Influence of lead (Pb2+) on the reactions of in vitro cultured rat aorta to 5-hydroxytryptamine

Toxicology Letters

Volumn 159, Issue 1, 2005, Pages 71-82

  Zhang, Le Feng ^b   Peng, Shuang Qing ^a   Wang, Sheng ^b  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

5 HT; 5 HT2B receptor; Aorta; Lead toxicity; Superoxide; Vascular reactivity

Indexed keywords

ASCORBIC ACID; DIPHENYLIODONIUM SALT; ENZYME INHIBITOR; LEAD ACETATE; NORADRENALIN BITARTRATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SEROTONIN; SEROTONIN 2B RECEPTOR; SUPEROXIDE; ANTIOXIDANT; CATION; LEAD; NORADRENALIN; REACTIVE OXYGEN METABOLITE; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; AORTA CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DRUG MEGADOSE; EXPOSURE; IN VITRO STUDY; INCUBATION TIME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; TIME; TISSUE CULTURE; VASCULAR ENDOTHELIUM; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; THORACIC AORTA; UPREGULATION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; WISTAR RAT;

ANIMALIA; RATTUS NORVEGICUS;

ANIMALS; ANTIOXIDANTS; AORTA, THORACIC; ASCORBIC ACID; BLOTTING, WESTERN; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; LEAD; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NADPH OXIDASE; NOREPINEPHRINE; ONIUM COMPOUNDS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTOR, SEROTONIN, 5-HT2B; SEROTONIN; SUPEROXIDES; UP-REGULATION; VASOCONSTRICTOR AGENTS;

EID: 24944580850     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2005.04.009     Document Type: Article

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