Effect of lead on nitric oxide synthase expression in coronary endothelial cells. Role of superoxide

Hypertension

Volumn 37, Issue 2 I, 2001, Pages 223-226

  Vaziri, Nosratola D ^a,b   Ding, Yaoxian ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Arteries; Blood pressure; Endothelium; Free radicals; Lead; Nitric oxide

Indexed keywords

ANTIOXIDANT; LAZAROID; LEAD ACETATE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TEMPOL;

ARTICLE; BIOAVAILABILITY; BLOOD PRESSURE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM CELL; ENZYME INACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERTENSION; LONG TERM EXPOSURE; OXIDATIVE STRESS; POSITIVE FEEDBACK; PRIORITY JOURNAL;

EID: 0035094460     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.37.2.223     Document Type: Article

References (11)

1. Altered nitric oxide metabolism and increased oxygen free radical activity in lead-induced hypertension: Effect of lazaroid therapy
2. Lead-induced hypertension: Interplay of nitric oxide and reactive oxygen species
3. Nitric oxide synthase expression in the course of lead-induced hypertension
4. Increased nitric oxide inactivation by reactive oxygen species in lead- induced hypertension
5. Lead promotes hydroxyl radical generation and lipid peroxidation in cultured aortic endothelial cells
6. Lead-induced hypertension: Increased hydroxyl radical production
7. cGMP-mediated negative-feedback regulation of endothelial nitric oxide synthase expression by nitric oxide
8. Nifedipine and diltiazem but not verapamil up-regulate endothelial nitric-oxide synthase expression
9. Lead-induced hypertension. 11: Response to sequential infusions of L- arginine, superoxide dismutase, and nitro-prusside
10. A novel metal-free low molecular weight superoxide dismutase mimic
11. Biologically active metal-independent superoxide dismutase mimics