Goldsmith, CM, Baum, BJ, LeRoith, D. Insulin-like growth factor-I (IGF-I) receptor activation rescues UV-damaged cells through a p38 signaling pathway. Potential role of the IGF-I receptor in DNA repair J Biol Chem, 2001; 276: 18185-18192
26. Hodak, E, Gottlieb, AB, Anzilotti, M, Krueger, JG. The insulin-like growth factor 1 receptor is expressed by epithelial cells with proliferative potential in human epidermis and skin appendages: Correlation of increased expression with epidermal hyperplasia J Investig Dermatol, 1996; 106: 564-570
27. Hossenlopp, P, Seurin, D, Segovia-Quinson, B, Hardouin, S, Binoux, M. Analysis of serum insulin-like growth factor binding proteins using Western blotting: Use of the method for titration of the binding proteins and competitive binding studies Anal Biochem, 1986; 154: 138-143
28. Krane, JF, Gottlieb, AB, Carter, DM, Krueger, JG. The insulin-like growth factor I receptor is overexpressed in psoriatic epidermis, but is differentially regulated from the epidermal growth factor receptor J Exp Med, 1992; 175: 1081-1090
29. Kuhn, C, Hurwitz, SA, Kumar, MG, Cotton, J, Spandau, DF. Activation of the insulin-like growth factor-1 receptor promotes the survival of human keratinocytes following ultraviolet B irradiation Int J Cancer, 1999; 80: 431-438
30. Kulms, D, Schwarz, T. Molecular mechanisms of UV-induced apoptosis Photodermatol Photoimmunol Photomed, 2000; 16: 195-201
31. Lalou, C, Lassarre, C, Binoux, M. A proteolytic fragment of insulin-like growth factor (IGF) binding protein-3 that fails to bind IGF is a cell growth inhibitor Prog Growth Factor Res, 1995; 6: 311-316
32. Lehman, TA, Modali, R, Boukamp, P, Stanek, J, Bennett, WP, Welsh, JA, Metcalf, RA, Stampfer, MR, Fusenig, N, Rogan, EM. et al. p53 mutations in human immortalized epithelial cell lines Carcinogenesis, 1993; 14: 833-839
33. Liu, JP, Baker, J, Perkins, AS, Robertson, EJ, Efstratiadis, A. Mice carrying null mutations of the genes encoding insulin-like growth factor I (IGF-I) and type 1 IGF receptor (Igf1r) Cell, 1993; 75: 59-72
34. McCaig, C, Perks, CM, Holly, JM. Intrinsic actions of IGFBP-3 and IGFBP-5 on Hs578T breast cancer epithelial cells: Inhibition or accentuation of attachment and survival is dependent upon the presence of fibronectin J Cell Sci, 2002; 115: 4293-4303
35. Murashita, MM, Russo, VC, Edmondson, SR, Wraight, CJ, Werther, GA. Identification of insulin-like growth factor binding proteins from cultured human epidermal keratinocytes J Cell Physiol, 1995; 163: 339-345
36. Murray, SA, Zheng, H, Gu, L, Jim Xiao, ZX. IGF-1 activates p21 to inhibit UV-induced cell death Oncogene, 2003; 22: 1703-1711
37. Okada, Y, Yokono, K, Katsuta, A, Yoshida, M, Morita, S, Irino, H, Goto, T, Baba, S, Roth, RA, Shii, K. Development of an assay for bioactive insulin Anal Biochem, 1998; 257: 134-138
38. Qin, JZ, Chaturvedi, V, Denning, MF, Choubey, D, Diaz, MO, Nickoloff, BJ. Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes J Biol Chem, 1999; 274: 37957-37964
39. Qin, JZ, Bacon, PE, Chaturvedi, V, Bonish, B, Nickoloff, BJ. Pathways involved in proliferating, senescent and immortalized keratinocyte cell death mediated by two different TRAIL preparations Exp Dermatol, 2002; 11: 573-583
40. Rajah, R, Lee, KW, Cohen, P. Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: Role of Bcl-2 phosphorylation Cell Growth Differ, 2002; 13: 163-171
41. Rudman, SM, Philpott, MP, Thomas, GA, Kealey, T. The role of IGF-I in human skin and its appendages: Morphogen as well as mitogen? J Investig Dermatol, 1997; 109: 770-777
42. Sadowski, T, Dietrich, S, Koschinsky, F, Sedlacek, R. Matrix metalloproteinase 19 regulates insulin-like growth factor-mediated proliferation, migration, and adhesion in human keratinocytes through proteolysis of insulin-like growth factor binding protein-3 Mol Biol Cell, 2003; 14: 4569-4580
43. Schulz, J, Dettlaff, S, Fritzsche, U, Harms, U, Schiebel, H, Derer, W, Fusenig, NE, Hülsen, A, Böhm, M. The amido black assay: A simple and quantitative multipurpose test of adhesion, proliferation and cytotoxicity in microplate cultures of keratinocytes (HaCaT) and other cell types growing adherently or in suspension J Immunol Methods, 1994; 167: 1-13
44. Soos, MA, Field, CE, Lammers, R, Ullrich, A, Zhang, B, Roth, RA, Andersen, AS, Kjeldsen, T, Siddle, K. A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity J Biol Chem, 1992; 267: 12955-12963
45. Tsubaki, J, Hwa, V, Twigg, SM, Rosenfeld, RG. Differential activation of the IGF binding protein-3 promoter by butyrate in prostate cancer cells Endocrinology, 2002; 143: 1778-1788
46. Wraight, CJ, Murashita, MM, Russo, VC, Werther, GA. A keratinocyte cell line synthesizes a predominant insulin-like growth factor-binding protein (IGFBP-3) that modulates insulin-like growth factor-I action J Investig Dermatol, 1994; 103: 627-631
47. Wraight, CJ, Werther, GA. Insulin-like growth factor-I and epidermal growth factor regulate insulin-like growth factor binding protein-3 (IGFBP-3) in the human keratinocyte cell line HaCaT J Investig Dermatol, 1995; 105: 602-607
48. Wraight, CJ, Edmondson, SR, Fortune, DW, Varigos, G, Werther, GA. Expression of insulin-like growth factor binding protein-3 (IGFBP-3) in the psoriatic lesion J Investig Dermatol, 1997; 108: 452-456
49. Wraight, CJ, White, PJ, McKean, SC, Fogarty, RD, Venables, DJ, Liepe, IJ, Edmondson, SR, Werther, GA. Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides Nat Biotechnol, 2000; 18: 521-526
50. Zadeh, SM, Binoux, M. The 16-kDa proteolytic fragment of insulin-like growth factor (IGF) binding protein-3 inhibits the mitogenic action of fibroblast growth factor on mouse fibroblasts with a targeted disruption of the type 1 IGF receptor gene Endocrinology, 1997; 138: 3069-3072